{"id":"https://openalex.org/W2006928007","doi":"https://doi.org/10.1046/j.1525-1594.2001.06770.x","title":"The HeartMate II: Design and Development of a Fully Sealed Axial Flow Left Ventricular Assist System","display_name":"The HeartMate II: Design and Development of a Fully Sealed Axial Flow Left Ventricular Assist System","publication_year":2001,"publication_date":"2001-05-01","ids":{"openalex":"https://openalex.org/W2006928007","doi":"https://doi.org/10.1046/j.1525-1594.2001.06770.x","mag":"2006928007","pmid":"https://pubmed.ncbi.nlm.nih.gov/11403668"},"language":"en","primary_location":{"id":"doi:10.1046/j.1525-1594.2001.06770.x","doi":"https://doi.org/10.1046/j.1525-1594.2001.06770.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1525-1594.2001.06770.x","pdf_url":null,"source":{"id":"https://openalex.org/S40391745","display_name":"Artificial Organs","issn_l":"0160-564X","issn":["0160-564X","1525-1594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Organs","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"David J. Burke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David J. Burke","raw_affiliation_strings":["Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts, USA. david.burke@thoratec.com","Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts, USA. david.burke@thoratec.com","institution_ids":["https://openalex.org/I924680084"]},{"raw_affiliation_string":"Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Edward Burke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward Burke","raw_affiliation_strings":["Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030598837","display_name":"Farzad Parsaie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farzad Parsaie","raw_affiliation_strings":["Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108517282","display_name":"Victor L. Poirier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victor Poirier","raw_affiliation_strings":["Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thermo Cardiosystems Inc. (now Thoratec Corp.), Woburn, Massachusetts; and","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109151927","display_name":"KENNETH C. BUTLER","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Butler","raw_affiliation_strings":["Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Douglas Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Douglas Thomas","raw_affiliation_strings":["Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111578596","display_name":"LYNN P. TAYLOR","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lynn Taylor","raw_affiliation_strings":["Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A","institution_ids":["https://openalex.org/I924680084"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055228945","display_name":"Timothy Richard Maher","orcid":"https://orcid.org/0000-0003-0019-3415","observed_orcids":["https://orcid.org/0000-0003-0019-3415"]},"institutions":[{"id":"https://openalex.org/I924680084","display_name":"Thoratec Corporation (United States)","ror":"https://ror.org/051jtz490","country_code":"US","type":"company","lineage":["https://openalex.org/I924680084"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Maher","raw_affiliation_strings":["Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nimbus Inc. (now Thoratec Corp.), Rancho Cordova, California, U.S.A","institution_ids":["https://openalex.org/I924680084"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I924680084"],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":null,"fwci":2.505,"has_fulltext":false,"cited_by_count":76,"citation_normalized_percentile":{"value":0.89685956,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"25","issue":"5","first_page":"380","last_page":"385"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11249","display_name":"Wireless Power Transfer Systems","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heartmate-ii","display_name":"HeartMate II","score":0.9319999814033508},{"id":"https://openalex.org/keywords/left-ventricular-assist-device","display_name":"left ventricular assist device","score":0.9819999933242798},{"id":"https://openalex.org/keywords/axial-flow-blood-pump","display_name":"axial flow blood pump","score":0.8159999847412109},{"id":"https://openalex.org/keywords/transcutaneous-energy-transfer","display_name":"transcutaneous energy transmission","score":0.9020000100135803},{"id":"https://openalex.org/keywords/radio-telemetry","display_name":"radio telemetry","score":0.9440000057220459}],"concepts":[{"id":"https://openalex.org/C138331895","wikidata":"https://www.wikidata.org/wiki/Q11650","display_name":"Electronics","level":2,"score":0.6669188737869263},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.5814335346221924},{"id":"https://openalex.org/C555008776","wikidata":"https://www.wikidata.org/wiki/Q267298","display_name":"Battery (electricity)","level":3,"score":0.5766770243644714},{"id":"https://openalex.org/C30403606","wikidata":"https://www.wikidata.org/wiki/Q2981904","display_name":"Electromagnetic coil","level":2,"score":0.5491450428962708},{"id":"https://openalex.org/C183121708","wikidata":"https://www.wikidata.org/wiki/Q209867","display_name":"Telemetry","level":2,"score":0.5153750777244568},{"id":"https://openalex.org/C50942859","wikidata":"https://www.wikidata.org/wiki/Q4967193","display_name":"Rectification","level":3,"score":0.48902544379234314},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.44346532225608826},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.40703830122947693},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.40620991587638855},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.392295241355896},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3470781445503235},{"id":"https://openalex.org/C171146098","wikidata":"https://www.wikidata.org/wiki/Q124192","display_name":"Automotive engineering","level":1,"score":0.3253647983074188},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.1948932409286499},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011211","descriptor_name":"Electric Power Supplies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011474","descriptor_name":"Prosthesis Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013686","descriptor_name":"Telemetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1525-1594.2001.06770.x","doi":"https://doi.org/10.1046/j.1525-1594.2001.06770.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1525-1594.2001.06770.x","pdf_url":null,"source":{"id":"https://openalex.org/S40391745","display_name":"Artificial Organs","issn_l":"0160-564X","issn":["0160-564X","1525-1594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Organs","raw_type":"journal-article"},{"id":"pmid:11403668","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11403668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial organs","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.766700029373169,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/9","score":0.4943999946117401,"display_name":"Industry, innovation and infrastructure"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1996665722","https://openalex.org/W2052289555","https://openalex.org/W2079362473","https://openalex.org/W2167742249","https://openalex.org/W2401613231","https://openalex.org/W4229968395"],"related_works":["https://openalex.org/W1994505274","https://openalex.org/W2021984391","https://openalex.org/W8094210","https://openalex.org/W2394828321","https://openalex.org/W4236049313","https://openalex.org/W4416172692","https://openalex.org/W2069750792","https://openalex.org/W2024753971","https://openalex.org/W3152298511","https://openalex.org/W1986151320"],"abstract_inverted_index":{"Our":[0],"group":[1],"is":[2],"developing":[3],"the":[4,25,38,45,61,74,114],"control":[5,79],"and":[6,15,56,78,122,131],"power":[7],"transmission":[8,48],"components":[9,107],"required":[10],"to":[11,51,96,108,117,127,132],"implement":[12],"a":[13,41,53,64,70,123],"permanent":[14],"fully":[16],"sealed":[17,66],"left":[18],"ventricular":[19],"assist":[20],"system":[21,49],"(LVAS).":[22],"Starting":[23],"with":[24,81],"percutaneously":[26],"powered":[27],"HeartMate":[28],"II":[29],"blood":[30],"pump,":[31],"our":[32],"development":[33],"efforts":[34],"are":[35],"focused":[36],"in":[37,113],"following":[39],"areas:":[40],"complete":[42],"redesign":[43],"of":[44,73,93,99,136],"transcutaneous":[46],"energy":[47],"(TETS)":[50],"include":[52],"rectification":[54],"network":[55],"autonomous":[57],"voltage":[58],"regulation":[59],"within":[60],"secondary":[62],"coil,":[63],"hermetically":[65],"electronics":[67,80],"package":[68],"containing":[69],"miniaturized":[71],"implementation":[72],"existing":[75],"redundant":[76],"drive":[77],"several":[82],"power-input":[83],"options,":[84],"an":[85],"implanted":[86],"rechargeable":[87],"lithium":[88],"ion":[89],"battery":[90],"pack":[91],"capable":[92],"providing":[94],"up":[95],"1":[97],"h":[98],"untethered":[100],"operation,":[101],"implantable":[102],"electrical":[103],"connectors":[104],"that":[105],"allow":[106],"be":[109,118],"connected":[110],"after":[111],"placement":[112],"body":[115],"or":[116],"replaced":[119],"if":[120],"needed,":[121],"radio":[124],"telemetry":[125],"subsystem":[126],"transmit":[128],"diagnostic":[129],"information":[130],"permit":[133],"remote":[134],"adjustment":[135],"selected":[137],"parameters.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}