{"id":"https://openalex.org/W2007948481","doi":"https://doi.org/10.1038/333475a0","title":"Chemical probing of homopurine-homopyrimidine mirror repeats in supercoiled DNA","display_name":"Chemical probing of homopurine-homopyrimidine mirror repeats in supercoiled DNA","publication_year":1988,"publication_date":"1988-06-01","ids":{"openalex":"https://openalex.org/W2007948481","doi":"https://doi.org/10.1038/333475a0","mag":"2007948481","pmid":"https://pubmed.ncbi.nlm.nih.gov/3374588"},"language":"en","primary_location":{"id":"doi:10.1038/333475a0","doi":"https://doi.org/10.1038/333475a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/333475a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032108915","display_name":"Oleg N. Voloshin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131892","display_name":"Institute of Molecular Genetics","ror":"https://ror.org/03apz2q12","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210131892"]},{"id":"https://openalex.org/I4405285364","display_name":"Academy of Sciences of the Soviet Union","ror":"https://ror.org/059mhqh10","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4405285364"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"O. N. Voloshin","raw_affiliation_strings":["Institute of Molecular Genetics, USSR Academy of Sciences, Moscow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038374223","display_name":"Sergei M. Mirkin","orcid":"https://orcid.org/0000-0003-4576-7582","observed_orcids":["https://orcid.org/0000-0003-4576-7582"]},"institutions":[{"id":"https://openalex.org/I4210131892","display_name":"Institute of Molecular Genetics","ror":"https://ror.org/03apz2q12","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210131892"]},{"id":"https://openalex.org/I4405285364","display_name":"Academy of Sciences of the Soviet Union","ror":"https://ror.org/059mhqh10","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4405285364"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"S. M. Mirkin","raw_affiliation_strings":["Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","Institute of Molecular Genetics, USSR Academy of Sciences, Moscow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]},{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037931247","display_name":"Victor I. Lyamichev","orcid":"https://orcid.org/0000-0001-5797-3522","observed_orcids":["https://orcid.org/0000-0001-5797-3522"]},"institutions":[{"id":"https://openalex.org/I4210131892","display_name":"Institute of Molecular Genetics","ror":"https://ror.org/03apz2q12","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210131892"]},{"id":"https://openalex.org/I4405285364","display_name":"Academy of Sciences of the Soviet Union","ror":"https://ror.org/059mhqh10","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4405285364"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"V. I. Lyamichev","raw_affiliation_strings":["Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","Institute of Molecular Genetics, USSR Academy of Sciences, Moscow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]},{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051089827","display_name":"Boris P. Belotserkovskii","orcid":"https://orcid.org/0000-0002-1570-9923","observed_orcids":["https://orcid.org/0000-0002-1570-9923"]},"institutions":[{"id":"https://openalex.org/I4210131892","display_name":"Institute of Molecular Genetics","ror":"https://ror.org/03apz2q12","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210131892"]},{"id":"https://openalex.org/I4405285364","display_name":"Academy of Sciences of the Soviet Union","ror":"https://ror.org/059mhqh10","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4405285364"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"B. P. Belotserkovskii","raw_affiliation_strings":["Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","Institute of Molecular Genetics, USSR Academy of Sciences, Moscow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]},{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110131375","display_name":"Maxim D. Frank-Kamenetskii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131892","display_name":"Institute of Molecular Genetics","ror":"https://ror.org/03apz2q12","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210131892"]},{"id":"https://openalex.org/I4405285364","display_name":"Academy of Sciences of the Soviet Union","ror":"https://ror.org/059mhqh10","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4405285364"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"M. D. Frank-Kamenetskii","raw_affiliation_strings":["Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","Institute of Molecular Genetics, USSR Academy of Sciences, Moscow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, 123182, USSR","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]},{"raw_affiliation_string":"Institute of Molecular Genetics, USSR Academy of Sciences, Moscow","institution_ids":["https://openalex.org/I4210131892","https://openalex.org/I4405285364"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":9.8825,"has_fulltext":false,"cited_by_count":175,"citation_normalized_percentile":{"value":0.98764294,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"333","issue":"6172","first_page":"475","last_page":"476"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/supercoiled-dna","display_name":"supercoiled DNA","score":0.9079999923706055},{"id":"https://openalex.org/keywords/triplex-dna","display_name":"triplex DNA","score":0.7860000133514404},{"id":"https://openalex.org/keywords/low-ph","display_name":"low pH","score":0.8579999804496765},{"id":"https://openalex.org/keywords/diethyl-pyrocarbonate","display_name":"diethylpyrocarbonate","score":0.9490000009536743},{"id":"https://openalex.org/keywords/dna-conformation","display_name":"DNA conformation","score":0.43700000643730164}],"concepts":[{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.716086745262146},{"id":"https://openalex.org/C158456008","wikidata":"https://www.wikidata.org/wiki/Q412639","display_name":"DNA supercoil","level":4,"score":0.7038540840148926},{"id":"https://openalex.org/C2776476023","wikidata":"https://www.wikidata.org/wiki/Q188261","display_name":"Purine","level":3,"score":0.6724029183387756},{"id":"https://openalex.org/C188374626","wikidata":"https://www.wikidata.org/wiki/Q5914418","display_name":"Mirror symmetry","level":2,"score":0.5969141721725464},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5472897291183472},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5460193753242493},{"id":"https://openalex.org/C169586020","wikidata":"https://www.wikidata.org/wiki/Q3780159","display_name":"Purine metabolism","level":3,"score":0.5274239778518677},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3910459280014038},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.33664238452911377},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.28323298692703247},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2493053376674652},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.19943949580192566},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07156378030776978},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004047","descriptor_name":"Diethyl Pyrocarbonate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004278","descriptor_name":"DNA, Superhelical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013463","descriptor_name":"Sulfuric Acid Esters","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/333475a0","doi":"https://doi.org/10.1038/333475a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/333475a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:3374588","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3374588","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1480653299","https://openalex.org/W1992595091","https://openalex.org/W1993005791","https://openalex.org/W2009378502","https://openalex.org/W2028126899","https://openalex.org/W2036277582","https://openalex.org/W2047726221","https://openalex.org/W2050822975","https://openalex.org/W2080040426","https://openalex.org/W2081446791","https://openalex.org/W2092716257","https://openalex.org/W2149177798"],"related_works":["https://openalex.org/W2081446791","https://openalex.org/W2057556292","https://openalex.org/W2036277582","https://openalex.org/W7097923404","https://openalex.org/W2005417313","https://openalex.org/W1993046081","https://openalex.org/W1990018313","https://openalex.org/W1993005791","https://openalex.org/W2044537778","https://openalex.org/W1966342019"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}