{"id":"https://openalex.org/W2007356126","doi":"https://doi.org/10.1007/bf02091548","title":"Role of platelet-activating factor in pathogenesis of galactosamine-lipopolysaccharide-induced liver injury","display_name":"Role of platelet-activating factor in pathogenesis of galactosamine-lipopolysaccharide-induced liver injury","publication_year":1996,"publication_date":"1996-05-01","ids":{"openalex":"https://openalex.org/W2007356126","doi":"https://doi.org/10.1007/bf02091548","mag":"2007356126","pmid":"https://pubmed.ncbi.nlm.nih.gov/8625746"},"language":"en","primary_location":{"id":"doi:10.1007/bf02091548","doi":"https://doi.org/10.1007/bf02091548","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02091548","pdf_url":null,"source":{"id":"https://openalex.org/S194656152","display_name":"Digestive Diseases and Sciences","issn_l":"0163-2116","issn":["0163-2116","1573-2568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive Diseases and Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024245013","display_name":"Yutaka Komatsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaka Komatsu","raw_affiliation_strings":["Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111566735","display_name":"Yasushi Shiratori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Shiratori","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113592644","display_name":"Yohko Hikiba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yohko Hikiba","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003339273","display_name":"Naoaki Hashimoto","orcid":"https://orcid.org/0000-0001-6264-1346","observed_orcids":["https://orcid.org/0000-0001-6264-1346"]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoaki Hashimoto","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108250648","display_name":"Katsuken Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuken Han","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109880632","display_name":"Tateo Kawase","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tateo Kawase","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110044925","display_name":"Haruhiko Yoshida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Haruhiko Yoshida","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113917456","display_name":"Kenichi Okano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ken'ichi Okano","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034244372","display_name":"Masao Omata","orcid":"https://orcid.org/0000-0001-7977-1497","observed_orcids":["https://orcid.org/0000-0001-7977-1497"]},"institutions":[{"id":"https://openalex.org/I4210087332","display_name":"The Institute of Medical Science, Asahi Life Foundation","ror":"https://ror.org/000hskt11","country_code":"JP","type":"other","lineage":["https://openalex.org/I4210087332"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao Omata","raw_affiliation_strings":["Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, 1-9-14 Nishi-Shin'juku, Shin'juku-ku, 160, Tokyo, Japan","institution_ids":["https://openalex.org/I4210087332"]},{"raw_affiliation_string":"From the Department of Internal Medicine II and I, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.12696942,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"5","first_page":"1030","last_page":"1037"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/platelet-activating-factor","display_name":"platelet-activating factor","score":1.0},{"id":"https://openalex.org/keywords/web-2086","display_name":"WEB 2086","score":0.8339999914169312},{"id":"https://openalex.org/keywords/paf-receptor-antagonist","display_name":"PAF receptor antagonists","score":0.9879999756813049},{"id":"https://openalex.org/keywords/neutrophil-adhesion","display_name":"neutrophil adhesion","score":0.8870000243186951},{"id":"https://openalex.org/keywords/hepatic-endothelial-cells","display_name":"hepatic endothelial cells","score":0.9679999947547913},{"id":"https://openalex.org/keywords/neutrophil-accumulation","display_name":"neutrophil accumulation","score":0.765999972820282},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9459999799728394},{"id":"https://openalex.org/keywords/liver-injury-pathogenesis","display_name":"liver injury pathogenesis","score":0.6800000071525574}],"concepts":[{"id":"https://openalex.org/C2780955469","wikidata":"https://www.wikidata.org/wiki/Q15320063","display_name":"Platelet-activating factor receptor","level":4,"score":0.8947241306304932},{"id":"https://openalex.org/C2779020240","wikidata":"https://www.wikidata.org/wiki/Q420577","display_name":"Platelet-activating factor","level":2,"score":0.7810531854629517},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.6784228682518005},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6159802079200745},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5572592616081238},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5174225568771362},{"id":"https://openalex.org/C2776637226","wikidata":"https://www.wikidata.org/wiki/Q6658207","display_name":"Liver injury","level":2,"score":0.4917915165424347},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46958035230636597},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4490375220775604},{"id":"https://openalex.org/C41260117","wikidata":"https://www.wikidata.org/wiki/Q668064","display_name":"Hepatology","level":2,"score":0.42818111181259155},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.42522525787353516},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4015466570854187},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.39288583397865295},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.38533109426498413},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.380029559135437},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37083953619003296},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3438635468482971},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.34220391511917114},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23069792985916138},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09972342848777771},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001381","descriptor_name":"Azepines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004727","descriptor_name":"Endothelium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004727","descriptor_name":"Endothelium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005688","descriptor_name":"Galactosamine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010972","descriptor_name":"Platelet Activating Factor","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010972","descriptor_name":"Platelet Activating Factor","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014230","descriptor_name":"Triazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056486","descriptor_name":"Chemical and Drug Induced Liver Injury","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D056486","descriptor_name":"Chemical and Drug Induced Liver Injury","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02091548","doi":"https://doi.org/10.1007/bf02091548","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02091548","pdf_url":null,"source":{"id":"https://openalex.org/S194656152","display_name":"Digestive Diseases and Sciences","issn_l":"0163-2116","issn":["0163-2116","1573-2568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive Diseases and Sciences","raw_type":"journal-article"},{"id":"pmid:8625746","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8625746","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive diseases and sciences","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1412832532","https://openalex.org/W1515398907","https://openalex.org/W1527489591","https://openalex.org/W1617264430","https://openalex.org/W1634308456","https://openalex.org/W1905241259","https://openalex.org/W1925403052","https://openalex.org/W1965737875","https://openalex.org/W1977363772","https://openalex.org/W1986092783","https://openalex.org/W1986687865","https://openalex.org/W1989452382","https://openalex.org/W2003219651","https://openalex.org/W2013848151","https://openalex.org/W2015312259","https://openalex.org/W2034681350","https://openalex.org/W2034764241","https://openalex.org/W2050069116","https://openalex.org/W2051611904","https://openalex.org/W2052445471","https://openalex.org/W2056129425","https://openalex.org/W2056225363","https://openalex.org/W2057905142","https://openalex.org/W2073620332","https://openalex.org/W2086069132","https://openalex.org/W2088569358","https://openalex.org/W2090827824","https://openalex.org/W2095361274","https://openalex.org/W2101615486","https://openalex.org/W2107228070","https://openalex.org/W2108962054","https://openalex.org/W2111202522","https://openalex.org/W2113296405","https://openalex.org/W2252056675","https://openalex.org/W2261984195","https://openalex.org/W2276169428","https://openalex.org/W2395692432","https://openalex.org/W2401058224","https://openalex.org/W2411096060","https://openalex.org/W2418791966","https://openalex.org/W2441693106","https://openalex.org/W4313310702"],"related_works":["https://openalex.org/W2440419164","https://openalex.org/W2032531869","https://openalex.org/W2091239442","https://openalex.org/W313036842","https://openalex.org/W2050296855","https://openalex.org/W2014489533","https://openalex.org/W2399472478","https://openalex.org/W2051267141","https://openalex.org/W2095361274","https://openalex.org/W2374405979"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}