{"id":"https://openalex.org/W2006497840","doi":"https://doi.org/10.1016/0272-6386(95)90450-6","title":"Effects of recombinant human insulin-like growth factor 1 on renal handling of phosphorus, calcium, and sodium in normal humans","display_name":"Effects of recombinant human insulin-like growth factor 1 on renal handling of phosphorus, calcium, and sodium in normal humans","publication_year":1995,"publication_date":"1995-11-01","ids":{"openalex":"https://openalex.org/W2006497840","doi":"https://doi.org/10.1016/0272-6386(95)90450-6","mag":"2006497840","pmid":"https://pubmed.ncbi.nlm.nih.gov/7485139"},"language":"en","primary_location":{"id":"doi:10.1016/0272-6386(95)90450-6","doi":"https://doi.org/10.1016/0272-6386(95)90450-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0272-6386(95)90450-6","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050491175","display_name":"Joel D. Kopple","orcid":"https://orcid.org/0000-0003-0193-9696","observed_orcids":["https://orcid.org/0000-0003-0193-9696"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel D. Kopple","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center, Torrance 90509, USA","Department of Medicine, Harbor-UCLA Medical Center Torrance, CA, USA","UCLA Schools of Medicine and Public Health, Torrance, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center, Torrance 90509, USA","institution_ids":["https://openalex.org/I4210165985"]},{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center Torrance, CA, USA","institution_ids":["https://openalex.org/I4210165985"]},{"raw_affiliation_string":"UCLA Schools of Medicine and Public Health, Torrance, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045416081","display_name":"Hu Ding","orcid":"https://orcid.org/0000-0002-1814-1552","observed_orcids":["https://orcid.org/0000-0002-1814-1552"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hu Ding","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center Torrance, CA, USA","UCLA Schools of Medicine and Public Health, Torrance, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center Torrance, CA, USA","institution_ids":["https://openalex.org/I4210165985"]},{"raw_affiliation_string":"UCLA Schools of Medicine and Public Health, Torrance, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089452946","display_name":"Raimund R. Hirschberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raimund Hirschberg","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center Torrance, CA, USA","UCLA Schools of Medicine and Public Health, Torrance, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center Torrance, CA, USA","institution_ids":["https://openalex.org/I4210165985"]},{"raw_affiliation_string":"UCLA Schools of Medicine and Public Health, Torrance, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.263,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.54883676,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"26","issue":"5","first_page":"818","last_page":"824"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.0430000014603138,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12840","display_name":"Renal function and acid-base balance","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.9739999771118164},{"id":"https://openalex.org/keywords/recombinant-human-igf-1","display_name":"recombinant human IGF-1","score":0.9620000123977661},{"id":"https://openalex.org/keywords/urinary-calcium-excretion","display_name":"urinary calcium excretion","score":0.7409999966621399},{"id":"https://openalex.org/keywords/fractional-excretion-of-calcium","display_name":"fractional excretion of calcium","score":0.8169999718666077},{"id":"https://openalex.org/keywords/sodium-excretion","display_name":"sodium excretion","score":0.8799999952316284},{"id":"https://openalex.org/keywords/fractional-excretion-of-sodium","display_name":"fractional excretion of sodium","score":0.7670000195503235},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.718999981880188},{"id":"https://openalex.org/keywords/serum-electrolytes","display_name":"serum electrolytes","score":0.6320000290870667},{"id":"https://openalex.org/keywords/glucose-infusion","display_name":"glucose infusion","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.834725022315979},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7884305119514465},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7662000060081482},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.740488588809967},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6997447609901428},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6427296996116638},{"id":"https://openalex.org/C510538283","wikidata":"https://www.wikidata.org/wiki/Q674","display_name":"Phosphorus","level":2,"score":0.5900381803512573},{"id":"https://openalex.org/C2780018836","wikidata":"https://www.wikidata.org/wiki/Q7900635","display_name":"Urine sodium","level":3,"score":0.5790154933929443},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.5733950138092041},{"id":"https://openalex.org/C2780343553","wikidata":"https://www.wikidata.org/wiki/Q1440574","display_name":"Fractional excretion of sodium","level":3,"score":0.4792449474334717},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2207336127758026},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010758","descriptor_name":"Phosphorus","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0272-6386(95)90450-6","doi":"https://doi.org/10.1016/0272-6386(95)90450-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0272-6386(95)90450-6","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},{"id":"pmid:7485139","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7485139","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G310026855","display_name":null,"funder_award_id":"RR00425","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G7595554470","display_name":"General Clinical Research Center","funder_award_id":"M01RR000425","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320306445","display_name":"National Kidney Foundation","ror":null},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1547288863","https://openalex.org/W1908551723","https://openalex.org/W1966917914","https://openalex.org/W1967726314","https://openalex.org/W1969121572","https://openalex.org/W1971162897","https://openalex.org/W1974238838","https://openalex.org/W1976649572","https://openalex.org/W1988243733","https://openalex.org/W1990967695","https://openalex.org/W1994699544","https://openalex.org/W1994992670","https://openalex.org/W1999801514","https://openalex.org/W2017698787","https://openalex.org/W2029057822","https://openalex.org/W2030382773","https://openalex.org/W2034921111","https://openalex.org/W2037887467","https://openalex.org/W2054548024","https://openalex.org/W2069708059","https://openalex.org/W2072564657","https://openalex.org/W2077631644","https://openalex.org/W2081047941","https://openalex.org/W2094757480","https://openalex.org/W2102123572","https://openalex.org/W2125291250","https://openalex.org/W2139666748","https://openalex.org/W2145349151","https://openalex.org/W2158632654","https://openalex.org/W2317515869","https://openalex.org/W2407284180","https://openalex.org/W2419622771","https://openalex.org/W3134942565","https://openalex.org/W4242920673","https://openalex.org/W6658983162"],"related_works":["https://openalex.org/W2037887467","https://openalex.org/W2030382773","https://openalex.org/W2412224998","https://openalex.org/W1964891036","https://openalex.org/W2024067973","https://openalex.org/W2416435233","https://openalex.org/W2018757284","https://openalex.org/W2043536141","https://openalex.org/W2034835366","https://openalex.org/W1978979499"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}