{"id":"https://openalex.org/W2007478145","doi":"https://doi.org/10.1007/s10549-012-2068-7","title":"Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor","display_name":"Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor","publication_year":2012,"publication_date":"2012-04-25","ids":{"openalex":"https://openalex.org/W2007478145","doi":"https://doi.org/10.1007/s10549-012-2068-7","mag":"2007478145","pmid":"https://pubmed.ncbi.nlm.nih.gov/22535017"},"language":"en","primary_location":{"id":"doi:10.1007/s10549-012-2068-7","doi":"https://doi.org/10.1007/s10549-012-2068-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10549-012-2068-7","pdf_url":null,"source":{"id":"https://openalex.org/S142211178","display_name":"Breast Cancer Research and Treatment","issn_l":"0167-6806","issn":["0167-6806","1573-7217"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast Cancer Research and Treatment","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040386046","display_name":"Elizabeth J. Iorns","orcid":"https://orcid.org/0000-0002-5515-1258","observed_orcids":["https://orcid.org/0000-0002-5515-1258"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elizabeth Iorns","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL 33136, USA. eiorns@med.miami.edu","University of Miami,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL 33136, USA. eiorns@med.miami.edu","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami,","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024855901","display_name":"Toby M. Ward","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Toby M. Ward","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","University of Miami,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami,","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109286122","display_name":"Sonja Dean","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sonja Dean","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","University of Miami,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami,","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112481423","display_name":"Anna Maria Jegg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Jegg","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","University of Miami,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami,","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030234836","display_name":"Dafydd G. Thomas","orcid":"https://orcid.org/0000-0002-0379-7460","observed_orcids":["https://orcid.org/0000-0002-0379-7460"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dafydd Thomas","raw_affiliation_strings":["Department of Pathology, University of Michigan Cancer Center, Ann Arbor, MI, 48109, USA","Department of Pathology, University of Michigan Cancer Center, Ann Arbor, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Michigan Cancer Center, Ann Arbor, MI, 48109, USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4390039285"]},{"raw_affiliation_string":"Department of Pathology, University of Michigan Cancer Center, Ann Arbor, USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4390039285"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009530521","display_name":"Nirupa Murugaesu","orcid":"https://orcid.org/0000-0002-5005-7908","observed_orcids":["https://orcid.org/0000-0002-5005-7908"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nirupa Murugaesu","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061470053","display_name":"David Sims","orcid":"https://orcid.org/0000-0001-8960-8335","observed_orcids":["https://orcid.org/0000-0001-8960-8335"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Sims","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063297467","display_name":"Costas Mitsopoulos","orcid":"https://orcid.org/0000-0002-9116-5921","observed_orcids":["https://orcid.org/0000-0002-9116-5921"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Costas Mitsopoulos","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091516461","display_name":"Kerry Fenwick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kerry Fenwick","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033008477","display_name":"Iwanka Kozarewa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Iwanka Kozarewa","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001696912","display_name":"Cristina Naceur\u2010Lombardelli","orcid":"https://orcid.org/0000-0002-7097-0307","observed_orcids":["https://orcid.org/0000-0002-7097-0307"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Cristina Naceur-Lombarelli","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022425237","display_name":"Marketa Zvelebil","orcid":"https://orcid.org/0000-0001-8018-5591","observed_orcids":["https://orcid.org/0000-0001-8018-5591"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marketa Zvelebil","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061098872","display_name":"Clare M. Isacke","orcid":"https://orcid.org/0000-0002-9222-3345","observed_orcids":["https://orcid.org/0000-0002-9222-3345"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Clare M. Isacke","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088018441","display_name":"Christopher J. Lord","orcid":"https://orcid.org/0000-0002-3226-0515","observed_orcids":["https://orcid.org/0000-0002-3226-0515"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christopher J. Lord","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058973407","display_name":"Alan Ashworth","orcid":"https://orcid.org/0000-0003-1446-7878","observed_orcids":["https://orcid.org/0000-0003-1446-7878","https://orcid.org/0009-0008-8974-2233"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alan Ashworth","raw_affiliation_strings":["The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK","institution_ids":["https://openalex.org/I142947616"]},{"raw_affiliation_string":"The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075302851","display_name":"H. James Hnatyszyn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. James Hnatyszyn","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","University of Miami,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami,","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030502460","display_name":"Mark Daniel Pegram","orcid":"https://orcid.org/0000-0002-9743-8118","observed_orcids":["https://orcid.org/0000-0002-9743-8118"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Pegram","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","University of Miami,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami,","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028539104","display_name":"Marc E. Lippman","orcid":"https://orcid.org/0000-0001-5280-4084","observed_orcids":["https://orcid.org/0000-0001-5280-4084"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marc Lippman","raw_affiliation_strings":["Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","Department of Medicine, School of Medicine, University of Miami, Miami, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, 1501 NW 10th Ave (BRB 701), Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Medicine, School of Medicine, University of Miami, Miami, USA","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5040386046"],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":2.6984,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.90594825,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"135","issue":"1","first_page":"79","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.576200008392334,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.576200008392334,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.09989999979734421,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":0.0869000032544136,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lifr","display_name":"LIFR","score":0.984000027179718},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.9160000085830688},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9909999966621399},{"id":"https://openalex.org/keywords/tp53","display_name":"TP53","score":0.7570000290870667},{"id":"https://openalex.org/keywords/medical-nutrition-therapy","display_name":"medical nutrition therapy","score":0.9850000143051147},{"id":"https://openalex.org/keywords/oncogene-identification","display_name":"oncogene identification","score":0.6430000066757202},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.7119021415710449},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6864203214645386},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.6834039688110352},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.6676914691925049},{"id":"https://openalex.org/C2778264664","wikidata":"https://www.wikidata.org/wiki/Q422445","display_name":"Tumor suppressor gene","level":4,"score":0.5966247916221619},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5622220039367676},{"id":"https://openalex.org/C106825092","wikidata":"https://www.wikidata.org/wiki/Q14914453","display_name":"Leukemia inhibitory factor receptor","level":5,"score":0.546870231628418},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5171446204185486},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.484596848487854},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4441157579421997},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35152125358581543},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.22780737280845642},{"id":"https://openalex.org/C27284151","wikidata":"https://www.wikidata.org/wiki/Q6534502","display_name":"Leukemia inhibitory factor","level":4,"score":0.12257236242294312},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016147","descriptor_name":"Genes, Tumor Suppressor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016158","descriptor_name":"Genes, p53","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051778","descriptor_name":"Basic Helix-Loop-Helix Leucine Zipper Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D053680","descriptor_name":"Leukemia Inhibitory Factor Receptor alpha Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10549-012-2068-7","doi":"https://doi.org/10.1007/s10549-012-2068-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10549-012-2068-7","pdf_url":null,"source":{"id":"https://openalex.org/S142211178","display_name":"Breast Cancer Research and Treatment","issn_l":"0167-6806","issn":["0167-6806","1573-7217"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast Cancer Research and Treatment","raw_type":"journal-article"},{"id":"pmid:22535017","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22535017","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast cancer research and treatment","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1395384","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1395384/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BREAST CANCER RESEARCH AND TREATMENT , 135 (1) pp. 79-91. (2012)","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320338273","display_name":"Congressionally Directed Medical Research Programs","ror":"https://ror.org/03g2zjp07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1989316220","https://openalex.org/W2005542290","https://openalex.org/W2013689460","https://openalex.org/W2019267973","https://openalex.org/W2023568503","https://openalex.org/W2027345413","https://openalex.org/W2028395883","https://openalex.org/W2029175285","https://openalex.org/W2034269086","https://openalex.org/W2039394834","https://openalex.org/W2041783360","https://openalex.org/W2051886524","https://openalex.org/W2070544303","https://openalex.org/W2074425666","https://openalex.org/W2083205626","https://openalex.org/W2087099947","https://openalex.org/W2092620749","https://openalex.org/W2097255042","https://openalex.org/W2099203843","https://openalex.org/W2100327770","https://openalex.org/W2105912300","https://openalex.org/W2109303707","https://openalex.org/W2121665844","https://openalex.org/W2131994307","https://openalex.org/W2136029031","https://openalex.org/W2157840751","https://openalex.org/W2159993068","https://openalex.org/W2162298538","https://openalex.org/W2167005345","https://openalex.org/W2167090289","https://openalex.org/W2318605753","https://openalex.org/W2329648702","https://openalex.org/W2419252882"],"related_works":["https://openalex.org/W228044437","https://openalex.org/W4232113409","https://openalex.org/W2084879212","https://openalex.org/W2013689460","https://openalex.org/W2399313625","https://openalex.org/W2167005345","https://openalex.org/W3009870983","https://openalex.org/W2320742570","https://openalex.org/W1511465100","https://openalex.org/W2053181131"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}