{"id":"https://openalex.org/W2005993715","doi":"https://doi.org/10.1083/jcb.97.2.329","title":"Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes.","display_name":"Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes.","publication_year":1983,"publication_date":"1983-08-01","ids":{"openalex":"https://openalex.org/W2005993715","doi":"https://doi.org/10.1083/jcb.97.2.329","mag":"2005993715","pmid":"https://pubmed.ncbi.nlm.nih.gov/6309857"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.97.2.329","doi":"https://doi.org/10.1083/jcb.97.2.329","is_oa":true,"landing_page_url":"https://doi.org/10.1083/jcb.97.2.329","pdf_url":"https://rupress.org/jcb/article-pdf/97/2/329/1076976/329.pdf","source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rupress.org/jcb/article-pdf/97/2/329/1076976/329.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112821197","display_name":"Clifford V. Harding","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C Harding","raw_affiliation_strings":["Department of Physiology and Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110","Department of Physiology and Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Physiology and Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103202422","display_name":"John E. Heuser","orcid":"https://orcid.org/0000-0002-3593-8846","observed_orcids":["https://orcid.org/0000-0002-3593-8846"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Heuser","raw_affiliation_strings":["Department of Physiology and Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110","Department of Physiology and Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Physiology and Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064162089","display_name":"Philip D. Stahl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P Stahl","raw_affiliation_strings":["Department of Physiology and Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110","Department of Physiology and Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Physiology and Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":14.1436,"has_fulltext":true,"cited_by_count":1771,"citation_normalized_percentile":{"value":0.99525797,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"97","issue":"2","first_page":"329","last_page":"339"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transferrin","display_name":"transferrin","score":0.8090000152587891},{"id":"https://openalex.org/keywords/transferrin-receptor","display_name":"transferrin receptor","score":1.0},{"id":"https://openalex.org/keywords/receptor-mediated-endocytosis","display_name":"receptor-mediated endocytosis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/receptor-recycling","display_name":"receptor recycling","score":0.796999990940094},{"id":"https://openalex.org/keywords/reticulocytes","display_name":"reticulocytes","score":0.9929999709129333},{"id":"https://openalex.org/keywords/multivesicular-endosomes","display_name":"multivesicular endosomes","score":0.8769999742507935},{"id":"https://openalex.org/keywords/coated-pits","display_name":"coated pits","score":0.7630000114440918},{"id":"https://openalex.org/keywords/clathrin","display_name":"clathrin","score":0.8679999709129333},{"id":"https://openalex.org/keywords/colloidal-gold-labeling","display_name":"colloidal gold labeling","score":0.6439999938011169},{"id":"https://openalex.org/keywords/exocytosis","display_name":"exocytosis","score":0.7110000252723694},{"id":"https://openalex.org/keywords/spectrin","display_name":"spectrin","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.8950570225715637},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.8376025557518005},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.7219519019126892},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6651248931884766},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.6456116437911987},{"id":"https://openalex.org/C32264632","wikidata":"https://www.wikidata.org/wiki/Q1134983","display_name":"Transferrin receptor","level":3,"score":0.6418609619140625},{"id":"https://openalex.org/C117943116","wikidata":"https://www.wikidata.org/wiki/Q1135604","display_name":"Receptor-mediated endocytosis","level":4,"score":0.5313841700553894},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5060085654258728},{"id":"https://openalex.org/C2778403015","wikidata":"https://www.wikidata.org/wiki/Q1404923","display_name":"Reticulocyte","level":4,"score":0.4868547320365906},{"id":"https://openalex.org/C175969161","wikidata":"https://www.wikidata.org/wiki/Q323426","display_name":"Exocytosis","level":3,"score":0.4797985851764679},{"id":"https://openalex.org/C11569505","wikidata":"https://www.wikidata.org/wiki/Q727265","display_name":"Asialoglycoprotein receptor","level":4,"score":0.47558581829071045},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.460921049118042},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4399165213108063},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.4251784086227417},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40633392333984375},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4008602201938629},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.30537641048431396},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.14253279566764832},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.10118880867958069},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003034","descriptor_name":"Coated Pits, Cell-Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003034","descriptor_name":"Coated Pits, Cell-Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003034","descriptor_name":"Coated Pits, Cell-Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1083/jcb.97.2.329","doi":"https://doi.org/10.1083/jcb.97.2.329","is_oa":true,"landing_page_url":"https://doi.org/10.1083/jcb.97.2.329","pdf_url":"https://rupress.org/jcb/article-pdf/97/2/329/1076976/329.pdf","source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},{"id":"pmid:6309857","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6309857","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2112509","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2112509","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.280.3736","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.3736","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/9a/13/J_Cell_Biol_1983_Aug_1_97(2)_329-339.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1083/jcb.97.2.329","doi":"https://doi.org/10.1083/jcb.97.2.329","is_oa":true,"landing_page_url":"https://doi.org/10.1083/jcb.97.2.329","pdf_url":"https://rupress.org/jcb/article-pdf/97/2/329/1076976/329.pdf","source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005993715.pdf","grobid_xml":"https://content.openalex.org/works/W2005993715.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W101758766","https://openalex.org/W338255017","https://openalex.org/W980522815","https://openalex.org/W1498549327","https://openalex.org/W1505458972","https://openalex.org/W1603151752","https://openalex.org/W1854787066","https://openalex.org/W1965467384","https://openalex.org/W1968065552","https://openalex.org/W1969183608","https://openalex.org/W1970570888","https://openalex.org/W1970869190","https://openalex.org/W1977519858","https://openalex.org/W1978234566","https://openalex.org/W1980860909","https://openalex.org/W1983169741","https://openalex.org/W1993836591","https://openalex.org/W1995587987","https://openalex.org/W1996266650","https://openalex.org/W2002825574","https://openalex.org/W2005040298","https://openalex.org/W2030655780","https://openalex.org/W2040283218","https://openalex.org/W2050740526","https://openalex.org/W2064146346","https://openalex.org/W2066558638","https://openalex.org/W2066900699","https://openalex.org/W2068104571","https://openalex.org/W2068908098","https://openalex.org/W2078644893","https://openalex.org/W2080477433","https://openalex.org/W2087614483","https://openalex.org/W2088084755","https://openalex.org/W2093275133","https://openalex.org/W2110408216","https://openalex.org/W2132268688","https://openalex.org/W2139831220","https://openalex.org/W2149817638","https://openalex.org/W2291937974","https://openalex.org/W2394630666","https://openalex.org/W2410758188","https://openalex.org/W2944579281","https://openalex.org/W3187753197"],"related_works":["https://openalex.org/W2086905421","https://openalex.org/W2400692507","https://openalex.org/W1993836591","https://openalex.org/W2053061144","https://openalex.org/W2035770984","https://openalex.org/W2184263350","https://openalex.org/W2040003455","https://openalex.org/W2492991913","https://openalex.org/W1585969322","https://openalex.org/W1554036089"],"abstract_inverted_index":{"At":[0,97],"4":[1,31,57],"degrees":[2,16,26,32,45,58,69,99,129,187],"C":[3,17,27,33,59,100],"transferrin":[4,21,48,88,222,233],"bound":[5,47],"to":[6,161,240],"receptors":[7,72],"on":[8],"the":[9,94,147,194,202,208,211,215,241],"reticulocyte":[10],"plasma":[11,148,216,242],"membrane,":[12],"and":[13,36,79,108,118,150,166,190,200,228,230,234],"at":[14,24,30,43,56,67,82,127,185],"37":[15,25,44,68,98,128,186],"receptor-mediated":[18],"endocytosis":[19],"of":[20,157,168,196,204,214],"occurred.":[22],"Uptake":[23],"exceeded":[28],"binding":[29],"by":[34,154],"2.5-fold":[35],"saturated":[37],"after":[38,122,137,244],"20-30":[39],"min.":[40],"During":[41],"uptake":[42,80],"C,":[46,70],"was":[49,89,171,180],"internalized":[50,224],"into":[51,93],"a":[52,83],"trypsin-resistant":[53],"space.":[54,96],"Trypsinization":[55],"destroyed":[60],"surface":[61,71,213],"receptors,":[62],"but":[63],"with":[64,146,182],"subsequent":[65,183],"incubation":[66,184],"rapidly":[73],"appeared":[74,110,160],"(albeit":[75],"in":[76,105,164,173,198],"reduced":[77],"numbers),":[78],"occurred":[81],"decreased":[84],"level.":[85],"After":[86],"endocytosis,":[87],"released,":[90],"apparently":[91,144],"intact,":[92],"extracellular":[95],"colloidal":[101],"gold-transferrin":[102],"(AuTf)":[103],"clustered":[104],"coated":[106,226],"pits":[107,227],"then":[109],"inside":[111],"various":[112],"intracellular":[113,169],"membrane-bounded":[114],"compartments.":[115,176],"Small":[116],"vesicles":[117,229],"tubules":[119],"were":[120],"labeled":[121,136],"short":[123],"(5-10":[124],"min)":[125,140],"incubations":[126],"C.":[130,188],"Larger":[131],"multivesicular":[132],"endosomes":[133,143],"became":[134],"heavily":[135],"longer":[138],"(20-35":[139],"incubations.":[141],"Multivesicular":[142],"fused":[145],"membrane":[149,243],"released":[151,181],"their":[152],"contents":[153],"exocytosis.":[155],"None":[156],"these":[158],"organelles":[159],"be":[162],"lysosomal":[163],"nature,":[165],"98%":[167],"AuTf":[170,197],"localized":[172],"acid":[174],"phosphatase-negative":[175],"AuTf,":[177],"like":[178],"transferrin,":[179],"Freeze-dried":[189],"freeze-fractured":[191],"reticulocytes":[192,199],"confirmed":[193],"distribution":[195],"revealed":[201],"presence":[203],"clathrin-coated":[205],"patches":[206],"amidst":[207],"spectrin":[209],"coating":[210],"inner":[212],"membrane.":[217],"These":[218],"data":[219],"suggest":[220],"that":[221,232],"is":[223],"via":[225],"demonstrate":[231],"its":[235],"receptor":[236],"are":[237],"recycled":[238],"back":[239],"endocytosis.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":74},{"year":2025,"cited_by_count":105},{"year":2024,"cited_by_count":119},{"year":2023,"cited_by_count":136},{"year":2022,"cited_by_count":150},{"year":2021,"cited_by_count":151},{"year":2020,"cited_by_count":155},{"year":2019,"cited_by_count":127},{"year":2018,"cited_by_count":92},{"year":2017,"cited_by_count":80},{"year":2016,"cited_by_count":80},{"year":2015,"cited_by_count":63},{"year":2014,"cited_by_count":48},{"year":2013,"cited_by_count":31},{"year":2012,"cited_by_count":35}],"updated_date":"2026-10-18T09:31:52.927876","created_date":"2025-10-10T00:00:00"}