{"id":"https://openalex.org/W2005947649","doi":"https://doi.org/10.1016/0360-3016(78)90110-4","title":"The bone marrow organ: The critical structure in radiation-drug interaction","display_name":"The bone marrow organ: The critical structure in radiation-drug interaction","publication_year":1978,"publication_date":"1978-01-01","ids":{"openalex":"https://openalex.org/W2005947649","doi":"https://doi.org/10.1016/0360-3016(78)90110-4","mag":"2005947649","pmid":"https://pubmed.ncbi.nlm.nih.gov/344290"},"language":"en","primary_location":{"id":"doi:10.1016/0360-3016(78)90110-4","doi":"https://doi.org/10.1016/0360-3016(78)90110-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0360-3016(78)90110-4","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109197283","display_name":"Philip Rubin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip Rubin","raw_affiliation_strings":["Division of Radiation Oncology, University of Rochester Cancer Center and Radiation Research Center, 601 Elmwood Avenue, Rochester, NY 14642, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiation Oncology, University of Rochester Cancer Center and Radiation Research Center, 601 Elmwood Avenue, Rochester, NY 14642, U.S.A","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010410691","display_name":"Charles W. Scarantino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles W Scarantino","raw_affiliation_strings":["Division of Radiation Oncology, University of Rochester Cancer Center and Radiation Research Center, 601 Elmwood Avenue, Rochester, NY 14642, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiation Oncology, University of Rochester Cancer Center and Radiation Research Center, 601 Elmwood Avenue, Rochester, NY 14642, U.S.A","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":0.8989,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.59090909,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"4","issue":"1-2","first_page":"3","last_page":"23"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13123","display_name":"Advances in Oncology and Radiotherapy","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-marrow","display_name":"bone marrow","score":0.9589999914169312},{"id":"https://openalex.org/keywords/radiation-chemotherapy-interaction","display_name":"radiation-chemotherapy interaction","score":0.8199999928474426},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.8550000190734863},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.48100000619888306},{"id":"https://openalex.org/keywords/hematopoietic-toxicity","display_name":"hematopoietic toxicity","score":0.7229999899864197},{"id":"https://openalex.org/keywords/multidisciplinary-oncology","display_name":"multidisciplinary oncology","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7238447070121765},{"id":"https://openalex.org/C2781354396","wikidata":"https://www.wikidata.org/wiki/Q840407","display_name":"Enthusiasm","level":2,"score":0.6185466647148132},{"id":"https://openalex.org/C2777113389","wikidata":"https://www.wikidata.org/wiki/Q208195","display_name":"Pleasure","level":2,"score":0.5292344093322754},{"id":"https://openalex.org/C2780138299","wikidata":"https://www.wikidata.org/wiki/Q3404265","display_name":"Privilege (computing)","level":2,"score":0.5219739675521851},{"id":"https://openalex.org/C2779438500","wikidata":"https://www.wikidata.org/wiki/Q27070331","display_name":"Honor","level":2,"score":0.49698808789253235},{"id":"https://openalex.org/C33566652","wikidata":"https://www.wikidata.org/wiki/Q1065927","display_name":"Theme (computing)","level":2,"score":0.4677702784538269},{"id":"https://openalex.org/C136197465","wikidata":"https://www.wikidata.org/wiki/Q1729295","display_name":"Variety (cybernetics)","level":2,"score":0.4187600612640381},{"id":"https://openalex.org/C11171543","wikidata":"https://www.wikidata.org/wiki/Q41630","display_name":"Psychoanalysis","level":1,"score":0.3827631175518036},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.26896095275878906},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1895538866519928},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1292799711227417},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.1242072582244873},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.1078992486000061},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.10123750567436218},{"id":"https://openalex.org/C108827166","wikidata":"https://www.wikidata.org/wiki/Q175975","display_name":"Internet privacy","level":1,"score":0.09827882051467896},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014965","descriptor_name":"X-Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0360-3016(78)90110-4","doi":"https://doi.org/10.1016/0360-3016(78)90110-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0360-3016(78)90110-4","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},{"id":"pmid:344290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/344290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of radiation oncology, biology, physics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":110,"referenced_works":["https://openalex.org/W5387557","https://openalex.org/W83821849","https://openalex.org/W97874614","https://openalex.org/W102126571","https://openalex.org/W193514409","https://openalex.org/W207504333","https://openalex.org/W304083697","https://openalex.org/W306249600","https://openalex.org/W563615900","https://openalex.org/W589593597","https://openalex.org/W1454412255","https://openalex.org/W1502195644","https://openalex.org/W1539758070","https://openalex.org/W1543601580","https://openalex.org/W1561219198","https://openalex.org/W1597503840","https://openalex.org/W1603285908","https://openalex.org/W1608480048","https://openalex.org/W1751777755","https://openalex.org/W1954687338","https://openalex.org/W1968541478","https://openalex.org/W1970027015","https://openalex.org/W1974643187","https://openalex.org/W1974699858","https://openalex.org/W1981452363","https://openalex.org/W1985511199","https://openalex.org/W1990925489","https://openalex.org/W1992509095","https://openalex.org/W1992875645","https://openalex.org/W1994005628","https://openalex.org/W2000765609","https://openalex.org/W2000969529","https://openalex.org/W2002115980","https://openalex.org/W2002287505","https://openalex.org/W2002493103","https://openalex.org/W2005285327","https://openalex.org/W2006618705","https://openalex.org/W2008192185","https://openalex.org/W2008424319","https://openalex.org/W2008664052","https://openalex.org/W2010109106","https://openalex.org/W2015495528","https://openalex.org/W2015832459","https://openalex.org/W2017257255","https://openalex.org/W2017735814","https://openalex.org/W2019309819","https://openalex.org/W2021392990","https://openalex.org/W2024015806","https://openalex.org/W2026941508","https://openalex.org/W2030203472","https://openalex.org/W2031071974","https://openalex.org/W2036492806","https://openalex.org/W2042132060","https://openalex.org/W2042730130","https://openalex.org/W2048104971","https://openalex.org/W2048829754","https://openalex.org/W2052428535","https://openalex.org/W2053677719","https://openalex.org/W2055505824","https://openalex.org/W2057091558","https://openalex.org/W2058292222","https://openalex.org/W2060694900","https://openalex.org/W2063364335","https://openalex.org/W2064723517","https://openalex.org/W2065489653","https://openalex.org/W2066464496","https://openalex.org/W2066482506","https://openalex.org/W2067143275","https://openalex.org/W2074934556","https://openalex.org/W2076062933","https://openalex.org/W2077825867","https://openalex.org/W2078136555","https://openalex.org/W2078761532","https://openalex.org/W2079875880","https://openalex.org/W2080082952","https://openalex.org/W2092428502","https://openalex.org/W2093042287","https://openalex.org/W2103546044","https://openalex.org/W2107988590","https://openalex.org/W2113734868","https://openalex.org/W2119086402","https://openalex.org/W2123159008","https://openalex.org/W2132085924","https://openalex.org/W2141794586","https://openalex.org/W2154037033","https://openalex.org/W2156628744","https://openalex.org/W2172249895","https://openalex.org/W2257048366","https://openalex.org/W2266781400","https://openalex.org/W2271383465","https://openalex.org/W2276841365","https://openalex.org/W2288226379","https://openalex.org/W2297833295","https://openalex.org/W2330432432","https://openalex.org/W2335332412","https://openalex.org/W2335660413","https://openalex.org/W2336595264","https://openalex.org/W2343364099","https://openalex.org/W2374399131","https://openalex.org/W2406712596","https://openalex.org/W2409633474","https://openalex.org/W2413333057","https://openalex.org/W2414538489","https://openalex.org/W2414878012","https://openalex.org/W2415549723","https://openalex.org/W2424830585","https://openalex.org/W2561898719","https://openalex.org/W4252030004","https://openalex.org/W4253710143","https://openalex.org/W4299857695"],"related_works":["https://openalex.org/W4231374878","https://openalex.org/W7017424315","https://openalex.org/W4230330670","https://openalex.org/W1997118172","https://openalex.org/W145545622","https://openalex.org/W2041783096","https://openalex.org/W4253890344","https://openalex.org/W2096122852","https://openalex.org/W1995773980","https://openalex.org/W3152568186"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
