{"id":"https://openalex.org/W2005609770","doi":"https://doi.org/10.1001/archderm.139.4.475","title":"Cutaneous Involvement in Multiple Myeloma","display_name":"Cutaneous Involvement in Multiple Myeloma","publication_year":2003,"publication_date":"2003-04-01","ids":{"openalex":"https://openalex.org/W2005609770","doi":"https://doi.org/10.1001/archderm.139.4.475","mag":"2005609770","pmid":"https://pubmed.ncbi.nlm.nih.gov/12707095"},"language":"en","primary_location":{"id":"doi:10.1001/archderm.139.4.475","doi":"https://doi.org/10.1001/archderm.139.4.475","is_oa":true,"landing_page_url":"https://doi.org/10.1001/archderm.139.4.475","pdf_url":"https://jamanetwork.com/journals/jamadermatology/articlepdf/479282/dst20171.pdf","source":{"id":"https://openalex.org/S115046667","display_name":"Archives of Dermatology","issn_l":"0003-987X","issn":["0003-987X","1538-3652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://jamanetwork.com/journals/jamadermatology/articlepdf/479282/dst20171.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016746558","display_name":"Lu\u00eds Requena","orcid":"https://orcid.org/0000-0002-1347-3507","observed_orcids":["https://orcid.org/0000-0002-1347-3507"]},"institutions":[{"id":"https://openalex.org/I4210129357","display_name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/049nvyb15","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210129357"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Luis Requena","raw_affiliation_strings":["Department of Dermatology, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Universidad Aut\u00f3noma, Madrid, Spain. lrequena@fjd.es"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Universidad Aut\u00f3noma, Madrid, Spain. lrequena@fjd.es","institution_ids":["https://openalex.org/I4210129357","https://openalex.org/I63634437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082098822","display_name":"Heinz Kutzner","orcid":"https://orcid.org/0000-0001-6248-3050","observed_orcids":["https://orcid.org/0000-0001-6248-3050"]},"institutions":[{"id":"https://openalex.org/I4210129357","display_name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/049nvyb15","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210129357"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Heinz Kutzner","raw_affiliation_strings":["Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain","institution_ids":["https://openalex.org/I4210129357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112088452","display_name":"Gabriele Palmedo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129357","display_name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/049nvyb15","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210129357"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Gabriele Palmedo","raw_affiliation_strings":["Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain","institution_ids":["https://openalex.org/I4210129357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080370646","display_name":"Eduardo J. Calonje","orcid":"https://orcid.org/0000-0001-7475-6423","observed_orcids":["https://orcid.org/0000-0001-7475-6423"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eduardo Calonje","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074491220","display_name":"Celia Requena","orcid":"https://orcid.org/0000-0001-9977-4169","observed_orcids":["https://orcid.org/0000-0001-9977-4169"]},"institutions":[{"id":"https://openalex.org/I4210129357","display_name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/049nvyb15","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210129357"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Celia Requena","raw_affiliation_strings":["Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain","institution_ids":["https://openalex.org/I4210129357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048844071","display_name":"G. A. Castro Perez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gemma P\u00e9rez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100874088","display_name":"Mar\u00eda Antonia Pastor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mar\u00eda Antonia Pastor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5052362224","display_name":"Omar Pastor Sang\u00fceza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129357","display_name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/049nvyb15","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210129357"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Omar P. Sangueza","raw_affiliation_strings":["Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology , Fundacio \u00b4n Jime \u00b4nez D\u0131 \u00b4az , Avda Reyes Cato \u00b4licos 2 , 28040- Madrid , Spain","institution_ids":["https://openalex.org/I4210129357"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5016746558"],"corresponding_institution_ids":["https://openalex.org/I4210129357","https://openalex.org/I63634437"],"apc_list":null,"apc_paid":null,"fwci":2.3882,"has_fulltext":true,"cited_by_count":126,"citation_normalized_percentile":{"value":0.8841012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"139","issue":"4","first_page":"475","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12433","display_name":"Skin Diseases and Diabetes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/skin-involvement","display_name":"skin involvement","score":0.8899999856948853},{"id":"https://openalex.org/keywords/cutaneous-metastasis","display_name":"cutaneous metastasis","score":0.8889999985694885},{"id":"https://openalex.org/keywords/immunoglobulin-classes","display_name":"immunoglobulin classes","score":0.7390000224113464},{"id":"https://openalex.org/keywords/iga-lambda","display_name":"IgA lambda","score":0.8040000200271606},{"id":"https://openalex.org/keywords/igg-kappa","display_name":"IgG kappa","score":0.7689999938011169},{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-gene-rearrangement","display_name":"immunoglobulin heavy chain gene rearrangement","score":0.800000011920929},{"id":"https://openalex.org/keywords/cd79a","display_name":"CD79a","score":0.7599999904632568},{"id":"https://openalex.org/keywords/syndecan-1","display_name":"syndecan-1","score":0.9599999785423279},{"id":"https://openalex.org/keywords/epithelial-membrane-antigen","display_name":"epithelial membrane antigen","score":0.7329999804496765},{"id":"https://openalex.org/keywords/survival-after-metastasis","display_name":"survival after metastasis","score":0.5540000200271606},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8101279735565186},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.753929078578949},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.6059028506278992},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5917273759841919},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5768718719482422},{"id":"https://openalex.org/C2778964538","wikidata":"https://www.wikidata.org/wiki/Q2090167","display_name":"Plasmacytoma","level":3,"score":0.4884161353111267},{"id":"https://openalex.org/C36394416","wikidata":"https://www.wikidata.org/wiki/Q949267","display_name":"Immunoglobulin light chain","level":3,"score":0.4770316779613495},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.46933168172836304},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.43778854608535767},{"id":"https://openalex.org/C2780439664","wikidata":"https://www.wikidata.org/wiki/Q7535376","display_name":"Skin biopsy","level":3,"score":0.432394802570343},{"id":"https://openalex.org/C2776396001","wikidata":"https://www.wikidata.org/wiki/Q250694","display_name":"Plasma cell","level":3,"score":0.4304999113082886},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.20635607838630676},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0918627679347992},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.08141869306564331}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010950","descriptor_name":"Plasma Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016161","descriptor_name":"Genes, Retinoblastoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1001/archderm.139.4.475","doi":"https://doi.org/10.1001/archderm.139.4.475","is_oa":true,"landing_page_url":"https://doi.org/10.1001/archderm.139.4.475","pdf_url":"https://jamanetwork.com/journals/jamadermatology/articlepdf/479282/dst20171.pdf","source":{"id":"https://openalex.org/S115046667","display_name":"Archives of Dermatology","issn_l":"0003-987X","issn":["0003-987X","1538-3652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Dermatology","raw_type":"journal-article"},{"id":"pmid:12707095","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12707095","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of dermatology","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1001/archderm.139.4.475","doi":"https://doi.org/10.1001/archderm.139.4.475","is_oa":true,"landing_page_url":"https://doi.org/10.1001/archderm.139.4.475","pdf_url":"https://jamanetwork.com/journals/jamadermatology/articlepdf/479282/dst20171.pdf","source":{"id":"https://openalex.org/S115046667","display_name":"Archives of Dermatology","issn_l":"0003-987X","issn":["0003-987X","1538-3652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Dermatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005609770.pdf","grobid_xml":"https://content.openalex.org/works/W2005609770.grobid-xml"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W120917320","https://openalex.org/W155886465","https://openalex.org/W178760906","https://openalex.org/W1887989049","https://openalex.org/W1918030391","https://openalex.org/W1944291718","https://openalex.org/W1967394169","https://openalex.org/W1967853236","https://openalex.org/W1968136838","https://openalex.org/W1968588231","https://openalex.org/W1969913544","https://openalex.org/W1975277762","https://openalex.org/W1978240928","https://openalex.org/W1981748837","https://openalex.org/W1981776745","https://openalex.org/W1984743916","https://openalex.org/W1987849320","https://openalex.org/W1997866272","https://openalex.org/W2005053283","https://openalex.org/W2006818745","https://openalex.org/W2008584223","https://openalex.org/W2009989031","https://openalex.org/W2010408983","https://openalex.org/W2015623629","https://openalex.org/W2016214584","https://openalex.org/W2030697294","https://openalex.org/W2030798666","https://openalex.org/W2031640614","https://openalex.org/W2034372638","https://openalex.org/W2035860033","https://openalex.org/W2038616114","https://openalex.org/W2038618406","https://openalex.org/W2046492465","https://openalex.org/W2046522417","https://openalex.org/W2049305777","https://openalex.org/W2049362047","https://openalex.org/W2050962199","https://openalex.org/W2054848279","https://openalex.org/W2062443823","https://openalex.org/W2063864922","https://openalex.org/W2065914548","https://openalex.org/W2066823488","https://openalex.org/W2070562500","https://openalex.org/W2078122127","https://openalex.org/W2079683197","https://openalex.org/W2079694822","https://openalex.org/W2083437862","https://openalex.org/W2086500181","https://openalex.org/W2090179653","https://openalex.org/W2096428903","https://openalex.org/W2096746091","https://openalex.org/W2097239715","https://openalex.org/W2108649834","https://openalex.org/W2114871582","https://openalex.org/W2126816720","https://openalex.org/W2276983539","https://openalex.org/W2314302845","https://openalex.org/W2324313730","https://openalex.org/W2335487653","https://openalex.org/W2398650528","https://openalex.org/W2402886785","https://openalex.org/W2414191389","https://openalex.org/W2414400212","https://openalex.org/W2419153674","https://openalex.org/W2482857886","https://openalex.org/W2590376626","https://openalex.org/W2944066305","https://openalex.org/W4232537386","https://openalex.org/W4239235006","https://openalex.org/W4244372215","https://openalex.org/W6662062192"],"related_works":["https://openalex.org/W2252678253","https://openalex.org/W2038616114","https://openalex.org/W2031640614","https://openalex.org/W3157329241","https://openalex.org/W4294751670","https://openalex.org/W7166145842","https://openalex.org/W7167058275","https://openalex.org/W2406995862","https://openalex.org/W2026669949","https://openalex.org/W2119821780"],"abstract_inverted_index":{"BACKGROUND:":[0],"Specific":[1],"cutaneous":[2,34,65,109,151,312,338,360,371],"involvement":[3,35],"in":[4,16,56,94,189,249,301,305],"patients":[5,32,61,146,329,394],"with":[6,33,62,97,147,167,364,395],"multiple":[7,160],"myeloma":[8],"(MM)":[9],"is":[10],"very":[11],"uncommon.":[12],"It":[13],"usually":[14],"occurs":[15],"late":[17],"stages":[18],"of":[19,24,36,60,77,80,120,131,159,239,252,319,337,349,375,393],"MM":[20,37,63,148,365],"as":[21,111,113,246],"a":[22,104,168,194,198,331,346,367,390],"reflection":[23],"increased":[25],"tumor":[26],"cell":[27],"burden.":[28],"We":[29,52],"studied":[30],"8":[31,145,293,328],"without":[38],"underlying":[39],"bony":[40],"lesions":[41,152,157],"and":[42,64,73,90,108,117,135,141,149,179,188,217,221,226,234,265,275,294,351,358],"reviewed":[43],"the":[44,57,74,88,91,114,121,126,202,231,235,240,244,250,253,288,311,317,320,335,355,359,376,380],"literature":[45],"on":[46,99],"this":[47],"rare":[48],"dermatologic":[49],"manifestation.":[50],"DESIGN:":[51],"were":[53,71,153,176,211,243,257,262],"particularly":[54],"interested":[55],"clinical":[58],"course":[59],"metastases,":[66],"including":[67],"survival":[68,369],"once":[69,370],"metastases":[70,372],"detected":[72],"possible":[75,101],"influence":[76],"various":[78],"forms":[79],"therapy.":[81,377],"Our":[82],"goal":[83],"was":[84,268,345],"also":[85],"to":[86,201,388],"identify":[87,389],"immunoglobulin":[89,106,232,350],"light-chain":[92,236,352],"type":[93,237,353],"these":[95,306],"cases,":[96],"emphasis":[98],"any":[100],"association":[102],"between":[103,354],"particular":[105],"class":[107],"involvement,":[110],"well":[112],"histopathologic,":[115],"immunohistochemical,":[116],"cytogenetic":[118],"features":[119],"neoplastic":[122,208,241,313],"plasma":[123,183,209,314,361],"cells":[124,184,210,242,315],"involving":[125],"skin.":[127],"SETTING:":[128],"University":[129],"department":[130],"dermatology,":[132],"university":[133],"hospital,":[134],"private":[136],"practice.":[137],"PATIENTS:":[138],"Medical":[139],"records":[140],"biopsy":[142],"specimens":[143],"from":[144],"specific":[150],"reviewed.":[154],"RESULTS:":[155],"Cutaneous":[156],"consisted":[158],"erythematous":[161],"or":[162,165],"violaceous":[163],"nodules":[164],"plaques":[166],"wide":[169],"anatomical":[170],"distribution.":[171],"Histopathologically,":[172],"2":[173,260],"different":[174],"patterns":[175],"identified:":[177],"nodular":[178],"diffuse":[180],"interstitial.":[181],"Neoplastic":[182],"showed":[185,316,366],"atypical":[186],"features,":[187],"1":[190,266],"case":[191,230,267],"they":[192],"displayed":[193],"spindle":[195],"shape,":[196],"giving":[197],"sarcomatoid":[199],"appearance":[200],"lesion.":[203],"Immunohistochemical":[204],"studies":[205],"demonstrated":[206,309],"that":[207,310],"strongly":[212],"positive":[213,223],"for":[214,224,284,290],"CD79a,":[215],"CD138,":[216],"epithelial":[218],"membrane":[219],"antigen,":[220],"variably":[222],"VS38c":[225],"CD43.":[227],"In":[228,271,341],"each":[229],"profile":[233],"expression":[238],"same":[245],"those":[247],"identified":[248],"serum":[251,356],"patients:":[254],"5":[255],"cases":[256,261,272,308],"IgA":[258,269],"lambda;":[259],"IgG":[263],"kappa;":[264],"kappa.":[270],"2,":[273],"3,":[274],"4,":[276],"polymerase":[277],"chain":[278],"reaction":[279],"investigations":[280,289,304],"revealed":[281],"monoclonal":[282],"rearrangement":[283],"IgH":[285],"genes,":[286],"whereas":[287],"human":[291],"herpesvirus":[292],"Epstein-Barr":[295],"virus":[296],"yielded":[297],"negative":[298],"results.":[299],"Fluorescent":[300],"situ":[302],"hybridization":[303],"3":[307],"deletion":[318,379],"rb-1":[321,381],"(retinoblastoma)":[322],"gene.":[323],"Despite":[324],"aggressive":[325],"chemotherapy,":[326],"all":[327],"died":[330],"few":[332],"months":[333],"after":[334],"development":[336],"involvement.":[339],"CONCLUSIONS:":[340],"our":[342],"series,":[343],"there":[344],"perfect":[347],"correlation":[348],"electrophoresis":[357],"cells.":[362],"Patients":[363],"short":[368],"appeared":[373],"independently":[374],"The":[378],"gene":[382],"may":[383],"provide":[384],"prognostically":[385],"relevant":[386],"information":[387],"high-risk":[391],"subset":[392],"MM.":[396]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}