{"id":"https://openalex.org/W2007479557","doi":"https://doi.org/10.1016/0049-3848(79)90218-4","title":"Visualization of VIII:C-like material in a CRM negative hemophiliac","display_name":"Visualization of VIII:C-like material in a CRM negative hemophiliac","publication_year":1979,"publication_date":"1979-01-01","ids":{"openalex":"https://openalex.org/W2007479557","doi":"https://doi.org/10.1016/0049-3848(79)90218-4","mag":"2007479557","pmid":"https://pubmed.ncbi.nlm.nih.gov/524319"},"language":"en","primary_location":{"id":"doi:10.1016/0049-3848(79)90218-4","doi":"https://doi.org/10.1016/0049-3848(79)90218-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0049-3848(79)90218-4","pdf_url":null,"source":{"id":"https://openalex.org/S134546602","display_name":"Thrombosis Research","issn_l":"0049-3848","issn":["0049-3848","1879-2472"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063004972","display_name":"G. A. Rock","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"G.A. Rock","raw_affiliation_strings":["Faculty of Medicine, University of Ottawa Ottawa, K1N 6N5, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Ottawa Ottawa, K1N 6N5, Canada","institution_ids":["https://openalex.org/I153718931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112806855","display_name":"Douglas S. Palmer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51917231","display_name":"Canadian Red Cross Society","ror":"https://ror.org/01t0p7s78","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I51917231"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D.S. Palmer","raw_affiliation_strings":["The Canadian Red Cross Blood Transfusion Service Ottawa, K1S 3E2, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Canadian Red Cross Blood Transfusion Service Ottawa, K1S 3E2, Canada","institution_ids":["https://openalex.org/I51917231"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058787697","display_name":"William H. Cruickshank","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51917231","display_name":"Canadian Red Cross Society","ror":"https://ror.org/01t0p7s78","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I51917231"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"W.H. Cruickshank","raw_affiliation_strings":["The Canadian Red Cross Blood Transfusion Service Ottawa, K1S 3E2, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Canadian Red Cross Blood Transfusion Service Ottawa, K1S 3E2, Canada","institution_ids":["https://openalex.org/I51917231"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4080,"currency":"USD","value_usd":4080},"apc_paid":null,"fwci":0.7192,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.69109212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"5-6","first_page":"747","last_page":"757"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemophilia-b","display_name":"hemophilia B","score":0.43799999356269836},{"id":"https://openalex.org/keywords/isoelectric-focusing","display_name":"isoelectric focusing","score":0.6669999957084656},{"id":"https://openalex.org/keywords/sds-polyacrylamide-gel-electrophoresis","display_name":"SDS-polyacrylamide gel electrophoresis","score":0.9300000071525574},{"id":"https://openalex.org/keywords/dtt-reduction","display_name":"DTT reduction","score":0.6079999804496765},{"id":"https://openalex.org/keywords/column-chromatography","display_name":"column chromatography","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7547159194946289},{"id":"https://openalex.org/C73826308","wikidata":"https://www.wikidata.org/wiki/Q684907","display_name":"Elution","level":2,"score":0.6451781988143921},{"id":"https://openalex.org/C96294017","wikidata":"https://www.wikidata.org/wiki/Q308708","display_name":"Isoelectric point","level":3,"score":0.5984231233596802},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5217241048812866},{"id":"https://openalex.org/C101660505","wikidata":"https://www.wikidata.org/wiki/Q898301","display_name":"Polyacrylamide gel electrophoresis","level":3,"score":0.4794403612613678},{"id":"https://openalex.org/C50476208","wikidata":"https://www.wikidata.org/wiki/Q898861","display_name":"Isoelectric focusing","level":3,"score":0.46091607213020325},{"id":"https://openalex.org/C116084860","wikidata":"https://www.wikidata.org/wiki/Q48255","display_name":"Gel electrophoresis","level":2,"score":0.4251026511192322},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35111308097839355},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34843921661376953},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11609753966331482},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05976450443267822}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002850","descriptor_name":"Chromatography, Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004229","descriptor_name":"Dithiothreitol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005169","descriptor_name":"Factor VIII","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005169","descriptor_name":"Factor VIII","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D006467","descriptor_name":"Hemophilia A","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006467","descriptor_name":"Hemophilia A","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007525","descriptor_name":"Isoelectric Focusing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0049-3848(79)90218-4","doi":"https://doi.org/10.1016/0049-3848(79)90218-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0049-3848(79)90218-4","pdf_url":null,"source":{"id":"https://openalex.org/S134546602","display_name":"Thrombosis Research","issn_l":"0049-3848","issn":["0049-3848","1879-2472"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis Research","raw_type":"journal-article"},{"id":"pmid:524319","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/524319","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1599875694","https://openalex.org/W1976127863","https://openalex.org/W1977275789","https://openalex.org/W1996314665","https://openalex.org/W1997590790","https://openalex.org/W2013963813","https://openalex.org/W2051837386","https://openalex.org/W2061204089","https://openalex.org/W2073879684","https://openalex.org/W2137942218","https://openalex.org/W2158841112","https://openalex.org/W2295212550","https://openalex.org/W2346064701","https://openalex.org/W2408686604","https://openalex.org/W2410654340","https://openalex.org/W2412247503","https://openalex.org/W2946608179"],"related_works":["https://openalex.org/W2030652671","https://openalex.org/W2946748528","https://openalex.org/W2011058698","https://openalex.org/W1977275789","https://openalex.org/W2946608179","https://openalex.org/W2082708810","https://openalex.org/W2078920603","https://openalex.org/W2071978314","https://openalex.org/W2064755249","https://openalex.org/W2344361000"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}