{"id":"https://openalex.org/W2007019461","doi":"https://doi.org/10.1185/03007997609109293","title":"Intravenous fusidic acid ('Fucidin') in the management of severe staphylococcal infections: a review of 46 cases","display_name":"Intravenous fusidic acid ('Fucidin') in the management of severe staphylococcal infections: a review of 46 cases","publication_year":1976,"publication_date":"1976-01-01","ids":{"openalex":"https://openalex.org/W2007019461","doi":"https://doi.org/10.1185/03007997609109293","mag":"2007019461","pmid":"https://pubmed.ncbi.nlm.nih.gov/1277881"},"language":"en","primary_location":{"id":"doi:10.1185/03007997609109293","doi":"https://doi.org/10.1185/03007997609109293","is_oa":false,"landing_page_url":"https://doi.org/10.1185/03007997609109293","pdf_url":null,"source":{"id":"https://openalex.org/S206643269","display_name":"Current Medical Research and Opinion","issn_l":"0300-7995","issn":["0300-7995","1473-4877"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medical Research and Opinion","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027271021","display_name":"A. P. Menday","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. P. Menday","raw_affiliation_strings":["Medical Department, Leo Laboratories Limited, Hayes, Middlesex, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Department, Leo Laboratories Limited, Hayes, Middlesex, England","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029198785","display_name":"B. T. Marsh","orcid":"https://orcid.org/0000-0002-9105-6207","observed_orcids":["https://orcid.org/0000-0002-9105-6207"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. T. Marsh","raw_affiliation_strings":["Medical Department, Leo Laboratories Limited, Hayes, Middlesex, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Department, Leo Laboratories Limited, Hayes, Middlesex, England","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7386,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.71937964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"4","issue":"2","first_page":"132","last_page":"138"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12297","display_name":"Otolaryngology and Infectious Diseases","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fusidic-acid","display_name":"fusidic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intravenous-antibiotics","display_name":"intravenous antibiotics","score":0.7139999866485596},{"id":"https://openalex.org/keywords/staphylococcal-infections","display_name":"staphylococcal infections","score":0.8989999890327454},{"id":"https://openalex.org/keywords/serious-bacterial-infection","display_name":"serious bacterial infection","score":0.6970000267028809},{"id":"https://openalex.org/keywords/survival-outcomes","display_name":"survival outcomes","score":0.5440000295639038},{"id":"https://openalex.org/keywords/prior-antibiotic-use","display_name":"prior antibiotic use","score":0.7360000014305115},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.890999972820282}],"concepts":[{"id":"https://openalex.org/C2780483375","wikidata":"https://www.wikidata.org/wiki/Q259930","display_name":"Fusidic acid","level":4,"score":0.9962142705917358},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9482629895210266},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.7393419742584229},{"id":"https://openalex.org/C2777334864","wikidata":"https://www.wikidata.org/wiki/Q34879","display_name":"Staphylococcal infections","level":4,"score":0.5775462985038757},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.5314017534255981},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5085076093673706},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4085426926612854},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3965596556663513},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.16545361280441284},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.10002142190933228},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005672","descriptor_name":"Fusidic Acid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005672","descriptor_name":"Fusidic Acid","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005672","descriptor_name":"Fusidic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1185/03007997609109293","doi":"https://doi.org/10.1185/03007997609109293","is_oa":false,"landing_page_url":"https://doi.org/10.1185/03007997609109293","pdf_url":null,"source":{"id":"https://openalex.org/S206643269","display_name":"Current Medical Research and Opinion","issn_l":"0300-7995","issn":["0300-7995","1473-4877"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medical Research and Opinion","raw_type":"journal-article"},{"id":"pmid:1277881","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1277881","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current medical research and opinion","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W205848623","https://openalex.org/W1964871687","https://openalex.org/W1977206449","https://openalex.org/W1979155979","https://openalex.org/W2033919936","https://openalex.org/W2057984201","https://openalex.org/W2070432533","https://openalex.org/W2078270964","https://openalex.org/W2113338695","https://openalex.org/W2157390886","https://openalex.org/W2186245848","https://openalex.org/W2253524957","https://openalex.org/W2258449870","https://openalex.org/W2332586517","https://openalex.org/W2395506158","https://openalex.org/W2416028300","https://openalex.org/W4360587339","https://openalex.org/W4360970961"],"related_works":["https://openalex.org/W2034789639","https://openalex.org/W4360587339","https://openalex.org/W2431509311","https://openalex.org/W2400001374","https://openalex.org/W2413912452","https://openalex.org/W2386985720","https://openalex.org/W2367240979","https://openalex.org/W2413328779","https://openalex.org/W1994548983","https://openalex.org/W2165302829"],"abstract_inverted_index":{"Case":[0],"reports":[1],"are":[2],"reviewed":[3],"of":[4,29,34,50,92],"46":[5],"patients":[6,23,41],"with":[7,16,37],"severe,":[8],"life-threatening":[9],"infections,":[10,68],"mainly":[11],"staphylococcal,":[12],"who":[13],"were":[14],"treated":[15],"intravenous":[17,81],"fusidic":[18,38,51,82],"acid.":[19,39,52],"Overall,":[20],"22":[21],"(48%)":[22],"survived":[24],"and":[25],"24":[26,32],"died,":[27],"10":[28],"these":[30],"within":[31],"hours":[33],"commencing":[35],"treatment":[36,61,91],"Thirty-nine":[40],"received":[42],"unsuccessful":[43],"antibiotic":[44,60],"therapy":[45],"prior":[46,59],"to":[47,57,62],"the":[48,90],"administration":[49],"It":[53,77],"was":[54],"not":[55],"possible":[56],"relate":[58],"outcome,":[63],"and,":[64],"in":[65,89],"such":[66],"severe":[67,93],"complicating":[69],"diseases":[70],"had":[71],"an":[72,86],"adverse":[73],"effect":[74],"upon":[75],"survival.":[76],"is":[78],"concluded":[79],"that":[80],"acid":[83],"('Fucidin')":[84],"has":[85],"important":[87],"place":[88],"staphylococcal":[94],"infections.":[95]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}