{"id":"https://openalex.org/W2007134057","doi":"https://doi.org/10.1007/s11596-008-0224-4","title":"Effects of hyperoxia on mitochondrial multienzyme complex III and V in premature newborn rat lung","display_name":"Effects of hyperoxia on mitochondrial multienzyme complex III and V in premature newborn rat lung","publication_year":2008,"publication_date":"2008-04-01","ids":{"openalex":"https://openalex.org/W2007134057","doi":"https://doi.org/10.1007/s11596-008-0224-4","mag":"2007134057","pmid":"https://pubmed.ncbi.nlm.nih.gov/18481000"},"language":"en","primary_location":{"id":"doi:10.1007/s11596-008-0224-4","doi":"https://doi.org/10.1007/s11596-008-0224-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11596-008-0224-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210175609","display_name":"Journal of Huazhong University of Science and Technology [Medical Sciences]","issn_l":"1672-0733","issn":["1672-0733","0510-9752","1993-1352"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310311954","host_organization_name":"Huazhong University of Science and Technology","host_organization_lineage":["https://openalex.org/P4310311954"],"host_organization_lineage_names":["Huazhong University of Science and Technology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Huazhong University of Science and Technology [Medical Sciences]","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101828461","display_name":"Cai Cheng","orcid":"https://orcid.org/0000-0002-3780-1720","observed_orcids":["https://orcid.org/0000-0002-3780-1720"]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng Cai","raw_affiliation_strings":["Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000118476","display_name":"Li\u2010Wen Chang","orcid":"https://orcid.org/0000-0001-9764-6278","observed_orcids":["https://orcid.org/0000-0001-9764-6278"]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liwen Chang","raw_affiliation_strings":["Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100463016","display_name":"Wenbin Li","orcid":"https://orcid.org/0000-0003-3096-4831","observed_orcids":["https://orcid.org/0000-0003-3096-4831"]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenbin Li","raw_affiliation_strings":["Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100431996","display_name":"Wei Liu","orcid":"https://orcid.org/0000-0003-4199-5406","observed_orcids":["https://orcid.org/0000-0003-4199-5406"]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Liu","raw_affiliation_strings":["Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Tongji Hospital,#R##N#Tongji Medical College, #R##N#Huazhong University of Science and Technology","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5000118476"],"corresponding_institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"],"apc_list":null,"apc_paid":null,"fwci":0.6128,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.74596834,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"2","first_page":"207","last_page":"210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9467999935150146,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9467999935150146,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.03840000182390213,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperoxia","display_name":"hyperoxia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/mitochondrial-complex-iii","display_name":"mitochondrial complex III","score":0.7549999952316284},{"id":"https://openalex.org/keywords/cytochrome-b","display_name":"cytochrome b","score":0.9449999928474426},{"id":"https://openalex.org/keywords/atp-synthase","display_name":"ATP synthase","score":0.746999979019165},{"id":"https://openalex.org/keywords/atp-synthase-subunit-6","display_name":"ATP synthase subunit 6","score":0.8320000171661377},{"id":"https://openalex.org/keywords/mitochondrial-uncoupling","display_name":"mitochondrial uncoupling","score":0.9100000262260437},{"id":"https://openalex.org/keywords/hyperoxia-induced-lung-injury","display_name":"hyperoxia-induced lung injury","score":0.8849999904632568},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.6890000104904175},{"id":"https://openalex.org/keywords/electron-transport-chain","display_name":"electron transport chain","score":0.6990000009536743},{"id":"https://openalex.org/keywords/oxygen-toxicity","display_name":"oxygen toxicity","score":0.6340000033378601},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.37700000405311584},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.3630000054836273}],"concepts":[{"id":"https://openalex.org/C2780672939","wikidata":"https://www.wikidata.org/wiki/Q5958429","display_name":"Hyperoxia","level":3,"score":0.8913450241088867},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.7647703289985657},{"id":"https://openalex.org/C85265743","wikidata":"https://www.wikidata.org/wiki/Q885458","display_name":"Blot","level":3,"score":0.6061521768569946},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6033351421356201},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5620936155319214},{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.5133525729179382},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5104626417160034},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.47992950677871704},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.46799442172050476},{"id":"https://openalex.org/C20564796","wikidata":"https://www.wikidata.org/wiki/Q1428108","display_name":"Room air distribution","level":2,"score":0.4476979672908783},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22018471360206604},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21828803420066833},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12809845805168152},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12406638264656067},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003576","descriptor_name":"Electron Transport Complex IV","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009097","descriptor_name":"Multienzyme Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014450","descriptor_name":"Electron Transport Complex III","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018496","descriptor_name":"Hyperoxia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045303","descriptor_name":"Cytochromes b","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11596-008-0224-4","doi":"https://doi.org/10.1007/s11596-008-0224-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11596-008-0224-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210175609","display_name":"Journal of Huazhong University of Science and Technology [Medical Sciences]","issn_l":"1672-0733","issn":["1672-0733","0510-9752","1993-1352"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310311954","host_organization_name":"Huazhong University of Science and Technology","host_organization_lineage":["https://openalex.org/P4310311954"],"host_organization_lineage_names":["Huazhong University of Science and Technology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Huazhong University of Science and Technology [Medical Sciences]","raw_type":"journal-article"},{"id":"pmid:18481000","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18481000","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1967567029","https://openalex.org/W1976296623","https://openalex.org/W2019399278","https://openalex.org/W2031348767","https://openalex.org/W2043217415","https://openalex.org/W2053133117","https://openalex.org/W2083275820","https://openalex.org/W2123968840","https://openalex.org/W2142315689","https://openalex.org/W2152689397","https://openalex.org/W2160444104","https://openalex.org/W2160772865","https://openalex.org/W2378046646","https://openalex.org/W2994294422"],"related_works":["https://openalex.org/W2392617244","https://openalex.org/W2350601655","https://openalex.org/W2374953981","https://openalex.org/W2386983130","https://openalex.org/W2361243256","https://openalex.org/W2384364391","https://openalex.org/W2362741402","https://openalex.org/W2357614428","https://openalex.org/W3024031591","https://openalex.org/W2051780902"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}