{"id":"https://openalex.org/W2007675633","doi":"https://doi.org/10.1182/blood-2008-01-131813","title":"Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells","display_name":"Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells","publication_year":2008,"publication_date":"2008-05-17","ids":{"openalex":"https://openalex.org/W2007675633","doi":"https://doi.org/10.1182/blood-2008-01-131813","mag":"2007675633","pmid":"https://pubmed.ncbi.nlm.nih.gov/18487509","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2481532"},"language":"en","primary_location":{"id":"doi:10.1182/blood-2008-01-131813","doi":"https://doi.org/10.1182/blood-2008-01-131813","is_oa":true,"landing_page_url":"https://doi.org/10.1182/blood-2008-01-131813","pdf_url":"https://ashpublications.org/blood/article-pdf/112/3/644/1306977/zh801508000644.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ashpublications.org/blood/article-pdf/112/3/644/1306977/zh801508000644.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012942304","display_name":"Jose Maria Polo","orcid":"https://orcid.org/0000-0002-2531-778X","observed_orcids":["https://orcid.org/0000-0002-2531-778X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jose M. Polo","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY;","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044113220","display_name":"Weimin Ci","orcid":"https://orcid.org/0000-0002-4111-5360","observed_orcids":["https://orcid.org/0000-0002-4111-5360"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Weimin Ci","raw_affiliation_strings":["Division of Hematology and Medical Oncology and Department of Medicine, Weill Cornell College of Medicine, New York, NY; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology and Department of Medicine, Weill Cornell College of Medicine, New York, NY; and","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034992183","display_name":"Jonathan D. Licht","orcid":"https://orcid.org/0000-0002-3942-1369","observed_orcids":["https://orcid.org/0000-0002-3942-1369"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan D. Licht","raw_affiliation_strings":["Division of Hematology/Oncology and Department of Medicine, Northwestern University School of Medicine, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology and Department of Medicine, Northwestern University School of Medicine, Chicago, IL","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019770989","display_name":"Ari M. Melnick","orcid":"https://orcid.org/0000-0002-8074-2287","observed_orcids":["https://orcid.org/0000-0002-8074-2287"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ari Melnick","raw_affiliation_strings":["Division of Hematology and Medical Oncology and Department of Medicine, Weill Cornell College of Medicine, New York, NY; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology and Department of Medicine, Weill Cornell College of Medicine, New York, NY; and","institution_ids":["https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5012942304","https://openalex.org/A5044113220"],"corresponding_institution_ids":["https://openalex.org/I129975664","https://openalex.org/I4387153466"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":1.0759,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.74775245,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"112","issue":"3","first_page":"644","last_page":"651"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8363999724388123,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8363999724388123,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.08640000224113464,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.04100000113248825,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bcl6","display_name":"BCL6","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cd40-signaling","display_name":"CD40 signaling","score":0.996999979019165},{"id":"https://openalex.org/keywords/germinal-center-b-cells","display_name":"germinal center B cells","score":0.9470000267028809},{"id":"https://openalex.org/keywords/centroblasts","display_name":"centroblasts","score":0.8109999895095825},{"id":"https://openalex.org/keywords/transcriptional-repression","display_name":"transcriptional repression","score":0.7789999842643738},{"id":"https://openalex.org/keywords/histone-acetylation","display_name":"histone acetylation","score":0.9020000100135803},{"id":"https://openalex.org/keywords/t-cell-b-cell-interaction","display_name":"T cell-B cell interaction","score":0.5249999761581421},{"id":"https://openalex.org/keywords/cd23","display_name":"CD23","score":0.6209999918937683},{"id":"https://openalex.org/keywords/attenuated-total-reflectance","display_name":"ATR","score":0.9300000071525574},{"id":"https://openalex.org/keywords/tp53","display_name":"TP53","score":0.9980000257492065},{"id":"https://openalex.org/keywords/somatic-hypermutation","display_name":"somatic hypermutation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/class-switch-recombination","display_name":"class switch recombination","score":0.8109999895095825},{"id":"https://openalex.org/keywords/b-cell-differentiation","display_name":"B cell differentiation","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C186310378","wikidata":"https://www.wikidata.org/wiki/Q941796","display_name":"Psychological repression","level":4,"score":0.6935011148452759},{"id":"https://openalex.org/C39347974","wikidata":"https://www.wikidata.org/wiki/Q21135811","display_name":"CD40","level":4,"score":0.5600627660751343},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5392758846282959},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4708520770072937},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40284377336502075},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39405500888824463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3697374761104584},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33947834372520447},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3243677020072937},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2229059338569641},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014066","descriptor_name":"Palatine Tonsil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D019013","descriptor_name":"CD40 Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D021581","descriptor_name":"Active Transport, Cell Nucleus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051560","descriptor_name":"Proto-Oncogene Proteins c-bcl-6","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D056985","descriptor_name":"Nuclear Receptor Co-Repressor 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1182/blood-2008-01-131813","doi":"https://doi.org/10.1182/blood-2008-01-131813","is_oa":true,"landing_page_url":"https://doi.org/10.1182/blood-2008-01-131813","pdf_url":"https://ashpublications.org/blood/article-pdf/112/3/644/1306977/zh801508000644.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1487858","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2481532","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2481532","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2481532","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Text"},{"id":"pmid:18487509","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18487509","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1182/blood-2008-01-131813","doi":"https://doi.org/10.1182/blood-2008-01-131813","is_oa":true,"landing_page_url":"https://doi.org/10.1182/blood-2008-01-131813","pdf_url":"https://ashpublications.org/blood/article-pdf/112/3/644/1306977/zh801508000644.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5208877052","display_name":"The PLZF Protein of t(11;17)-Promyelocytic Leukemia","funder_award_id":"R01CA059936","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7957707465","display_name":"Transcriptional silencing by the BCL6 oncoprotein","funder_award_id":"R01CA104348","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306902","display_name":"Chemotherapy Foundation","ror":"https://ror.org/02rb2sh19"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2007675633.pdf","grobid_xml":"https://content.openalex.org/works/W2007675633.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1488731933","https://openalex.org/W1506411711","https://openalex.org/W1534592832","https://openalex.org/W1566926046","https://openalex.org/W1970854602","https://openalex.org/W1973476558","https://openalex.org/W1973587254","https://openalex.org/W1976759658","https://openalex.org/W1989134497","https://openalex.org/W1989914829","https://openalex.org/W1991311051","https://openalex.org/W1994031217","https://openalex.org/W1995204178","https://openalex.org/W2002451995","https://openalex.org/W2004067791","https://openalex.org/W2006885289","https://openalex.org/W2009859686","https://openalex.org/W2014113929","https://openalex.org/W2017358644","https://openalex.org/W2038476365","https://openalex.org/W2044365745","https://openalex.org/W2045715956","https://openalex.org/W2052373759","https://openalex.org/W2076543297","https://openalex.org/W2079265644","https://openalex.org/W2085524373","https://openalex.org/W2091213817","https://openalex.org/W2093846063","https://openalex.org/W2104601806","https://openalex.org/W2106903691","https://openalex.org/W2110328765","https://openalex.org/W2114334107","https://openalex.org/W2121235025","https://openalex.org/W2122874647","https://openalex.org/W2146573874","https://openalex.org/W2147362602","https://openalex.org/W2149794922","https://openalex.org/W2153598858","https://openalex.org/W2160521571","https://openalex.org/W2172230584","https://openalex.org/W2172295707","https://openalex.org/W6631893276"],"related_works":["https://openalex.org/W2566016429","https://openalex.org/W2009859686","https://openalex.org/W4231033728","https://openalex.org/W2006885289","https://openalex.org/W2056939983","https://openalex.org/W2540415762","https://openalex.org/W7099372232","https://openalex.org/W2753521119","https://openalex.org/W2612221206","https://openalex.org/W2128241795"],"abstract_inverted_index":{"Germinal":[0],"center":[1],"(GC)":[2],"B":[3,35,189],"cells":[4,38,46,67,173],"undergo":[5,157,193],"somatic":[6],"hypermutation,":[7],"class":[8],"switch":[9],"recombination,":[10],"and":[11,36,105,115],"rapid":[12],"clonal":[13],"expansion":[14],"to":[15,49,73,85,98,120,131,133,152,174],"produce":[16],"high-affinity":[17],"antibodies.":[18],"The":[19],"BCL6":[20,75,84,108,126],"transcriptional":[21],"repressor":[22],"facilitates":[23],"this":[24,69,139],"phenotype":[25],"because":[26],"it":[27,93],"can":[28,39],"repress":[29],"DNA":[30],"damage":[31],"checkpoint":[32],"genes.":[33],"GC":[34,169],"T":[37,45,66,172],"make":[40],"transient":[41,122,164],"direct":[42],"physical":[43],"contact;":[44],"were":[47],"observed":[48],"be":[50,72],"associated":[51],"with":[52],"dead":[53],"B-cell":[54],"fragments.":[55],"We":[56],"thus":[57],"hypothesized":[58],"that":[59,138,148,163],"one":[60],"function":[61],"of":[62,83,107,118,187,198],"CD40":[63,77,119,165],"signaling":[64,78,166],"from":[65,94],"within":[68],"timeframe":[70],"could":[71,145,192],"modulate":[74],"activity.":[76],"rapidly":[79],"disrupts":[80],"the":[81,87,95,168,182],"ability":[82],"recruit":[86],"SMRT":[88],"corepressor":[89],"complex":[90],"by":[91],"excluding":[92],"nucleus,":[96],"leading":[97],"histone":[99],"acetylation,":[100],"RNA":[101],"polymerase":[102],"II":[103],"processivity,":[104],"activation":[106],"target":[109,127],"genes,":[110],"such":[111],"as":[112],"CD23b,":[113],"ATR,":[114],"TP53.":[116],"Washout":[117],"emulate":[121],"T-cell":[123],"contact":[124],"permitted":[125],"gene":[128],"mRNA":[129],"levels":[130],"return":[132],"their":[134],"repressed":[135],"levels,":[136],"demonstrating":[137],"is":[140],"a":[141],"reversible":[142],"process,":[143],"which":[144,191],"allow":[146,171],"centroblasts":[147,179],"pass":[149],"quality":[150],"control":[151],"either":[153],"continue":[154],"proliferation":[155],"or":[156,195],"terminal":[158],"differentiation.":[159],"These":[160],"data":[161],"suggest":[162],"in":[167],"might":[170],"weed":[175],"out":[176],"heavily":[177],"damaged":[178],"while":[180],"at":[181],"same":[183],"time":[184],"promoting":[185],"survival":[186],"intact":[188],"cells,":[190],"differentiation":[194],"additional":[196],"rounds":[197],"proliferation.":[199]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}