{"id":"https://openalex.org/W2005686740","doi":"https://doi.org/10.1088/0031-9155/44/6/308","title":"Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy","display_name":"Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W2005686740","doi":"https://doi.org/10.1088/0031-9155/44/6/308","mag":"2005686740","pmid":"https://pubmed.ncbi.nlm.nih.gov/10498522"},"language":"en","primary_location":{"id":"doi:10.1088/0031-9155/44/6/308","doi":"https://doi.org/10.1088/0031-9155/44/6/308","is_oa":false,"landing_page_url":"https://doi.org/10.1088/0031-9155/44/6/308","pdf_url":null,"source":{"id":"https://openalex.org/S20241394","display_name":"Physics in Medicine and Biology","issn_l":"0031-9155","issn":["0031-9155","1361-6560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in Medicine and Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://escholarship.org/uc/item/92x282f9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079919056","display_name":"Sergio Fantini","orcid":"https://orcid.org/0000-0001-5116-525X","observed_orcids":["https://orcid.org/0000-0001-5116-525X"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sergio Fantini","raw_affiliation_strings":["Department of Physics, University of Illinois at Urbana-Champaign, Urbana 61801-3080, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of Illinois at Urbana-Champaign, Urbana 61801-3080, USA","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024769880","display_name":"Dennis M. Hueber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124710","display_name":"International Space Station","ror":"https://ror.org/02s42x260","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800419965","https://openalex.org/I4210124710","https://openalex.org/I4210124779"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis Hueber","raw_affiliation_strings":["ISS, Incorporated, 2604 North Mattis Avenue, Champaign, IL 61821, USA","ISS, Incorporated, 2604 North Mattis #N#Avenue, Champaign, IL 61821, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISS, Incorporated, 2604 North Mattis Avenue, Champaign, IL 61821, USA","institution_ids":["https://openalex.org/I4210124710"]},{"raw_affiliation_string":"ISS, Incorporated, 2604 North Mattis #N#Avenue, Champaign, IL 61821, USA","institution_ids":["https://openalex.org/I4210124710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034890407","display_name":"Maria Angela Franceschini","orcid":"https://orcid.org/0000-0001-6758-423X","observed_orcids":["https://orcid.org/0000-0001-6758-423X"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Angela Franceschini","raw_affiliation_strings":["Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, IL 61801-3080, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, IL 61801-3080, USA","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005039590","display_name":"Enrico Gratton","orcid":"https://orcid.org/0000-0002-6450-7391","observed_orcids":["https://orcid.org/0000-0002-6450-7391"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Enrico Gratton","raw_affiliation_strings":["Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, IL 61801-3080, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, IL 61801-3080, USA","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083799684","display_name":"Warren Rosenfeld","orcid":"https://orcid.org/0000-0003-1660-774X","observed_orcids":["https://orcid.org/0000-0003-1660-774X"]},"institutions":[{"id":"https://openalex.org/I1289739345","display_name":"Winthrop-University Hospital","ror":"https://ror.org/03eksqx74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289739345"]},{"id":"https://openalex.org/I1327163397","display_name":"State University of New York","ror":"https://ror.org/01q1z8k08","country_code":"US","type":"education","lineage":["https://openalex.org/I1327163397"]},{"id":"https://openalex.org/I4210087560","display_name":"Stony Brook School","ror":"https://ror.org/003wx9n05","country_code":"US","type":"education","lineage":["https://openalex.org/I4210087560"]},{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Warren Rosenfeld","raw_affiliation_strings":["Departments of Obstetrics/Gynecology and Pediatrics, Winthrop University Hospital, State University of New York, Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA","Departments of Obstetrics/Gynecology and #N#Pediatrics,#N#Winthrop University Hospital,#N#State University of New York,#N#Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics/Gynecology and Pediatrics, Winthrop University Hospital, State University of New York, Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA","institution_ids":["https://openalex.org/I1289739345","https://openalex.org/I4210087560","https://openalex.org/I59553526"]},{"raw_affiliation_string":"Departments of Obstetrics/Gynecology and #N#Pediatrics,#N#Winthrop University Hospital,#N#State University of New York,#N#Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA","institution_ids":["https://openalex.org/I1289739345","https://openalex.org/I1327163397","https://openalex.org/I4210087560","https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111734209","display_name":"Phillip G. Stubblefield","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1286490081","display_name":"Boston Medical Center","ror":"https://ror.org/010b9wj87","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1286490081"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phillip G Stubblefield","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Boston University School of Medicine, 1 Boston Medical Center Place, Boston, MA 02118, USA","Department of Obstetrics and Gynecology,#N#Boston University School of Medicine,#N#1 Boston Medical Center Place,#N#Boston, MA 02118, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Boston University School of Medicine, 1 Boston Medical Center Place, Boston, MA 02118, USA","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology,#N#Boston University School of Medicine,#N#1 Boston Medical Center Place,#N#Boston, MA 02118, USA","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054637119","display_name":"Dev Maulik","orcid":"https://orcid.org/0000-0002-5547-5009","observed_orcids":["https://orcid.org/0000-0002-5547-5009"]},"institutions":[{"id":"https://openalex.org/I1289739345","display_name":"Winthrop-University Hospital","ror":"https://ror.org/03eksqx74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289739345"]},{"id":"https://openalex.org/I1327163397","display_name":"State University of New York","ror":"https://ror.org/01q1z8k08","country_code":"US","type":"education","lineage":["https://openalex.org/I1327163397"]},{"id":"https://openalex.org/I4210087560","display_name":"Stony Brook School","ror":"https://ror.org/003wx9n05","country_code":"US","type":"education","lineage":["https://openalex.org/I4210087560"]},{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dev Maulik","raw_affiliation_strings":["Departments of Obstetrics/Gynecology and Pediatrics, Winthrop University Hospital, State University of New York, Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA","Departments of Obstetrics/Gynecology and #N#Pediatrics,#N#Winthrop University Hospital,#N#State University of New York,#N#Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics/Gynecology and Pediatrics, Winthrop University Hospital, State University of New York, Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA","institution_ids":["https://openalex.org/I1289739345","https://openalex.org/I4210087560","https://openalex.org/I59553526"]},{"raw_affiliation_string":"Departments of Obstetrics/Gynecology and #N#Pediatrics,#N#Winthrop University Hospital,#N#State University of New York,#N#Stony Brook School of Medicine, 259 First Street, Mineola, NY 11501, USA","institution_ids":["https://openalex.org/I1289739345","https://openalex.org/I1327163397","https://openalex.org/I4210087560","https://openalex.org/I59553526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017136128","display_name":"Miljan R. Stankovic","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1286490081","display_name":"Boston Medical Center","ror":"https://ror.org/010b9wj87","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1286490081"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miljan R Stankovic","raw_affiliation_strings":["Boston Medical Center Place, Boston, MA 02118, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston Medical Center Place, Boston, MA 02118, USA","institution_ids":["https://openalex.org/I1286490081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3325,"currency":"USD","value_usd":3325},"apc_paid":null,"fwci":7.1257,"has_fulltext":false,"cited_by_count":275,"citation_normalized_percentile":{"value":0.97459493,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"44","issue":"6","first_page":"1543","last_page":"1563"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reduced-scattering-coefficient","display_name":"reduced scattering coefficient","score":0.9919999837875366},{"id":"https://openalex.org/keywords/frequency-domain-spectroscopy","display_name":"frequency domain spectroscopy","score":0.7820000052452087},{"id":"https://openalex.org/keywords/continuous-wave-spectroscopy","display_name":"continuous-wave spectroscopy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/carotid-occlusion","display_name":"carotid artery occlusion","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cerebral-hemodynamics","display_name":"cerebral hemodynamics","score":0.734000027179718},{"id":"https://openalex.org/keywords/cerebral-oxygenation","display_name":"cerebral oxygenation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/motion-artifacts","display_name":"motion artifacts","score":0.9039999842643738}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.513046145439148},{"id":"https://openalex.org/C32891209","wikidata":"https://www.wikidata.org/wiki/Q483666","display_name":"Spectroscopy","level":2,"score":0.5012223720550537},{"id":"https://openalex.org/C2779914510","wikidata":"https://www.wikidata.org/wiki/Q193840","display_name":"Asphyxia","level":2,"score":0.48016658425331116},{"id":"https://openalex.org/C19118579","wikidata":"https://www.wikidata.org/wiki/Q786423","display_name":"Frequency domain","level":2,"score":0.4748111963272095},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.465564489364624},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.3937772214412689},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.38703447580337524},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24332061409950256},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.22979521751403809},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.19029322266578674},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.10672903060913086},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001237","descriptor_name":"Asphyxia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016893","descriptor_name":"Carotid Stenosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1088/0031-9155/44/6/308","doi":"https://doi.org/10.1088/0031-9155/44/6/308","is_oa":false,"landing_page_url":"https://doi.org/10.1088/0031-9155/44/6/308","pdf_url":null,"source":{"id":"https://openalex.org/S20241394","display_name":"Physics in Medicine and Biology","issn_l":"0031-9155","issn":["0031-9155","1361-6560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in Medicine and Biology","raw_type":"journal-article"},{"id":"pmid:10498522","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10498522","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in medicine and biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.701.5191","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.701.5191","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.nmr.mgh.harvard.edu/optics/PDF/Fantini_PMB_44_1543_1999.pdf","raw_type":"text"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt92x282f9","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/92x282f9","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Physics in medicine and biology, vol 44, iss 6","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt92x282f9","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/92x282f9","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Physics in Medicine and Biology, vol 44, iss 6","raw_type":"article"},{"id":"pmh:qt92x282f9","doi":null,"is_oa":true,"landing_page_url":"http://www.escholarship.org/uc/item/92x282f9","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Fantini, S; Hueber, D; Franceschini, MA; Gratton, E; Rosenfeld, W; Stubblefield, PG; \u00c2\u00a0et al.(1999). Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy. Physics in Medicine and Biology, 44(6), 1543 - 1563. doi: 10.1088/0031-9155/44/6/308. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/92x282f9","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:escholarship.org/ark:/13030/qt92x282f9","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/92x282f9","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Physics in medicine and biology, vol 44, iss 6","raw_type":"article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2157469359","display_name":"VASCULAR INSUFFICIENCY IN PERIPHERAL TISSUE","funder_award_id":"R01RR010966","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G8617650704","display_name":"OPTICAL IMAGING OF THICK TISSUES","funder_award_id":"R01CA057032","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1521108077","https://openalex.org/W1596077691","https://openalex.org/W1838595539","https://openalex.org/W1887566604","https://openalex.org/W1905603695","https://openalex.org/W1918103124","https://openalex.org/W1966451862","https://openalex.org/W1973638771","https://openalex.org/W1974071367","https://openalex.org/W1976217583","https://openalex.org/W1981097671","https://openalex.org/W1990445184","https://openalex.org/W1991550546","https://openalex.org/W1998055482","https://openalex.org/W1998247126","https://openalex.org/W1999927192","https://openalex.org/W2000529812","https://openalex.org/W2007198191","https://openalex.org/W2010411231","https://openalex.org/W2014885692","https://openalex.org/W2017143976","https://openalex.org/W2020528079","https://openalex.org/W2022893743","https://openalex.org/W2025492305","https://openalex.org/W2035055923","https://openalex.org/W2035465538","https://openalex.org/W2042295435","https://openalex.org/W2047897461","https://openalex.org/W2050973816","https://openalex.org/W2057377618","https://openalex.org/W2057803819","https://openalex.org/W2059002523","https://openalex.org/W2060114336","https://openalex.org/W2060702906","https://openalex.org/W2061987937","https://openalex.org/W2072426302","https://openalex.org/W2074948889","https://openalex.org/W2075306607","https://openalex.org/W2080399942","https://openalex.org/W2082418745","https://openalex.org/W2083987305","https://openalex.org/W2085624360","https://openalex.org/W2090816603","https://openalex.org/W2091115969","https://openalex.org/W2094780155","https://openalex.org/W2094961471","https://openalex.org/W2096857833","https://openalex.org/W2102352741","https://openalex.org/W2115190434","https://openalex.org/W2116495081","https://openalex.org/W2137523819","https://openalex.org/W2139684042","https://openalex.org/W2147917558","https://openalex.org/W2149119632","https://openalex.org/W2150476025","https://openalex.org/W2155460883","https://openalex.org/W2159198745","https://openalex.org/W2186645054","https://openalex.org/W2254999223","https://openalex.org/W2281843140","https://openalex.org/W2418451089","https://openalex.org/W3181029340"],"related_works":["https://openalex.org/W2104009306","https://openalex.org/W7099554889","https://openalex.org/W2155145086","https://openalex.org/W2129051806","https://openalex.org/W2290264704","https://openalex.org/W7095252244","https://openalex.org/W2054168361","https://openalex.org/W2418451089","https://openalex.org/W7097227982","https://openalex.org/W2145742694"],"abstract_inverted_index":{"We":[0,254],"have":[1,170],"used":[2],"continuous-wave":[3],"(CW)":[4],"and":[5,20,26,44,60,68,89,98,116,125,134,181,186,215,262],"frequency-domain":[6,71,129],"spectroscopy":[7,72],"to":[8,78,152,245],"investigate":[9],"the":[10,14,48,53,57,79,106,165,177,182,193,197,206,212,225,250,266,272,275],"optical":[11,42,49,167,179,208],"properties":[12,180],"of":[13,47,56,82,85,105,146,155,196,205],"newborn":[15,28],"piglet":[16,276],"brain":[17,58,111,118,150,161,273],"in":[18,95,249,265,271],"vivo":[19],"non-invasively.":[21],"Three":[22],"anaesthetized,":[23],"intubated,":[24],"ventilated":[25],"instrumented":[27],"piglets":[29],"were":[30,131],"placed":[31],"into":[32],"a":[33,103,144,153,173,189,229],"stereotaxic":[34],"instrument":[35],"for":[36],"optimal":[37],"experimental":[38],"stability,":[39],"reproducible":[40],"probe-to-scalp":[41],"contact":[43],"3D":[45],"adjustment":[46],"probe.":[50],"By":[51],"measuring":[52],"absolute":[54,74],"values":[55,141],"absorption":[59],"reduced":[61,238,267],"scattering":[62,268],"coefficients":[63],"at":[64],"two":[65],"wavelengths":[66],"(758":[67],"830":[69],"nm),":[70],"provided":[73],"readings":[75,81,248],"(in":[76],"contrast":[77],"relative":[80,247],"CW":[83,166],"spectroscopy)":[84],"cerebral":[86,96,122,139,178,207],"haemoglobin":[87,123],"concentration":[88],"saturation":[90,124,140],"during":[91],"experimentally":[92],"induced":[93],"perturbations":[94,101],"haemodynamics":[97],"oxygenation.":[99],"Such":[100],"included":[102],"modulation":[104],"inspired":[107],"oxygen":[108],"concentration,":[109,126],"transient":[110,149,160],"asphyxia,":[112],"carotid":[113],"artery":[114],"occlusion":[115],"terminal":[117],"asphyxia.":[119],"The":[120,138,203],"baseline":[121],"measured":[127,270],"with":[128,211,216],"spectroscopy,":[130],"about":[132],"60%":[133],"42":[135],"microM":[136],"respectively.":[137],"ranged":[142],"from":[143,159,228,242],"minimum":[145],"17%":[147],"(during":[148,157],"asphyxia)":[151],"maximum":[154],"80%":[156],"recovery":[158],"asphyxia).":[162],"To":[163],"analyse":[164],"data,":[168],"we":[169],"(a)":[171],"derived":[172],"mathematical":[174],"relationship":[175],"between":[176],"differential":[183],"pathlength":[184],"factor":[185],"(b)":[187],"introduced":[188],"method":[190],"based":[191],"on":[192],"spatial":[194],"dependence":[195],"detected":[198],"intensity":[199,226],"(dc":[200],"slope":[201,252],"method).":[202],"analysis":[204],"signals":[209],"associated":[210],"arterial":[213],"pulse":[214],"respiration":[217],"demonstrates":[218],"that":[219],"motion":[220],"artefacts":[221,234],"can":[222,235],"significantly":[223],"affect":[224],"recorded":[227],"single":[230],"optode":[231],"pair.":[232],"Motion":[233],"be":[236],"strongly":[237],"by":[239],"combining":[240],"data":[241],"multiple":[243],"optodes":[244],"provide":[246],"dc":[251],"method.":[253],"also":[255],"report":[256],"significant":[257],"biphasic":[258],"changes":[259],"(initial":[260],"decrease":[261],"successive":[263],"increase)":[264],"coefficient":[269],"after":[274],"had":[277],"been":[278],"sacrificed.":[279]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":22}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}