{"id":"https://openalex.org/W2007192196","doi":"https://doi.org/10.1002/aic.690370912","title":"Electrostatic potentials and protein partitioning in aqueous two\u2010phase systems","display_name":"Electrostatic potentials and protein partitioning in aqueous two\u2010phase systems","publication_year":1991,"publication_date":"1991-09-01","ids":{"openalex":"https://openalex.org/W2007192196","doi":"https://doi.org/10.1002/aic.690370912","mag":"2007192196"},"language":"en","primary_location":{"id":"doi:10.1002/aic.690370912","doi":"https://doi.org/10.1002/aic.690370912","is_oa":false,"landing_page_url":"https://doi.org/10.1002/aic.690370912","pdf_url":null,"source":{"id":"https://openalex.org/S147177414","display_name":"AIChE Journal","issn_l":"0001-1541","issn":["0001-1541","1547-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIChE Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108456602","display_name":"Charles A. Haynes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. A. Haynes","raw_affiliation_strings":["Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","Department of Chemical Engineering , University of California , Berkeley, CA, 94720"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering , University of California , Berkeley, CA, 94720","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005417885","display_name":"J. E. Carson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Carson","raw_affiliation_strings":["Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","Department of Chemical Engineering , University of California , Berkeley, CA, 94720"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering , University of California , Berkeley, CA, 94720","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109919878","display_name":"Harvey W. Blanch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. W. Blanch","raw_affiliation_strings":["Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","Department of Chemical Engineering , University of California , Berkeley, CA, 94720"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering , University of California , Berkeley, CA, 94720","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020540558","display_name":"John M. Prausnitz","orcid":"https://orcid.org/0000-0001-9458-0648","observed_orcids":["https://orcid.org/0000-0001-9458-0648"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. M. Prausnitz","raw_affiliation_strings":["Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","Department of Chemical Engineering , University of California , Berkeley, CA, 94720"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Chemical Engineering, University of California, Berkeley, CA 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering , University of California , Berkeley, CA, 94720","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":{"value":4940,"currency":"USD","value_usd":4940},"apc_paid":null,"fwci":2.9878,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.89373297,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"37","issue":"9","first_page":"1401","last_page":"1409"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11936","display_name":"Chemical and Physical Properties in Aqueous Solutions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1506","display_name":"Filtration and Separation"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11936","display_name":"Chemical and Physical Properties in Aqueous Solutions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1506","display_name":"Filtration and Separation"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10402","display_name":"Phase Equilibria and Thermodynamics","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12274","display_name":"Electrostatics and Colloid Interactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aqueous-two-phase-systems","display_name":"aqueous two-phase systems","score":0.9539999961853027},{"id":"https://openalex.org/keywords/protein-partitioning","display_name":"protein partitioning","score":0.7210000157356262},{"id":"https://openalex.org/keywords/partition-coefficient","display_name":"partition coefficient","score":0.7039999961853027},{"id":"https://openalex.org/keywords/alpha-cyclodextrin","display_name":"\u03b1-cyclodextrin","score":0.9200000166893005},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.8840000033378601},{"id":"https://openalex.org/keywords/dextran","display_name":"dextran","score":0.875},{"id":"https://openalex.org/keywords/lysozyme","display_name":"lysozyme","score":0.871999979019165},{"id":"https://openalex.org/keywords/alpha-chymotrypsin","display_name":"alpha-chymotrypsin","score":0.9580000042915344},{"id":"https://openalex.org/keywords/bovine-serum-albumin","display_name":"bovine serum albumin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/thermodynamic-analysis","display_name":"thermodynamic analysis","score":0.6899999976158142}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8111348748207092},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.7326334714889526},{"id":"https://openalex.org/C192552737","wikidata":"https://www.wikidata.org/wiki/Q898797","display_name":"Partition coefficient","level":2,"score":0.6665650010108948},{"id":"https://openalex.org/C2777516009","wikidata":"https://www.wikidata.org/wiki/Q194207","display_name":"Ethylene glycol","level":2,"score":0.6156343221664429},{"id":"https://openalex.org/C117626034","wikidata":"https://www.wikidata.org/wiki/Q26336","display_name":"Electrostatics","level":2,"score":0.534112274646759},{"id":"https://openalex.org/C2776966407","wikidata":"https://www.wikidata.org/wiki/Q24779410","display_name":"Lysozyme","level":2,"score":0.526885986328125},{"id":"https://openalex.org/C149556010","wikidata":"https://www.wikidata.org/wiki/Q4782870","display_name":"Aqueous two-phase system","level":3,"score":0.5204558372497559},{"id":"https://openalex.org/C86807702","wikidata":"https://www.wikidata.org/wiki/Q2620381","display_name":"Bovine serum albumin","level":2,"score":0.5069589614868164},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.4873264729976654},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.4667198061943054},{"id":"https://openalex.org/C196806460","wikidata":"https://www.wikidata.org/wiki/Q188603","display_name":"Capillary action","level":2,"score":0.44633257389068604},{"id":"https://openalex.org/C2779433975","wikidata":"https://www.wikidata.org/wiki/Q40417805","display_name":"Cyclodextrin","level":2,"score":0.4368533492088318},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.43015575408935547},{"id":"https://openalex.org/C2778870691","wikidata":"https://www.wikidata.org/wiki/Q44794658","display_name":"Iodide","level":2,"score":0.4253215193748474},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.31086456775665283},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.2431921362876892},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.23485416173934937},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.16730350255966187},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/aic.690370912","doi":"https://doi.org/10.1002/aic.690370912","is_oa":false,"landing_page_url":"https://doi.org/10.1002/aic.690370912","pdf_url":null,"source":{"id":"https://openalex.org/S147177414","display_name":"AIChE Journal","issn_l":"0001-1541","issn":["0001-1541","1547-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIChE Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1965743348","https://openalex.org/W1984608720","https://openalex.org/W2011065747","https://openalex.org/W2015766037","https://openalex.org/W2017302825","https://openalex.org/W2035695555","https://openalex.org/W2045465473","https://openalex.org/W2048068493","https://openalex.org/W2091157636","https://openalex.org/W2137816689","https://openalex.org/W2225601529","https://openalex.org/W2505223031","https://openalex.org/W4300606575","https://openalex.org/W4317417044","https://openalex.org/W4353062908"],"related_works":["https://openalex.org/W1486315184","https://openalex.org/W4234034550","https://openalex.org/W2149185856","https://openalex.org/W254486677","https://openalex.org/W2415584495","https://openalex.org/W2080526253","https://openalex.org/W1984608720","https://openalex.org/W2087655521","https://openalex.org/W2095713959","https://openalex.org/W2096928002"],"abstract_inverted_index":{"Abstract":[0],"A":[1],"thermodynamic":[2],"analysis":[3],"unambiguously":[4],"relates":[5],"interfacial\u2010electrostatic\u2010potential":[6],"differences":[7],"measured":[8,26],"with":[9,121],"Ag/AgCl":[10],"capillary":[11],"electrodes":[12],"to":[13,74,102,113],"the":[14,59,66,95,105],"equilibrium":[15],"properties":[16],"of":[17,30,69,97,108],"an":[18,35],"aqueous":[19,36],"two\u2010phase":[20,37],"system.":[21],"Interfacial":[22],"electrostatic":[23,61],"potentials":[24],"were":[25],"as":[27,65,94],"a":[28],"function":[29],"total":[31,67],"\u03b1\u2010cyclodextrin":[32,70,90,98],"concentration":[33,68,96],"in":[34,58,118],"system":[38],"containing":[39],"9.1":[40],"wt.":[41,47],"%":[42,48],"poly":[43],"(ethylene":[44],"glycol),":[45],"6.1":[46],"Dextran":[49],"T\u201070,":[50],"and":[51,83],"1\u2010mM":[52],"potassium":[53],"iodide.":[54],"An":[55],"order\u2010of\u2010magnitude":[56],"increase":[57],"interfacial":[60],"potential":[62],"was":[63],"observed":[64],"increased":[71],"from":[72,100,111],"0":[73,101],"1":[75,103],"mM.":[76],"Measured":[77],"partition":[78,106],"coefficients":[79],"for":[80],"\u03b1\u2010chymotrypsin,":[81],"lysozyme,":[82],"bovine":[84],"serum":[85],"albumin":[86],"depend":[87],"strongly":[88],"on":[89],"concentration.":[91],"For":[92],"example,":[93],"rises":[99],"mM,":[104],"coefficient":[107],"lysozyme":[109],"decreases":[110],"1.7":[112],"0.55.":[114],"These":[115],"measurements":[116],"are":[117],"good":[119],"agreement":[120],"theoretical":[122],"expectations.":[123]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}