{"id":"https://openalex.org/W2006271972","doi":"https://doi.org/10.1016/0014-4886(89)90048-4","title":"Parallel development of noradrenergic innervation and cellular compartmentation in the rat spleen","display_name":"Parallel development of noradrenergic innervation and cellular compartmentation in the rat spleen","publication_year":1989,"publication_date":"1989-03-01","ids":{"openalex":"https://openalex.org/W2006271972","doi":"https://doi.org/10.1016/0014-4886(89)90048-4","mag":"2006271972","pmid":"https://pubmed.ncbi.nlm.nih.gov/2920790"},"language":"en","primary_location":{"id":"doi:10.1016/0014-4886(89)90048-4","doi":"https://doi.org/10.1016/0014-4886(89)90048-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0014-4886(89)90048-4","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/0014-4886(89)90048-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110328956","display_name":"Kurt D. Ackerman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kurt D. Ackerman","raw_affiliation_strings":["Department of Neurobiology and Anatomy, University of Rochester, School of Medicine and Dentistry, New York 14642","Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology and Anatomy, University of Rochester, School of Medicine and Dentistry, New York 14642","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084368895","display_name":"Suzanne Y. Felten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne Y. Felten","raw_affiliation_strings":["Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111591911","display_name":"Christine D. Dijkstra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine D. Dijkstra","raw_affiliation_strings":["Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044583574","display_name":"Shmuel Livnat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Shmuel Livnat","raw_affiliation_strings":["Department of Histology, Free University, Amsterdam, The Netherlands","Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology, Free University, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642 USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067518727","display_name":"David L. Felten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"David L. Felten","raw_affiliation_strings":["Department of Histology, Free University, Amsterdam, The Netherlands","Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology, Free University, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]},{"raw_affiliation_string":"Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642 USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":{"value":4110,"currency":"USD","value_usd":4110},"fwci":3.9488,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.95150115,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"103","issue":"3","first_page":"239","last_page":"255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.47119998931884766,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.47119998931884766,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.09669999778270721,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.09480000287294388,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/noradrenergic-innervation","display_name":"noradrenergic innervation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/spleen-development","display_name":"spleen development","score":0.9259999990463257},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.9079999923706055},{"id":"https://openalex.org/keywords/tyrosine-hydroxylase","display_name":"tyrosine hydroxylase","score":0.9879999756813049},{"id":"https://openalex.org/keywords/periarteriolar-lymphoid-sheath","display_name":"periarteriolar lymphoid sheath","score":0.9779999852180481},{"id":"https://openalex.org/keywords/marginal-sinus","display_name":"marginal sinus","score":0.7950000166893005},{"id":"https://openalex.org/keywords/marginal-zone","display_name":"marginal zone","score":0.7950000166893005},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.7590000033378601},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.8899999856948853},{"id":"https://openalex.org/keywords/mhpg","display_name":"MHPG","score":0.8859999775886536},{"id":"https://openalex.org/keywords/splenic-white-pulp","display_name":"splenic white pulp","score":0.6890000104904175},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.6804522275924683},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6584914922714233},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4444934129714966},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44206130504608154},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2166268527507782}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008734","descriptor_name":"Methoxyhydroxyphenylglycol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011916","descriptor_name":"Rats, Inbred F344","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0014-4886(89)90048-4","doi":"https://doi.org/10.1016/0014-4886(89)90048-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0014-4886(89)90048-4","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},{"id":"pmid:2920790","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2920790","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental neurology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/0014-4886(89)90048-4","doi":"https://doi.org/10.1016/0014-4886(89)90048-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0014-4886(89)90048-4","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1657689438","display_name":null,"funder_award_id":"NS-25223","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G181590438","display_name":"NERVE-TARGET INTERACTIONS IN THE DEVELOPING SPLEEN","funder_award_id":"5f31mh009727-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7804730513","display_name":"University of Rochester Medical Scientist Training Program","funder_award_id":"T32GM007356","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8942275450","display_name":null,"funder_award_id":"1 F31 MH09727-01","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W14199799","https://openalex.org/W29671035","https://openalex.org/W79466244","https://openalex.org/W113093683","https://openalex.org/W125766388","https://openalex.org/W137390164","https://openalex.org/W140295565","https://openalex.org/W1521641932","https://openalex.org/W1529606715","https://openalex.org/W1532230742","https://openalex.org/W1956497317","https://openalex.org/W1965997842","https://openalex.org/W1967860016","https://openalex.org/W1969284369","https://openalex.org/W1971283039","https://openalex.org/W1974490301","https://openalex.org/W1982068669","https://openalex.org/W1985249141","https://openalex.org/W2000191410","https://openalex.org/W2004388116","https://openalex.org/W2005884613","https://openalex.org/W2017203343","https://openalex.org/W2019743128","https://openalex.org/W2026439556","https://openalex.org/W2029878362","https://openalex.org/W2032969373","https://openalex.org/W2034802946","https://openalex.org/W2040501389","https://openalex.org/W2044495035","https://openalex.org/W2052445980","https://openalex.org/W2053914684","https://openalex.org/W2054871169","https://openalex.org/W2055117944","https://openalex.org/W2056528694","https://openalex.org/W2056653486","https://openalex.org/W2058404220","https://openalex.org/W2060942917","https://openalex.org/W2062006560","https://openalex.org/W2065153625","https://openalex.org/W2068610695","https://openalex.org/W2070340588","https://openalex.org/W2083471592","https://openalex.org/W2088423551","https://openalex.org/W2089236713","https://openalex.org/W2095351701","https://openalex.org/W2096649095","https://openalex.org/W2101540371","https://openalex.org/W2102121992","https://openalex.org/W2131751913","https://openalex.org/W2137716523","https://openalex.org/W2160310761","https://openalex.org/W2161705840","https://openalex.org/W2171963856","https://openalex.org/W2250148637","https://openalex.org/W2293151363","https://openalex.org/W2395176921","https://openalex.org/W2417063417","https://openalex.org/W3184628723","https://openalex.org/W6629833950"],"related_works":["https://openalex.org/W1971283039","https://openalex.org/W2160310761","https://openalex.org/W2083471592","https://openalex.org/W1982068669","https://openalex.org/W2060942917","https://openalex.org/W139185677","https://openalex.org/W1965748074","https://openalex.org/W1972404518","https://openalex.org/W79466244","https://openalex.org/W2908602576"],"abstract_inverted_index":{"By":[0,178],"combining":[1],"neurochemical":[2],"measurement":[3],"of":[4,26,42,57,79,94,110,166,181,194,223,229,257,270,277,287],"norepinephrine":[5,281],"(NE)":[6],"with":[7,284],"double-label":[8],"immunocytochemistry":[9],"for":[10,282],"tyrosine":[11],"hydroxylase-positive":[12],"(TH+)":[13],"noradrenergic":[14,27,73,230,249,263],"nerves":[15,28],"and":[16,86,91,97,116,132,153,170,290],"specific":[17],"lymphoid":[18,289],"markers,":[19],"we":[20],"have":[21],"examined":[22],"the":[23,30,39,43,54,58,65,69,83,95,99,140,167,175,189,208,220,240,271,274],"developmental":[24],"compartmentation":[25,253],"in":[29,38,202,247,267],"rat":[31],"spleen.":[32],"TH+":[33,159],"nerve":[34,80],"fibers":[35,81,160,231,264],"were":[36,245],"present":[37,266],"white":[40,141],"pulp":[41,142],"spleen":[44,272],"at":[45,53,273],"birth,":[46],"among":[47,89,163],"surface":[48],"IgM-positive":[49],"(sIgM+)":[50],"B":[51,92,217],"lymphocytes":[52,93,165],"outer":[55,149,209],"border":[56],"periarteriolar":[59],"lymphatic":[60],"sheath":[61],"(PALS),":[62],"distant":[63],"from":[64,134,205],"central":[66,84],"artery.":[67],"During":[68],"first":[70],"7":[71],"days,":[72,139,207],"innervation":[74,250],"developed":[75],"rapidly,":[76],"forming":[77],"plexuses":[78],"along":[82,98,174],"artery":[85],"its":[87],"branches,":[88],"T":[90,164],"PALS,":[96,148,150],"developing":[100,268],"marginal":[101,151,154,176],"sinus":[102],"where":[103],"ED3+":[104],"macrophages":[105,173],"accumulate.":[106],"The":[107],"splenic":[108],"concentration":[109,184],"NE":[111,120,129,183,195],"(per":[112],"mg":[113],"wet":[114],"wt.)":[115],"3-methoxy-4-hydroxy-phenetheleneglycol":[117],"(MHPG),":[118],"a":[119,226,285],"metabolite,":[121],"increased":[122],"rapidly":[123],"during":[124,156],"this":[125,157],"period,":[126,158],"suggesting":[127],"that":[128,262],"is":[130],"available":[131],"released":[133],"these":[135],"nerves.":[136],"From":[137],"7-14":[138],"expanded":[143,211],"to":[144,172,212],"include":[145,213],"an":[146],"inner":[147,168],"sinus,":[152],"zone;":[155],"arborized":[161,238],"principally":[162],"PALS":[169,210],"adjacent":[171],"sinus.":[177],"14":[179],"days":[180,256],"age,":[182],"reached":[185],"adult":[186],"levels,":[187],"although":[188],"MHPG/NE":[190],"ratio":[191],"(an":[192],"index":[193],"turnover)":[196],"remained":[197],"higher":[198],"throughout":[199],"development":[200],"than":[201],"adulthood.":[203],"Finally,":[204],"14-28":[206],"follicles":[214],"containing":[215],"sIgM+":[216],"lymphocytes.":[218],"At":[219],"earliest":[221,275],"stages":[222,276],"follicular":[224],"development,":[225,279],"parafollicular":[227],"rim":[228],"was":[232],"present,":[233],"providing":[234,280],"occasional":[235],"branches":[236],"which":[237],"within":[239],"follicle.":[241],"No":[242],"further":[243],"changes":[244],"observed":[246],"either":[248],"or":[251],"cellular":[252],"after":[254],"28":[255],"age.":[258],"These":[259],"findings":[260],"suggest":[261],"are":[265],"compartments":[269],"their":[278],"interaction":[283],"variety":[286],"adrenoceptor-bearing":[288],"nonlymphoid":[291],"cells.":[292]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}