{"id":"https://openalex.org/W2006201362","doi":"https://doi.org/10.1017/s0266462305050373","title":"Association between methodological characteristics and outcome in health technology assessments which included case series","display_name":"Association between methodological characteristics and outcome in health technology assessments which included case series","publication_year":2005,"publication_date":"2005-07-01","ids":{"openalex":"https://openalex.org/W2006201362","doi":"https://doi.org/10.1017/s0266462305050373","mag":"2006201362","pmid":"https://pubmed.ncbi.nlm.nih.gov/16110706"},"language":"en","primary_location":{"id":"doi:10.1017/s0266462305050373","doi":"https://doi.org/10.1017/s0266462305050373","is_oa":false,"landing_page_url":"https://doi.org/10.1017/s0266462305050373","pdf_url":null,"source":{"id":"https://openalex.org/S83891556","display_name":"International Journal of Technology Assessment in Health Care","issn_l":"0266-4623","issn":["0266-4623","1471-6348"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","fnege-4","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Technology Assessment in Health Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012494940","display_name":"Ken Stein","orcid":"https://orcid.org/0000-0002-5842-9972","observed_orcids":["https://orcid.org/0000-0002-5842-9972"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ken Stein","raw_affiliation_strings":["Peninsula Medical School, Exeter, Devon EX1 1PQ, UK. Ken.Stein@exeter.ac.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peninsula Medical School, Exeter, Devon EX1 1PQ, UK. Ken.Stein@exeter.ac.uk","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078953009","display_name":"Kim Dalziel","orcid":"https://orcid.org/0000-0003-4972-8871","observed_orcids":["https://orcid.org/0000-0003-4972-8871"]},"institutions":[{"id":"https://openalex.org/I85788879","display_name":"Peninsula College of Medicine and Dentistry","ror":"https://ror.org/04dtfyh05","country_code":"GB","type":"education","lineage":["https://openalex.org/I85788879"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kim Dalziel","raw_affiliation_strings":["Peninsula Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peninsula Medical School","institution_ids":["https://openalex.org/I85788879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024451410","display_name":"Ruth Garside","orcid":"https://orcid.org/0000-0003-1649-4773","observed_orcids":["https://orcid.org/0000-0003-1649-4773"]},"institutions":[{"id":"https://openalex.org/I85788879","display_name":"Peninsula College of Medicine and Dentistry","ror":"https://ror.org/04dtfyh05","country_code":"GB","type":"education","lineage":["https://openalex.org/I85788879"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ruth Garside","raw_affiliation_strings":["Peninsula Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peninsula Medical School","institution_ids":["https://openalex.org/I85788879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034609336","display_name":"E Castelnuovo","orcid":"https://orcid.org/0009-0001-3225-6751","observed_orcids":["https://orcid.org/0009-0001-3225-6751"]},"institutions":[{"id":"https://openalex.org/I85788879","display_name":"Peninsula College of Medicine and Dentistry","ror":"https://ror.org/04dtfyh05","country_code":"GB","type":"education","lineage":["https://openalex.org/I85788879"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emanuela Castelnuovo","raw_affiliation_strings":["Peninsula Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peninsula Medical School","institution_ids":["https://openalex.org/I85788879"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113563810","display_name":"Ali Round","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I85788879","display_name":"Peninsula College of Medicine and Dentistry","ror":"https://ror.org/04dtfyh05","country_code":"GB","type":"education","lineage":["https://openalex.org/I85788879"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ali Round","raw_affiliation_strings":["Peninsula Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peninsula Medical School","institution_ids":["https://openalex.org/I85788879"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.3828,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.71834153,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"21","issue":"3","first_page":"277","last_page":"287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12443","display_name":"Delphi Technique in Research","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12664","display_name":"Clinical practice guidelines implementation","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/case-series","display_name":"case series","score":0.9229999780654907},{"id":"https://openalex.org/keywords/health-technology-assessment","display_name":"health technology assessment","score":0.9150000214576721},{"id":"https://openalex.org/keywords/methodological-quality","display_name":"methodological quality","score":0.871999979019165},{"id":"https://openalex.org/keywords/quality-assessment-tools","display_name":"quality assessment tools","score":0.6980000138282776},{"id":"https://openalex.org/keywords/sample-size","display_name":"sample size","score":0.8100000023841858},{"id":"https://openalex.org/keywords/follow-up-duration","display_name":"follow-up duration","score":0.7680000066757202},{"id":"https://openalex.org/keywords/functional-endoscopic-sinus-surgery","display_name":"functional endoscopic sinus surgery","score":0.890999972820282},{"id":"https://openalex.org/keywords/nasal-polyps","display_name":"nasal polyps","score":0.8840000033378601},{"id":"https://openalex.org/keywords/spinal-cord-stimulation","display_name":"spinal cord stimulation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chronic-back-pain","display_name":"chronic back pain","score":0.9919999837875366},{"id":"https://openalex.org/keywords/percutaneous-transluminal-coronary-angioplasty","display_name":"percutaneous transluminal coronary angioplasty","score":0.9929999709129333},{"id":"https://openalex.org/keywords/coronary-artery-bypass-grafting","display_name":"coronary artery bypass grafting","score":0.9980000257492065},{"id":"https://openalex.org/keywords/stable-angina","display_name":"stable angina","score":0.7080000042915344},{"id":"https://openalex.org/keywords/systematic-reviews","display_name":"systematic reviews","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6277876496315002},{"id":"https://openalex.org/C199163554","wikidata":"https://www.wikidata.org/wiki/Q1681619","display_name":"Univariate","level":3,"score":0.6147168278694153},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.5392606854438782},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4914308786392212},{"id":"https://openalex.org/C148220186","wikidata":"https://www.wikidata.org/wiki/Q7111912","display_name":"Outcome (game theory)","level":2,"score":0.41658639907836914},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.3263072967529297},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09796497225761414},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013673","descriptor_name":"Technology Assessment, Biomedical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017063","descriptor_name":"Outcome Assessment, Health Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1017/s0266462305050373","doi":"https://doi.org/10.1017/s0266462305050373","is_oa":false,"landing_page_url":"https://doi.org/10.1017/s0266462305050373","pdf_url":null,"source":{"id":"https://openalex.org/S83891556","display_name":"International Journal of Technology Assessment in Health Care","issn_l":"0266-4623","issn":["0266-4623","1471-6348"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","fnege-4","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Technology Assessment in Health Care","raw_type":"journal-article"},{"id":"pmid:16110706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16110706","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of technology assessment in health care","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"No poverty","score":0.550000011920929,"id":"https://metadata.un.org/sdg/1"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1603966524","https://openalex.org/W1972698098","https://openalex.org/W1981531564","https://openalex.org/W1993553202","https://openalex.org/W2028479357","https://openalex.org/W2038426359","https://openalex.org/W2051778459","https://openalex.org/W2113264115","https://openalex.org/W2323923429","https://openalex.org/W2325625973","https://openalex.org/W2412963738","https://openalex.org/W4317564208"],"related_works":["https://openalex.org/W1997180991","https://openalex.org/W2396428004","https://openalex.org/W2000087081","https://openalex.org/W2093964794","https://openalex.org/W6983447105","https://openalex.org/W2102580392","https://openalex.org/W2332824910","https://openalex.org/W1483488155","https://openalex.org/W4406147454","https://openalex.org/W2375033352"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Case":[1],"series":[2,183,226,354],"constitute":[3],"a":[4,16,57,113,313],"weak":[5],"form":[6],"of":[7,11,18,38,47,59,66,135,138,143,168,170,191,206,262,265,280,282,292,312,328,342,350],"evidence":[8,205,275],"for":[9,15,34,71,77,91,260,289,325],"effectiveness":[10],"health":[12,26,60,360],"technologies.":[13],"However,":[14],"variety":[17],"reasons,":[19],"such":[20],"studies":[21,355],"may":[22],"be":[23],"included":[24,285],"in":[25,56,153,222,237,286,352],"technology":[27,61,361],"assessments.":[28,62],"There":[29],"are":[30],"no":[31,233,298],"clear":[32],"criteria":[33],"assessing":[35],"the":[36,48,120,198,278,283,306,339,348],"quality":[37,290,351],"case":[39,102,182,293,353],"series.":[40,103,294],"We":[41,272],"carried":[42],"out":[43],"an":[44,219],"empirical":[45],"investigation":[46],"association":[49,208],"between":[50,146,178,209,300,317],"outcome":[51,139,150,236,266,304,322,329],"frequency":[52],"and":[53,81,86,110,119,141,149,155,160,163,180,196,212,268,303,321],"methodological":[54,122,147,192,210,319],"characteristics":[55,211],"sample":[58,124],"METHODS:":[63],"Systematic":[64],"reviews":[65,176,224],"functional":[67],"endoscopic":[68],"sinus":[69],"surgery":[70],"nasal":[72],"polyps,":[73],"spinal":[74],"cord":[75],"stimulation":[76],"chronic":[78,92],"back":[79],"pain,":[80],"percutaneous":[82],"transluminal":[83],"coronary":[84,87],"angioplasty":[85],"artery":[88],"bypass":[89],"grafting":[90],"stable":[93],"angina":[94],"were":[95,105,151,250,258,323,334],"identified":[96],"as":[97,172,218],"containing":[98],"more":[99],"than":[100],"forty":[101],"Data":[104],"extracted":[106],"by":[107,112],"one":[108],"reviewer":[109],"checked":[111],"second":[114],"on":[115],"population":[116],"characteristics,":[117],"outcomes,":[118],"following":[121],"features:":[123],"size,":[125],"prospective/retrospective":[126],"approach,":[127],"consecutive":[128,254],"recruitment,":[129],"multi-":[130],"or":[131,166],"single-center":[132],"organization,":[133],"length":[134,261],"follow-up,":[136,263],"independence":[137,264],"measurement,":[140,267,330],"date":[142],"publication.":[144],"Association":[145],"features":[148,193],"explored":[152],"univariate":[154],"multivariate":[156],"analyses":[157],"using":[158],"parametric":[159],"nonparametric":[161],"tests":[162],"robust":[164],"regression":[165],"analysis":[167],"variance/analysis":[169],"covariance,":[171],"appropriate.":[173],"RESULTS:":[174],"Included":[175],"contained":[177],"forty-two":[179],"seventy-six":[181],"studies,":[184],"involving":[185],"5":[186],"to":[187,231,235,252,276,358],"172,283":[188],"participants.":[189],"Reporting":[190],"was":[194,228,243],"poor":[195],"limited":[197],"analyses.":[199,239],"In":[200],"general,":[201],"we":[202,296],"found":[203,273,297],"little":[204,274],"any":[207],"outcome.":[213,247],"Sample":[214],"size":[215,302],"is":[216,356],"used":[217,288],"inclusion":[220],"criterion":[221],"many":[223,281],"of'case":[225],"but":[227,331],"consistently":[229,337],"shown":[230,259,336],"have":[232],"relationship":[234,299,316],"all":[238],"A":[240],"prospective":[241],"approach":[242],"not":[244,335],"associated":[245],"with":[246],"Insufficient":[248],"data":[249],"available":[251],"explore":[253],"recruitment.":[255],"Mixed":[256],"results":[257],"publication":[269],"date.":[270],"CONCLUSIONS:":[271],"support":[277,359],"use":[279],"factors":[284,320],"tools":[287],"assessment":[291],"Importantly,":[295],"study":[301],"across":[305,338],"four":[307],"examples":[308,311,333,343],"studied.":[309,344],"Isolated":[310],"potentially":[314],"important":[315],"other":[318],"shown,":[324],"example,":[326],"blinding":[327],"these":[332],"small":[340],"number":[341],"Further":[345],"research":[346],"into":[347],"determinants":[349],"required":[357],"assessment.":[362]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}