{"id":"https://openalex.org/W2007624331","doi":"https://doi.org/10.1161/01.atv.10.3.394","title":"Relationship between sensitivity to dietary fat and dietary cholesterol.","display_name":"Relationship between sensitivity to dietary fat and dietary cholesterol.","publication_year":1990,"publication_date":"1990-05-01","ids":{"openalex":"https://openalex.org/W2007624331","doi":"https://doi.org/10.1161/01.atv.10.3.394","mag":"2007624331","pmid":"https://pubmed.ncbi.nlm.nih.gov/2344298"},"language":"en","primary_location":{"id":"doi:10.1161/01.atv.10.3.394","doi":"https://doi.org/10.1161/01.atv.10.3.394","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.10.3.394","pdf_url":null,"source":{"id":"https://openalex.org/S4210182225","display_name":"Arteriosclerosis An Official Journal of the American Heart Association Inc","issn_l":"0276-5047","issn":["0276-5047","2330-9180"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis: An Official Journal of the American Heart Association, Inc.","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1161/01.atv.10.3.394","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091197396","display_name":"Peter Marshall Clifton","orcid":"https://orcid.org/0000-0002-6411-626X","observed_orcids":["https://orcid.org/0000-0002-6411-626X"]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210101388","display_name":"Health Sciences and Nutrition","ror":"https://ror.org/0152bt112","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210101388","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"P M Clifton","raw_affiliation_strings":["CSIRO Division of Human Nutrition, Adelaide, South Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Division of Human Nutrition, Adelaide, South Australia","institution_ids":["https://openalex.org/I1292875679","https://openalex.org/I4210101388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075666233","display_name":"Mark Kestin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210101388","display_name":"Health Sciences and Nutrition","ror":"https://ror.org/0152bt112","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210101388","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"M Kestin","raw_affiliation_strings":["CSIRO Division of Human Nutrition, Adelaide, South Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Division of Human Nutrition, Adelaide, South Australia","institution_ids":["https://openalex.org/I1292875679","https://openalex.org/I4210101388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069911770","display_name":"Mavis Abbey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210101388","display_name":"Health Sciences and Nutrition","ror":"https://ror.org/0152bt112","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210101388","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"M Abbey","raw_affiliation_strings":["CSIRO Division of Human Nutrition, Adelaide, South Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Division of Human Nutrition, Adelaide, South Australia","institution_ids":["https://openalex.org/I1292875679","https://openalex.org/I4210101388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044989465","display_name":"McKenna Marie Drysdale","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210101388","display_name":"Health Sciences and Nutrition","ror":"https://ror.org/0152bt112","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210101388","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"M Drysdale","raw_affiliation_strings":["CSIRO Division of Human Nutrition, Adelaide, South Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Division of Human Nutrition, Adelaide, South Australia","institution_ids":["https://openalex.org/I1292875679","https://openalex.org/I4210101388"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063295354","display_name":"Paul John Nestel","orcid":"https://orcid.org/0000-0001-5180-2132","observed_orcids":["https://orcid.org/0000-0001-5180-2132"]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210101388","display_name":"Health Sciences and Nutrition","ror":"https://ror.org/0152bt112","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210101388","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"P J Nestel","raw_affiliation_strings":["CSIRO Division of Human Nutrition, Adelaide, South Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Division of Human Nutrition, Adelaide, South Australia","institution_ids":["https://openalex.org/I1292875679","https://openalex.org/I4210101388"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.507,"has_fulltext":false,"cited_by_count":74,"citation_normalized_percentile":{"value":0.98126532,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"10","issue":"3","first_page":"394","last_page":"401"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.48750001192092896,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.48750001192092896,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.45750001072883606,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.718999981880188},{"id":"https://openalex.org/keywords/egg-yolk-cholesterol","display_name":"egg yolk cholesterol","score":0.8429999947547913},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9480000138282776},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.8050000071525574},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9789999723434448},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":1.0},{"id":"https://openalex.org/keywords/hdl2-cholesterol","display_name":"HDL2","score":0.7279999852180481},{"id":"https://openalex.org/keywords/plasma-triglycerides","display_name":"plasma triglycerides","score":0.8500000238418579},{"id":"https://openalex.org/keywords/low-fat-diet","display_name":"low-fat diet","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.8250989317893982},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7536791563034058},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6941615343093872},{"id":"https://openalex.org/C2909484148","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Dietary Cholesterol","level":3,"score":0.6219251155853271},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5428234934806824},{"id":"https://openalex.org/C2781321622","wikidata":"https://www.wikidata.org/wiki/Q181409","display_name":"Yolk","level":2,"score":0.5343242287635803},{"id":"https://openalex.org/C3019550498","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Ldl cholesterol","level":3,"score":0.5023839473724365},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.306551992893219},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.1614622175693512}],"mesh":[{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002791","descriptor_name":"Cholesterol, Dietary","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1161/01.atv.10.3.394","doi":"https://doi.org/10.1161/01.atv.10.3.394","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.10.3.394","pdf_url":null,"source":{"id":"https://openalex.org/S4210182225","display_name":"Arteriosclerosis An Official Journal of the American Heart Association Inc","issn_l":"0276-5047","issn":["0276-5047","2330-9180"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis: An Official Journal of the American Heart Association, Inc.","raw_type":"journal-article"},{"id":"pmid:2344298","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2344298","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis (Dallas, Tex.)","raw_type":"Clinical Trial"},{"id":"mag:3144221501","doi":null,"is_oa":true,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/atv81.10.3.2344298","pdf_url":null,"source":{"id":"https://openalex.org/S4210182225","display_name":"Arteriosclerosis An Official Journal of the American Heart Association Inc","issn_l":"0276-5047","issn":["0276-5047","2330-9180"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Arteriosclerosis: An Official Journal of the American Heart Association, Inc.","raw_type":null}],"best_oa_location":{"id":"doi:10.1161/01.atv.10.3.394","doi":"https://doi.org/10.1161/01.atv.10.3.394","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.10.3.394","pdf_url":null,"source":{"id":"https://openalex.org/S4210182225","display_name":"Arteriosclerosis An Official Journal of the American Heart Association Inc","issn_l":"0276-5047","issn":["0276-5047","2330-9180"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis: An Official Journal of the American Heart Association, Inc.","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320386","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07"},{"id":"https://openalex.org/F4320320442","display_name":"National Heart Foundation of Australia","ror":"https://ror.org/039d9wr27"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W45637763","https://openalex.org/W84665409","https://openalex.org/W1515796836","https://openalex.org/W1794858651","https://openalex.org/W1800026128","https://openalex.org/W1873752731","https://openalex.org/W1956068318","https://openalex.org/W1956761008","https://openalex.org/W1964408814","https://openalex.org/W1968691008","https://openalex.org/W1972063776","https://openalex.org/W1997647313","https://openalex.org/W1998613060","https://openalex.org/W2001752924","https://openalex.org/W2015558908","https://openalex.org/W2019616743","https://openalex.org/W2027763516","https://openalex.org/W2042048605","https://openalex.org/W2050550042","https://openalex.org/W2052578635","https://openalex.org/W2054285204","https://openalex.org/W2071115881","https://openalex.org/W2084122060","https://openalex.org/W2103886187","https://openalex.org/W2114807641","https://openalex.org/W2140817144","https://openalex.org/W2149637110","https://openalex.org/W2151481969","https://openalex.org/W2158090220","https://openalex.org/W2164532241","https://openalex.org/W2164850907","https://openalex.org/W2164978843","https://openalex.org/W2165550596","https://openalex.org/W2169904273","https://openalex.org/W2188938709","https://openalex.org/W2256103928","https://openalex.org/W2338597756","https://openalex.org/W2338826018","https://openalex.org/W3023806384"],"related_works":["https://openalex.org/W2252651152","https://openalex.org/W7064995118","https://openalex.org/W2115330628","https://openalex.org/W2338826018","https://openalex.org/W2434545434","https://openalex.org/W7095127337","https://openalex.org/W2165174551","https://openalex.org/W2991296276","https://openalex.org/W1953636111","https://openalex.org/W2982155878"],"abstract_inverted_index":{"A":[0],"group":[1],"of":[2,17,36,107,127,170,186,200,233,239],"56":[3],"hypercholesterolemic":[4],"and":[5,8,72,110,116,198,220],"normocholesterolemic":[6],"men":[7],"women":[9],"were":[10,28,122,137,161,174,184],"given":[11],"approximately":[12,34],"700":[13],"mg":[14],"a":[15,22,30,43,58,73,131,140,149],"day":[16],"egg":[18],"yolk":[19],"cholesterol":[20,49,67,82,98,147,153,172,194,207,216,225],"in":[21,47,62,77,113,145,180,192,205,230],"double-blind,":[23],"crossover":[24],"study":[25],"while":[26],"they":[27],"on":[29,124,148],"background":[31],"diet":[32],"containing":[33],"30%":[35],"energy":[37],"as":[38],"fat.":[39],"Overall":[40],"there":[41],"was":[42],"0.23":[44],"mmol/l":[45,60,75,93,112,188,191,204,219],"rise":[46,61,76],"plasma":[48,146,193],"(3.7%,":[50],"p":[51,69,84],"less":[52,85,99,243],"than":[53,86,100,142,155,173,244],"0.001)":[54],"after":[55],"4":[56],"weeks,":[57],"0.19":[59,190],"low":[63,132,152],"density":[64,79],"lipoprotein":[65,80],"(LDL)":[66],"(4.9%,":[68],"=":[70,196,209],"0.002),":[71],"0.07":[74,92,221],"high":[78],"(HDL)":[81],"(5.4%,":[83],"0.001).":[87],"Plasma":[88],"triglycerides":[89],"fell":[90],"by":[91,139,217],"(5.1%).":[94],"Normocholesterolemic":[95],"individuals":[96,160],"(plasma":[97],"5.2":[101],"mmol/l)":[102],"experienced":[103],"small,":[104],"nonsignificant":[105],"rises":[106,185,199],"0.06,":[108],"0.02,":[109],"0.05":[111],"total,":[114],"LDL,":[115],"HDL":[117,215,240],"cholesterol,":[118],"respectively.":[119],"Hypercholesterolemic":[120],"subjects":[121,136],"classified":[123],"the":[125,168,177,181,231],"basis":[126],"their":[128],"response":[129],"to":[130,163,167,213,237],"fat":[133],"diet.":[134,158],"Diet-sensitive":[135],"defined":[138],"greater":[141],"10%":[143],"fall":[144],"25%":[150],"fat,":[151],"(less":[154],"200":[156],"mg/day)":[157],"These":[159],"found":[162],"be":[164],"more":[165],"responsive":[166],"effect":[169],"dietary":[171,224],"diet-insensitive":[175],"subjects;":[176],"respective":[178],"changes":[179],"two":[182],"groups":[183],"0.36":[187],"versus":[189,202],"(p":[195,208,242],"0.06)":[197],"0.30":[201],"0.15":[203],"LDL":[206],"0.06).":[210],"In":[211],"addition":[212],"elevating":[214],"0.09":[218],"mmol/l,":[222],"respectively,":[223],"also":[226],"produced":[227],"an":[228],"increase":[229],"proportion":[232],"HDL2,":[234],"from":[235],"40%":[236],"44%":[238],"protein":[241],"0.001).(ABSTRACT":[245],"TRUNCATED":[246],"AT":[247],"250":[248],"WORDS)":[249]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}