{"id":"https://openalex.org/W2007995470","doi":"https://doi.org/10.1176/ajp.127.4.462","title":"Digital Computer Analyzed Sleep and Resting EEG During Haloperidol Treatment","display_name":"Digital Computer Analyzed Sleep and Resting EEG During Haloperidol Treatment","publication_year":1970,"publication_date":"1970-10-01","ids":{"openalex":"https://openalex.org/W2007995470","doi":"https://doi.org/10.1176/ajp.127.4.462","mag":"2007995470","pmid":"https://pubmed.ncbi.nlm.nih.gov/4318894"},"language":"en","primary_location":{"id":"doi:10.1176/ajp.127.4.462","doi":"https://doi.org/10.1176/ajp.127.4.462","is_oa":false,"landing_page_url":"https://doi.org/10.1176/ajp.127.4.462","pdf_url":null,"source":{"id":"https://openalex.org/S116025658","display_name":"American Journal of Psychiatry","issn_l":"0002-953X","issn":["0002-953X","1535-7228"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316602","host_organization_name":"American Psychiatric Association","host_organization_lineage":["https://openalex.org/P4310316602"],"host_organization_lineage_names":["American Psychiatric Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"TURAN M. ITIL","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"TURAN M. ITIL","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026243324","display_name":"Patrick John Gannon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"PATRICK GANNON","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016291944","display_name":"William W.Y. Hsu","orcid":"https://orcid.org/0000-0002-5168-070X","observed_orcids":["https://orcid.org/0000-0002-5168-070X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"WILLIAM HSU","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088221242","display_name":"H Klingenberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"HELEN KLINGENBERG","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.4506,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.9570118,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"127","issue":"4","first_page":"462","last_page":"471"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.8618000149726868,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.8618000149726868,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.06560000032186508,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.029100000858306885,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/haloperidol","display_name":"haloperidol","score":1.0},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.656000018119812},{"id":"https://openalex.org/keywords/sleep-eeg","display_name":"sleep EEG","score":0.949999988079071},{"id":"https://openalex.org/keywords/resting-state-eeg","display_name":"resting-state EEG","score":0.9509999752044678},{"id":"https://openalex.org/keywords/slow-waves","display_name":"slow waves","score":0.746999979019165},{"id":"https://openalex.org/keywords/sleep-stages","display_name":"sleep stages","score":0.6480000019073486},{"id":"https://openalex.org/keywords/antipsychotic-effects","display_name":"antipsychotic effects","score":0.8149999976158142},{"id":"https://openalex.org/keywords/digital-computer-analysis","display_name":"digital computer analysis","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C2780948584","wikidata":"https://www.wikidata.org/wiki/Q251347","display_name":"Haloperidol","level":3,"score":0.8949482440948486},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.7921632528305054},{"id":"https://openalex.org/C110539466","wikidata":"https://www.wikidata.org/wiki/Q3964845","display_name":"Slow-wave sleep","level":3,"score":0.6840659976005554},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6342495679855347},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.49090248346328735},{"id":"https://openalex.org/C112144039","wikidata":"https://www.wikidata.org/wiki/Q4994651","display_name":"K-complex","level":4,"score":0.47782376408576965},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.45778077840805054},{"id":"https://openalex.org/C2910364982","wikidata":"https://www.wikidata.org/wiki/Q35831","display_name":"Sleep Stages","level":4,"score":0.4258696436882019},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.39969611167907715},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3819788992404938},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.32801002264022827},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.29018014669418335},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.07160595059394836},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D003201","descriptor_name":"Computers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004576","descriptor_name":"Electromyography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005133","descriptor_name":"Eye Movements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011352","descriptor_name":"Procyclidine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012894","descriptor_name":"Sleep Stages","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1176/ajp.127.4.462","doi":"https://doi.org/10.1176/ajp.127.4.462","is_oa":false,"landing_page_url":"https://doi.org/10.1176/ajp.127.4.462","pdf_url":null,"source":{"id":"https://openalex.org/S116025658","display_name":"American Journal of Psychiatry","issn_l":"0002-953X","issn":["0002-953X","1535-7228"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316602","host_organization_name":"American Psychiatric Association","host_organization_lineage":["https://openalex.org/P4310316602"],"host_organization_lineage_names":["American Psychiatric Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Psychiatry","raw_type":"journal-article"},{"id":"pmid:4318894","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4318894","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of psychiatry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W582278227","https://openalex.org/W1963742344","https://openalex.org/W1976318001","https://openalex.org/W1988438870","https://openalex.org/W2029520770","https://openalex.org/W2088002018","https://openalex.org/W2099891416","https://openalex.org/W2743523868"],"related_works":["https://openalex.org/W2014113089","https://openalex.org/W2315191774","https://openalex.org/W2055199479","https://openalex.org/W1966391641","https://openalex.org/W4391772942","https://openalex.org/W1999229019","https://openalex.org/W2039465869","https://openalex.org/W270999626","https://openalex.org/W1968587348","https://openalex.org/W2031211156"],"abstract_inverted_index":{"The":[0,50],"authors":[1],"studied":[2],"the":[3,41,53],"effects":[4],"of":[5,13],"haloperidol":[6],"on":[7],"resting":[8,31],"and":[9,24,32,69],"all-night":[10],"sleep":[11,33,46],"EEGs":[12,34],"chronic":[14,62],"schizophrenic":[15,63],"patients.":[16],"There":[17],"was":[18],"a":[19,38],"decrease":[20,39],"in":[21,27,40,44],"slow":[22],"waves":[23],"an":[25],"increase":[26],"fast":[28],"activity":[29],"during":[30,48],"as":[35,37],"well":[36],"time":[42],"spent":[43],"deep":[45],"stages":[47],"sleep.":[49],"findings":[51],"support":[52],"hypothesis":[54],"that":[55,57],"compounds":[56],"are":[58],"most":[59],"effective":[60],"with":[61],"patients":[64],"have":[65],"both":[66],"central":[67],"inhibitory":[68],"stimulating":[70],"components.":[71]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}