{"id":"https://openalex.org/W2006460892","doi":"https://doi.org/10.1016/j.drudis.2014.05.002","title":"Chemical approaches to targeting drug resistance in cancer stem cells","display_name":"Chemical approaches to targeting drug resistance in cancer stem cells","publication_year":2014,"publication_date":"2014-05-10","ids":{"openalex":"https://openalex.org/W2006460892","doi":"https://doi.org/10.1016/j.drudis.2014.05.002","mag":"2006460892","pmid":"https://pubmed.ncbi.nlm.nih.gov/24819719"},"language":"en","primary_location":{"id":"doi:10.1016/j.drudis.2014.05.002","doi":"https://doi.org/10.1016/j.drudis.2014.05.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.drudis.2014.05.002","pdf_url":null,"source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5115600877","display_name":"Panagiota A. Sotiropoulou","orcid":"https://orcid.org/0000-0002-0213-7110","observed_orcids":["https://orcid.org/0000-0002-0213-7110"]},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Panagiota A. Sotiropoulou","raw_affiliation_strings":["Interdisciplinary Research Institute (IRIBHM), Universit\u00e9 Libre de Bruxelles (ULB), 808 route de Lennik, BatC, 1070 Bruxelles, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-0213-7110","affiliations":[{"raw_affiliation_string":"Interdisciplinary Research Institute (IRIBHM), Universit\u00e9 Libre de Bruxelles (ULB), 808 route de Lennik, BatC, 1070 Bruxelles, Belgium","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042642061","display_name":"Michael S. Christodoulou","orcid":"https://orcid.org/0000-0002-5098-3143","observed_orcids":["https://orcid.org/0000-0002-5098-3143"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michael S. Christodoulou","raw_affiliation_strings":["Dipartimento di Chimica, Universit\u00e0 degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Chimica, Universit\u00e0 degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026068230","display_name":"Alessandra Silvani","orcid":"https://orcid.org/0000-0002-0397-2636","observed_orcids":["https://orcid.org/0000-0002-0397-2636"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandra Silvani","raw_affiliation_strings":["Dipartimento di Chimica, Universit\u00e0 degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy"],"raw_orcid":"https://orcid.org/0000-0002-0397-2636","affiliations":[{"raw_affiliation_string":"Dipartimento di Chimica, Universit\u00e0 degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025477516","display_name":"Christel C. Herold\u2010Mende","orcid":"https://orcid.org/0000-0002-1915-745X","observed_orcids":["https://orcid.org/0000-0002-1915-745X"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christel Herold-Mende","raw_affiliation_strings":["Division of Experimental Neurosurgery, Department of Neurosurgery, Ruprecht-Karls-Universit\u00e4t Heidelberg, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Experimental Neurosurgery, Department of Neurosurgery, Ruprecht-Karls-Universit\u00e4t Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051114446","display_name":"Daniele Passarella","orcid":"https://orcid.org/0000-0001-6180-9581","observed_orcids":["https://orcid.org/0000-0001-6180-9581"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Daniele Passarella","raw_affiliation_strings":["Dipartimento di Chimica, Universit\u00e0 degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy. Electronic address: daniele.passarella@unimi.it","Dipartimento di Chimica; Universit\u00e0 degli Studi di Milano; via Golgi 19 20133 Milano Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Chimica, Universit\u00e0 degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy. Electronic address: daniele.passarella@unimi.it","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Dipartimento di Chimica; Universit\u00e0 degli Studi di Milano; via Golgi 19 20133 Milano Italy","institution_ids":["https://openalex.org/I189158943"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5051114446"],"corresponding_institution_ids":["https://openalex.org/I189158943"],"apc_list":{"value":4720,"currency":"USD","value_usd":4720},"apc_paid":null,"fwci":1.9757,"has_fulltext":false,"cited_by_count":101,"citation_normalized_percentile":{"value":0.89274052,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"19","issue":"10","first_page":"1547","last_page":"1562"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-stem-cells","display_name":"cancer stem cells","score":1.0},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.8270000219345093},{"id":"https://openalex.org/keywords/chemosensitization","display_name":"chemosensitization","score":0.621999979019165},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.6899999976158142},{"id":"https://openalex.org/keywords/natural-compounds","display_name":"natural compounds","score":0.4869999885559082},{"id":"https://openalex.org/keywords/synthetic-chemicals","display_name":"synthetic compounds","score":0.9850000143051147},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.609000027179718},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.3959999978542328}],"concepts":[{"id":"https://openalex.org/C117262875","wikidata":"https://www.wikidata.org/wiki/Q5135057","display_name":"Clonogenic assay","level":3,"score":0.7799264192581177},{"id":"https://openalex.org/C55427017","wikidata":"https://www.wikidata.org/wiki/Q1638475","display_name":"Cancer stem cell","level":3,"score":0.7338202595710754},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.615036129951477},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.515596330165863},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5135067105293274},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.506351113319397},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.49334827065467834},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47761815786361694},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.45478925108909607},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39410918951034546},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3255324959754944},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.26076287031173706},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.23485586047172546},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14459675550460815},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.10638150572776794},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08338716626167297}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.drudis.2014.05.002","doi":"https://doi.org/10.1016/j.drudis.2014.05.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.drudis.2014.05.002","pdf_url":null,"source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},{"id":"pmid:24819719","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24819719","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug discovery today","raw_type":"Journal Article"},{"id":"pmh:oai:dipot.ulb.ac.be:2013/187940","doi":null,"is_oa":false,"landing_page_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/187940/1/Elsevier_171567.pdf","pdf_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/187940/1/Elsevier_171567.pdf","source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Drug discovery today, 19 (10","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":175,"referenced_works":["https://openalex.org/W109776568","https://openalex.org/W336378862","https://openalex.org/W1695417215","https://openalex.org/W1739249602","https://openalex.org/W1793887838","https://openalex.org/W1902577542","https://openalex.org/W1964427001","https://openalex.org/W1965747780","https://openalex.org/W1965810575","https://openalex.org/W1967402893","https://openalex.org/W1967578658","https://openalex.org/W1968643486","https://openalex.org/W1970230381","https://openalex.org/W1973199129","https://openalex.org/W1976550785","https://openalex.org/W1980855246","https://openalex.org/W1981534871","https://openalex.org/W1982649435","https://openalex.org/W1983357205","https://openalex.org/W1983791607","https://openalex.org/W1984564310","https://openalex.org/W1986679409","https://openalex.org/W1987678124","https://openalex.org/W1989414412","https://openalex.org/W1992381541","https://openalex.org/W1992945290","https://openalex.org/W1996588332","https://openalex.org/W1996830477","https://openalex.org/W1998708832","https://openalex.org/W1998728654","https://openalex.org/W1998794592","https://openalex.org/W1999306559","https://openalex.org/W2002435343","https://openalex.org/W2004211520","https://openalex.org/W2004419844","https://openalex.org/W2004821524","https://openalex.org/W2005231191","https://openalex.org/W2006307101","https://openalex.org/W2006434892","https://openalex.org/W2007109655","https://openalex.org/W2007255793","https://openalex.org/W2007369931","https://openalex.org/W2007978249","https://openalex.org/W2008720321","https://openalex.org/W2008878539","https://openalex.org/W2010088940","https://openalex.org/W2011279915","https://openalex.org/W2012152282","https://openalex.org/W2012619882","https://openalex.org/W2014189145","https://openalex.org/W2015303096","https://openalex.org/W2018360235","https://openalex.org/W2019276374","https://openalex.org/W2020692309","https://openalex.org/W2022442325","https://openalex.org/W2022896276","https://openalex.org/W2023316892","https://openalex.org/W2024145520","https://openalex.org/W2024430424","https://openalex.org/W2026064767","https://openalex.org/W2027228949","https://openalex.org/W2027327214","https://openalex.org/W2029443168","https://openalex.org/W2031348772","https://openalex.org/W2033061169","https://openalex.org/W2033071625","https://openalex.org/W2035402593","https://openalex.org/W2039035199","https://openalex.org/W2039075677","https://openalex.org/W2039124133","https://openalex.org/W2039442869","https://openalex.org/W2040919299","https://openalex.org/W2044166564","https://openalex.org/W2044858560","https://openalex.org/W2045208621","https://openalex.org/W2045318349","https://openalex.org/W2045923231","https://openalex.org/W2046483038","https://openalex.org/W2046651696","https://openalex.org/W2047339299","https://openalex.org/W2047674690","https://openalex.org/W2049589513","https://openalex.org/W2050314336","https://openalex.org/W2050406835","https://openalex.org/W2051011734","https://openalex.org/W2051413562","https://openalex.org/W2051870121","https://openalex.org/W2056461865","https://openalex.org/W2058494666","https://openalex.org/W2058569154","https://openalex.org/W2060469321","https://openalex.org/W2060551076","https://openalex.org/W2062366556","https://openalex.org/W2068181025","https://openalex.org/W2068889110","https://openalex.org/W2069224399","https://openalex.org/W2069284062","https://openalex.org/W2069831652","https://openalex.org/W2071392290","https://openalex.org/W2071534620","https://openalex.org/W2073483289","https://openalex.org/W2074513114","https://openalex.org/W2074694798","https://openalex.org/W2074956041","https://openalex.org/W2075294845","https://openalex.org/W2078164390","https://openalex.org/W2078510083","https://openalex.org/W2081685326","https://openalex.org/W2081748846","https://openalex.org/W2082210456","https://openalex.org/W2083274861","https://openalex.org/W2083945212","https://openalex.org/W2085882818","https://openalex.org/W2086486581","https://openalex.org/W2092296376","https://openalex.org/W2093934785","https://openalex.org/W2098712825","https://openalex.org/W2103394810","https://openalex.org/W2104385481","https://openalex.org/W2105823026","https://openalex.org/W2106675906","https://openalex.org/W2107235563","https://openalex.org/W2107400278","https://openalex.org/W2107461722","https://openalex.org/W2107591555","https://openalex.org/W2108835820","https://openalex.org/W2110034822","https://openalex.org/W2113089439","https://openalex.org/W2114765209","https://openalex.org/W2116394959","https://openalex.org/W2116975015","https://openalex.org/W2119348664","https://openalex.org/W2120656656","https://openalex.org/W2120932387","https://openalex.org/W2122891169","https://openalex.org/W2124111260","https://openalex.org/W2129929326","https://openalex.org/W2130251290","https://openalex.org/W2133117291","https://openalex.org/W2134123270","https://openalex.org/W2136544912","https://openalex.org/W2138050607","https://openalex.org/W2140152239","https://openalex.org/W2140657777","https://openalex.org/W2140987848","https://openalex.org/W2141184407","https://openalex.org/W2142647376","https://openalex.org/W2144444064","https://openalex.org/W2144677406","https://openalex.org/W2145044290","https://openalex.org/W2146447952","https://openalex.org/W2147516356","https://openalex.org/W2147631083","https://openalex.org/W2151103319","https://openalex.org/W2152939397","https://openalex.org/W2153899496","https://openalex.org/W2154033106","https://openalex.org/W2154857845","https://openalex.org/W2158627893","https://openalex.org/W2161333480","https://openalex.org/W2162922734","https://openalex.org/W2163932764","https://openalex.org/W2164601967","https://openalex.org/W2165244997","https://openalex.org/W2165307476","https://openalex.org/W2165428601","https://openalex.org/W2166089777","https://openalex.org/W2166441970","https://openalex.org/W2167017433","https://openalex.org/W2167414381","https://openalex.org/W2167564369","https://openalex.org/W2169984828","https://openalex.org/W2171223909","https://openalex.org/W2172211289","https://openalex.org/W2344094567"],"related_works":["https://openalex.org/W2953667394","https://openalex.org/W3144308092","https://openalex.org/W4407382936","https://openalex.org/W3175449920","https://openalex.org/W3140658173","https://openalex.org/W4412727549","https://openalex.org/W2887861564","https://openalex.org/W2964191569","https://openalex.org/W2741545625","https://openalex.org/W4367173900"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":18},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}