{"id":"https://openalex.org/W2007405527","doi":"https://doi.org/10.1902/annals.1998.3.1.262","title":"Implications of Oral Infections on Systemic Diseases in the Institutionalized Elderly With a Special Focus on Pneumonia","display_name":"Implications of Oral Infections on Systemic Diseases in the Institutionalized Elderly With a Special Focus on Pneumonia","publication_year":1998,"publication_date":"1998-07-01","ids":{"openalex":"https://openalex.org/W2007405527","doi":"https://doi.org/10.1902/annals.1998.3.1.262","mag":"2007405527","pmid":"https://pubmed.ncbi.nlm.nih.gov/9722710"},"language":"en","primary_location":{"id":"doi:10.1902/annals.1998.3.1.262","doi":"https://doi.org/10.1902/annals.1998.3.1.262","is_oa":false,"landing_page_url":"https://doi.org/10.1902/annals.1998.3.1.262","pdf_url":null,"source":{"id":"https://openalex.org/S144469688","display_name":"Annals of Periodontology","issn_l":"1553-0841","issn":["1553-0841","2162-5131"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Periodontology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049460440","display_name":"Hardy Limeback","orcid":"https://orcid.org/0000-0001-5453-7709","observed_orcids":["https://orcid.org/0000-0001-5453-7709"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Hardy Limeback","raw_affiliation_strings":["Faculty of Dentistry, University of Toronto, Canada. hlimeback@dental.utoronto.ca","Faculty of Dentistry, University of Toronto (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, University of Toronto, Canada. hlimeback@dental.utoronto.ca","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Faculty of Dentistry, University of Toronto (Canada)","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049460440"],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":null,"apc_paid":null,"fwci":6.6115,"has_fulltext":false,"cited_by_count":100,"citation_normalized_percentile":{"value":0.97242842,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"3","issue":"1","first_page":"262","last_page":"275"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.7074999809265137,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.7074999809265137,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11681","display_name":"Nosocomial Infections in ICU","score":0.22599999606609344,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.015399999916553497,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-infection","display_name":"oral infection","score":0.9810000061988831},{"id":"https://openalex.org/keywords/systemic-infection","display_name":"systemic infection","score":0.4690000116825104},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.6850000023841858},{"id":"https://openalex.org/keywords/institutionalized-elderly","display_name":"institutionalized elderly","score":0.9810000061988831},{"id":"https://openalex.org/keywords/nursing-homes","display_name":"nursing homes","score":0.7369999885559082},{"id":"https://openalex.org/keywords/aspiration","display_name":"aspiration","score":0.5680000185966492},{"id":"https://openalex.org/keywords/oropharyngeal-colonization","display_name":"oropharyngeal colonization","score":0.8169999718666077},{"id":"https://openalex.org/keywords/dental-plaque","display_name":"dental plaque","score":0.8050000071525574},{"id":"https://openalex.org/keywords/periodontal-disease","display_name":"periodontal disease","score":0.9879999756813049},{"id":"https://openalex.org/keywords/oral-hygiene","display_name":"oral hygiene","score":0.9580000042915344},{"id":"https://openalex.org/keywords/selective-decontamination-of-the-digestive-tract","display_name":"selective decontamination of the digestive tract","score":0.7369999885559082},{"id":"https://openalex.org/keywords/hospital-acquired-pneumonia","display_name":"nosocomial pneumonia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/postoperative-pneumonia","display_name":"postoperative pneumonia","score":0.5950000286102295},{"id":"https://openalex.org/keywords/chlorhexidine","display_name":"chlorhexidine","score":0.7570000290870667},{"id":"https://openalex.org/keywords/hematogenous-spread","display_name":"hematogenous spread","score":0.6259999871253967},{"id":"https://openalex.org/keywords/host-defense","display_name":"host defense","score":0.32899999618530273}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9193096160888672},{"id":"https://openalex.org/C515851188","wikidata":"https://www.wikidata.org/wiki/Q13445028","display_name":"Oral hygiene","level":2,"score":0.7798593044281006},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.7189099788665771},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.7025983929634094},{"id":"https://openalex.org/C2781338923","wikidata":"https://www.wikidata.org/wiki/Q677449","display_name":"Aspiration pneumonia","level":3,"score":0.5525920391082764},{"id":"https://openalex.org/C2777184939","wikidata":"https://www.wikidata.org/wiki/Q7920253","display_name":"Ventilator-associated pneumonia","level":3,"score":0.524135172367096},{"id":"https://openalex.org/C2777084678","wikidata":"https://www.wikidata.org/wiki/Q15646788","display_name":"Chlorhexidine","level":2,"score":0.46967631578445435},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4502241313457489},{"id":"https://openalex.org/C547646559","wikidata":"https://www.wikidata.org/wiki/Q162297","display_name":"Hygiene","level":2,"score":0.4173333942890167},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30755746364593506},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.19116836786270142},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12251153588294983},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007326","descriptor_name":"Institutionalization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009735","descriptor_name":"Nursing Homes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010510","descriptor_name":"Periodontal Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D010510","descriptor_name":"Periodontal Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010510","descriptor_name":"Periodontal Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012122","descriptor_name":"Ventilators, Mechanical","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013048","descriptor_name":"Specimen Handling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016321","descriptor_name":"Dental Care for Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017063","descriptor_name":"Outcome Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018410","descriptor_name":"Pneumonia, Bacterial","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D018410","descriptor_name":"Pneumonia, Bacterial","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D018410","descriptor_name":"Pneumonia, Bacterial","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1902/annals.1998.3.1.262","doi":"https://doi.org/10.1902/annals.1998.3.1.262","is_oa":false,"landing_page_url":"https://doi.org/10.1902/annals.1998.3.1.262","pdf_url":null,"source":{"id":"https://openalex.org/S144469688","display_name":"Annals of Periodontology","issn_l":"1553-0841","issn":["1553-0841","2162-5131"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Periodontology","raw_type":"journal-article"},{"id":"pmid:9722710","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9722710","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of periodontology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":106,"referenced_works":["https://openalex.org/W21662801","https://openalex.org/W115540543","https://openalex.org/W207416173","https://openalex.org/W1480105763","https://openalex.org/W1490665380","https://openalex.org/W1570369724","https://openalex.org/W1588210099","https://openalex.org/W1717163386","https://openalex.org/W1833356851","https://openalex.org/W1854025379","https://openalex.org/W1855202831","https://openalex.org/W1923277859","https://openalex.org/W1961748148","https://openalex.org/W1964823995","https://openalex.org/W1965471548","https://openalex.org/W1969590176","https://openalex.org/W1970012883","https://openalex.org/W1975395569","https://openalex.org/W1975422696","https://openalex.org/W1978767704","https://openalex.org/W1982467969","https://openalex.org/W1982839041","https://openalex.org/W1983048999","https://openalex.org/W1983078877","https://openalex.org/W1983983286","https://openalex.org/W1987268130","https://openalex.org/W1995375214","https://openalex.org/W1995861558","https://openalex.org/W1999295302","https://openalex.org/W2002676613","https://openalex.org/W2005758646","https://openalex.org/W2009193473","https://openalex.org/W2013517828","https://openalex.org/W2014460832","https://openalex.org/W2015122391","https://openalex.org/W2015858353","https://openalex.org/W2017287250","https://openalex.org/W2018298362","https://openalex.org/W2018460617","https://openalex.org/W2024631123","https://openalex.org/W2027551858","https://openalex.org/W2027665553","https://openalex.org/W2028743553","https://openalex.org/W2038114251","https://openalex.org/W2040629121","https://openalex.org/W2040919444","https://openalex.org/W2041440721","https://openalex.org/W2041687951","https://openalex.org/W2042168165","https://openalex.org/W2043192496","https://openalex.org/W2043473045","https://openalex.org/W2044610568","https://openalex.org/W2049194973","https://openalex.org/W2049218464","https://openalex.org/W2050996270","https://openalex.org/W2056402864","https://openalex.org/W2057868302","https://openalex.org/W2059315107","https://openalex.org/W2059853659","https://openalex.org/W2062463229","https://openalex.org/W2063875629","https://openalex.org/W2064504081","https://openalex.org/W2066133347","https://openalex.org/W2066608037","https://openalex.org/W2068662374","https://openalex.org/W2070272376","https://openalex.org/W2072654514","https://openalex.org/W2073084834","https://openalex.org/W2076036601","https://openalex.org/W2077850316","https://openalex.org/W2081623930","https://openalex.org/W2091309901","https://openalex.org/W2097108198","https://openalex.org/W2101237743","https://openalex.org/W2109799805","https://openalex.org/W2113076014","https://openalex.org/W2122093336","https://openalex.org/W2125170970","https://openalex.org/W2127503254","https://openalex.org/W2139646149","https://openalex.org/W2140853706","https://openalex.org/W2141037593","https://openalex.org/W2143221249","https://openalex.org/W2146240351","https://openalex.org/W2150092445","https://openalex.org/W2155645538","https://openalex.org/W2158131132","https://openalex.org/W2162030370","https://openalex.org/W2162777736","https://openalex.org/W2163824976","https://openalex.org/W2165104888","https://openalex.org/W2168223076","https://openalex.org/W2169632941","https://openalex.org/W2245917816","https://openalex.org/W2332847148","https://openalex.org/W2338387209","https://openalex.org/W2398771968","https://openalex.org/W2404526930","https://openalex.org/W2409700959","https://openalex.org/W2411553270","https://openalex.org/W2412199595","https://openalex.org/W2413285081","https://openalex.org/W2608991207","https://openalex.org/W2620313260","https://openalex.org/W3143755808","https://openalex.org/W4254581378"],"related_works":["https://openalex.org/W2085115066","https://openalex.org/W2040776923","https://openalex.org/W2030411810","https://openalex.org/W2225891477","https://openalex.org/W7108992631","https://openalex.org/W1971457627","https://openalex.org/W2065860217","https://openalex.org/W2101049134","https://openalex.org/W1982467969","https://openalex.org/W2153159772"],"abstract_inverted_index":{"Systemic":[0],"infection":[1,48],"in":[2,7,33,74,104,111,119,123,145,182,195,209,225,238,266],"the":[3,17,34,64,75,91,124,139,157,164,169,177,183,196,207,230,239,251,262,267],"elderly":[4,36,79,269],"patient":[5],"living":[6],"a":[8,13,117,132,154],"chronic":[9,92],"care":[10,19,93,121,185],"setting":[11,186],"presents":[12],"significant":[14],"burden":[15],"to":[16,23,162,175,228],"health":[18],"system.":[20],"The":[21],"extent":[22],"which":[24,62],"oral":[25,50,59,84,202,233,274],"organisms":[26],"cause":[27,69],"systemic":[28,47],"infections":[29,234,237],"through":[30,53,272],"hematogenous":[31],"dissemination":[32],"institutionalized":[35,240,268],"is":[37,52,115,254,270],"still":[38],"unknown.":[39],"A":[40,218],"more":[41],"likely":[42],"and":[43,68,86,235,247],"common":[44],"route":[45],"of":[46,55,78,96,160,166,168,179,187,211,220,250],"by":[49],"microorganisms":[51],"aspiration":[54,95],"oropharyngeal":[56,97],"fluids":[57,98],"containing":[58],"pathogenic":[60],"microorganisms,":[61],"colonize":[63],"lower":[65,206],"respiratory":[66,170],"tract":[67],"pneumonia.":[70,113],"Respiratory":[71],"pathogens":[72],"emerge":[73],"dental":[76],"plaque":[77],"patients":[80,105,146],"with":[81,100,106,131],"very":[82],"poor":[83],"hygiene":[85,203],"severe":[87],"periodontal":[88],"disease.":[89],"In":[90,127],"setting,":[94],"contaminated":[99],"these":[101,212],"bacteria":[102],"occurs":[103],"diminished":[107],"host":[108],"defenses,":[109],"resulting":[110],"bacterial":[112],"This":[114,189],"also":[116,205],"problem":[118],"intensive":[120],"units":[122],"hospital":[125],"setting.":[126,199],"one":[128],"study,":[129],"pre-rinsing":[130],"0.12%":[133],"chlorhexidine":[134],"gluconate":[135],"mouthwash":[136],"significantly":[137],"lowered":[138],"mortality":[140],"rate":[141],"from":[142],"postsurgical":[143],"pneumonia":[144,181,265],"undergoing":[147],"open":[148],"heart":[149],"surgery.":[150],"Selective":[151],"digestive":[152],"decontamination,":[153],"technique":[155,190],"involving":[156],"topical":[158],"application":[159],"antimicrobials":[161],"reduce":[163,176],"risk":[165,208,263],"colonization":[167],"tract,":[171],"has":[172,191,214],"been":[173,193,216],"used":[174],"incidence":[178],"nosocomial":[180],"acute":[184],"hospitals.":[188],"not":[192,215],"employed":[194],"nursing":[197],"home":[198],"Whether":[200],"improving":[201],"would":[204],"either":[210],"settings":[213],"studied.":[217],"number":[219],"obstacles":[221],"must":[222,244],"be":[223,245],"overcome":[224],"designing":[226],"studies":[227,257],"investigate":[229],"relationship":[231],"between":[232],"lung":[236],"elderly.":[241],"Ethical":[242],"issues":[243],"addressed,":[246],"full":[248],"collaboration":[249],"medical":[252],"team":[253],"required.":[255],"Future":[256],"should":[258],"establish":[259],"whether":[260],"reducing":[261],"for":[264],"possible":[271],"improved":[273],"health.":[275]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
