{"id":"https://openalex.org/W2007562076","doi":"https://doi.org/10.1002/pros.2990140303","title":"Development of monoclonal antibody imaging of metastatic prostatic carcinoma","display_name":"Development of monoclonal antibody imaging of metastatic prostatic carcinoma","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W2007562076","doi":"https://doi.org/10.1002/pros.2990140303","mag":"2007562076","pmid":"https://pubmed.ncbi.nlm.nih.gov/2471962"},"language":"en","primary_location":{"id":"doi:10.1002/pros.2990140303","doi":"https://doi.org/10.1002/pros.2990140303","is_oa":false,"landing_page_url":"https://doi.org/10.1002/pros.2990140303","pdf_url":null,"source":{"id":"https://openalex.org/S197000376","display_name":"The Prostate","issn_l":"0270-4137","issn":["0270-4137","1097-0045"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Prostate","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082791022","display_name":"Frederick J. Meyers","orcid":"https://orcid.org/0000-0002-4456-4647","observed_orcids":["https://orcid.org/0000-0002-4456-4647"]},"institutions":[{"id":"https://openalex.org/I1288198617","display_name":"American Cancer Society","ror":"https://ror.org/02e463172","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1288198617"]},{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frederick J. Meyers","raw_affiliation_strings":["Department of Internal Medicine, Davis Medical Center, University of California, Sacramento","Department of Internal Medicine, Division of Hematology/Oncology, Davis Medical Center, University of California, Sacramento, California","Dr. Meyers is a recipient of an American Cancer Society Faculty Career Development Award"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Davis Medical Center, University of California, Sacramento","institution_ids":["https://openalex.org/I4210160527"]},{"raw_affiliation_string":"Department of Internal Medicine, Division of Hematology/Oncology, Davis Medical Center, University of California, Sacramento, California","institution_ids":["https://openalex.org/I4210160527"]},{"raw_affiliation_string":"Dr. Meyers is a recipient of an American Cancer Society Faculty Career Development Award","institution_ids":["https://openalex.org/I1288198617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111607459","display_name":"Sally J. DeNardo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sally J. Denardo","raw_affiliation_strings":["Department of Internal Medicine, Division of Hematology/Oncology, Davis Medical Center, University of California, Sacramento, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Division of Hematology/Oncology, Davis Medical Center, University of California, Sacramento, California","institution_ids":["https://openalex.org/I4210160527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112017400","display_name":"Daniel J. Macey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Macey","raw_affiliation_strings":["Department of Internal Medicine, Division of Hematology/Oncology, Davis Medical Center, University of California, Sacramento, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Division of Hematology/Oncology, Davis Medical Center, University of California, Sacramento, California","institution_ids":["https://openalex.org/I4210160527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014023814","display_name":"Ralph Devere White","orcid":"https://orcid.org/0000-0002-2170-626X","observed_orcids":["https://orcid.org/0000-0002-2170-626X"]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ralph Devere White","raw_affiliation_strings":["Department of Urology, Davis Medical Center, University of California, Sacramento, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Davis Medical Center, University of California, Sacramento, California","institution_ids":["https://openalex.org/I4210160527"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100695589","display_name":"MICHAEL W. UNGER","orcid":"https://orcid.org/0000-0002-5712-2768","observed_orcids":["https://orcid.org/0000-0002-5712-2768"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Unger","raw_affiliation_strings":["Hybritech, San Diego, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hybritech, San Diego, California","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5082791022"],"corresponding_institution_ids":["https://openalex.org/I1288198617","https://openalex.org/I4210160527"],"apc_list":{"value":4600,"currency":"USD","value_usd":4600},"apc_paid":null,"fwci":2.5215,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.87929735,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"14","issue":"3","first_page":"209","last_page":"220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/111in","display_name":"indium-111","score":0.7820000052452087},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.9750000238418579},{"id":"https://openalex.org/keywords/metastatic-prostatic-carcinoma","display_name":"metastatic prostatic carcinoma","score":0.9010000228881836},{"id":"https://openalex.org/keywords/technetium-bone-scan","display_name":"technetium bone scan","score":0.6830000281333923},{"id":"https://openalex.org/keywords/radiolabeled-antibodies","display_name":"radiolabeled antibodies","score":0.6949999928474426},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.921999990940094},{"id":"https://openalex.org/keywords/tumor-staging","display_name":"tumor staging","score":0.8550000190734863},{"id":"https://openalex.org/keywords/therapeutic-adjuvant","display_name":"therapeutic adjuvant","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.8167439103126526},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7077685594558716},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5889461636543274},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.5595561265945435},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.5586051940917969},{"id":"https://openalex.org/C2777064799","wikidata":"https://www.wikidata.org/wiki/Q1660202","display_name":"Immunoscintigraphy","level":5,"score":0.5040518045425415},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.49663692712783813},{"id":"https://openalex.org/C2993388676","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate carcinoma","level":4,"score":0.46676111221313477},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.45563948154449463},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.44621968269348145},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.43649959564208984},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.43141481280326843},{"id":"https://openalex.org/C2776146153","wikidata":"https://www.wikidata.org/wiki/Q7281276","display_name":"Radioimmunotherapy","level":4,"score":0.4246044456958771},{"id":"https://openalex.org/C2778755798","wikidata":"https://www.wikidata.org/wiki/Q3542027","display_name":"Epithelioma","level":3,"score":0.4202668368816376},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3272867202758789},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.30547958612442017},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2923705577850342},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.25640159845352173},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21793657541275024}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000912","descriptor_name":"Antibodies, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011467","descriptor_name":"Prostate","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011467","descriptor_name":"Prostate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011877","descriptor_name":"Radionuclide Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/pros.2990140303","doi":"https://doi.org/10.1002/pros.2990140303","is_oa":false,"landing_page_url":"https://doi.org/10.1002/pros.2990140303","pdf_url":null,"source":{"id":"https://openalex.org/S197000376","display_name":"The Prostate","issn_l":"0270-4137","issn":["0270-4137","1097-0045"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Prostate","raw_type":"journal-article"},{"id":"pmid:2471962","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2471962","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Prostate","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W145446261","https://openalex.org/W1210954471","https://openalex.org/W1224513713","https://openalex.org/W1784267169","https://openalex.org/W1903690808","https://openalex.org/W2029608296","https://openalex.org/W2061778683","https://openalex.org/W2072268804","https://openalex.org/W2073656236","https://openalex.org/W2158122865","https://openalex.org/W2225416664","https://openalex.org/W2276852356","https://openalex.org/W2330292521","https://openalex.org/W2731668663","https://openalex.org/W6670005920"],"related_works":["https://openalex.org/W2035068824","https://openalex.org/W279593907","https://openalex.org/W2060180099","https://openalex.org/W2011484282","https://openalex.org/W2397546132","https://openalex.org/W2733530621","https://openalex.org/W2087587115","https://openalex.org/W2076134978","https://openalex.org/W2015329310","https://openalex.org/W2049047795"],"abstract_inverted_index":{"Indium-111-labeled":[0],"monoclonal":[1,21],"antibody":[2,22,53,68],"directed":[3],"against":[4],"prostate-specific":[5],"antigen":[6],"was":[7,24],"injected":[8],"into":[9],"ten":[10],"patients":[11],"with":[12,17],"known":[13],"prostatic":[14],"carcinoma,":[15],"nine":[16],"metastatic":[18],"disease.":[19],"The":[20,43],"scan":[23],"compared":[25],"to":[26,36,40],"the":[27,51],"standard":[28],"technetium":[29],"bone":[30],"scan,":[31],"and":[32,39,48,75],"both":[33],"were":[34,54],"correlated":[35],"clinical":[37],"status":[38],"2-year":[41],"follow-up.":[42],"ratio":[44],"of":[45,50,65],"target-to-nontarget":[46],"activity":[47],"pharmacokinetics":[49],"radiolabeled":[52,67],"determined.":[55],"Based":[56],"on":[57],"these":[58],"findings":[59],"we":[60],"are":[61],"hopeful":[62],"that":[63],"modifications":[64],"this":[66],"approach":[69],"may":[70,76],"be":[71,77],"used":[72],"for":[73],"staging":[74],"developed":[78],"as":[79],"a":[80],"therapeutic":[81],"adjuvant.":[82]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}