{"id":"https://openalex.org/W2005612944","doi":"https://doi.org/10.1155/2010/407236","title":"On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study","display_name":"On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2005612944","doi":"https://doi.org/10.1155/2010/407236","mag":"2005612944","pmid":"https://pubmed.ncbi.nlm.nih.gov/21113304","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2990023"},"language":"en","primary_location":{"id":"doi:10.1155/2010/407236","doi":"https://doi.org/10.1155/2010/407236","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2010/407236","pdf_url":"https://downloads.hindawi.com/journals/jo/2010/407236.pdf","source":{"id":"https://openalex.org/S207014961","display_name":"Journal of Oncology","issn_l":"1687-8450","issn":["1687-8450","1687-8469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/jo/2010/407236.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103235703","display_name":"Taoran Li","orcid":"https://orcid.org/0000-0001-7180-4258","observed_orcids":["https://orcid.org/0000-0001-7180-4258"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taoran Li","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaofeng Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaofeng Zhu","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009182686","display_name":"Danthai Thongphiew","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I186335123","display_name":"East Carolina University","ror":"https://ror.org/01vx35703","country_code":"US","type":"education","lineage":["https://openalex.org/I186335123"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danthai Thongphiew","raw_affiliation_strings":["Department of Radiation Oncology, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA","institution_ids":["https://openalex.org/I186335123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042766411","display_name":"William Robert Lee","orcid":"https://orcid.org/0000-0002-3545-0170","observed_orcids":["https://orcid.org/0000-0002-3545-0170"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Robert Lee","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105835357","display_name":"\u017deljko Vuja\u0161kovi\u0107","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zeljko Vujaskovic","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069570157","display_name":"Qiuwen Wu","orcid":"https://orcid.org/0000-0003-0748-7280","observed_orcids":["https://orcid.org/0000-0003-0748-7280"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qiuwen Wu","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Fang-Fang Yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fang-Fang Yin","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":null,"display_name":"Q. Jackie Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Q. Jackie Wu","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":{"value":2550,"currency":"USD","value_usd":2550},"apc_paid":{"value":2550,"currency":"USD","value_usd":2550},"fwci":1.8383,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.83474535,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"2010","issue":null,"first_page":"1","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9599999785423279},{"id":"https://openalex.org/keywords/cone-beam-computed-tomography","display_name":"cone-beam computed tomography","score":0.9580000042915344},{"id":"https://openalex.org/keywords/dose-volume-histograms","display_name":"dose-volume histograms","score":0.8730000257492065},{"id":"https://openalex.org/keywords/dosimetric-quality","display_name":"dosimetric quality","score":0.7289999723434448},{"id":"https://openalex.org/keywords/clinical-implementation","display_name":"clinical implementation","score":0.5789999961853027},{"id":"https://openalex.org/keywords/treatment-planning-system-comparison","display_name":"treatment planning system comparison","score":0.39800000190734863}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8538773059844971},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.6655271053314209},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.6167439818382263},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5345373153686523},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3564388155937195},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.23963332176208496}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1155/2010/407236","doi":"https://doi.org/10.1155/2010/407236","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2010/407236","pdf_url":"https://downloads.hindawi.com/journals/jo/2010/407236.pdf","source":{"id":"https://openalex.org/S207014961","display_name":"Journal of Oncology","issn_l":"1687-8450","issn":["1687-8450","1687-8469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2990023","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2990023","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Oncol","raw_type":"Text"},{"id":"pmid:21113304","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21113304","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of oncology","raw_type":"Journal Article"},{"id":"pmh:oai:TheScholarship.intra.ecu.edu:10342/5741","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10342/5741","pdf_url":null,"source":{"id":"https://openalex.org/S4306402312","display_name":"The Scholarship East Carolina University's Institutional Repository (East Carolina University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I186335123","host_organization_name":"East Carolina University","host_organization_lineage":["https://openalex.org/I186335123"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:969dfb314109423081075ddd00e6ee6b","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/969dfb314109423081075ddd00e6ee6b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Oncology, Vol 2010 (2010)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2010/407236","doi":"https://doi.org/10.1155/2010/407236","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2010/407236","pdf_url":"https://downloads.hindawi.com/journals/jo/2010/407236.pdf","source":{"id":"https://openalex.org/S207014961","display_name":"Journal of Oncology","issn_l":"1687-8450","issn":["1687-8450","1687-8469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.47999998927116394}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309603","display_name":"Varian Medical Systems","ror":"https://ror.org/05yab6874"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005612944.pdf","grobid_xml":"https://content.openalex.org/works/W2005612944.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1874490706","https://openalex.org/W1967172105","https://openalex.org/W1971922011","https://openalex.org/W1976611440","https://openalex.org/W1977179784","https://openalex.org/W1983572063","https://openalex.org/W1992661402","https://openalex.org/W1999329929","https://openalex.org/W2002643006","https://openalex.org/W2004019741","https://openalex.org/W2014106127","https://openalex.org/W2014646029","https://openalex.org/W2024096405","https://openalex.org/W2033581749","https://openalex.org/W2034766072","https://openalex.org/W2039401477","https://openalex.org/W2044224152","https://openalex.org/W2044747677","https://openalex.org/W2045215677","https://openalex.org/W2046716077","https://openalex.org/W2049394478","https://openalex.org/W2050723557","https://openalex.org/W2056538668","https://openalex.org/W2057900848","https://openalex.org/W2083361336","https://openalex.org/W2085320476","https://openalex.org/W2088953052","https://openalex.org/W2111511178","https://openalex.org/W2141232465","https://openalex.org/W2158980875"],"related_works":["https://openalex.org/W7097532915","https://openalex.org/W2024161956","https://openalex.org/W1977594058","https://openalex.org/W2335208167","https://openalex.org/W4389121729","https://openalex.org/W64166593","https://openalex.org/W1970851977","https://openalex.org/W3207869975","https://openalex.org/W2019153754","https://openalex.org/W2095566823"],"abstract_inverted_index":{"The":[0,63],"purpose":[1],"of":[2,14,45,65,104],"this":[3],"paper":[4],"is":[5,56,69,116],"to":[6,71],"evaluate":[7],"the":[8,20,23,72],"feasibility":[9],"and":[10,41,58,87,118,127],"clinical":[11,61,111,121],"dosimetric":[12,125],"benefit":[13],"an":[15,78,91],"on-line,":[16],"that":[17],"is,":[18],"with":[19,60],"patient":[21],"in":[22],"treatment":[24,34,46,84,106],"position,":[25],"Adaptive":[26],"Radiation":[27],"Therapy":[28],"(ART)":[29],"system":[30,86],"for":[31,114,123],"prostate":[32],"cancer":[33],"based":[35,100],"on":[36,101],"daily":[37],"cone-beam":[38],"CT":[39],"imaging":[40],"fast":[42,49],"volumetric":[43],"reoptimization":[44,54],"plans.":[47,107],"A":[48],"intensity-modulated":[50],"radiotherapy":[51],"(IMRT)":[52],"plan":[53],"algorithm":[55],"implemented":[57],"evaluated":[59,89,119],"cases.":[62],"quality":[64],"these":[66],"adapted":[67],"plans":[68,75],"compared":[70],"corresponding":[73],"new":[74],"generated":[76],"by":[77,90],"experienced":[79],"planner":[80],"using":[81,120],"a":[82,102,110],"commercial":[83],"planning":[85],"also":[88],"in-house":[92],"developed":[93],"tool":[94],"estimating":[95],"achievable":[96],"dose-volume":[97],"histograms":[98],"(DVHs)":[99],"database":[103],"existing":[105],"In":[108],"addition,":[109],"implementation":[112],"scheme":[113],"ART":[115],"designed":[117],"cases":[122],"its":[124],"qualities":[126],"efficiency.":[128]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}