{"id":"https://openalex.org/W2005609961","doi":"https://doi.org/10.1159/000098052","title":"Donepezil in Alzheimer\u2019s Disease: What to Expect after 3 Years of Treatment in a Routine Clinical Setting","display_name":"Donepezil in Alzheimer\u2019s Disease: What to Expect after 3 Years of Treatment in a Routine Clinical Setting","publication_year":2006,"publication_date":"2006-12-18","ids":{"openalex":"https://openalex.org/W2005609961","doi":"https://doi.org/10.1159/000098052","mag":"2005609961","pmid":"https://pubmed.ncbi.nlm.nih.gov/17312368"},"language":"en","primary_location":{"id":"doi:10.1159/000098052","doi":"https://doi.org/10.1159/000098052","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000098052","pdf_url":null,"source":{"id":"https://openalex.org/S195598543","display_name":"Dementia and Geriatric Cognitive Disorders","issn_l":"1420-8008","issn":["1420-8008","1421-9824"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dementia and Geriatric Cognitive Disorders","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2005609961"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109306259","display_name":"\u00c5sa K. Wallin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"\u00c5sa K. Wallin","raw_affiliation_strings":["Clinical Memory Research Unit, Department of Clinical Sciences, Malmo, Lund University, Malmo, Sweden. asa.k.wallin@skane.se","Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Memory Research Unit, Department of Clinical Sciences, Malmo, Lund University, Malmo, Sweden. asa.k.wallin@skane.se","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107073671","display_name":"Niels Andreasen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Niels Andreasen","raw_affiliation_strings":["Karolinska Institutet, Alzheimer\u2019s Disease Research Center, Department of Neurotec, Division of Geriatric Medicine, Karolinska University Hospital, Huddinge, Stockholm,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Alzheimer\u2019s Disease Research Center, Department of Neurotec, Division of Geriatric Medicine, Karolinska University Hospital, Huddinge, Stockholm,","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107227319","display_name":"Sture Eriksson","orcid":"https://orcid.org/0000-0002-3098-3787","observed_orcids":["https://orcid.org/0000-0002-3098-3787"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Sture Eriksson","raw_affiliation_strings":["Section of Geriatric Medicine, Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Geriatric Medicine, Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5,","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035663236","display_name":"Stellan B\u00e5tsman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stellan B\u00e5tsman","raw_affiliation_strings":["Department of Primary Care, Kalix V\u00e5rdcentral, Kalix,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Primary Care, Kalix V\u00e5rdcentral, Kalix,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022465358","display_name":"Birgitta N\u00e4sman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Birgitta N\u00e4sman","raw_affiliation_strings":["Section of Geriatric Medicine, Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Geriatric Medicine, Department of Community Medicine and Rehabilitation, Ume\u00e5 University, Ume\u00e5,","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050282332","display_name":"Anne Ekdahl","orcid":"https://orcid.org/0000-0001-8677-176X","observed_orcids":["https://orcid.org/0000-0001-8677-176X"]},"institutions":[{"id":"https://openalex.org/I4210151885","display_name":"Link\u00f6ping University Hospital","ror":"https://ror.org/05h1aye87","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210151885"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anne Ekdahl","raw_affiliation_strings":["Department of Geriatric Medicine University Hospital Link\u00f6ping, Link\u00f6ping,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine University Hospital Link\u00f6ping, Link\u00f6ping,","institution_ids":["https://openalex.org/I4210151885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038197789","display_name":"Lena Kilander","orcid":"https://orcid.org/0000-0001-6600-9110","observed_orcids":["https://orcid.org/0000-0001-6600-9110"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lena Kilander","raw_affiliation_strings":["Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala,","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113560942","display_name":"Mikaela Grut","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802208705","display_name":"Danderyds sjukhus","ror":"https://ror.org/00hm9kt34","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2802208705","https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mikaela Grut","raw_affiliation_strings":["Department of Geriatric Medicine, Cognitive Section Danderyd Hospital, Danderyd,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Cognitive Section Danderyd Hospital, Danderyd,","institution_ids":["https://openalex.org/I2802208705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113659470","display_name":"Marie Ryd\u00e9n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802208705","display_name":"Danderyds sjukhus","ror":"https://ror.org/00hm9kt34","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2802208705","https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Marie Ryd\u00e9n","raw_affiliation_strings":["Department of Geriatric Medicine, Cognitive Section Danderyd Hospital, Danderyd,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Cognitive Section Danderyd Hospital, Danderyd,","institution_ids":["https://openalex.org/I2802208705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107839585","display_name":"Anders Wallin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anders Wallin","raw_affiliation_strings":["Clinical Memory Research Unit, Department of Clinical Sciences, Malmo, Lund University, Malmo, Sweden. asa.k.wallin@skane.se","Institute of Neuroscience, Section of Psychiatry, G\u00f6teborg/Sahlgrenska University Hospital, M\u00f6lndal, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Memory Research Unit, Department of Clinical Sciences, Malmo, Lund University, Malmo, Sweden. asa.k.wallin@skane.se","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Institute of Neuroscience, Section of Psychiatry, G\u00f6teborg/Sahlgrenska University Hospital, M\u00f6lndal, and","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mikael Jonsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mikael Jonsson","raw_affiliation_strings":["Institute of Neuroscience, Section of Psychiatry, G\u00f6teborg/Sahlgrenska University Hospital, M\u00f6lndal, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience, Section of Psychiatry, G\u00f6teborg/Sahlgrenska University Hospital, M\u00f6lndal, and","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018816325","display_name":"Hasse Olofsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125558","display_name":"Uddevalla sjukhus","ror":"https://ror.org/02cs3sv23","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210125558"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Hasse Olofsson","raw_affiliation_strings":["Memory Clinic, Uddevalla Hospital, Uddevalla, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memory Clinic, Uddevalla Hospital, Uddevalla, Sweden","institution_ids":["https://openalex.org/I4210125558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080284808","display_name":"Elisabeth Londos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Elisabeth Londos","raw_affiliation_strings":["Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009234307","display_name":"Carina Wattmo","orcid":"https://orcid.org/0000-0003-4972-0976","observed_orcids":["https://orcid.org/0000-0003-4972-0976"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Carina Wattmo","raw_affiliation_strings":["Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012159562","display_name":"Maria Eriksdotter","orcid":"https://orcid.org/0000-0003-2498-4000","observed_orcids":["https://orcid.org/0000-0003-2498-4000"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Maria Eriksdotter J\u00f6nhagen","raw_affiliation_strings":["Karolinska Institutet, Alzheimer's Disease Research Center, Department of Neurotec, Division of Geriatric Medicine, Karolinska University Hospital, Huddinge, Stockholm,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Alzheimer's Disease Research Center, Department of Neurotec, Division of Geriatric Medicine, Karolinska University Hospital, Huddinge, Stockholm,","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080476940","display_name":"Lennart Minthon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lennart Minthon","raw_affiliation_strings":["Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Memory Research Unit, Department of Clinical Sciences, Malm\u00f6, Lund University, Malm\u00f6,","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.5113,"has_fulltext":false,"cited_by_count":84,"citation_normalized_percentile":{"value":0.94123835,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"23","issue":"3","first_page":"150","last_page":"160"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.047200001776218414,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.04650000110268593,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/donepezil","display_name":"donepezil","score":1.0},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":1.0},{"id":"https://openalex.org/keywords/long-term-treatment","display_name":"long-term treatment","score":0.722000002861023},{"id":"https://openalex.org/keywords/cholinesterase-inhibitors","display_name":"cholinesterase inhibitors","score":0.8500000238418579},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.6769999861717224},{"id":"https://openalex.org/keywords/functional-outcome","display_name":"functional outcome","score":0.527999997138977},{"id":"https://openalex.org/keywords/instrumental-activities-of-daily-living","display_name":"instrumental activities of daily living","score":0.824999988079071},{"id":"https://openalex.org/keywords/real-world-effectiveness","display_name":"real-world effectiveness","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C2780904820","wikidata":"https://www.wikidata.org/wiki/Q415081","display_name":"Donepezil","level":4,"score":0.9600110054016113},{"id":"https://openalex.org/C2780906993","wikidata":"https://www.wikidata.org/wiki/Q5133756","display_name":"Clinical Dementia Rating","level":4,"score":0.6690658926963806},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6316320300102234},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.6108307838439941},{"id":"https://openalex.org/C83849319","wikidata":"https://www.wikidata.org/wiki/Q7295720","display_name":"Rating scale","level":2,"score":0.5042747259140015},{"id":"https://openalex.org/C2779077818","wikidata":"https://www.wikidata.org/wiki/Q913257","display_name":"Mini\u2013Mental State Examination","level":4,"score":0.4906715154647827},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46739158034324646},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4558088481426239},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.454353004693985},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4532119929790497},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44826942682266235},{"id":"https://openalex.org/C79544238","wikidata":"https://www.wikidata.org/wiki/Q423243","display_name":"Activities of daily living","level":2,"score":0.41491204500198364},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.411772757768631},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3015727400779724},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.07180583477020264},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06701534986495972}],"mesh":[{"descriptor_ui":"D000077265","descriptor_name":"Donepezil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007189","descriptor_name":"Indans","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010880","descriptor_name":"Piperidines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018697","descriptor_name":"Nootropic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D018709","descriptor_name":"Statistics, Nonparametric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1159/000098052","doi":"https://doi.org/10.1159/000098052","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000098052","pdf_url":null,"source":{"id":"https://openalex.org/S195598543","display_name":"Dementia and Geriatric Cognitive Disorders","issn_l":"1420-8008","issn":["1420-8008","1421-9824"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dementia and Geriatric Cognitive Disorders","raw_type":"journal-article"},{"id":"pmid:17312368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17312368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dementia and geriatric cognitive disorders","raw_type":"Clinical Trial"},{"id":"pmh:oai:lup.lub.lu.se:7df2d824-6d5c-4886-9506-30d3f296e5e0","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/165526","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1420-8008","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W84377585","https://openalex.org/W180469417","https://openalex.org/W261910342","https://openalex.org/W1164896577","https://openalex.org/W1472735294","https://openalex.org/W1498917275","https://openalex.org/W1504356022","https://openalex.org/W1847168837","https://openalex.org/W1895538680","https://openalex.org/W1953027527","https://openalex.org/W1972294144","https://openalex.org/W1977048491","https://openalex.org/W1987985059","https://openalex.org/W1997886955","https://openalex.org/W2004713321","https://openalex.org/W2009329257","https://openalex.org/W2014091144","https://openalex.org/W2016293441","https://openalex.org/W2034963833","https://openalex.org/W2036228747","https://openalex.org/W2039089562","https://openalex.org/W2040836716","https://openalex.org/W2053254879","https://openalex.org/W2056034609","https://openalex.org/W2059094083","https://openalex.org/W2059718578","https://openalex.org/W2060575765","https://openalex.org/W2064649894","https://openalex.org/W2072249708","https://openalex.org/W2080291833","https://openalex.org/W2081482233","https://openalex.org/W2101265858","https://openalex.org/W2107061279","https://openalex.org/W2125332642","https://openalex.org/W2128529067","https://openalex.org/W2132316334","https://openalex.org/W2137103253","https://openalex.org/W2140291226","https://openalex.org/W2156220037","https://openalex.org/W2168891350","https://openalex.org/W2415652464","https://openalex.org/W2474469682","https://openalex.org/W4233035841","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W183757201","https://openalex.org/W1786578036","https://openalex.org/W2072819609","https://openalex.org/W2018309238","https://openalex.org/W2076010991","https://openalex.org/W2081285591","https://openalex.org/W2016958718","https://openalex.org/W2746912932","https://openalex.org/W2014091144","https://openalex.org/W2064649894"],"abstract_inverted_index":{"BACKGROUND/AIMS:":[0],"Clinical":[1],"short-term":[2],"trails":[3],"have":[4],"shown":[5],"positive":[6,106,200],"effects":[7],"of":[8,18,54,81,95,115,123,178,183],"donepezil":[9,196],"treatment":[10,21,58,124,197],"in":[11,22,113,130,153,190,205],"patients":[12,116,180],"with":[13,50,59,64,176],"Alzheimer's":[14,55,69],"disease.":[15],"The":[16,32,99],"outcome":[17,204],"continuous":[19],"long-term":[20],"the":[23,51,125,139,160,165,179,184,191,206],"routine":[24,207],"clinical":[25,52,208],"settings":[26],"remains":[27],"to":[28],"be":[29],"investigated.":[30],"METHODS:":[31],"Swedish":[33],"Alzheimer":[34],"Treatment":[35],"Study":[36],"(SATS)":[37],"is":[38,149],"a":[39,92,199],"descriptive,":[40],"prospective,":[41],"longitudinal,":[42],"multicentre":[43],"study.":[44],"Four":[45],"hundred":[46],"and":[47,78,87,112,138,157,202],"thirty-five":[48],"outpatients":[49],"diagnosis":[53],"disease,":[56],"received":[57],"donepezil.":[60],"Patients":[61],"were":[62,186],"assessed":[63],"Mini-Mental":[65],"State":[66],"Examination":[67],"(MMSE),":[68],"Disease":[70],"Assessment":[71],"Scale-cognitive":[72],"subscale":[73],"(ADAS-cog),":[74],"global":[75,192,201],"rating":[76],"(CIBIC)":[77],"Instrumental":[79],"Activities":[80],"Daily":[82],"Living":[83],"(IADL)":[84],"at":[85],"baseline":[86,104,129],"every":[88],"6":[89,110],"months":[90,111],"for":[91,107,117],"total":[93],"period":[94],"3":[96,121,174],"years.":[97],"RESULTS:":[98],"mean":[100,126],"MMSE":[101],"change":[102,127],"from":[103,128],"was":[105,132,142],"more":[108],"than":[109,151,159],"subgroups":[114],"12":[118],"months.":[119],"After":[120,173],"years":[122,175],"MMSE-score":[131],"3.8":[133],"points":[134,144],"(95%":[135,145],"CI,":[136,146,171],"3.0-4.7)":[137],"ADAS-cog":[140,161],"rise":[141,162],"8.2":[143],"6.4-10.1).":[147],"This":[148],"better":[150,158],"expected":[152],"untreated":[154],"historical":[155],"cohorts,":[156],"calculated":[163],"by":[164],"Stern":[166],"equation":[167],"(15.6":[168],"points;":[169],"95%":[170],"14.5-16.6).":[172],"38%":[177],"remaining,":[181],"30%":[182],"them":[185],"unchanged":[187],"or":[188],"improved":[189],"assessment.":[193],"CONCLUSION:":[194],"Three-year":[195],"showed":[198],"cognitive":[203],"setting.":[209]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}