{"id":"https://openalex.org/W2007274659","doi":"https://doi.org/10.1021/bi034038a","title":"Structural Study of GCDFP-15/gp17 in Disease versus Physiological Conditions Using a Proteomic Approach","display_name":"Structural Study of GCDFP-15/gp17 in Disease versus Physiological Conditions Using a Proteomic Approach","publication_year":2003,"publication_date":"2003-04-29","ids":{"openalex":"https://openalex.org/W2007274659","doi":"https://doi.org/10.1021/bi034038a","mag":"2007274659","pmid":"https://pubmed.ncbi.nlm.nih.gov/12755619"},"language":"en","primary_location":{"id":"doi:10.1021/bi034038a","doi":"https://doi.org/10.1021/bi034038a","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi034038a","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028654545","display_name":"Emilia Caputo","orcid":"https://orcid.org/0000-0002-6485-8802","observed_orcids":["https://orcid.org/0000-0002-6485-8802"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":true,"raw_author_name":"Emilia Caputo","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030112845","display_name":"Alessandra Camarca","orcid":"https://orcid.org/0000-0001-7546-7527","observed_orcids":["https://orcid.org/0000-0001-7546-7527"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Alessandra Camarca","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039486305","display_name":"Ramy Moharram","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Ramy Moharram","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087349556","display_name":"Peter Tornatore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Peter Tornatore","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050576967","display_name":"Bradley J. Thatcher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Bradley Thatcher","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060865245","display_name":"John Guardiola","orcid":"https://orcid.org/0000-0002-4934-8628","observed_orcids":["https://orcid.org/0000-0002-4934-8628"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"John Guardiola","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113601445","display_name":"Brian M. Martin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Brian M. Martin","raw_affiliation_strings":["Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Molecular Structures, LNT, NIMH, NIH, 10 Center Drive, Building 10 3N309, Bethesda, Maryland 20892-1262, Institute of Genetics and Biophysics-I.G.B., A. Buzzati-Traverso-, CNR, Via G. Marconi 10, I-80125 Naples, Italy, Ciphergen Biosystems, Fremont, California, and Protein Solutions, 347 Maple Avenue, Stratford, ON, Canada N5A 7P6","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5028654545"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210137461"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.8081,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.67680424,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"42","issue":"20","first_page":"6169","last_page":"6178"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.5005000233650208,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.5005000233650208,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.21459999680519104,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.1876000016927719,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gcdfp-15","display_name":"GCDFP-15","score":0.9900000095367432},{"id":"https://openalex.org/keywords/prolactin-inducible-protein","display_name":"prolactin-inducible protein","score":0.9629999995231628},{"id":"https://openalex.org/keywords/fibronectin-cleavage","display_name":"fibronectin cleavage","score":0.8569999933242798},{"id":"https://openalex.org/keywords/aspartic-protease","display_name":"aspartic protease","score":0.9120000004768372},{"id":"https://openalex.org/keywords/protein-conformation","display_name":"protein conformation","score":0.7680000066757202},{"id":"https://openalex.org/keywords/n-glycosylation","display_name":"N-glycosylation","score":0.9300000071525574},{"id":"https://openalex.org/keywords/post-translational-modification","display_name":"post-translational modification","score":0.871999979019165},{"id":"https://openalex.org/keywords/cd4-binding","display_name":"CD4 binding","score":0.972000002861023},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.7250000238418579}],"concepts":[{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.6131356358528137},{"id":"https://openalex.org/C2777313579","wikidata":"https://www.wikidata.org/wiki/Q898365","display_name":"Glycosylation","level":2,"score":0.602509081363678},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5317992568016052},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.5154162645339966},{"id":"https://openalex.org/C116084860","wikidata":"https://www.wikidata.org/wiki/Q48255","display_name":"Gel electrophoresis","level":2,"score":0.4725501239299774},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4588210880756378},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37292683124542236},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3640698492527008},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001053","descriptor_name":"Apolipoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001053","descriptor_name":"Apolipoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001053","descriptor_name":"Apolipoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015704","descriptor_name":"CD4 Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015704","descriptor_name":"CD4 Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015704","descriptor_name":"CD4 Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053399","descriptor_name":"Apolipoproteins D","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053399","descriptor_name":"Apolipoproteins D","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053399","descriptor_name":"Apolipoproteins D","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/bi034038a","doi":"https://doi.org/10.1021/bi034038a","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi034038a","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:12755619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12755619","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.46000000834465027,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W315895210","https://openalex.org/W1532673576","https://openalex.org/W1949900960","https://openalex.org/W1995222834","https://openalex.org/W2011020291","https://openalex.org/W2011807125","https://openalex.org/W2015013331","https://openalex.org/W2074022831","https://openalex.org/W2079592207","https://openalex.org/W2090384425","https://openalex.org/W2091148915","https://openalex.org/W2093526201","https://openalex.org/W2113654582","https://openalex.org/W2130184077","https://openalex.org/W2135064875","https://openalex.org/W2147451877","https://openalex.org/W4300122725"],"related_works":["https://openalex.org/W106404930","https://openalex.org/W2049617858","https://openalex.org/W618082125","https://openalex.org/W3176453265","https://openalex.org/W2134517942","https://openalex.org/W4408141896","https://openalex.org/W2109453151","https://openalex.org/W2090384425","https://openalex.org/W4313279022","https://openalex.org/W4247830048"],"abstract_inverted_index":{"Gross":[0],"cystic":[1],"disease":[2,95],"fluid":[3],"protein":[4,10,27,167,226],"(GCDFP-15),":[5],"also":[6,20],"known":[7],"as":[8,22,33,82,162],"prolactin-inducible":[9],"(PIP),":[11],"is":[12,19,41,244],"a":[13,52,148],"specific":[14,210],"breast":[15],"tumor":[16,57],"marker.":[17],"GCDFP-15/PIP":[18,161],"identified":[21],"gp17":[23],"and/or":[24,130],"seminal":[25,30],"actin-binding":[26],"(SABP)":[28],"from":[29,37],"vesicles":[31],"and":[32,59,85,104,118,172,190,235],"extraparotid":[34],"glycoprotein":[35],"(EP-GP)":[36],"salivary":[38],"glands.":[39],"It":[40],"an":[42,77],"aspartyl":[43],"proteinase":[44],"able":[45],"to":[46,65,74,204,230],"specifically":[47],"cleave":[48],"fibronectin":[49],"(FN),":[50],"suggesting":[51,127],"possible":[53],"involvement":[54],"in":[55,159,201,239],"mammary":[56],"progression":[58],"fertilization.":[60],"Other":[61],"functions":[62],"were":[63],"attributed":[64],"this":[66,214],"protein(s)":[67,93],"on":[68,221],"the":[69,89,92,135,183,195,202,209,225,240],"basis":[70],"of":[71,79,91,134,178,185,213],"its":[72,222,231,237],"ability":[73],"interact":[75],"with":[76,164,188],"array":[78],"molecules":[80,234],"such":[81],"CD4,":[83],"actin,":[84],"fibrinogen.":[86],"We":[87,192],"investigated":[88],"structure":[90,140],"under":[94],"versus":[96],"physiological":[97,165,196],"conditions":[98],"by":[99,115,143,168],"RP-HPLC":[100,116],"chromatography,":[101],"ProteinChip":[102,173,179],"technology,":[103,180],"QStar":[105],"MS/MS":[106,144],"mass":[107,125],"spectrometry.":[108],"The":[109],"proteins":[110,187],"behaved":[111],"differently":[112,228],"when":[113],"examined":[114],"chromatography":[117],"surface-enhanced":[119],"laser":[120],"desorption":[121],"ionization":[122],"time-of-flight":[123],"(SELDI-TOF)":[124],"spectrometry,":[126],"different":[128,153],"conformations":[129],"tissue-specific":[131],"posttranslational":[132],"modifications":[133],"proteins,":[136],"although":[137],"their":[138],"primary":[139],"was":[141,157,198],"identical":[142],"analysis.":[145],"Both":[146],"showed":[147],"single":[149],"N-glycosylation":[150],"site.":[151],"A":[152],"N-linked":[154],"glycosylation":[155],"pattern":[156],"observed":[158,193],"pathological":[160],"compared":[163],"gp17/SABP":[166],"coupling":[169],"enzymatic":[170],"digestion":[171],"technology.":[174],"Furthermore,":[175],"taking":[176],"advantage":[177],"we":[181,207],"analyzed":[182],"interaction":[184],"both":[186],"CD4":[189],"FN.":[191],"that":[194],"form":[197],"mainly":[199],"involved":[200],"binding":[203,233],"CD4.":[205],"Moreover,":[206],"defined":[208],"FN":[211],"binding-domain":[212],"protein.":[215],"These":[216],"data":[217],"suggested":[218],"that,":[219],"depending":[220],"conformational":[223],"state,":[224],"could":[227],"bind":[229],"various":[232],"change":[236],"function(s)":[238],"microenviroments":[241],"where":[242],"it":[243],"expressed.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}