{"id":"https://openalex.org/W2007992826","doi":"https://doi.org/10.1117/12.909185","title":"Use of the second harmonic generation microscopy to evaluate chondrogenic differentiation of mesenchymal stem cells for cartilage repair","display_name":"Use of the second harmonic generation microscopy to evaluate chondrogenic differentiation of mesenchymal stem cells for cartilage repair","publication_year":2012,"publication_date":"2012-02-08","ids":{"openalex":"https://openalex.org/W2007992826","doi":"https://doi.org/10.1117/12.909185","mag":"2007992826"},"language":"en","primary_location":{"id":"doi:10.1117/12.909185","doi":"https://doi.org/10.1117/12.909185","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.909185","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://repositorio.unicamp.br/jspui/handle/REPOSIP/348111","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019710751","display_name":"Pedro Bordeaux\u2010Rego","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"P. Bordeaux-Rego","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061310394","display_name":"Mariana Ozello Baratti","orcid":"https://orcid.org/0000-0002-4300-2466","observed_orcids":["https://orcid.org/0000-0002-4300-2466"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M. O. Baratti","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081834539","display_name":"Adriana Silva Santos Duarte","orcid":"https://orcid.org/0000-0002-6243-6761","observed_orcids":["https://orcid.org/0000-0002-6243-6761","https://orcid.org/0000-0002-5989-8316"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"A. S. S. Duarte","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017465800","display_name":"Thiago Borsoi Ribeiro","orcid":"https://orcid.org/0000-0001-5231-5766","observed_orcids":["https://orcid.org/0000-0001-5231-5766"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"T. B. Ribeiro","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058922426","display_name":"M. F. Andreoli-Risso","orcid":"https://orcid.org/0000-0002-3031-0152","observed_orcids":["https://orcid.org/0000-0002-3031-0152"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M. F. Andreoli-Risso","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049832305","display_name":"Benedicto de Campos Vidal","orcid":"https://orcid.org/0000-0003-0285-1653","observed_orcids":["https://orcid.org/0000-0003-0285-1653"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"B. Vidal","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101514559","display_name":"Jo\u00e3o Batista de Miranda","orcid":"https://orcid.org/0000-0001-9128-0295","observed_orcids":["https://orcid.org/0000-0001-9128-0295"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"J. B. Miranda","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085969367","display_name":"Javier F. Adur","orcid":"https://orcid.org/0000-0003-2176-2226","observed_orcids":["https://orcid.org/0000-0003-2176-2226"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]},{"id":"https://openalex.org/I62318804","display_name":"Universidad Nacional de Entre R\u00edos","ror":"https://ror.org/01wgfva68","country_code":"AR","type":"education","lineage":["https://openalex.org/I62318804"]}],"countries":["AR","BR"],"is_corresponding":false,"raw_author_name":"J. Adur","raw_affiliation_strings":["National Univ. of Entre Rios (Argentina)","Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Univ. of Entre Rios (Argentina)","institution_ids":["https://openalex.org/I62318804"]},{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009649915","display_name":"Andr\u00e9 A. de Thomaz","orcid":"https://orcid.org/0000-0002-8318-4428","observed_orcids":["https://orcid.org/0000-0002-8318-4428"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"A. A. de Thomaz","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110061487","display_name":"Vitor B. Pelegati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"V. B. Pelegati","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067713063","display_name":"Fernando Ferreira Costa","orcid":"https://orcid.org/0000-0002-4632-572X","observed_orcids":["https://orcid.org/0000-0002-4632-572X","https://orcid.org/0009-0002-1844-2870"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"F. F. Costa","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014581818","display_name":"Hernandes F. Carvalho","orcid":"https://orcid.org/0000-0002-3080-9447","observed_orcids":["https://orcid.org/0000-0002-3080-9447"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"H. F. Carvalho","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108085082","display_name":"Carlos L. Cesar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C. L. Cesar","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016761570","display_name":"\u00c2ngela Cristina Malheiros Luzo","orcid":"https://orcid.org/0000-0002-1422-9119","observed_orcids":["https://orcid.org/0000-0002-1422-9119"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"A. Luzo","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052529953","display_name":"Sara Teresinha Olalla Saad","orcid":"https://orcid.org/0000-0003-0809-8068","observed_orcids":["https://orcid.org/0000-0003-0809-8068"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"S. T. Olalla Saad","raw_affiliation_strings":["Univ. Estadual de Campinas (Brazil)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Estadual de Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":11.1667,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.95514019,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"8226","issue":null,"first_page":"82263N","last_page":"82263N"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.02630000002682209,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/second-harmonic-generation-microscopy","display_name":"second harmonic generation microscopy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9580000042915344},{"id":"https://openalex.org/keywords/chondrogenic-differentiation","display_name":"chondrogenic differentiation","score":0.996999979019165},{"id":"https://openalex.org/keywords/cartilage-repair","display_name":"cartilage repair","score":0.9449999928474426},{"id":"https://openalex.org/keywords/articular-cartilage-injury","display_name":"articular cartilage damage","score":0.9399999976158142},{"id":"https://openalex.org/keywords/collagen-fibril-organization","display_name":"collagen fibril organization","score":0.8560000061988831},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8130000233650208},{"id":"https://openalex.org/keywords/rabbit-knee-model","display_name":"rabbit knee model","score":0.8569999933242798}],"concepts":[{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.8644112944602966},{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.8082937002182007},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.7165683507919312},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5609609484672546},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.5568559169769287},{"id":"https://openalex.org/C2780024818","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Hyaline cartilage","level":5,"score":0.5433029532432556},{"id":"https://openalex.org/C2778414984","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biomaterial","level":2,"score":0.4975595772266388},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.49380335211753845},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4808817207813263},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4714718163013458},{"id":"https://openalex.org/C13685319","wikidata":"https://www.wikidata.org/wiki/Q7607302","display_name":"Stem cell transplantation for articular cartilage repair","level":5,"score":0.4489358365535736},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.4234447479248047},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.38848233222961426},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.38065823912620544},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32301753759384155},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.30124741792678833},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28765392303466797},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.2516692876815796},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.19726347923278809},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.19034746289253235},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.18000328540802002},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1698663830757141},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.12144002318382263},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1117/12.909185","doi":"https://doi.org/10.1117/12.909185","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.909185","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmh:oai:repositorio.unicamp.br:REPOSIP/348111","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.unicamp.br/jspui/handle/REPOSIP/348111","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"WOS","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":{"id":"pmh:oai:repositorio.unicamp.br:REPOSIP/348111","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.unicamp.br/jspui/handle/REPOSIP/348111","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"WOS","raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2029114553","https://openalex.org/W2546604265","https://openalex.org/W2765737047","https://openalex.org/W2363828458","https://openalex.org/W2050105145","https://openalex.org/W2142400618","https://openalex.org/W2069985080","https://openalex.org/W2035675238","https://openalex.org/W2138912023","https://openalex.org/W2733610592"],"abstract_inverted_index":{"Articular":[0],"cartilage":[1,62,210],"injury":[2],"remains":[3],"one":[4,86,91],"of":[5,23,29,39,56,63,83,115,131,156,161,171,202,205],"the":[6,24,33,52,60,81,84,99,112,116,132,137,145,148,162,181,200,203],"major":[7],"concerns":[8],"in":[9,59,111,128,144,174,180,199],"orthopedic":[10],"surgery.":[11],"Mesenchymal":[12],"stem":[13,41],"cell":[14,207],"(MSC)":[15],"transplantation":[16],"has":[17],"been":[18],"introduced":[19],"to":[20,35,50,197],"avoid":[21],"some":[22],"side":[25],"effects":[26],"and":[27,54,90,104,108,142],"complications":[28],"current":[30],"techniques..":[31],"With":[32],"aim":[34],"evaluate":[36],"chondrogenic":[37],"differentiation":[38],"mesenchymal":[40],"cells,":[42],"we":[43],"used":[44,183],"Second":[45],"Harmonic":[46],"Generation":[47],"(SHG)":[48],"microscopy":[49,191],"analyze":[51],"aggregation":[53],"orientation":[55],"collagen":[57,75,106,138,149],"fibrils":[58],"hyaline":[61],"rabbit":[64,100],"knees.":[65],"The":[66,122],"experiment":[67],"was":[68],"performed":[69],"using":[70],"implants":[71],"with":[72,135,154,177],"type":[73],"II":[74],"hydrogel":[76],"(a":[77],"biomaterial":[78],"that":[79,189],"mimics":[80],"microenvironment":[82],"cartilage),":[85],"implant":[87],"containing":[88],"MSC":[89,94,136,178],"other":[92],"without":[93],"(control).":[95],"After":[96],"10":[97],"weeks,":[98],"knees":[101,175,182],"were":[102,118],"dissected":[103],"fibril":[105],"distribution":[107],"spatial":[109],"organization":[110],"extracellular":[113],"matrix":[114],"lesions":[117,134,163,172],"verified":[119],"by":[120],"SHG.":[121],"result":[123],"showed":[124],"significant":[125],"differences,":[126],"whereas":[127],"histological":[129],"sections":[130,147],"cartilaginous":[133],"fibers":[139,150],"are":[140,151],"organized":[141],"regular;":[143],"control":[146],"more":[152],"irregular,":[153],"absence":[155],"cells.":[157],"A":[158],"macroscopic":[159],"analysis":[160],"confirmed":[164],"this":[165],"difference,":[166],"showing":[167],"a":[168],"greater":[169],"percentage":[170],"filling":[173],"treated":[176],"than":[179],"as":[184],"controls.":[185],"This":[186],"study":[187],"demonstrates":[188],"SHG":[190],"will":[192],"be":[193],"an":[194],"excellent":[195],"tool":[196],"help":[198],"evaluation":[201],"effectiveness":[204],"MSC-based":[206],"therapy":[208],"for":[209],"repair.":[211]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}