{"id":"https://openalex.org/W2006229155","doi":"https://doi.org/10.1002/ijc.2910210417","title":"Specificity of acquired clonal chromosome abnormalities in new zealand black mice","display_name":"Specificity of acquired clonal chromosome abnormalities in new zealand black mice","publication_year":1978,"publication_date":"1978-04-15","ids":{"openalex":"https://openalex.org/W2006229155","doi":"https://doi.org/10.1002/ijc.2910210417","mag":"2006229155","pmid":"https://pubmed.ncbi.nlm.nih.gov/669849"},"language":"en","primary_location":{"id":"doi:10.1002/ijc.2910210417","doi":"https://doi.org/10.1002/ijc.2910210417","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ijc.2910210417","pdf_url":null,"source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110018571","display_name":"Philip J. Fialkow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip J. Fialkow","raw_affiliation_strings":["Medical Genetics Section, Medical Service, Veterans Administration Hospital, Seattle, Wash. 98108"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Genetics Section, Medical Service, Veterans Administration Hospital, Seattle, Wash. 98108","institution_ids":["https://openalex.org/I1322918889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111793265","display_name":"Jean I. Bryant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean I. Bryant","raw_affiliation_strings":["Medical Genetics Section, Medical Service, Veterans Administration Hospital, Seattle, Wash. 98108"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Genetics Section, Medical Service, Veterans Administration Hospital, Seattle, Wash. 98108","institution_ids":["https://openalex.org/I1322918889"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051852805","display_name":"Jan M. Friedman","orcid":"https://orcid.org/0000-0002-7482-9570","observed_orcids":["https://orcid.org/0000-0002-7482-9570"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jan M. Friedman","raw_affiliation_strings":["Departments of Medicine and Genetics, University of Washington, Seattle, Wash., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Genetics, University of Washington, Seattle, Wash., USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5030,"currency":"USD","value_usd":5030},"apc_paid":null,"fwci":1.1368,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.7493465,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":"4","first_page":"505","last_page":"510"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.7035999894142151,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.7035999894142151,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.06939999759197235,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.05480000004172325,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/new-zealand-black-mice","display_name":"New Zealand Black mice","score":0.9679999947547913},{"id":"https://openalex.org/keywords/clonal-chromosomal-abnormalities","display_name":"clonal chromosomal abnormalities","score":0.7979999780654907},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.9819999933242798},{"id":"https://openalex.org/keywords/karyotypic-changes","display_name":"karyotypic changes","score":0.7080000042915344},{"id":"https://openalex.org/keywords/chromosome-15","display_name":"chromosome 15","score":0.9210000038146973},{"id":"https://openalex.org/keywords/lymphoreticular-malignancies","display_name":"lymphoreticular malignancies","score":0.8450000286102295},{"id":"https://openalex.org/keywords/immunodeficiency","display_name":"immunodeficiency","score":0.6520000100135803},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.7739999890327454},{"id":"https://openalex.org/keywords/splenocytes","display_name":"splenocytes","score":0.7950000166893005},{"id":"https://openalex.org/keywords/sex-chromosomes","display_name":"sex chromosomes","score":0.6660000085830688},{"id":"https://openalex.org/keywords/chromosome-2","display_name":"chromosome 2","score":0.6949999928474426},{"id":"https://openalex.org/keywords/chromosome-16","display_name":"chromosome 16","score":0.7979999780654907},{"id":"https://openalex.org/keywords/chromosome-17","display_name":"chromosome 17","score":0.9210000038146973}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7911677360534668},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.6521823406219482},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.5551274418830872},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5475864410400391},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5229412317276001},{"id":"https://openalex.org/C76725341","wikidata":"https://www.wikidata.org/wiki/Q1893126","display_name":"Inbred strain","level":3,"score":0.5127047300338745},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4822410047054291},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.4624612033367157},{"id":"https://openalex.org/C2780635560","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Neoplasm","level":2,"score":0.4412321150302887},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.42432066798210144},{"id":"https://openalex.org/C2777928079","wikidata":"https://www.wikidata.org/wiki/Q2677027","display_name":"Rat\u00f3n","level":2,"score":0.41192615032196045},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3853859603404999},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3275664150714874},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2614237666130066},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1622132956981659},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08299675583839417}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007621","descriptor_name":"Karyotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008814","descriptor_name":"Mice, Inbred NZB","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008814","descriptor_name":"Mice, Inbred NZB","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/ijc.2910210417","doi":"https://doi.org/10.1002/ijc.2910210417","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ijc.2910210417","pdf_url":null,"source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},{"id":"pmid:669849","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/669849","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of cancer","raw_type":"Journal Article"},{"id":"pmh:oai:mouseion.jax.org:ssbb1978-1748","doi":null,"is_oa":false,"landing_page_url":"https://mouseion.jax.org/ssbb1978/749","pdf_url":null,"source":{"id":"https://openalex.org/S4377196421","display_name":"The Mouseion at the JAXlibrary (Jackson Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115256","host_organization_name":"Jackson Laboratory","host_organization_lineage":["https://openalex.org/I4210115256"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Subject Strain Bibliography 1978","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46810001134872437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W169388299","https://openalex.org/W589640607","https://openalex.org/W1588051584","https://openalex.org/W1990837149","https://openalex.org/W2014968978","https://openalex.org/W2027768829","https://openalex.org/W2040727001","https://openalex.org/W2042145724","https://openalex.org/W2054932527","https://openalex.org/W2071713417","https://openalex.org/W2111486924","https://openalex.org/W2321570079","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2034099540","https://openalex.org/W6993103777","https://openalex.org/W2065036669","https://openalex.org/W7036664653","https://openalex.org/W1480621945","https://openalex.org/W7048204453","https://openalex.org/W1552484211","https://openalex.org/W2005237110","https://openalex.org/W1535803231","https://openalex.org/W1494585937"],"abstract_inverted_index":{"New":[0],"Zealand":[1],"Black":[2],"(NZB)":[3],"mice,":[4],"an":[5,73],"inbred":[6],"strain":[7],"characterized":[8],"by":[9],"immunological":[10],"dysfunction":[11],"and":[12,65,79,84],"lymphoreticular":[13,94],"malignancy,":[14],"also":[15],"develop":[16],"populations":[17],"of":[18,88],"aneuploid":[19],"spleen":[20],"cells.":[21],"In":[22],"detailed":[23],"cytogenetic":[24],"analyses":[25],"performed":[26],"on":[27],"10":[28],"NZBs,":[29],"the":[30,44,53,86],"chromosomally":[31],"abnormal":[32,93],"cells":[33],"were":[34,48],"found":[35],"to":[36],"be":[37],"clonally":[38],"related":[39],"within":[40],"each":[41],"mouse.":[42],"Moreover,":[43],"karyotypic":[45],"changes":[46],"observed":[47],"highly":[49],"non-random,":[50],"usually":[51],"involving":[52],"15":[54,90],"(10/10":[55],"mice),":[56,59,64],"2":[57],"(8/10":[58],"16":[60],"or":[61],"17":[62],"(9/10":[63],"sex":[66],"(6/10":[67],"mice)":[68],"chromosomes.":[69],"These":[70],"observations":[71],"suggest":[72],"important":[74],"relationship":[75],"between":[76],"chromosomal":[77],"alterations":[78],"tumorigenesis":[80],"in":[81,91],"NZB":[82],"mice":[83],"emphasize":[85],"role":[87],"chromosome":[89],"murine":[92],"proliferations.":[95]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}