{"id":"https://openalex.org/W2005708047","doi":"https://doi.org/10.1002/bms.1200010512","title":"Pyrolysis mass spectrometric studies on nucleic acids","display_name":"Pyrolysis mass spectrometric studies on nucleic acids","publication_year":1974,"publication_date":"1974-10-01","ids":{"openalex":"https://openalex.org/W2005708047","doi":"https://doi.org/10.1002/bms.1200010512","mag":"2005708047","pmid":"https://pubmed.ncbi.nlm.nih.gov/4465006"},"language":"en","primary_location":{"id":"doi:10.1002/bms.1200010512","doi":"https://doi.org/10.1002/bms.1200010512","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bms.1200010512","pdf_url":null,"source":{"id":"https://openalex.org/S37349105","display_name":"Journal of Mass Spectrometry","issn_l":"1076-5174","issn":["1076-5174","1096-9888"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Mass Spectrometry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028630730","display_name":"Maarten A. Posthumus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M. A. Posthumus","raw_affiliation_strings":["Laboratoria voor Analytische en Organische Scheikunde, Universiteit van Amsterdam, Amsterdam-1004, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoria voor Analytische en Organische Scheikunde, Universiteit van Amsterdam, Amsterdam-1004, The Netherlands","institution_ids":["https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111921867","display_name":"Nico M. M. Nibbering","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"N. M. M. Nibbering","raw_affiliation_strings":["Laboratoria voor Analytische en Organische Scheikunde, Universiteit van Amsterdam, Amsterdam-1004, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoria voor Analytische en Organische Scheikunde, Universiteit van Amsterdam, Amsterdam-1004, The Netherlands","institution_ids":["https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087288607","display_name":"A.J.H. Boerboom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. J. H. Boerboom","raw_affiliation_strings":["FOM-Instituut voor Atoom-en Molecuulfysica, Amsterdam-1006, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"FOM-Instituut voor Atoom-en Molecuulfysica, Amsterdam-1006, The Netherlands","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110086817","display_name":"H.\u2010R. Schulten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H.-R. Schulten","raw_affiliation_strings":["Institut fu\u0308r Physikalische Chemie der Universita\u0308t Bonn, 5300 Bonn, Germany","Institut f\u00fcr Physikalische Chemie der Universit\u00e4t Bonn, 5300 Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut fu\u0308r Physikalische Chemie der Universita\u0308t Bonn, 5300 Bonn, Germany","institution_ids":["https://openalex.org/I135140700"]},{"raw_affiliation_string":"Institut f\u00fcr Physikalische Chemie der Universit\u00e4t Bonn, 5300 Bonn, Germany","institution_ids":["https://openalex.org/I135140700"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":4.1681,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.94401655,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"1","issue":"5","first_page":"352","last_page":"357"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12166","display_name":"Ion-surface interactions and analysis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleic-acids","display_name":"nucleic acids","score":0.9120000004768372},{"id":"https://openalex.org/keywords/pyrolysis","display_name":"pyrolysis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/curie-point-pyrolysis","display_name":"Curie-point pyrolysis","score":0.8700000047683716},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.5540000200271606},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":1.0},{"id":"https://openalex.org/keywords/carbohydrate-moiety","display_name":"carbohydrate moiety","score":0.7409999966621399},{"id":"https://openalex.org/keywords/pyrolysis-mechanism","display_name":"pyrolysis mechanism","score":0.9200000166893005},{"id":"https://openalex.org/keywords/field-ionization-mass-spectrometry","display_name":"field ionization mass spectrometry","score":0.8360000252723694},{"id":"https://openalex.org/keywords/quadrupole-mass-spectrometry","display_name":"quadrupole mass spectrometry","score":0.9399999976158142}],"concepts":[{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.791182279586792},{"id":"https://openalex.org/C36759035","wikidata":"https://www.wikidata.org/wiki/Q176848","display_name":"Pyrolysis","level":2,"score":0.7348846197128296},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5201683044433594},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.47406619787216187},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.35784757137298584},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2648555338382721},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.24472841620445251},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12264353036880493}],"mesh":[{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/bms.1200010512","doi":"https://doi.org/10.1002/bms.1200010512","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bms.1200010512","pdf_url":null,"source":{"id":"https://openalex.org/S37349105","display_name":"Journal of Mass Spectrometry","issn_l":"1076-5174","issn":["1076-5174","1096-9888"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Mass Spectrometry","raw_type":"journal-article"},{"id":"pmid:4465006","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4465006","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical mass spectrometry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1970592256","https://openalex.org/W1978999811","https://openalex.org/W1986050205","https://openalex.org/W1987384443","https://openalex.org/W1992217824","https://openalex.org/W1993054586","https://openalex.org/W2003623527","https://openalex.org/W2047080537","https://openalex.org/W2052855697","https://openalex.org/W2064608420","https://openalex.org/W4234642027"],"related_works":["https://openalex.org/W2000906457","https://openalex.org/W1581801165","https://openalex.org/W1993054586","https://openalex.org/W2008239436","https://openalex.org/W2129594151","https://openalex.org/W1987384443","https://openalex.org/W1527730263","https://openalex.org/W1538358549","https://openalex.org/W1976448948","https://openalex.org/W2082517012"],"abstract_inverted_index":{"Two":[0],"different":[1],"mass":[2,23,30],"spectrometric":[3],"techniques":[4,37],"have":[5],"been":[6],"used":[7],"to":[8],"analyse":[9],"the":[10,49,53,61,65,69,87],"products":[11],"resulting":[12],"from":[13,64],"Curie-point":[14],"pyrolysis":[15,95],"of":[16,60,68,73,82],"nucleic":[17,70],"acids:":[18],"low":[19,50],"voltage":[20],"ionization":[21,29],"quadrupole":[22],"spectrometry":[24],"and":[25],"high":[26,54],"resolution":[27,51,55],"field":[28],"spectrometry.":[31],"The":[32],"spectra":[33,56],"obtained":[34],"with":[35,42],"both":[36],"are":[38,90,97],"in":[39],"good":[40],"agreement":[41],"one":[43],"another.":[44],"As":[45],"already":[46],"indicated":[47],"by":[48,80],"spectra,":[52],"proved":[57],"that":[58],"most":[59],"peaks":[62],"originate":[63],"carbohydrate":[66],"moiety":[67],"acid.":[71],"Micrograms":[72],"DNA/RNA":[74],"can":[75],"be":[76],"distinguished":[77],"very":[78],"easily":[79],"use":[81],"these":[83],"key":[84],"fragments,":[85],"although":[86],"bases":[88],"themselves":[89],"not":[91],"found.":[92],"Some":[93],"significant":[94],"mechanisms":[96],"proposed.":[98]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}