{"id":"https://openalex.org/W2005806113","doi":"https://doi.org/10.1126/science.1251033","title":"Transcriptional diversity during lineage commitment of human blood progenitors","display_name":"Transcriptional diversity during lineage commitment of human blood progenitors","publication_year":2014,"publication_date":"2014-09-25","ids":{"openalex":"https://openalex.org/W2005806113","doi":"https://doi.org/10.1126/science.1251033","mag":"2005806113","pmid":"https://pubmed.ncbi.nlm.nih.gov/25258084"},"language":"en","primary_location":{"id":"doi:10.1126/science.1251033","doi":"https://doi.org/10.1126/science.1251033","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.1251033","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4254742/pdf/emss-60870.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100432094","display_name":"Lu Chen","orcid":"https://orcid.org/0000-0002-5701-9306","observed_orcids":["https://orcid.org/0000-0002-5701-9306","https://orcid.org/0009-0005-1808-7137"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Lu Chen","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]},{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029443733","display_name":"Myrto A. Kostadima","orcid":"https://orcid.org/0000-0002-1818-4050","observed_orcids":["https://orcid.org/0000-0002-1818-4050"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Myrto Kostadima","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014988213","display_name":"Joost H.A. Martens","orcid":"https://orcid.org/0000-0003-2008-6537","observed_orcids":["https://orcid.org/0000-0003-2008-6537"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Joost H. A. Martens","raw_affiliation_strings":["Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006012243","display_name":"Giovanni Canu","orcid":"https://orcid.org/0000-0002-3349-4479","observed_orcids":["https://orcid.org/0000-0002-3349-4479"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Giovanni Canu","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090382635","display_name":"Sara P. Garcia","orcid":"https://orcid.org/0000-0003-3312-6454","observed_orcids":["https://orcid.org/0000-0003-3312-6454"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sara P. Garcia","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010947173","display_name":"Ernest Turro","orcid":"https://orcid.org/0000-0002-1820-6563","observed_orcids":["https://orcid.org/0000-0002-1820-6563"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ernest Turro","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080352902","display_name":"Kate Downes","orcid":"https://orcid.org/0000-0003-0366-1579","observed_orcids":["https://orcid.org/0000-0003-0366-1579"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kate Downes","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038220581","display_name":"Iain C. Macaulay","orcid":"https://orcid.org/0000-0002-6761-757X","observed_orcids":["https://orcid.org/0000-0002-6761-757X"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Iain C. Macaulay","raw_affiliation_strings":["Sanger Institute\u2013EBI Single-Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanger Institute\u2013EBI Single-Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077354024","display_name":"Ewa Bielczyk-Maczy\u0144ska","orcid":"https://orcid.org/0000-0002-0558-1188","observed_orcids":["https://orcid.org/0000-0002-0558-1188"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ewa Bielczyk-Maczynska","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108261182","display_name":"S. Coe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sophia Coe","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089709333","display_name":"Samantha Farrow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Samantha Farrow","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030664517","display_name":"Pawan Poudel","orcid":"https://orcid.org/0000-0002-9704-4987","observed_orcids":["https://orcid.org/0000-0002-9704-4987"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pawan Poudel","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106916745","display_name":"Frances Burden","orcid":"https://orcid.org/0000-0001-6266-1304","observed_orcids":["https://orcid.org/0000-0001-6266-1304"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Frances Burden","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060298240","display_name":"Sjoert B.G. Jansen","orcid":"https://orcid.org/0000-0002-3728-644X","observed_orcids":["https://orcid.org/0000-0002-3728-644X"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sjoert B. G. Jansen","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003779182","display_name":"William John Astle","orcid":"https://orcid.org/0000-0001-8866-6672","observed_orcids":["https://orcid.org/0000-0001-8866-6672"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"William J. Astle","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Medical Research Council Biostatistics Unit, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Medical Research Council Biostatistics Unit, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK","institution_ids":["https://openalex.org/I4210134973","https://openalex.org/I90344618"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037518409","display_name":"Antony Attwood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Antony Attwood","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013068112","display_name":"Tadbir K. Bariana","orcid":"https://orcid.org/0000-0003-4045-3330","observed_orcids":["https://orcid.org/0000-0003-4045-3330"]},"institutions":[{"id":"https://openalex.org/I169248724","display_name":"Royal Free London NHS Foundation Trust","ror":"https://ror.org/04rtdp853","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724"]},{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tadbir Bariana","raw_affiliation_strings":["Department of Haematology, University College London Cancer Institute, London WC1E 6DD, UK","The Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free NHS Trust, London NW3 2QG, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University College London Cancer Institute, London WC1E 6DD, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"The Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free NHS Trust, London NW3 2QG, UK","institution_ids":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054690280","display_name":"Bernard de Bono","orcid":"https://orcid.org/0000-0003-0638-5274","observed_orcids":["https://orcid.org/0000-0003-0638-5274"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB","NZ"],"is_corresponding":false,"raw_author_name":"Bernard de Bono","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, Auckland 1010, New Zealand","CHIME Institute, University College London, Archway Campus, London NW1 2DA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, Auckland 1010, New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"CHIME Institute, University College London, Archway Campus, London NW1 2DA, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079945791","display_name":"Alessandra Breschi","orcid":"https://orcid.org/0000-0001-6464-6693","observed_orcids":["https://orcid.org/0000-0001-6464-6693"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210137962","display_name":"Centre for Genomic Regulation","ror":"https://ror.org/03wyzt892","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210132884","https://openalex.org/I4210137962","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alessandra Breschi","raw_affiliation_strings":["Centre for Genomic Regulation and University Pompeu Fabra, 08002 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Genomic Regulation and University Pompeu Fabra, 08002 Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210137962"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022055808","display_name":"John Campbell Chambers","orcid":"https://orcid.org/0000-0003-0209-4541","observed_orcids":["https://orcid.org/0000-0003-0209-4541","https://orcid.org/0000-0002-7169-3786"]},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I4210163491","display_name":"Ealing Hospital NHS Trust","ror":"https://ror.org/0380w8h49","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210163491"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John C. Chambers","raw_affiliation_strings":["Ealing Hospital NHS Trust, Southall, Middlesex UB1 3HW, UK","Imperial College Healthcare NHS Trust, DuCane Road, London W12 0HS, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ealing Hospital NHS Trust, Southall, Middlesex UB1 3HW, UK","institution_ids":["https://openalex.org/I4210163491"]},{"raw_affiliation_string":"Imperial College Healthcare NHS Trust, DuCane Road, London W12 0HS, UK","institution_ids":["https://openalex.org/I153355300"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066162733","display_name":"Fizzah Choudry","orcid":"https://orcid.org/0000-0002-9475-5257","observed_orcids":["https://orcid.org/0000-0002-9475-5257"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Fizzah A. Choudry","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082531083","display_name":"Laura Clarke","orcid":"https://orcid.org/0000-0002-5989-6898","observed_orcids":["https://orcid.org/0000-0002-5989-6898"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Laura Clarke","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064250713","display_name":"Paul G. Coupland","orcid":"https://orcid.org/0000-0002-2871-3374","observed_orcids":["https://orcid.org/0000-0002-2871-3374"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Coupland","raw_affiliation_strings":["Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048810504","display_name":"Martijn van der Ent","orcid":"https://orcid.org/0009-0004-4041-6403","observed_orcids":["https://orcid.org/0009-0004-4041-6403"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Martijn van der Ent","raw_affiliation_strings":["Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017746448","display_name":"Wendy N. Erber","orcid":"https://orcid.org/0000-0002-1028-9376","observed_orcids":["https://orcid.org/0000-0002-1028-9376"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Wendy N. Erber","raw_affiliation_strings":["Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia 6009, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia 6009, Australia","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020940867","display_name":"Joop H. Jansen","orcid":"https://orcid.org/0000-0001-9459-568X","observed_orcids":["https://orcid.org/0000-0001-9459-568X"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Joop H. Jansen","raw_affiliation_strings":["Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006481887","display_name":"R\u00e9mi Favier","orcid":"https://orcid.org/0000-0003-1850-6686","observed_orcids":["https://orcid.org/0000-0003-1850-6686"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"R\u00e9mi Favier","raw_affiliation_strings":["Assistance Publique\u2013Hopitaux de Paris, INSERM U1009, 94805 Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistance Publique\u2013Hopitaux de Paris, INSERM U1009, 94805 Villejuif, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085035732","display_name":"Matthew E. Fenech","orcid":"https://orcid.org/0000-0001-9970-0215","observed_orcids":["https://orcid.org/0000-0001-9970-0215"]},"institutions":[{"id":"https://openalex.org/I1118541","display_name":"University of East Anglia","ror":"https://ror.org/026k5mg93","country_code":"GB","type":"education","lineage":["https://openalex.org/I1118541"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew E. Fenech","raw_affiliation_strings":["Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK","institution_ids":["https://openalex.org/I1118541"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110231437","display_name":"Nicola S. Foad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicola Foad","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064832605","display_name":"Kathleen Freson","orcid":"https://orcid.org/0000-0002-4381-2442","observed_orcids":["https://orcid.org/0000-0002-4381-2442"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Kathleen Freson","raw_affiliation_strings":["Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059991336","display_name":"Chris Van Geet","orcid":"https://orcid.org/0000-0003-1342-6265","observed_orcids":["https://orcid.org/0000-0003-1342-6265"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Chris van Geet","raw_affiliation_strings":["Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033248039","display_name":"Keith Gomez","orcid":"https://orcid.org/0000-0002-8934-0700","observed_orcids":["https://orcid.org/0000-0002-8934-0700"]},"institutions":[{"id":"https://openalex.org/I169248724","display_name":"Royal Free London NHS Foundation Trust","ror":"https://ror.org/04rtdp853","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724"]},{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Keith Gomez","raw_affiliation_strings":["The Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free NHS Trust, London NW3 2QG, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free NHS Trust, London NW3 2QG, UK","institution_ids":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067701434","display_name":"Roderic Guig\u00f3","orcid":"https://orcid.org/0000-0002-5738-4477","observed_orcids":["https://orcid.org/0000-0002-5738-4477"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210137962","display_name":"Centre for Genomic Regulation","ror":"https://ror.org/03wyzt892","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210132884","https://openalex.org/I4210137962","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Roderic Guigo","raw_affiliation_strings":["Centre for Genomic Regulation and University Pompeu Fabra, 08002 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Genomic Regulation and University Pompeu Fabra, 08002 Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210137962"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Daniel Hampshire","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Daniel Hampshire","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072588445","display_name":"Anne M. Kelly","orcid":"https://orcid.org/0000-0003-2945-4463","observed_orcids":["https://orcid.org/0000-0003-2945-4463"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2802466933","display_name":"Cambridge University Hospitals NHS Foundation Trust","ror":"https://ror.org/04v54gj93","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anne M. Kelly","raw_affiliation_strings":["Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge B2 0QQ, UK","Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge B2 0QQ, UK","institution_ids":["https://openalex.org/I2802466933"]},{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021037399","display_name":"Hindrik H. D. Kerstens","orcid":"https://orcid.org/0000-0003-2289-4108","observed_orcids":["https://orcid.org/0000-0003-2289-4108"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hindrik H. D. Kerstens","raw_affiliation_strings":["Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044788808","display_name":"Jaspal Singh Kooner","orcid":"https://orcid.org/0000-0003-2086-4837","observed_orcids":["https://orcid.org/0000-0003-2086-4837"]},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I4210163491","display_name":"Ealing Hospital NHS Trust","ror":"https://ror.org/0380w8h49","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210163491"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jaspal S. Kooner","raw_affiliation_strings":["Ealing Hospital NHS Trust, Southall, Middlesex UB1 3HW, UK","Imperial College Healthcare NHS Trust, DuCane Road, London W12 0HS, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ealing Hospital NHS Trust, Southall, Middlesex UB1 3HW, UK","institution_ids":["https://openalex.org/I4210163491"]},{"raw_affiliation_string":"Imperial College Healthcare NHS Trust, DuCane Road, London W12 0HS, UK","institution_ids":["https://openalex.org/I153355300"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039321983","display_name":"Michael Laffan","orcid":"https://orcid.org/0000-0002-8268-3268","observed_orcids":["https://orcid.org/0000-0002-8268-3268"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Laffan","raw_affiliation_strings":["Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London W12 0HS, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London W12 0HS, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059772281","display_name":"Claire Lentaigne","orcid":"https://orcid.org/0000-0003-0406-4776","observed_orcids":["https://orcid.org/0000-0003-0406-4776"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Claire Lentaigne","raw_affiliation_strings":["Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London W12 0HS, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London W12 0HS, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070482265","display_name":"Charlotte Labalette","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Charlotte Labalette","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032712642","display_name":"Tiphaine C. Martin","orcid":"https://orcid.org/0000-0001-9990-1455","observed_orcids":["https://orcid.org/0000-0001-9990-1455"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I1324925910","display_name":"St Thomas' Hospital","ror":"https://ror.org/054gk2851","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324925910","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tiphaine Martin","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Department of Twin Research &amp; Genetic Epidemiology, Genetics and Molecular Medicine Division, St Thomas\u2019 Hospital, King\u2019s College, London SE1 7EH, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Twin Research &amp; Genetic Epidemiology, Genetics and Molecular Medicine Division, St Thomas\u2019 Hospital, King\u2019s College, London SE1 7EH, UK","institution_ids":["https://openalex.org/I1324925910","https://openalex.org/I183935753"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016355049","display_name":"Stuart Meacham","orcid":"https://orcid.org/0000-0002-3667-6059","observed_orcids":["https://orcid.org/0000-0002-3667-6059"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stuart Meacham","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025294145","display_name":"Andrew David Mumford","orcid":"https://orcid.org/0000-0002-5523-511X","observed_orcids":["https://orcid.org/0000-0002-5523-511X"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Mumford","raw_affiliation_strings":["School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005918243","display_name":"Sylvia N\u00fcrnberg","orcid":"https://orcid.org/0000-0002-0869-484X","observed_orcids":["https://orcid.org/0000-0002-0869-484X"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sylvia T. N\u00fcrnberg","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003109164","display_name":"Emilio Palumbo","orcid":"https://orcid.org/0000-0003-4599-8161","observed_orcids":["https://orcid.org/0000-0003-4599-8161"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210137962","display_name":"Centre for Genomic Regulation","ror":"https://ror.org/03wyzt892","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210132884","https://openalex.org/I4210137962","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Emilio Palumbo","raw_affiliation_strings":["Centre for Genomic Regulation and University Pompeu Fabra, 08002 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Genomic Regulation and University Pompeu Fabra, 08002 Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210137962"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050125183","display_name":"Bert A. van der Reijden","orcid":"https://orcid.org/0000-0001-7804-8643","observed_orcids":["https://orcid.org/0000-0001-7804-8643"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bert A. van der Reijden","raw_affiliation_strings":["Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031861795","display_name":"David Richardson","orcid":"https://orcid.org/0000-0003-0247-9118","observed_orcids":["https://orcid.org/0000-0003-0247-9118"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Richardson","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033841355","display_name":"Stephen\u2010John Sammut","orcid":"https://orcid.org/0000-0003-4472-904X","observed_orcids":["https://orcid.org/0000-0003-4472-904X"]},"institutions":[{"id":"https://openalex.org/I2801316944","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801316944"]},{"id":"https://openalex.org/I4210156194","display_name":"Addenbrooke's Hospital","ror":"https://ror.org/055vbxf86","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933","https://openalex.org/I4210156194"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen J. Sammut","raw_affiliation_strings":["Cancer Research UK, Cambridge Institute, Cambridge Biomedical Campus, Cambridge CB2 0RE, UK","Department of Oncology, Addenbrooke\u2019s Cambridge University Hospital NHS Trust, Cambridge Biomedical Campus, Cambridge CB2 0RE, UK","Department of Oncology, Addenbrooke's Cambridge University Hospital NHS Trust, Cambridge Biomedical Campus, Cambridge CB2 0RE, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Research UK, Cambridge Institute, Cambridge Biomedical Campus, Cambridge CB2 0RE, UK","institution_ids":["https://openalex.org/I2801316944"]},{"raw_affiliation_string":"Department of Oncology, Addenbrooke\u2019s Cambridge University Hospital NHS Trust, Cambridge Biomedical Campus, Cambridge CB2 0RE, UK","institution_ids":["https://openalex.org/I4210156194"]},{"raw_affiliation_string":"Department of Oncology, Addenbrooke's Cambridge University Hospital NHS Trust, Cambridge Biomedical Campus, Cambridge CB2 0RE, UK","institution_ids":["https://openalex.org/I4210156194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087664677","display_name":"Greg Slodkowicz","orcid":"https://orcid.org/0000-0001-6918-0386","observed_orcids":["https://orcid.org/0000-0001-6918-0386"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Greg Slodkowicz","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086246480","display_name":"Asif U. Tamuri","orcid":"https://orcid.org/0000-0001-6633-3789","observed_orcids":["https://orcid.org/0000-0001-6633-3789"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Asif U. Tamuri","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048164104","display_name":"Louella J. Vasquez","orcid":"https://orcid.org/0000-0002-5758-6036","observed_orcids":["https://orcid.org/0000-0002-5758-6036"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Louella Vasquez","raw_affiliation_strings":["National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064045478","display_name":"Katrin Vo\u00df","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Katrin Voss","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110589774","display_name":"Stephen B. Watt","orcid":"https://orcid.org/0000-0001-8303-4983","observed_orcids":["https://orcid.org/0000-0001-8303-4983"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen Watt","raw_affiliation_strings":["National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061998269","display_name":"Sarah K. Westbury","orcid":"https://orcid.org/0000-0002-0950-8148","observed_orcids":["https://orcid.org/0000-0002-0950-8148"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sarah Westbury","raw_affiliation_strings":["School of Clinical Sciences, University of Bristol, Bristol BS2 8DZ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Clinical Sciences, University of Bristol, Bristol BS2 8DZ, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006816272","display_name":"Paul Flicek","orcid":"https://orcid.org/0000-0002-3897-7955","observed_orcids":["https://orcid.org/0000-0002-3897-7955"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Flicek","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]},{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107974625","display_name":"Remco Loos","orcid":"https://orcid.org/0000-0002-9850-6821","observed_orcids":["https://orcid.org/0000-0002-9850-6821"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Remco Loos","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020967139","display_name":"Nick Goldman","orcid":"https://orcid.org/0000-0001-8486-2211","observed_orcids":["https://orcid.org/0000-0001-8486-2211"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nick Goldman","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023094545","display_name":"Paul Bertone","orcid":"https://orcid.org/0000-0001-5059-4829","observed_orcids":["https://orcid.org/0000-0001-5059-4829"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Paul Bertone","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","Genome Biology and Developmental Biology Units, European Molecular Biology Laboratory, 69117 Heidelberg, Germany","Wellcome Trust\u2014Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge CB2 1QR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]},{"raw_affiliation_string":"Genome Biology and Developmental Biology Units, European Molecular Biology Laboratory, 69117 Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]},{"raw_affiliation_string":"Wellcome Trust\u2014Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge CB2 1QR, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068323278","display_name":"Randy J. Read","orcid":"https://orcid.org/0000-0001-8273-0047","observed_orcids":["https://orcid.org/0000-0001-8273-0047"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Randy J. Read","raw_affiliation_strings":["Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086827100","display_name":"Sylvia T. Richardson","orcid":"https://orcid.org/0000-0003-1998-492X","observed_orcids":["https://orcid.org/0000-0003-1998-492X"]},"institutions":[{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sylvia Richardson","raw_affiliation_strings":["Medical Research Council Biostatistics Unit, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Biostatistics Unit, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK","institution_ids":["https://openalex.org/I4210134973","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036718218","display_name":"Ana Cvejic","orcid":"https://orcid.org/0000-0003-3204-9311","observed_orcids":["https://orcid.org/0000-0003-3204-9311"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ana Cvejic","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040292172","display_name":"Nicole Soranzo","orcid":"https://orcid.org/0000-0003-1095-3852","observed_orcids":["https://orcid.org/0000-0003-1095-3852"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nicole Soranzo","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014699562","display_name":"Willem Hendrik Ouwehand","orcid":"https://orcid.org/0000-0002-7744-1790","observed_orcids":["https://orcid.org/0000-0002-7744-1790","https://orcid.org/0000-0001-5250-0160"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Willem H. Ouwehand","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]},{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036095832","display_name":"Hendrik G. Stunnenberg","orcid":"https://orcid.org/0000-0002-0066-1576","observed_orcids":["https://orcid.org/0000-0002-0066-1576"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Hendrik G. Stunnenberg","raw_affiliation_strings":["Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072577390","display_name":"Mattia Frontini","orcid":"https://orcid.org/0000-0001-8074-6299","observed_orcids":["https://orcid.org/0000-0001-8074-6299"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Mattia Frontini","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058403686","display_name":"Augusto Rendon","orcid":"https://orcid.org/0000-0001-8994-0039","observed_orcids":["https://orcid.org/0000-0001-8994-0039"]},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]},{"id":"https://openalex.org/I1307946715","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307946715"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Augusto Rendon","raw_affiliation_strings":["Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","Medical Research Council Biostatistics Unit, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK","National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Medical Research Council Biostatistics Unit, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK","institution_ids":["https://openalex.org/I4210134973","https://openalex.org/I90344618"]},{"raw_affiliation_string":"National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK","institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1307946715"]}]}],"institutions":[],"countries_distinct_count":8,"institutions_distinct_count":32,"corresponding_author_ids":["https://openalex.org/A5014699562","https://openalex.org/A5014988213","https://openalex.org/A5029443733","https://openalex.org/A5036095832","https://openalex.org/A5040292172","https://openalex.org/A5058403686","https://openalex.org/A5072577390","https://openalex.org/A5100432094"],"corresponding_institution_ids":["https://openalex.org/I125671874","https://openalex.org/I1303153112","https://openalex.org/I1307946715","https://openalex.org/I145872427","https://openalex.org/I241749","https://openalex.org/I2802476451","https://openalex.org/I4210134973","https://openalex.org/I90344618"],"apc_list":null,"apc_paid":null,"fwci":23.0428,"has_fulltext":true,"cited_by_count":304,"citation_normalized_percentile":{"value":0.99726609,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"345","issue":"6204","first_page":"1251033","last_page":"1251033"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.7749000191688538,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.7749000191688538,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.04479999840259552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.04390000179409981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.8190000057220459},{"id":"https://openalex.org/keywords/lineage-commitment","display_name":"lineage commitment","score":0.9070000052452087},{"id":"https://openalex.org/keywords/myeloid-differentiation","display_name":"myeloid differentiation","score":0.7390000224113464},{"id":"https://openalex.org/keywords/lymphoid-differentiation","display_name":"lymphoid differentiation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7799999713897705},{"id":"https://openalex.org/keywords/transcriptome","display_name":"transcriptome","score":0.546999990940094},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"non-coding RNA","score":0.6869999766349792},{"id":"https://openalex.org/keywords/nfib","display_name":"NFIB","score":0.656000018119812},{"id":"https://openalex.org/keywords/megakaryocyte-maturation","display_name":"megakaryocyte maturation","score":0.9670000076293945},{"id":"https://openalex.org/keywords/platelet-precursors","display_name":"platelet precursors","score":0.6679999828338623},{"id":"https://openalex.org/keywords/transcriptional-programs","display_name":"transcriptional programs","score":0.5920000076293945},{"id":"https://openalex.org/keywords/hematopoiesis","display_name":"hematopoiesis","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.7463984489440918},{"id":"https://openalex.org/C2781316041","wikidata":"https://www.wikidata.org/wiki/Q1230584","display_name":"Diversity (politics)","level":2,"score":0.684792697429657},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6224414110183716},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45783308148384094},{"id":"https://openalex.org/C15729860","wikidata":"https://www.wikidata.org/wiki/Q2329919","display_name":"Progenitor","level":4,"score":0.4449034333229065},{"id":"https://openalex.org/C3020437955","wikidata":"https://www.wikidata.org/wiki/Q7873","display_name":"Human blood","level":2,"score":0.42456763982772827},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4054758548736572},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3806667625904083},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27839356660842896},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22796308994293213},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.19807341694831848},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.13472285866737366},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.0945650041103363},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.07250732183456421}],"mesh":[{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034061","descriptor_name":"Thrombopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034061","descriptor_name":"Thrombopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034061","descriptor_name":"Thrombopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034061","descriptor_name":"Thrombopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034061","descriptor_name":"Thrombopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034061","descriptor_name":"Thrombopoiesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051839","descriptor_name":"NFI Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":16,"locations":[{"id":"doi:10.1126/science.1251033","doi":"https://doi.org/10.1126/science.1251033","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.1251033","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},{"id":"pmid:25258084","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25258084","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science (New York, N.Y.)","raw_type":"Journal Article"},{"id":"pmh:oai:recercat.cat:2072/357916","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10230/41853","pdf_url":null,"source":{"id":"https://openalex.org/S4306402147","display_name":"RECERCAT (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire/8c02d43c-f53a-4857-964d-4b9833a840b2","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4254742","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4254742/pdf/emss-60870.pdf","source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/246350","doi":null,"is_oa":true,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/246350","pdf_url":"https://www.repository.cam.ac.uk/bitstreams/1d0730cf-6f6a-4642-9d35-7891dcb294a9/download","source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:europepmc.org:3334583","doi":null,"is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4254742","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4254742","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4254742","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Science","raw_type":"Text"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10093617","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10093617/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Science , 345 (6204) , Article 1251033. (2014)","raw_type":"Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1456166","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1456166/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"SCIENCE , 345 (6204) 1580-+. (2014)","raw_type":"Article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:123456789/463576","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25258084","pdf_url":null,"source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Science, vol. 345 (6204), Art.No. 1251033, (1580-+)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repositori.upf.edu:10230/41853","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10230/41853","pdf_url":null,"source":{"id":"https://openalex.org/S4306402615","display_name":"Repositori digital de la UPF (Universitat Pompeu Fabra)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170486558","host_organization_name":"Universitat Pompeu Fabra","host_organization_lineage":["https://openalex.org/I170486558"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/133166","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/133166","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/d851ad9e-fe9f-4159-9ec7-916e4978aebb","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1983/d851ad9e-fe9f-4159-9ec7-916e4978aebb","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/d851ad9e-fe9f-4159-9ec7-916e4978aebb","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/d851ad9e-fe9f-4159-9ec7-916e4978aebb","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ueaeprints.uea.ac.uk:56426","doi":null,"is_oa":false,"landing_page_url":"https://ueaeprints.uea.ac.uk/id/eprint/56426/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400384","display_name":"UEA Digital Repository (University of East Anglia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1118541","host_organization_name":"University of East Anglia","host_organization_lineage":["https://openalex.org/I1118541"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/133166","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/133166","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Science, 345, 1251033","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pure.atira.dk:openaire/8c02d43c-f53a-4857-964d-4b9833a840b2","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4254742","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4254742/pdf/emss-60870.pdf","source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1243730289","display_name":"Ensembl","funder_award_id":"095908","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G1349290491","display_name":null,"funder_award_id":"RG/09/12/28096","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G2107972360","display_name":null,"funder_award_id":"MR/K006584/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2325242462","display_name":null,"funder_award_id":"EU-FP7","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2401487772","display_name":null,"funder_award_id":"ACF-2012-14-006","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G2807848565","display_name":"A BLUEPRINT of Haematopoietic Epigenomes","funder_award_id":"282510","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3713498729","display_name":"Epigenetics towards systems biology","funder_award_id":"257082","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3742120932","display_name":"NIHR Senior Investigator Award","funder_award_id":"NF-SI-0510-10214","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G4015493741","display_name":"Megakarocyte and Platelet Biology and Genomics","funder_award_id":"RP-PG-0310-1002","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G4321129689","display_name":null,"funder_award_id":"UK10K","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4567786232","display_name":"Pathophysiological characterization of megakaryopoiesis and platelet production: omics for thrombocytopenia and functional studies.","funder_award_id":"G0B1713N","funder_id":"https://openalex.org/F4320321730","funder_display_name":"Fonds Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G4612446324","display_name":null,"funder_award_id":"WT 098051","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4741688394","display_name":"Protein crystallography: development of new methods, and application to the study of pathogenesis.","funder_award_id":"082961","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4790079254","display_name":"The UK Blood Services Common Controls DNA Collection.","funder_award_id":"084183/Z/07/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4869868672","display_name":"Cellular Medicine at the Cambridge Institute for Medical Research.","funder_award_id":"100140","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4931427633","display_name":null,"funder_award_id":"C45041/A14953","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G4978210123","display_name":null,"funder_award_id":"MR/K024043/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5257833011","display_name":null,"funder_award_id":"09/12","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5725558014","display_name":null,"funder_award_id":"RP-PG-0310-1002","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G5983201483","display_name":null,"funder_award_id":"14953","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6564977220","display_name":null,"funder_award_id":"WT098051","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7452466554","display_name":"Predicting plaque rupture using invasive imaging and biomechanical modelling","funder_award_id":"FS/12/27/29405","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G7642076992","display_name":null,"funder_award_id":"WT098051","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G7658546326","display_name":null,"funder_award_id":"PG-0310-1002","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G7765784543","display_name":"NIHR Senior Investigator Award","funder_award_id":"NF-SI-0513-10151","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G7883946423","display_name":"The UK Blood Services Common Controls DNA Collection.","funder_award_id":"084183","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G84888450","display_name":null,"funder_award_id":"RG/09/12/28096","funder_id":"https://openalex.org/F4320310960","funder_display_name":"NHS Blood and Transplant"},{"id":"https://openalex.org/G8491121283","display_name":null,"funder_award_id":"WT091310","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G8527725420","display_name":"Premature cardiovascular disease and platelet quantitative traits: identification and functional characterisation of novel high-penetrance mutations and rare alleles","funder_award_id":"RG/09/012/28096","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G8538723892","display_name":null,"funder_award_id":"EU FP7","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G856282705","display_name":null,"funder_award_id":"MR/J011711/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G8678334142","display_name":null,"funder_award_id":"MR/K023489/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G8917412508","display_name":"Protein crystallography: development of new methods, and application to the study of pathogenesis.","funder_award_id":"082961/Z/07/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G969978795","display_name":null,"funder_award_id":"PG-0310-1002","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320310960","display_name":"NHS Blood and Transplant","ror":"https://ror.org/0227qpa16"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"},{"id":"https://openalex.org/F4320320283","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"},{"id":"https://openalex.org/F4320327336","display_name":"Vlaamse regering","ror":null},{"id":"https://openalex.org/F4320334175","display_name":"NIHR BioResource","ror":"https://ror.org/04dmgak75"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005806113.pdf","grobid_xml":"https://content.openalex.org/works/W2005806113.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W324535036","https://openalex.org/W1526134400","https://openalex.org/W1530336058","https://openalex.org/W1532846663","https://openalex.org/W1556198965","https://openalex.org/W1780633620","https://openalex.org/W1920059524","https://openalex.org/W1947358227","https://openalex.org/W1963521488","https://openalex.org/W1968569455","https://openalex.org/W1969876802","https://openalex.org/W1972259419","https://openalex.org/W1979193249","https://openalex.org/W1982202983","https://openalex.org/W1982460924","https://openalex.org/W1987374058","https://openalex.org/W1988479465","https://openalex.org/W1991599908","https://openalex.org/W2001672954","https://openalex.org/W2007202503","https://openalex.org/W2010847848","https://openalex.org/W2011920499","https://openalex.org/W2016273505","https://openalex.org/W2017777683","https://openalex.org/W2019552331","https://openalex.org/W2025648894","https://openalex.org/W2031558470","https://openalex.org/W2032424612","https://openalex.org/W2034691490","https://openalex.org/W2038181219","https://openalex.org/W2042323308","https://openalex.org/W2045264636","https://openalex.org/W2060741964","https://openalex.org/W2063530272","https://openalex.org/W2063643370","https://openalex.org/W2065695399","https://openalex.org/W2073889874","https://openalex.org/W2082462757","https://openalex.org/W2088549613","https://openalex.org/W2088583545","https://openalex.org/W2092582534","https://openalex.org/W2096441981","https://openalex.org/W2097184672","https://openalex.org/W2097392849","https://openalex.org/W2099328768","https://openalex.org/W2099477841","https://openalex.org/W2101291993","https://openalex.org/W2103373626","https://openalex.org/W2103441770","https://openalex.org/W2105694586","https://openalex.org/W2106678197","https://openalex.org/W2107060225","https://openalex.org/W2109936378","https://openalex.org/W2109963121","https://openalex.org/W2110335151","https://openalex.org/W2117688129","https://openalex.org/W2118669458","https://openalex.org/W2119326915","https://openalex.org/W2121678464","https://openalex.org/W2123830992","https://openalex.org/W2124985265","https://openalex.org/W2127779221","https://openalex.org/W2128646124","https://openalex.org/W2129271267","https://openalex.org/W2129916363","https://openalex.org/W2130912475","https://openalex.org/W2135898863","https://openalex.org/W2136352982","https://openalex.org/W2143980572","https://openalex.org/W2145191876","https://openalex.org/W2146849272","https://openalex.org/W2150098952","https://openalex.org/W2150892663","https://openalex.org/W2150951349","https://openalex.org/W2151462466","https://openalex.org/W2154699417","https://openalex.org/W2155766871","https://openalex.org/W2155804510","https://openalex.org/W2163370948","https://openalex.org/W2165397654","https://openalex.org/W2168133698","https://openalex.org/W2169456326","https://openalex.org/W2170282111","https://openalex.org/W2171777347","https://openalex.org/W2558692177","https://openalex.org/W2605068739","https://openalex.org/W2885727518","https://openalex.org/W4212920271","https://openalex.org/W4247053599"],"related_works":["https://openalex.org/W4393375503","https://openalex.org/W2084533426","https://openalex.org/W2043337239","https://openalex.org/W2019260118","https://openalex.org/W2026748421","https://openalex.org/W2762443209","https://openalex.org/W2578732716","https://openalex.org/W2966060845","https://openalex.org/W2057870358","https://openalex.org/W2889893284"],"abstract_inverted_index":{"Blood":[0],"cells":[1,6],"derive":[2],"from":[3,22],"hematopoietic":[4,26],"stem":[5],"through":[7],"stepwise":[8],"fating":[9,108],"events.":[10],"To":[11],"characterize":[12],"gene":[13],"expression":[14,45],"programs":[15],"driving":[16],"lineage":[17],"choice,":[18],"we":[19,63],"sequenced":[20],"RNA":[21],"eight":[23],"primary":[24],"human":[25],"progenitor":[27,113],"populations":[28],"representing":[29],"the":[30,36,105,115,122],"major":[31],"myeloid":[32],"commitment":[33],"stages":[34,58],"and":[35,49,69,126],"main":[37],"lymphoid":[38],"stage.":[39],"We":[40,83],"identified":[41],"extensive":[42],"cell":[43],"type-specific":[44],"changes:":[46],"6711":[47],"genes":[48,78],"10,724":[50],"transcripts,":[51],"enriched":[52,76],"in":[53,77,80,110],"non-protein-coding":[54],"elements":[55],"at":[56],"early":[57],"of":[59,97,107,117,124],"differentiation.":[60],"In":[61],"addition,":[62],"found":[64],"7881":[65],"novel":[66],"splice":[67],"junctions":[68],"2301":[70],"differentially":[71],"used":[72],"alternative":[73],"splicing":[74],"events,":[75],"involved":[79],"regulatory":[81],"processes.":[82],"demonstrated":[84],"experimentally":[85],"cell-specific":[86],"isoform":[87],"usage,":[88],"identifying":[89],"nuclear":[90],"factor":[91],"I/B":[92],"(NFIB)":[93],"as":[94],"a":[95],"regulator":[96],"megakaryocyte":[98],"maturation-the":[99],"platelet":[100],"precursor.":[101],"Our":[102],"data":[103],"highlight":[104],"complexity":[106],"events":[109],"closely":[111],"related":[112],"populations,":[114],"understanding":[116],"which":[118],"is":[119],"essential":[120],"for":[121],"advancement":[123],"transplantation":[125],"regenerative":[127],"medicine.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":37},{"year":2020,"cited_by_count":19},{"year":2019,"cited_by_count":26},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":49},{"year":2016,"cited_by_count":36},{"year":2015,"cited_by_count":26},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-19T09:35:57.686232","created_date":"2025-10-10T00:00:00"}
