{"id":"https://openalex.org/W2006346404","doi":"https://doi.org/10.1126/science.278.5339.840","title":"A Porous Silicon-Based Optical Interferometric Biosensor","display_name":"A Porous Silicon-Based Optical Interferometric Biosensor","publication_year":1997,"publication_date":"1997-10-31","ids":{"openalex":"https://openalex.org/W2006346404","doi":"https://doi.org/10.1126/science.278.5339.840","mag":"2006346404","pmid":"https://pubmed.ncbi.nlm.nih.gov/9346478"},"language":"en","primary_location":{"id":"doi:10.1126/science.278.5339.840","doi":"https://doi.org/10.1126/science.278.5339.840","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.278.5339.840","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039215368","display_name":"Victor S.\u2010Y. Lin","orcid":"https://orcid.org/0000-0003-4948-1979","observed_orcids":["https://orcid.org/0000-0003-4948-1979"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victor S.-Y. Lin","raw_affiliation_strings":["K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081462607","display_name":"Kianoush Motesharei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kianoush Motesharei","raw_affiliation_strings":["K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007819567","display_name":"Keiki-Pua S. Dancil","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keiki-Pua S. Dancil","raw_affiliation_strings":["K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059375688","display_name":"Michael J. Sailor","orcid":"https://orcid.org/0000-0002-4809-9826","observed_orcids":["https://orcid.org/0000-0002-4809-9826"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael J. Sailor","raw_affiliation_strings":["K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102709647","display_name":"M. Reza Ghadiri","orcid":"https://orcid.org/0000-0002-5997-9271","observed_orcids":["https://orcid.org/0000-0002-5997-9271"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"M. Reza Ghadiri","raw_affiliation_strings":["K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"K.-P. S. Dancil and M. J. Sailor, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093\u20130358, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"V. S.-Y. Lin, K. Motesharei, M. R. Ghadiri, Departments of Chemistry and Molecular Biology, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059375688","https://openalex.org/A5102709647"],"corresponding_institution_ids":["https://openalex.org/I123431417","https://openalex.org/I36258959"],"apc_list":null,"apc_paid":null,"fwci":16.7329,"has_fulltext":false,"cited_by_count":1303,"citation_normalized_percentile":{"value":0.99645239,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"278","issue":"5339","first_page":"840","last_page":"843"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11169","display_name":"Silicon Nanostructures and Photoluminescence","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11169","display_name":"Silicon Nanostructures and Photoluminescence","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/porous-silicon","display_name":"porous silicon","score":0.9559999704360962},{"id":"https://openalex.org/keywords/optical-biosensors","display_name":"optical biosensors","score":0.9120000004768372},{"id":"https://openalex.org/keywords/interferometric-biosensor","display_name":"interferometric biosensor","score":0.7670000195503235},{"id":"https://openalex.org/keywords/fabry-perot-fringes","display_name":"Fabry-Perot fringes","score":0.890999972820282},{"id":"https://openalex.org/keywords/refractive-index-change","display_name":"refractive index change","score":0.7250000238418579},{"id":"https://openalex.org/keywords/biotin-detection","display_name":"biotin detection","score":0.6830000281333923},{"id":"https://openalex.org/keywords/digoxigenin","display_name":"digoxigenin","score":0.906000018119812},{"id":"https://openalex.org/keywords/streptavidin","display_name":"streptavidin","score":0.9620000123977661},{"id":"https://openalex.org/keywords/antibody-detection","display_name":"antibody detection","score":0.9549999833106995}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.8321622014045715},{"id":"https://openalex.org/C2776685891","wikidata":"https://www.wikidata.org/wiki/Q428660","display_name":"Porous silicon","level":3,"score":0.7941845655441284},{"id":"https://openalex.org/C10390740","wikidata":"https://www.wikidata.org/wiki/Q2282401","display_name":"Analyte","level":2,"score":0.6334523558616638},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6211267113685608},{"id":"https://openalex.org/C42067758","wikidata":"https://www.wikidata.org/wiki/Q174102","display_name":"Refractive index","level":2,"score":0.6121575236320496},{"id":"https://openalex.org/C544956773","wikidata":"https://www.wikidata.org/wiki/Q670","display_name":"Silicon","level":2,"score":0.6100730895996094},{"id":"https://openalex.org/C2776190903","wikidata":"https://www.wikidata.org/wiki/Q421817","display_name":"Streptavidin","level":3,"score":0.5327325463294983},{"id":"https://openalex.org/C166689943","wikidata":"https://www.wikidata.org/wiki/Q850283","display_name":"Interferometry","level":2,"score":0.47969290614128113},{"id":"https://openalex.org/C2776552150","wikidata":"https://www.wikidata.org/wiki/Q420728","display_name":"Digoxigenin","level":5,"score":0.4796195924282074},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.45123156905174255},{"id":"https://openalex.org/C2777735830","wikidata":"https://www.wikidata.org/wiki/Q6507061","display_name":"Molecular binding","level":3,"score":0.4493659734725952},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.3923918604850769},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3224409818649292},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.31250935792922974},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.2999081611633301},{"id":"https://openalex.org/C2778204606","wikidata":"https://www.wikidata.org/wiki/Q181354","display_name":"Biotin","level":2,"score":0.2530266344547272},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.13320070505142212},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C81439078","wikidata":"https://www.wikidata.org/wiki/Q2304142","display_name":"In situ hybridization","level":4,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004076","descriptor_name":"Digoxigenin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007368","descriptor_name":"Interferometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012825","descriptor_name":"Silicon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019809","descriptor_name":"Streptavidin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019921","descriptor_name":"Biotinylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1126/science.278.5339.840","doi":"https://doi.org/10.1126/science.278.5339.840","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.278.5339.840","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},{"id":"pmid:9346478","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9346478","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science (New York, N.Y.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3315979818","display_name":null,"funder_award_id":"2SO6 GM47165-06","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5782327086","display_name":"UNIVERSITY OF CALIFORNIA, SAN DIEGO MBRS PROGRAM","funder_award_id":"S06GM047165","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7172344040","display_name":"DESIGN OF SELF-REPLICATING PEPTIDE BASED ION CHANNELS","funder_award_id":"F32GM018309","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7343243061","display_name":null,"funder_award_id":"GM18309","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W76896458","https://openalex.org/W1965325929","https://openalex.org/W1970156673","https://openalex.org/W1973190514","https://openalex.org/W2002046224","https://openalex.org/W2002986360","https://openalex.org/W2010825429","https://openalex.org/W2024455405","https://openalex.org/W2031859150","https://openalex.org/W2034709140","https://openalex.org/W2034937651","https://openalex.org/W2037509330","https://openalex.org/W2040004408","https://openalex.org/W2046676370","https://openalex.org/W2051664733","https://openalex.org/W2092850986","https://openalex.org/W2138243733","https://openalex.org/W2404983660","https://openalex.org/W4323966236","https://openalex.org/W6634539492"],"related_works":["https://openalex.org/W1771067545","https://openalex.org/W2005484249","https://openalex.org/W2351484629","https://openalex.org/W2322583346","https://openalex.org/W1982973573","https://openalex.org/W2268186938","https://openalex.org/W3198893406","https://openalex.org/W1983120174","https://openalex.org/W2323166371","https://openalex.org/W2787789822"],"abstract_inverted_index":{"A":[0],"biosensor":[1],"has":[2],"been":[3],"developed":[4],"based":[5],"on":[6],"induced":[7,31],"wavelength":[8],"shifts":[9],"in":[10,14,33],"the":[11,15,34,38,46],"Fabry-Perot":[12],"fringes":[13],"visible-light":[16],"reflection":[17],"spectrum":[18],"of":[19,24,29,37,45],"appropriately":[20],"derivatized":[21],"thin":[22],"films":[23],"porous":[25,39],"silicon":[26],"semiconductors.":[27],"Binding":[28],"molecules":[30,53],"changes":[32],"refractive":[35],"index":[36],"silicon.":[40],"The":[41,71],"validity":[42],"and":[43,55,60,63,67,80],"sensitivity":[44],"system":[47],"are":[48],"demonstrated":[49],"for":[50,77],"small":[51],"organic":[52],"(biotin":[54],"digoxigenin),":[56],"16-nucleotide":[57],"DNA":[58],"oligomers,":[59],"proteins":[61],"(streptavidin":[62],"antibodies)":[64],"at":[65],"pico-":[66],"femtomolar":[68],"analyte":[69],"concentrations.":[70],"sensor":[72],"is":[73],"also":[74],"highly":[75],"effective":[76],"detecting":[78],"single":[79],"multilayered":[81],"molecular":[82],"assemblies.":[83]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":39},{"year":2020,"cited_by_count":39},{"year":2019,"cited_by_count":50},{"year":2018,"cited_by_count":49},{"year":2017,"cited_by_count":45},{"year":2016,"cited_by_count":64},{"year":2015,"cited_by_count":69},{"year":2014,"cited_by_count":80},{"year":2013,"cited_by_count":65},{"year":2012,"cited_by_count":74}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}