{"id":"https://openalex.org/W2007474550","doi":"https://doi.org/10.1073/pnas.1114198109","title":"Novelty exposure overcomes foot shock-induced spatial-memory impairment by processes of synaptic-tagging in rats","display_name":"Novelty exposure overcomes foot shock-induced spatial-memory impairment by processes of synaptic-tagging in rats","publication_year":2012,"publication_date":"2012-01-03","ids":{"openalex":"https://openalex.org/W2007474550","doi":"https://doi.org/10.1073/pnas.1114198109","mag":"2007474550","pmid":"https://pubmed.ncbi.nlm.nih.gov/22215603","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3271890"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.1114198109","doi":"https://doi.org/10.1073/pnas.1114198109","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.1114198109","pdf_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.1114198109","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.1114198109","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056473813","display_name":"William Almaguer\u2010Melian","orcid":"https://orcid.org/0000-0001-7920-9568","observed_orcids":["https://orcid.org/0000-0001-7920-9568"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William Almaguer-Melian","raw_affiliation_strings":["Departamento de Neurofisiolog\u00eda Experimental"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Neurofisiolog\u00eda Experimental","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050139753","display_name":"Jorge A. Bergado","orcid":"https://orcid.org/0000-0002-7239-5182","observed_orcids":["https://orcid.org/0000-0002-7239-5182"]},"institutions":[{"id":"https://openalex.org/I4210149409","display_name":"International Center of Neurologic Restoration","ror":"https://ror.org/04770s302","country_code":"CU","type":"facility","lineage":["https://openalex.org/I4210149409"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Jorge Bergado-Rosado","raw_affiliation_strings":["Departamento de Neurofisiolog\u00eda Experimental","Centro Internacional de Restauracion Neurologica"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Neurofisiolog\u00eda Experimental","institution_ids":[]},{"raw_affiliation_string":"Centro Internacional de Restauracion Neurologica","institution_ids":["https://openalex.org/I4210149409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056268936","display_name":"Nancy Pav\u00f3n Fuentes","orcid":"https://orcid.org/0000-0003-0998-8601","observed_orcids":["https://orcid.org/0000-0003-0998-8601"]},"institutions":[{"id":"https://openalex.org/I4210149409","display_name":"International Center of Neurologic Restoration","ror":"https://ror.org/04770s302","country_code":"CU","type":"facility","lineage":["https://openalex.org/I4210149409"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Nancy Pav\u00f3n-Fuentes","raw_affiliation_strings":["Departamento de Neuroinmunolog\u00eda, and","Centro Internacional de Restauracion Neurologica"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Neuroinmunolog\u00eda, and","institution_ids":[]},{"raw_affiliation_string":"Centro Internacional de Restauracion Neurologica","institution_ids":["https://openalex.org/I4210149409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089638227","display_name":"Esteban Alberti\u2010Amador","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149409","display_name":"International Center of Neurologic Restoration","ror":"https://ror.org/04770s302","country_code":"CU","type":"facility","lineage":["https://openalex.org/I4210149409"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Esteban Alberti-Amador","raw_affiliation_strings":["Departamento de Neurobiolog\u00eda, Centro Internacional de Restauraci\u00f3n Neurol\u00f3gica, Havana 11300, Cuba;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Neurobiolog\u00eda, Centro Internacional de Restauraci\u00f3n Neurol\u00f3gica, Havana 11300, Cuba;","institution_ids":["https://openalex.org/I4210149409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046814548","display_name":"Daymara Mercer\u00f3n\u2010Mart\u00ednez","orcid":"https://orcid.org/0000-0003-1218-3433","observed_orcids":["https://orcid.org/0000-0003-1218-3433"]},"institutions":[{"id":"https://openalex.org/I2802407485","display_name":"Cuban Neuroscience Center","ror":"https://ror.org/00rk1k743","country_code":"CU","type":"facility","lineage":["https://openalex.org/I2802407485"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Daymara Mercer\u00f3n-Mart\u00ednez","raw_affiliation_strings":["Dpto de Neuroestimulaci\u00f3n, Centro de Neurociencias de Cuba, Havana 11300, Cuba;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto de Neuroestimulaci\u00f3n, Centro de Neurociencias de Cuba, Havana 11300, Cuba;","institution_ids":["https://openalex.org/I2802407485"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111768357","display_name":"Julietta Uta Frey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]},{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Julietta U. Frey","raw_affiliation_strings":["Department of Neurophysiology, Leibniz-Institute for Neurobiology, Magdeburg D-39118, Germany","Medical Faculty, Otto-von-Guericke University, Magdeburg D-39120, Germany; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurophysiology, Leibniz-Institute for Neurobiology, Magdeburg D-39118, Germany","institution_ids":["https://openalex.org/I96578850"]},{"raw_affiliation_string":"Medical Faculty, Otto-von-Guericke University, Magdeburg D-39120, Germany; and","institution_ids":["https://openalex.org/I95793202"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5111768357"],"corresponding_institution_ids":["https://openalex.org/I95793202","https://openalex.org/I96578850"],"apc_list":null,"apc_paid":null,"fwci":3.7065,"has_fulltext":false,"cited_by_count":73,"citation_normalized_percentile":{"value":0.93457246,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"109","issue":"3","first_page":"953","last_page":"958"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10918","display_name":"Memory Processes and Influences","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/novelty-exposure","display_name":"novelty exposure","score":0.9440000057220459},{"id":"https://openalex.org/keywords/foot-shock-stress","display_name":"footshock stress","score":0.6740000247955322},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.6259999871253967},{"id":"https://openalex.org/keywords/memory-consolidation","display_name":"memory consolidation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/long-term-memory","display_name":"long-term memory","score":0.6959999799728394},{"id":"https://openalex.org/keywords/short-term-memory","display_name":"short-term memory","score":0.8920000195503235},{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":0.7210000157356262},{"id":"https://openalex.org/keywords/arc","display_name":"Arc","score":0.9269999861717224},{"id":"https://openalex.org/keywords/anisomycin","display_name":"anisomycin","score":0.7689999938011169},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.7689999938011169},{"id":"https://openalex.org/keywords/protein-synthesis","display_name":"protein synthesis","score":0.503000020980835},{"id":"https://openalex.org/keywords/water-maze","display_name":"water maze","score":0.625}],"concepts":[{"id":"https://openalex.org/C48455012","wikidata":"https://www.wikidata.org/wiki/Q2892593","display_name":"Memory consolidation","level":3,"score":0.8032974004745483},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6627646684646606},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.6157936453819275},{"id":"https://openalex.org/C2778738651","wikidata":"https://www.wikidata.org/wiki/Q16546687","display_name":"Novelty","level":2,"score":0.6056838035583496},{"id":"https://openalex.org/C2778073123","wikidata":"https://www.wikidata.org/wiki/Q378498","display_name":"Anisomycin","level":3,"score":0.5666373372077942},{"id":"https://openalex.org/C24590219","wikidata":"https://www.wikidata.org/wiki/Q18601","display_name":"Long-term memory","level":3,"score":0.5085731744766235},{"id":"https://openalex.org/C194973443","wikidata":"https://www.wikidata.org/wiki/Q1420291","display_name":"Metaplasticity","level":4,"score":0.4213985800743103},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.3804659843444824},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.34346452355384827},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22053292393684387},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.07306322455406189},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.06870147585868835},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004597","descriptor_name":"Electroshock","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005106","descriptor_name":"Exploratory Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005528","descriptor_name":"Foot","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008569","descriptor_name":"Memory Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.1114198109","doi":"https://doi.org/10.1073/pnas.1114198109","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.1114198109","pdf_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.1114198109","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2401409","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3271890","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:22215603","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22215603","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3271890","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3271890/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1073/pnas.1114198109","doi":"https://doi.org/10.1073/pnas.1114198109","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.1114198109","pdf_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.1114198109","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2007474550.pdf"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1488313827","https://openalex.org/W1571281589","https://openalex.org/W1591973843","https://openalex.org/W1607671357","https://openalex.org/W1724698019","https://openalex.org/W1825797577","https://openalex.org/W1867703876","https://openalex.org/W1966399026","https://openalex.org/W1968633122","https://openalex.org/W1974461221","https://openalex.org/W1987178596","https://openalex.org/W1996599661","https://openalex.org/W2002140212","https://openalex.org/W2005901591","https://openalex.org/W2010911467","https://openalex.org/W2011882079","https://openalex.org/W2013185658","https://openalex.org/W2020969390","https://openalex.org/W2021485981","https://openalex.org/W2024367856","https://openalex.org/W2025801062","https://openalex.org/W2029687467","https://openalex.org/W2032691579","https://openalex.org/W2035139662","https://openalex.org/W2041915527","https://openalex.org/W2043610928","https://openalex.org/W2044183295","https://openalex.org/W2046909406","https://openalex.org/W2050663258","https://openalex.org/W2051473177","https://openalex.org/W2055391909","https://openalex.org/W2056270533","https://openalex.org/W2058053468","https://openalex.org/W2062915676","https://openalex.org/W2070250157","https://openalex.org/W2079472132","https://openalex.org/W2079911317","https://openalex.org/W2087724123","https://openalex.org/W2089977417","https://openalex.org/W2091667609","https://openalex.org/W2092765329","https://openalex.org/W2093359244","https://openalex.org/W2095538139","https://openalex.org/W2121007598","https://openalex.org/W2146205533","https://openalex.org/W2162052978","https://openalex.org/W2167423431","https://openalex.org/W2168660234","https://openalex.org/W2169821305","https://openalex.org/W2171569424","https://openalex.org/W2439097133"],"related_works":["https://openalex.org/W2070250157","https://openalex.org/W2041915527","https://openalex.org/W1988465033","https://openalex.org/W2146205533","https://openalex.org/W3170405197","https://openalex.org/W2394729688","https://openalex.org/W3040205446","https://openalex.org/W2791276543","https://openalex.org/W6987531659","https://openalex.org/W3150875932"],"abstract_inverted_index":{"Novelty":[0,70],"processing":[1],"can":[2,105],"transform":[3,61],"short-term":[4,28,63,187],"into":[5,66],"long-term":[6,68,184,248],"memory.":[7,99,249],"We":[8,143],"propose":[9],"that":[10,181,229],"this":[11],"memory-reinforcing":[12],"effect":[13,195,223],"of":[14,77,127,211],"novelty":[15,204],"could":[16],"be":[17],"explained":[18],"by":[19,32,94,130,160,226,235],"mechanisms":[20],"outlined":[21],"in":[22,73,189],"the":[23,53,75,95,125,134,140,190,207,212,243],"\"synaptic":[24],"tagging":[25],"hypothesis.\"":[26],"Initial":[27],"memory":[29,128,188,197,209],"is":[30,71],"sustained":[31],"a":[33,62,67,149,161],"transient":[34],"plasticity":[35],"change":[36,65],"at":[37],"activated":[38],"synapses":[39,231],"and":[40,51,109,132,201,215,218,237],"sets":[41],"synaptic":[42,64,110],"tags.":[43],"These":[44],"tags":[45],"are":[46,58,91,121],"later":[47],"able":[48,122,240],"to":[49,60,102,117,123,153,241],"capture":[50,242],"process":[52],"plasticity-related":[54],"proteins":[55],"(PRPs),":[56],"which":[57,90],"required":[59],"one.":[69],"involved":[72],"inducing":[74],"synthesis":[76],"PRPs":[78,120],"[Moncada":[79],"D,":[80],"et":[81],"al.":[82],"(2011)":[83],"Proc":[84],"Natl":[85],"Acad":[86],"Sci":[87],"USA":[88],"108:12937-12936],":[89],"then":[92],"captured":[93],"tagged":[96],"synapses,":[97],"consolidating":[98],"In":[100],"contrast":[101],"novelty,":[103],"stress":[104,131],"impair":[106],"learning,":[107],"memory,":[108],"plasticity.":[111],"Here,":[112],"we":[113],"address":[114],"questions":[115],"as":[116,148],"whether":[118],"novelty-induced":[119,244],"prevent":[124],"loss":[126,210],"caused":[129],"if":[133],"latter":[135],"would":[136],"not":[137,186,233],"interact":[138],"with":[139],"tag-setting":[141],"process.":[142],"used":[144],"water-maze":[145],"(WM)":[146],"training":[147],"spatial":[150,213],"learning":[151],"paradigm":[152],"test":[154],"our":[155],"hypothesis.":[156],"Stress":[157],"was":[158,199,224],"induced":[159],"strong":[162],"foot":[163],"shock":[164],"(FS;":[165],"5":[166,173],"\u00d7":[167],"1":[168],"mA,":[169],"2":[170],"s)":[171],"applied":[172],"min":[174],"after":[175],"WM":[176,191],"training.":[177],"Our":[178],"data":[179],"show":[180],"FS":[182,236],"reduced":[183],"but":[185],"paradigm.":[192],"This":[193,221],"negative":[194],"on":[196],"consolidation":[198],"time-":[200],"training-dependent.":[202],"Interestingly,":[203],"exposure":[205],"prevented":[206],"stress-induced":[208],"task":[214],"increased":[216],"BDNF":[217],"Arc":[219],"expression.":[220],"rescuing":[222],"blocked":[225],"anisomycin,":[227],"suggesting":[228],"WM-tagged":[230],"were":[232,238],"reset":[234],"thus":[239],"PRPs,":[245],"re-establishing":[246],"FS-impaired":[247]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}