{"id":"https://openalex.org/W2005703566","doi":"https://doi.org/10.1111/j.1432-1033.1988.tb14262.x","title":"Opposite regulation of the mRNAs for parvalbumin and p19/6.8 in myotonic mouse muscle","display_name":"Opposite regulation of the mRNAs for parvalbumin and p19/6.8 in myotonic mouse muscle","publication_year":1988,"publication_date":"1988-09-01","ids":{"openalex":"https://openalex.org/W2005703566","doi":"https://doi.org/10.1111/j.1432-1033.1988.tb14262.x","mag":"2005703566","pmid":"https://pubmed.ncbi.nlm.nih.gov/3138114"},"language":"en","primary_location":{"id":"doi:10.1111/j.1432-1033.1988.tb14262.x","doi":"https://doi.org/10.1111/j.1432-1033.1988.tb14262.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1988.tb14262.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035140588","display_name":"F.W. Kluxen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Franz\u2010Werner KLUXEN","raw_affiliation_strings":["Developmental Biology Unit, University of Bielefeld, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Developmental Biology Unit, University of Bielefeld, Federal Republic of Germany","institution_ids":["https://openalex.org/I20121455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111472553","display_name":"Fritz Sch\u00f6ffl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fritz SCH\u00d6FFL","raw_affiliation_strings":["Genetics Unit, University of Bielefeld"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Unit, University of Bielefeld","institution_ids":["https://openalex.org/I20121455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078423327","display_name":"Martin Werner Berchtold","orcid":"https://orcid.org/0000-0001-8995-9047","observed_orcids":["https://orcid.org/0000-0001-8995-9047"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Martin W. BERCHTOLD","raw_affiliation_strings":["Insitute of Pharmacology and Biochemistry, University of Zu\u0308rich-Irchel","Insitute of Pharmacology and Biochemistry, University of Z\u00fcrich\u2010Irchel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insitute of Pharmacology and Biochemistry, University of Zu\u0308rich-Irchel","institution_ids":["https://openalex.org/I202697423"]},{"raw_affiliation_string":"Insitute of Pharmacology and Biochemistry, University of Z\u00fcrich\u2010Irchel","institution_ids":["https://openalex.org/I202697423"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5097799368","display_name":"Harald JOCKSUCH","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Harald JOCKSUCH","raw_affiliation_strings":["Development Biology Unit, W7,and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Development Biology Unit, W7,and","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5097799368"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7567,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.69279352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"176","issue":"1","first_page":"153","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8687000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8687000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.12479999661445618,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myotonia","display_name":"myotonia","score":0.8429999947547913},{"id":"https://openalex.org/keywords/parvalbumin","display_name":"parvalbumin","score":0.843999981880188},{"id":"https://openalex.org/keywords/mrna-levels","display_name":"mRNA levels","score":0.5609999895095825},{"id":"https://openalex.org/keywords/calcium-binding-proteins","display_name":"calcium-binding proteins","score":0.7950000166893005},{"id":"https://openalex.org/keywords/fast-muscle","display_name":"fast muscle","score":0.7429999709129333},{"id":"https://openalex.org/keywords/slow-muscle-fibers","display_name":"slow muscle fibers","score":0.7900000214576721},{"id":"https://openalex.org/keywords/calmodulin","display_name":"calmodulin","score":0.8270000219345093},{"id":"https://openalex.org/keywords/chloride-conductance","display_name":"chloride conductance","score":0.8980000019073486},{"id":"https://openalex.org/keywords/tocainide","display_name":"tocainide","score":0.8960000276565552},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C141547260","wikidata":"https://www.wikidata.org/wiki/Q2720322","display_name":"Parvalbumin","level":2,"score":0.963336169719696},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.7193822860717773},{"id":"https://openalex.org/C29688787","wikidata":"https://www.wikidata.org/wiki/Q409145","display_name":"Calmodulin","level":3,"score":0.6488121747970581},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5881600379943848},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5648691058158875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4940088391304016},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4821721911430359},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.449161171913147},{"id":"https://openalex.org/C2780304057","wikidata":"https://www.wikidata.org/wiki/Q1277793","display_name":"Myotonia","level":3,"score":0.4351693391799927},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21278566122055054},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15383845567703247},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1036929190158844},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09311649203300476},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07408532500267029},{"id":"https://openalex.org/C2778063965","wikidata":"https://www.wikidata.org/wiki/Q1860507","display_name":"Myotonic dystrophy","level":2,"score":0.07066220045089722}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007120","descriptor_name":"Immunochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007120","descriptor_name":"Immunochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007120","descriptor_name":"Immunochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009222","descriptor_name":"Myotonia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009222","descriptor_name":"Myotonia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009222","descriptor_name":"Myotonia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009222","descriptor_name":"Myotonia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009222","descriptor_name":"Myotonia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009222","descriptor_name":"Myotonia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016677","descriptor_name":"Tocainide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016677","descriptor_name":"Tocainide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016677","descriptor_name":"Tocainide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1432-1033.1988.tb14262.x","doi":"https://doi.org/10.1111/j.1432-1033.1988.tb14262.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1988.tb14262.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:3138114","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3138114","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1482317169","https://openalex.org/W1531587872","https://openalex.org/W1596012657","https://openalex.org/W1603573575","https://openalex.org/W1606423922","https://openalex.org/W1651280426","https://openalex.org/W1970403529","https://openalex.org/W1970412867","https://openalex.org/W1979311249","https://openalex.org/W1981595546","https://openalex.org/W2004073374","https://openalex.org/W2010070716","https://openalex.org/W2011485659","https://openalex.org/W2014669590","https://openalex.org/W2019062170","https://openalex.org/W2021504472","https://openalex.org/W2035909914","https://openalex.org/W2036260475","https://openalex.org/W2043867671","https://openalex.org/W2057501689","https://openalex.org/W2060333964","https://openalex.org/W2061355493","https://openalex.org/W2066094116","https://openalex.org/W2072834895","https://openalex.org/W2087909154","https://openalex.org/W2092132336","https://openalex.org/W2094869415","https://openalex.org/W2100837269","https://openalex.org/W2103394128","https://openalex.org/W2114482218","https://openalex.org/W2118553083","https://openalex.org/W2120759692","https://openalex.org/W2131183108","https://openalex.org/W2138825060","https://openalex.org/W2139864850","https://openalex.org/W2222043223","https://openalex.org/W2286503627"],"related_works":["https://openalex.org/W2054364273","https://openalex.org/W2018283369","https://openalex.org/W2219043996","https://openalex.org/W2021113401","https://openalex.org/W2057746300","https://openalex.org/W1965586428","https://openalex.org/W4231342599","https://openalex.org/W1993973446","https://openalex.org/W1976495423","https://openalex.org/W2940942137"],"abstract_inverted_index":{"The":[0,144],"gene":[1],"mutation":[2],"in":[3,62,97,119,128,154,158,183],"the":[4,19,25,45,55,74,83,86,94,98,104,110,159,167,177,181,186],"mouse,":[5],"'arrested":[6],"development":[7],"of":[8,15,18,27,54,64,73,109,185],"righting":[9],"response',":[10],"adr,":[11],"causes":[12],"a":[13,51,137,142,174],"defect":[14],"chloride":[16],"conductance":[17],"muscle":[20,122,155,184],"fibre":[21],"membrane":[22],"leading":[23],"to":[24],"symptoms":[26],"myotonia":[28],"[Mehrke,":[29],"G.,":[30],"Brinkmeier,":[31],"H.":[32,35],"and":[33,116,123,156,190],"Jockusch,":[34],"(1988)":[36],"Muscle":[37],"&":[38],"Nerve":[39],"11,":[40],"440-446].":[41],"In":[42,70,92],"fast":[43,71,121],"muscle,":[44],"myotonic":[46,65],"phenotype":[47],"is":[48],"accompanied":[49],"by":[50,103,133,166],"drastic":[52],"reduction":[53,108],"Ca2+-binding":[56,149],"protein,":[57,88,150],"parvalbumin.":[58],"Messenger":[59],"RNA":[60],"levels":[61,127,182],"organs":[63],"(ADR)":[66],"mice":[67,171],"were":[68,131,172,192],"analysed.":[69],"muscles":[72],"mutant,":[75],"in-vitro-translatable":[76],"parvalbumin":[77,95,112,125,139,189],"mRNA":[78,84,96,113,126,145],"was":[79,90,100,152,164],"strongly":[80],"reduced,":[81],"whereas":[82],"for":[85,147,188],"slow-muscle-specific":[87],"p19/6.8,":[89],"increased.":[91],"contrast,":[93],"cerebellum":[99],"not":[101],"affected":[102],"adr":[105],"mutation.":[106,168],"A":[107],"two":[111],"species":[114],"(700":[115],"1100":[117],"nucleotides)":[118],"ADR":[120],"unaltered":[124],"mutant":[129],"cerebella":[130],"demonstrated":[132],"cDNA/mRNA":[134],"hybridisation,":[135],"using":[136],"rat":[138],"cDNA":[140],"as":[141],"probe.":[143],"level":[146],"another":[148],"calmodulin,":[151],"low":[153],"high":[157],"central":[160],"nervous":[161],"system":[162],"but":[163],"unaffected":[165],"When":[169],"adr/adr":[170],"fed":[173],"diet":[175],"containing":[176],"membrane-stabilising":[178],"drug,":[179],"tocainide,":[180],"mRNAs":[187],"p19/6.8":[191],"partially":[193],"normalised.":[194]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}