{"id":"https://openalex.org/W2007227258","doi":"https://doi.org/10.3171/jns.1978.49.2.0229","title":"Cerebral vasospasm and ultrastructural changes in cerebral arterial wall: An experimental study","display_name":"Cerebral vasospasm and ultrastructural changes in cerebral arterial wall: An experimental study","publication_year":1978,"publication_date":"1978-08-01","ids":{"openalex":"https://openalex.org/W2007227258","doi":"https://doi.org/10.3171/jns.1978.49.2.0229","mag":"2007227258","pmid":"https://pubmed.ncbi.nlm.nih.gov/671076"},"language":"en","primary_location":{"id":"doi:10.3171/jns.1978.49.2.0229","doi":"https://doi.org/10.3171/jns.1978.49.2.0229","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1978.49.2.0229","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056832629","display_name":"Yusuke Tanabe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yusuke Tanabe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019676994","display_name":"Kazuki Sakata","orcid":"https://orcid.org/0009-0004-9952-9584","observed_orcids":["https://orcid.org/0009-0004-9952-9584"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuki Sakata","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109846792","display_name":"Hiromu Yamada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiromu Yamada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065663105","display_name":"Takao Ito","orcid":"https://orcid.org/0000-0001-6224-5204","observed_orcids":["https://orcid.org/0000-0001-6224-5204"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takao Ito","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103695408","display_name":"Mitsuaki Takada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitsuaki Takada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.771,"has_fulltext":false,"cited_by_count":182,"citation_normalized_percentile":{"value":0.97749154,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"49","issue":"2","first_page":"229","last_page":"238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12082","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-vasospasm","display_name":"cerebral vasospasm","score":0.9819999933242798},{"id":"https://openalex.org/keywords/subarachnoid-hemorrhage","display_name":"subarachnoid hemorrhage","score":0.9940000176429749},{"id":"https://openalex.org/keywords/reserpine","display_name":"reserpine","score":0.6800000071525574},{"id":"https://openalex.org/keywords/endothelial-cell-detachment","display_name":"endothelial cell detachment","score":0.6610000133514404},{"id":"https://openalex.org/keywords/intimal-thickening","display_name":"intimal thickening","score":0.9549999833106995},{"id":"https://openalex.org/keywords/basal-cerebral-arteries","display_name":"basal cerebral arteries","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8285577297210693},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.6964529156684875},{"id":"https://openalex.org/C2777736543","wikidata":"https://www.wikidata.org/wiki/Q693442","display_name":"Subarachnoid hemorrhage","level":2,"score":0.6577110290527344},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6126081943511963},{"id":"https://openalex.org/C2778506911","wikidata":"https://www.wikidata.org/wiki/Q2849606","display_name":"Vasospasm","level":3,"score":0.5551763772964478},{"id":"https://openalex.org/C2779537118","wikidata":"https://www.wikidata.org/wiki/Q618362","display_name":"Arterial blood","level":2,"score":0.5493898987770081},{"id":"https://openalex.org/C3020090656","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Arterial wall","level":2,"score":0.5414914488792419},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.5038449168205261},{"id":"https://openalex.org/C102568950","wikidata":"https://www.wikidata.org/wiki/Q127702","display_name":"Vacuole","level":3,"score":0.5013439655303955},{"id":"https://openalex.org/C153400128","wikidata":"https://www.wikidata.org/wiki/Q3150731","display_name":"Infiltration (HVAC)","level":2,"score":0.49880194664001465},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4720897376537323},{"id":"https://openalex.org/C2780813603","wikidata":"https://www.wikidata.org/wiki/Q268930","display_name":"Subarachnoid space","level":3,"score":0.45601892471313477},{"id":"https://openalex.org/C2776820941","wikidata":"https://www.wikidata.org/wiki/Q5064103","display_name":"Cerebral vasospasm","level":4,"score":0.44465944170951843},{"id":"https://openalex.org/C171614378","wikidata":"https://www.wikidata.org/wiki/Q5064093","display_name":"Cerebral arteries","level":2,"score":0.4289955198764801},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.25355494022369385},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21558597683906555},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.15704354643821716},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1055651605129242},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001769","descriptor_name":"Blood","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002536","descriptor_name":"Cerebral Arteries","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D002546","descriptor_name":"Ischemic Attack, Transient","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002546","descriptor_name":"Ischemic Attack, Transient","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007267","descriptor_name":"Injections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009897","descriptor_name":"Optic Chiasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012110","descriptor_name":"Reserpine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3171/jns.1978.49.2.0229","doi":"https://doi.org/10.3171/jns.1978.49.2.0229","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1978.49.2.0229","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},{"id":"pmid:671076","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/671076","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurosurgery","raw_type":"Journal Article"},{"id":"mag:2363478464","doi":null,"is_oa":false,"landing_page_url":"https://thejns.org/doi/pdf/10.3171/jns.1978.49.2.0229","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W85520924","https://openalex.org/W383990420","https://openalex.org/W1990349288","https://openalex.org/W2037116813","https://openalex.org/W2039310958","https://openalex.org/W2069200235","https://openalex.org/W2070049965","https://openalex.org/W2091230510","https://openalex.org/W2104900684","https://openalex.org/W2130300107","https://openalex.org/W2141225467","https://openalex.org/W2158837719","https://openalex.org/W2416556964","https://openalex.org/W2427647898"],"related_works":["https://openalex.org/W2363478464","https://openalex.org/W2061095323","https://openalex.org/W2068967280","https://openalex.org/W2006358310","https://openalex.org/W2348776866","https://openalex.org/W2401136149","https://openalex.org/W2037654220","https://openalex.org/W2040129461","https://openalex.org/W2353382285","https://openalex.org/W2135035401"],"abstract_inverted_index":{"\u2713":[0],"Subarachnoid":[1],"hemorrhage":[2],"(SAH)":[3],"was":[4,220],"produced":[5],"experimentally":[6],"by":[7,254],"injecting":[8],"normal":[9,34,102,235],"dog's":[10,16,35,103,194,236],"blood":[11,17,237],"as":[12,14,53,121,157,239],"well":[13],"reserpinized":[15,193],"into":[18],"the":[19,23,37,40,105,108,199,204,213,216,223,227],"chiasmal":[20],"cistern":[21],"of":[22,39,49,55,64,68,107,117,124,128,135,139,145,198,203,215,242],"dog.":[24],"The":[25,74,244],"following":[26,190],"observations":[27],"were":[28,209],"made:":[29],"1)":[30],"After":[31,99],"SAH":[32,100,191,233],"with":[33,101,192,234],"blood,":[36,104,195],"intima":[38,200],"basal":[41,109,205],"truncal":[42,110,206],"arterial":[43,111,207,229],"wall":[44,112,208,230],"showed":[45,113],"some":[46,114],"or":[47,115],"all":[48,116],"such":[50,118],"ultrastructural":[51,119,196,224],"changes":[52,75,120,225],"appearance":[54,67,127,134,143],"vacuoles":[56,130],"and":[57,71,90,131,142,159,177,187,201],"dense":[58,132,146],"bodies":[59],"in":[60,151,226,249],"endothelial":[61,65],"cells,":[62,66,70,126],"detachment":[63],"intimal":[69,72],"thickening.":[73],"first":[76,163],"appeared":[77,164],"2":[78,165],"hours":[79,166],"after":[80,88,96,167,175,183,232],"SAH,":[81,89,168,176],"culminated":[82,169],"at":[83,170],"3":[84],"to":[85,93,154,172,180],"7":[86],"days":[87,189],"persisted":[91,178],"up":[92,179],"1":[94,171,181],"month":[95],"SAH.":[97,184],"2)":[98],"media":[106,202],"moth-eaten":[122],"contour":[123],"muscle":[125],"intracytoplasmic":[129],"bodies,":[133],"cell":[136],"debris,":[137],"enlargement":[138],"interstitial":[140],"space,":[141],"therein":[144],"particles.":[147],"These":[148],"findings,":[149,218],"which,":[150],"short,":[152],"are":[153],"be":[155,252,258],"expressed":[156],"myonecrosis":[158],"its":[160],"repairing":[161],"process,":[162],"4":[173],"months":[174],"year":[182],"3)":[185],"Three":[186],"5":[188],"findings":[197],"entirely":[210],"normal.":[211],"On":[212],"basis":[214],"above":[217],"it":[219],"concluded":[221],"that":[222,246],"cerebral":[228],"observed":[231],"occurred":[238],"a":[240],"consequence":[241],"vasospasm.":[243],"possibility":[245],"late":[247],"spasm,":[248],"turn,":[250],"might":[251],"facilitated":[253],"myonecrosis,":[255],"could":[256],"not":[257],"denied.":[259]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}