{"id":"https://openalex.org/W2005706416","doi":"https://doi.org/10.1371/journal.pone.0123328","title":"Regulation of Cadmium-Induced Proteomic and Metabolic Changes by 5-Aminolevulinic Acid in Leaves of Brassica napus L.","display_name":"Regulation of Cadmium-Induced Proteomic and Metabolic Changes by 5-Aminolevulinic Acid in Leaves of Brassica napus L.","publication_year":2015,"publication_date":"2015-04-24","ids":{"openalex":"https://openalex.org/W2005706416","doi":"https://doi.org/10.1371/journal.pone.0123328","mag":"2005706416","pmid":"https://pubmed.ncbi.nlm.nih.gov/25909456"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0123328","doi":"https://doi.org/10.1371/journal.pone.0123328","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0123328","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0123328&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0123328&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025914407","display_name":"Basharat Ali","orcid":"https://orcid.org/0000-0002-5965-7352","observed_orcids":["https://orcid.org/0000-0002-5965-7352"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Basharat Ali","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081751358","display_name":"Rafaqat A. Gill","orcid":"https://orcid.org/0000-0001-6553-9312","observed_orcids":["https://orcid.org/0000-0001-6553-9312"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rafaqat A. Gill","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088476571","display_name":"Su Yang","orcid":"https://orcid.org/0000-0001-8120-6016","observed_orcids":["https://orcid.org/0000-0001-8120-6016"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Su Yang","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090043530","display_name":"Muhammad Bilal Gill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Muhammad B. Gill","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029901039","display_name":"Muhammad Ahsan Farooq","orcid":"https://orcid.org/0000-0002-7183-2379","observed_orcids":["https://orcid.org/0000-0002-7183-2379"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Muhammad A. Farooq","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dan Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Liu","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048854268","display_name":"Muhammad Daud Khan","orcid":"https://orcid.org/0000-0001-8680-3020","observed_orcids":["https://orcid.org/0000-0001-8680-3020"]},"institutions":[{"id":"https://openalex.org/I178777954","display_name":"Kohat University of Science and Technology","ror":"https://ror.org/057d2v504","country_code":"PK","type":"education","lineage":["https://openalex.org/I178777954"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN","PK"],"is_corresponding":false,"raw_author_name":"Muhammad K. Daud","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China; Department of Biotechnology and Genetic Engineering, Kohat University of Science and Technology, Kohat 26000, Pakistan","Department of Biotechnology and Genetic Engineering, Kohat University of Science and Technology, Kohat 26000, Pakistan","Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China; Department of Biotechnology and Genetic Engineering, Kohat University of Science and Technology, Kohat 26000, Pakistan","institution_ids":["https://openalex.org/I178777954","https://openalex.org/I76130692"]},{"raw_affiliation_string":"Department of Biotechnology and Genetic Engineering, Kohat University of Science and Technology, Kohat 26000, Pakistan","institution_ids":["https://openalex.org/I178777954"]},{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086539587","display_name":"Shafaqat Ali","orcid":"https://orcid.org/0000-0002-3773-5196","observed_orcids":["https://orcid.org/0000-0002-3773-5196"]},"institutions":[{"id":"https://openalex.org/I194348271","display_name":"Government College University, Faisalabad","ror":"https://ror.org/051zgra59","country_code":"PK","type":"education","lineage":["https://openalex.org/I194348271"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Shafaqat Ali","raw_affiliation_strings":["Department of Environmental Sciences and Engineering, Government College University, Faisalabad 38000, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Sciences and Engineering, Government College University, Faisalabad 38000, Pakistan","institution_ids":["https://openalex.org/I194348271"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007686068","display_name":"Weijun Zhou","orcid":"https://orcid.org/0000-0002-1471-9644","observed_orcids":["https://orcid.org/0000-0002-1471-9644"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weijun Zhou","raw_affiliation_strings":["Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Crop Science and Zhejiang Key Laboratory of Crop Germplasm, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5007686068"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":12.5905,"has_fulltext":true,"cited_by_count":163,"citation_normalized_percentile":{"value":0.98807456,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"10","issue":"4","first_page":"e0123328","last_page":"e0123328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12407","display_name":"Plant Growth Enhancement Techniques","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10139","display_name":"Heavy metals in environment","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/5-aminolevulinic-acid","display_name":"5-aminolevulinic acid","score":0.9380000233650208},{"id":"https://openalex.org/keywords/cadmium-stress","display_name":"cadmium stress","score":0.871999979019165},{"id":"https://openalex.org/keywords/cadmium-tolerance","display_name":"cadmium tolerance","score":0.9079999923706055},{"id":"https://openalex.org/keywords/brassica-napus","display_name":"Brassica napus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/oilseed-rape","display_name":"oilseed rape","score":0.8999999761581421},{"id":"https://openalex.org/keywords/leaf-proteome","display_name":"leaf proteome","score":0.7559999823570251},{"id":"https://openalex.org/keywords/differentially-expressed-proteins","display_name":"differentially expressed proteins","score":0.6389999985694885},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.8370000123977661},{"id":"https://openalex.org/keywords/photosynthesis","display_name":"photosynthesis","score":0.8550000190734863},{"id":"https://openalex.org/keywords/carbohydrate-metabolism","display_name":"carbohydrate metabolism","score":0.703000009059906},{"id":"https://openalex.org/keywords/dihydrolipoyl-dehydrogenase","display_name":"dihydrolipoyl dehydrogenase","score":0.9620000123977661},{"id":"https://openalex.org/keywords/light-harvesting-complex","display_name":"light-harvesting complexes","score":0.6949999928474426},{"id":"https://openalex.org/keywords/thioredoxin-like-protein","display_name":"thioredoxin-like protein","score":0.8149999976158142},{"id":"https://openalex.org/keywords/proteasome","display_name":"proteasome","score":0.8820000290870667},{"id":"https://openalex.org/keywords/thiamine-biosynthesis","display_name":"thiamine biosynthesis","score":0.7429999709129333},{"id":"https://openalex.org/keywords/heavy-metal-stress","display_name":"heavy metal stress","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6289205551147461},{"id":"https://openalex.org/C27740335","wikidata":"https://www.wikidata.org/wiki/Q14878333","display_name":"Proteasome","level":2,"score":0.499467134475708},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.497682124376297},{"id":"https://openalex.org/C120763696","wikidata":"https://www.wikidata.org/wiki/Q419337","display_name":"Dihydrolipoamide dehydrogenase","level":4,"score":0.49267035722732544},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.4858226776123047},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.4675634801387787},{"id":"https://openalex.org/C2776747608","wikidata":"https://www.wikidata.org/wiki/Q58677","display_name":"Brassica","level":2,"score":0.4406253397464752},{"id":"https://openalex.org/C2779520027","wikidata":"https://www.wikidata.org/wiki/Q211118","display_name":"Protochlorophyllide","level":4,"score":0.4370185434818268},{"id":"https://openalex.org/C38062823","wikidata":"https://www.wikidata.org/wiki/Q3408228","display_name":"Ribosomal protein","level":5,"score":0.4236452579498291},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34478098154067993},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33928871154785156},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.30314141511917114},{"id":"https://openalex.org/C2776317432","wikidata":"https://www.wikidata.org/wiki/Q412547","display_name":"Dehydrogenase","level":3,"score":0.2222501039505005},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.20589572191238403},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17558953166007996},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.1395924687385559},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.1367780864238739},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.09810903668403625}],"mesh":[{"descriptor_ui":"D000622","descriptor_name":"Aminolevulinic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000622","descriptor_name":"Aminolevulinic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000622","descriptor_name":"Aminolevulinic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002104","descriptor_name":"Cadmium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002104","descriptor_name":"Cadmium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002104","descriptor_name":"Cadmium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029688","descriptor_name":"Brassica napus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1371/journal.pone.0123328","doi":"https://doi.org/10.1371/journal.pone.0123328","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0123328","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0123328&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmid:25909456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25909456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3388782","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4409391","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4409391","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4409391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:c64eb35769d7431b91a6986885e1fd56","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c64eb35769d7431b91a6986885e1fd56","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 10, Iss 4, p e0123328 (2015)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/2672161","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Regulation_of_Cadmium_Induced_Proteomic_and_Metabolic_Changes_by_5_Aminolevulinic_Acid_in_Leaves_of_i_Brassica_napus_i_L_/2672161","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.60692/2zbjv-sz096","doi":"https://doi.org/10.60692/2zbjv-sz096","is_oa":true,"landing_page_url":"https://doi.org/10.60692/2zbjv-sz096","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/77s3q-txt11","doi":"https://doi.org/10.60692/77s3q-txt11","is_oa":true,"landing_page_url":"https://doi.org/10.60692/77s3q-txt11","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0123328","doi":"https://doi.org/10.1371/journal.pone.0123328","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0123328","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0123328&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.6735000014305115}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.44999998807907104}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1400447819","display_name":null,"funder_award_id":"201303022","funder_id":"https://openalex.org/F4320335448","funder_display_name":"Special Fund for Agro-scientific Research in the Public Interest"},{"id":"https://openalex.org/G2936284601","display_name":"\u6839\u5bc4\u751f\u690d\u7269\u4e0e\u5bc4\u4e3b\u7684\u76f8\u4e92\u4f5c\u7528\u53ca\u5176\u5206\u5b50\u673a\u5236\u89e3\u6790","funder_award_id":"31170405","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4065415412","display_name":null,"funder_award_id":"2012C12902-1","funder_id":"https://openalex.org/F4320338110","funder_display_name":"Science and Technology Department of Zhejiang Province"},{"id":"https://openalex.org/G6057281577","display_name":null,"funder_award_id":"2011R50026-25","funder_id":"https://openalex.org/F4320338110","funder_display_name":"Science and Technology Department of Zhejiang Province"},{"id":"https://openalex.org/G6105926190","display_name":null,"funder_award_id":"201303022","funder_id":"https://openalex.org/F4320329854","funder_display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production"},{"id":"https://openalex.org/G7910836451","display_name":null,"funder_award_id":"31301678","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320329854","display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production","ror":"https://ror.org/02wwsr002"},{"id":"https://openalex.org/F4320335448","display_name":"Special Fund for Agro-scientific Research in the Public Interest","ror":null},{"id":"https://openalex.org/F4320338110","display_name":"Science and Technology Department of Zhejiang Province","ror":"https://ror.org/05yj3y977"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005706416.pdf","grobid_xml":"https://content.openalex.org/works/W2005706416.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W82252971","https://openalex.org/W172086352","https://openalex.org/W191793640","https://openalex.org/W320558138","https://openalex.org/W320599333","https://openalex.org/W1485732452","https://openalex.org/W1506360750","https://openalex.org/W1750990940","https://openalex.org/W1843885912","https://openalex.org/W1964184380","https://openalex.org/W1969233808","https://openalex.org/W1970346188","https://openalex.org/W1971763046","https://openalex.org/W1973090291","https://openalex.org/W1973630227","https://openalex.org/W1973712759","https://openalex.org/W1976716935","https://openalex.org/W1981055137","https://openalex.org/W1982653479","https://openalex.org/W1983729367","https://openalex.org/W1996772519","https://openalex.org/W2002807853","https://openalex.org/W2003744680","https://openalex.org/W2008366319","https://openalex.org/W2011922595","https://openalex.org/W2020922410","https://openalex.org/W2028823348","https://openalex.org/W2029456219","https://openalex.org/W2042359951","https://openalex.org/W2052480614","https://openalex.org/W2053325898","https://openalex.org/W2057433097","https://openalex.org/W2060979062","https://openalex.org/W2062251668","https://openalex.org/W2062932188","https://openalex.org/W2064230069","https://openalex.org/W2072944859","https://openalex.org/W2076109456","https://openalex.org/W2078394714","https://openalex.org/W2079836530","https://openalex.org/W2084043588","https://openalex.org/W2085919619","https://openalex.org/W2089997270","https://openalex.org/W2091232488","https://openalex.org/W2092375149","https://openalex.org/W2092831433","https://openalex.org/W2092937707","https://openalex.org/W2093806461","https://openalex.org/W2094401954","https://openalex.org/W2097812176","https://openalex.org/W2107277218","https://openalex.org/W2107581071","https://openalex.org/W2108973009","https://openalex.org/W2110856574","https://openalex.org/W2111568628","https://openalex.org/W2114615641","https://openalex.org/W2114842958","https://openalex.org/W2116788801","https://openalex.org/W2118577066","https://openalex.org/W2124283579","https://openalex.org/W2128635872","https://openalex.org/W2131019943","https://openalex.org/W2132495576","https://openalex.org/W2136855784","https://openalex.org/W2140725195","https://openalex.org/W2141381879","https://openalex.org/W2158666650","https://openalex.org/W2164112902","https://openalex.org/W2166964423","https://openalex.org/W6628835827"],"related_works":["https://openalex.org/W1018788396","https://openalex.org/W2052606001","https://openalex.org/W2253253352","https://openalex.org/W1988335372","https://openalex.org/W1043754368","https://openalex.org/W1876992098","https://openalex.org/W2142414952","https://openalex.org/W1991473745","https://openalex.org/W2134604440","https://openalex.org/W2013036004"],"abstract_inverted_index":{"It":[0],"is":[1,16],"evident":[2],"from":[3],"previous":[4],"reports":[5],"that":[6,61,88,122,178,208],"5-aminolevulinic":[7],"acid":[8],"(ALA),":[9],"like":[10],"other":[11],"known":[12],"plant":[13,254],"growth":[14],"regulators,":[15],"effective":[17],"in":[18,26,49,76,196,212,237,241,253],"countering":[19],"the":[20,40,66,77,92,103,114,141,180,197,210,228],"injurious":[21],"effects":[22],"of":[23,42,63,79,95,151,182,199,251],"heavy":[24],"metal-stress":[25],"oilseed":[27],"rape":[28],"(Brassica":[29],"napus":[30,51,81,243],"L.).":[31],"The":[32,85],"present":[33,115,229],"study":[34,230],"was":[35,176,205],"carried":[36],"out":[37],"to":[38,44,68,105,126],"explore":[39],"capability":[41],"ALA":[43,64,89,129,252],"improve":[45],"cadmium":[46],"(Cd2+)":[47],"tolerance":[48,240],"B.":[50,80,242],"through":[52],"physiological,":[53],"molecular,":[54],"and":[55,72,100,156,169,192,218,245],"proteomic":[56],"analytical":[57],"approaches.":[58],"Results":[59],"showed":[60],"application":[62],"helped":[65],"plants":[67],"adjust":[69],"Cd2+-induced":[70],"metabolic":[71],"photosynthetic":[73],"fluorescence":[74],"changes":[75],"leaves":[78,244],"under":[82,109,223],"Cd2+":[83,110,127,200,224,239],"stress.":[84,201,225],"data":[86],"revealed":[87],"treatment":[90],"enhanced":[91],"gene":[93],"expressions":[94],"antioxidant":[96],"enzyme":[97],"activities":[98],"substantially":[99],"could":[101],"increase":[102],"expression":[104],"a":[106,247],"certain":[107],"degree":[108],"stress":[111,145],"conditions.":[112],"In":[113,202],"study,":[116],"34":[117],"protein":[118,157],"spots":[119],"were":[120,135,166,172],"identified":[121],"differentially":[123],"regulated":[124,137],"due":[125],"and/or":[128],"treatments.":[130],"Among":[131],"them,":[132],"18":[133,161],"proteins":[134,142,165,171,195,222],"significantly":[136,167],"by":[138],"ALA,":[139],"including":[140],"associated":[143],"with":[144],"related,":[146],"carbohydrate":[147],"metabolism,":[148],"catalysis,":[149],"dehydration":[150],"damaged":[152],"protein,":[153,214],"CO2":[154],"assimilation/photosynthesis":[155],"synthesis/regulation.":[158],"From":[159],"these":[160],"ALA-regulated":[162],"proteins,":[163],"12":[164],"down-regulated":[168],"6":[170,191],"up-regulated.":[173],"Interestingly,":[174],"it":[175,204],"observed":[177,207],"ALA-induced":[179,209,238],"up-regulation":[181],"dihydrolipoyl":[183],"dehydrogenase,":[184],"light":[185,232],"harvesting":[186],"complex":[187],"photo-system":[188],"II":[189],"subunit":[190],"30S":[193],"ribosomal":[194],"presence":[198],"addition,":[203],"also":[206],"down-regulation":[211],"thioredoxin-like":[213],"2,":[215],"3-bisphosphoglycerate,":[216],"proteasome":[217],"thiamine":[219],"thiazole":[220],"synthase":[221],"Taken":[226],"together,":[227],"sheds":[231],"on":[233],"molecular":[234],"mechanisms":[235],"involved":[236],"suggests":[246],"more":[248],"active":[249],"involvement":[250],"physiological":[255],"processes":[256],"than":[257],"previously":[258],"proposed.":[259]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":30},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":21},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}