{"id":"https://openalex.org/W2005644611","doi":"https://doi.org/10.1002/ajhb.1310030105","title":"Differentially delayed development in the hand\u2013wrist skeletons of children with cystic fibrosis: Round versus tubular bones","display_name":"Differentially delayed development in the hand\u2013wrist skeletons of children with cystic fibrosis: Round versus tubular bones","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W2005644611","doi":"https://doi.org/10.1002/ajhb.1310030105","mag":"2005644611","pmid":"https://pubmed.ncbi.nlm.nih.gov/28520312"},"language":"en","primary_location":{"id":"doi:10.1002/ajhb.1310030105","doi":"https://doi.org/10.1002/ajhb.1310030105","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ajhb.1310030105","pdf_url":null,"source":{"id":"https://openalex.org/S179381287","display_name":"American Journal of Human Biology","issn_l":"1042-0533","issn":["1042-0533","1520-6300"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Human Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039056655","display_name":"Michael C. Mahaney","orcid":"https://orcid.org/0000-0002-1341-3950","observed_orcids":["https://orcid.org/0000-0002-1341-3950"]},"institutions":[{"id":"https://openalex.org/I79817857","display_name":"University of Guelph","ror":"https://ror.org/01r7awg59","country_code":"CA","type":"education","lineage":["https://openalex.org/I79817857"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Michael C. Mahaney","raw_affiliation_strings":["School of Human Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Human Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada","institution_ids":["https://openalex.org/I79817857"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5039056655"],"corresponding_institution_ids":["https://openalex.org/I79817857"],"apc_list":{"value":4550,"currency":"USD","value_usd":4550},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.18365462,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"3","issue":"1","first_page":"17","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10992","display_name":"Forensic Anthropology and Bioarchaeology Studies","score":0.057100001722574234,"subfield":{"id":"https://openalex.org/subfields/1204","display_name":"Archeology"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13107","display_name":"Congenital limb and hand anomalies","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1309","display_name":"Developmental Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":1.0},{"id":"https://openalex.org/keywords/skeletal-maturation","display_name":"skeletal maturation","score":0.7630000114440918},{"id":"https://openalex.org/keywords/bone-age-delay","display_name":"bone age delay","score":0.8550000190734863},{"id":"https://openalex.org/keywords/hand-wrist-radiographs","display_name":"hand-wrist radiographs","score":0.949999988079071},{"id":"https://openalex.org/keywords/carpal-bones","display_name":"carpal bones","score":0.8080000281333923},{"id":"https://openalex.org/keywords/tubular-bones","display_name":"tubular bones","score":0.9710000157356262},{"id":"https://openalex.org/keywords/radius-and-ulna","display_name":"radius and ulna","score":0.8450000286102295},{"id":"https://openalex.org/keywords/short-bones","display_name":"short bones","score":0.6970000267028809},{"id":"https://openalex.org/keywords/pulmonary-disease-severity","display_name":"pulmonary disease severity","score":0.7379999756813049},{"id":"https://openalex.org/keywords/nutritional-status","display_name":"nutritional status","score":0.9779999852180481},{"id":"https://openalex.org/keywords/anthropometry","display_name":"anthropometry","score":0.6859999895095825},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8180000185966492},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.4659999907016754}],"concepts":[{"id":"https://openalex.org/C61427482","wikidata":"https://www.wikidata.org/wiki/Q6656244","display_name":"Anthropometry","level":2,"score":0.7227492928504944},{"id":"https://openalex.org/C2778216619","wikidata":"https://www.wikidata.org/wiki/Q185706","display_name":"Wrist","level":2,"score":0.7007222175598145},{"id":"https://openalex.org/C2777695862","wikidata":"https://www.wikidata.org/wiki/Q199507","display_name":"Ulna","level":2,"score":0.6491603851318359},{"id":"https://openalex.org/C2779789666","wikidata":"https://www.wikidata.org/wiki/Q232377","display_name":"Carpal bones","level":3,"score":0.6266627311706543},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6058664321899414},{"id":"https://openalex.org/C89551170","wikidata":"https://www.wikidata.org/wiki/Q1777274","display_name":"Bone age","level":2,"score":0.5671475529670715},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.3703497052192688},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.25307101011276245},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23085355758666992}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1002/ajhb.1310030105","doi":"https://doi.org/10.1002/ajhb.1310030105","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ajhb.1310030105","pdf_url":null,"source":{"id":"https://openalex.org/S179381287","display_name":"American Journal of Human Biology","issn_l":"1042-0533","issn":["1042-0533","1520-6300"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Human Biology","raw_type":"journal-article"},{"id":"pmid:28520312","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28520312","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of human biology : the official journal of the Human Biology Council","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.800000011920929}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W38020331","https://openalex.org/W368475356","https://openalex.org/W579310649","https://openalex.org/W659190622","https://openalex.org/W1496894759","https://openalex.org/W1597884041","https://openalex.org/W1809806071","https://openalex.org/W1878294683","https://openalex.org/W1980967823","https://openalex.org/W1987347023","https://openalex.org/W1999464859","https://openalex.org/W2000727416","https://openalex.org/W2019994559","https://openalex.org/W2020458135","https://openalex.org/W2028568480","https://openalex.org/W2039998838","https://openalex.org/W2046049792","https://openalex.org/W2056246727","https://openalex.org/W2062244559","https://openalex.org/W2070454215","https://openalex.org/W2077447252","https://openalex.org/W2079005528","https://openalex.org/W2094395573","https://openalex.org/W2117594247","https://openalex.org/W2133426090","https://openalex.org/W2150817299","https://openalex.org/W2155149714","https://openalex.org/W2292686439","https://openalex.org/W2402662286","https://openalex.org/W2461162152","https://openalex.org/W2461303257","https://openalex.org/W2578094329","https://openalex.org/W2968043694","https://openalex.org/W2994128225","https://openalex.org/W4244414102","https://openalex.org/W6638240676","https://openalex.org/W7043319585"],"related_works":["https://openalex.org/W38020331","https://openalex.org/W2155149714","https://openalex.org/W1933801646","https://openalex.org/W2030545915","https://openalex.org/W4317569498","https://openalex.org/W2052731068","https://openalex.org/W2039998838","https://openalex.org/W2062609931","https://openalex.org/W2329905851","https://openalex.org/W2134352006"],"abstract_inverted_index":{"Abstract":[0],"From":[1],"a":[2,11,16,33],"sample":[3],"of":[4,18,36,47,78,92,98,168,175,189],"50":[5],"cystic":[6],"fibrosis":[7],"patients":[8],"in":[9,61,106,182],"whom":[10],"previous":[12],"study":[13],"had":[14],"demosntrated":[15],"lack":[17],"statistical":[19],"interdependence":[20,160],"between":[21,87,164],"disease":[22,94,118,170],"severity":[23,119,171],"and":[24,40,68,74,82,101,111,121,151,172,178],"significant":[25,59,129,159],"TW2\u201320":[26],"bone":[27,103,114,132],"age":[28,104,115,133],"delays,":[29,116,134],"hand\u2013wrist":[30,80,191],"radiographs":[31],"for":[32],"preadolescent":[34],"subsample":[35],"30":[37],"(14":[38],"females":[39],"16":[41],"males,":[42],"7.4":[43],"to":[44,55,147],"13.0":[45],"years":[46],"age)":[48],"are":[49,139],"reassessed":[50],"using":[51],"the":[52,66,69,79,85,88,102,184,190],"TW2":[53],"method":[54],"(1)":[56],"elucidate":[57],"any":[58],"differences":[60],"maturational":[62],"delays":[63,105],"exhibited":[64],"by":[65],"carpals":[67,185],"tubular":[70,187],"bones":[71,76,188],"(radius,":[72],"ulna,":[73],"short":[75],"[RUS])":[77],"complex":[81],"(2)":[83],"assess":[84],"relationships":[86,163],"clinically":[89,165],"derived":[90,166],"measure":[91],"pulmonary":[93,117,169],"severity,":[95],"anthropometric":[96,173],"indices":[97],"nutritional":[99,176],"status,":[100],"these":[107],"two":[108],"regions.":[109],"Female":[110],"male":[112],"carpal":[113],"scores,":[120],"weight/height2":[122],"differ":[123],"significantly.":[124],"However,":[125],"both":[126],"sexes":[127],"exhibit":[128],"mean":[130,136],"TW2\u2013carpal":[131],"while":[135],"TW2\u2010RUS":[137],"ages":[138],"either":[140,183],"non\u2010significantly":[141],"delayed":[142,179],"or":[143,161,186],"advanced":[144],"with":[145],"respect":[146],"normative":[148],"standards.":[149],"Correlation":[150],"all\u2010subsets":[152],"multiple":[153],"linear":[154],"regression":[155],"analyses":[156],"reveal":[157],"no":[158],"predictive":[162],"measures":[167,174],"complications":[177],"skeletal":[180],"maturation":[181],"complex.":[192]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}