{"id":"https://openalex.org/W2006604151","doi":"https://doi.org/10.1111/j.1747-0285.2008.00760.x","title":"The Race for Chemical and Biological Space: Drug Discovery and Innovative Technologies","display_name":"The Race for Chemical and Biological Space: Drug Discovery and Innovative Technologies","publication_year":2008,"publication_date":"2008-12-18","ids":{"openalex":"https://openalex.org/W2006604151","doi":"https://doi.org/10.1111/j.1747-0285.2008.00760.x","mag":"2006604151","pmid":"https://pubmed.ncbi.nlm.nih.gov/19152628"},"language":"en","primary_location":{"id":"doi:10.1111/j.1747-0285.2008.00760.x","doi":"https://doi.org/10.1111/j.1747-0285.2008.00760.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1747-0285.2008.00760.x","pdf_url":null,"source":{"id":"https://openalex.org/S123587420","display_name":"Chemical Biology & Drug Design","issn_l":"1747-0277","issn":["1747-0277","1747-0285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Biology & Drug Design","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113494503","display_name":"Tomi K. Sawyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]},{"id":"https://openalex.org/I24603500","display_name":"University of Massachusetts Amherst","ror":"https://ror.org/0072zz521","country_code":"US","type":"education","lineage":["https://openalex.org/I24603500"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tomi K. Sawyer","raw_affiliation_strings":["Editor-in-Chief, Chemical Biology & Drug DesignChief Scientific Officer and Senior Vice-President,Drug Discovery and Innovative Technologies,Aileron Therapeutics, Cambridge, Massachusetts, USAAdjunct Professor, Department of Chemistry,University of Massachusetts, Amherst, Massachusetts, USAAdjunct Professor, Biochemistry & Molecular BiologyUniversity of Massachusetts, Amherst, Massachusetts, USAAdjunct Professor, Department of Cancer Biology,University of Massachusetts Medical School, Worcester, Massachusetts, USAAdjunct Professor, Center for Drug Discovery,Northeastern University, Boston, Massachusetts, USAOrganizing Chair, World Project for Chemical Biology and Drug Design","University of Massachusetts Chan Medical School, Worcester, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Editor-in-Chief, Chemical Biology & Drug DesignChief Scientific Officer and Senior Vice-President,Drug Discovery and Innovative Technologies,Aileron Therapeutics, Cambridge, Massachusetts, USAAdjunct Professor, Department of Chemistry,University of Massachusetts, Amherst, Massachusetts, USAAdjunct Professor, Biochemistry & Molecular BiologyUniversity of Massachusetts, Amherst, Massachusetts, USAAdjunct Professor, Department of Cancer Biology,University of Massachusetts Medical School, Worcester, Massachusetts, USAAdjunct Professor, Center for Drug Discovery,Northeastern University, Boston, Massachusetts, USAOrganizing Chair, World Project for Chemical Biology and Drug Design","institution_ids":["https://openalex.org/I12912129","https://openalex.org/I166722992","https://openalex.org/I24603500"]},{"raw_affiliation_string":"University of Massachusetts Chan Medical School, Worcester, United States","institution_ids":["https://openalex.org/I166722992"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5113494503"],"corresponding_institution_ids":["https://openalex.org/I12912129","https://openalex.org/I166722992","https://openalex.org/I24603500"],"apc_list":{"value":3920,"currency":"USD","value_usd":3920},"apc_paid":null,"fwci":0.4328,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.69950036,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"73","issue":"1","first_page":"1","last_page":"2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13656","display_name":"Science, Research, and Medicine","score":0.08299999684095383,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.034299999475479126,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemical-space","display_name":"chemical space","score":0.7649999856948853},{"id":"https://openalex.org/keywords/biological-space","display_name":"biological space","score":0.9909999966621399},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":0.9800000190734863},{"id":"https://openalex.org/keywords/innovative-technologies","display_name":"innovative technologies","score":0.8009999990463257},{"id":"https://openalex.org/keywords/chemical-biology","display_name":"chemical biology","score":0.4449999928474426},{"id":"https://openalex.org/keywords/drug-design","display_name":"drug design","score":0.5759999752044678}],"concepts":[{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.5611943602561951},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.44021496176719666},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3233488202095032},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2343447208404541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1865694522857666},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.15743288397789001}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1747-0285.2008.00760.x","doi":"https://doi.org/10.1111/j.1747-0285.2008.00760.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1747-0285.2008.00760.x","pdf_url":null,"source":{"id":"https://openalex.org/S123587420","display_name":"Chemical Biology & Drug Design","issn_l":"1747-0277","issn":["1747-0277","1747-0285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Biology & Drug Design","raw_type":"journal-article"},{"id":"pmid:19152628","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19152628","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical biology & drug design","raw_type":"Editorial"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.46000000834465027,"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W20514746","https://openalex.org/W41967644","https://openalex.org/W78991851","https://openalex.org/W1968682237","https://openalex.org/W1971209239","https://openalex.org/W1972821149","https://openalex.org/W1972888570","https://openalex.org/W1993496775","https://openalex.org/W2003966981","https://openalex.org/W2008059340","https://openalex.org/W2033591223","https://openalex.org/W2058799364","https://openalex.org/W2079311372","https://openalex.org/W2087359404","https://openalex.org/W2095417103","https://openalex.org/W2096864392","https://openalex.org/W2120973253","https://openalex.org/W2153838454","https://openalex.org/W2154939550","https://openalex.org/W2169408159","https://openalex.org/W2397769844","https://openalex.org/W2472350536"],"related_works":["https://openalex.org/W2480711475","https://openalex.org/W2061997414","https://openalex.org/W1587522533","https://openalex.org/W1996411829","https://openalex.org/W1984523482","https://openalex.org/W2121182182","https://openalex.org/W2791017844","https://openalex.org/W2092688629","https://openalex.org/W2044905153","https://openalex.org/W2561730314"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}