{"id":"https://openalex.org/W2005494868","doi":"https://doi.org/10.1089/lps.1991.1.241","title":"Prospective Analysis of Cardiopulmonary Responses to Laparoscopic Cholecystectomy","display_name":"Prospective Analysis of Cardiopulmonary Responses to Laparoscopic Cholecystectomy","publication_year":1991,"publication_date":"1991-10-01","ids":{"openalex":"https://openalex.org/W2005494868","doi":"https://doi.org/10.1089/lps.1991.1.241","mag":"2005494868","pmid":"https://pubmed.ncbi.nlm.nih.gov/1834277"},"language":"en","primary_location":{"id":"doi:10.1089/lps.1991.1.241","doi":"https://doi.org/10.1089/lps.1991.1.241","is_oa":false,"landing_page_url":"https://doi.org/10.1089/lps.1991.1.241","pdf_url":null,"source":{"id":"https://openalex.org/S2764908273","display_name":"Journal of Laparoendoscopic Surgery","issn_l":"1052-3901","issn":["1052-3901","2332-502X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Laparoendoscopic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069575378","display_name":"Se-Yuan Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"SE-YUAN LIU","raw_affiliation_strings":["Department of Surgery, Harbor-UCLA Medical Center, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Harbor-UCLA Medical Center, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765","https://openalex.org/I4210165985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081384221","display_name":"THOMAS A. LEIGHTON","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"THOMAS LEIGHTON","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064732405","display_name":"Ian D. Davis","orcid":"https://orcid.org/0000-0002-9066-8244","observed_orcids":["https://orcid.org/0000-0002-9066-8244"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"IAN DAVIS","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107429229","display_name":"Stanley R. Klein","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"STANLEY KLEIN","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103483405","display_name":"Maurice Lippmann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MAURICE LIPPMANN","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005051305","display_name":"Fred S. Bongard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"FRED BONGARD","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":15.0598,"has_fulltext":false,"cited_by_count":149,"citation_normalized_percentile":{"value":0.99246658,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"1","issue":"5","first_page":"241","last_page":"246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12333","display_name":"Abdominal Surgery and Complications","score":0.4047999978065491,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12333","display_name":"Abdominal Surgery and Complications","score":0.4047999978065491,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.21950000524520874,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12053","display_name":"Minimally Invasive Surgical Techniques","score":0.08889999985694885,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laparoscopic-cholecystectomy","display_name":"laparoscopic cholecystectomy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/co2-insufflation","display_name":"carbon dioxide insufflation","score":0.9559999704360962},{"id":"https://openalex.org/keywords/hypercapnia","display_name":"hypercapnia","score":0.9160000085830688},{"id":"https://openalex.org/keywords/respiratory-acidosis","display_name":"respiratory acidosis","score":0.9729999899864197},{"id":"https://openalex.org/keywords/end-tidal-carbon-dioxide","display_name":"end-tidal carbon dioxide","score":0.781000018119812},{"id":"https://openalex.org/keywords/arterial-co2","display_name":"arterial carbon dioxide","score":0.8209999799728394},{"id":"https://openalex.org/keywords/capnography","display_name":"capnography","score":0.7749999761581421},{"id":"https://openalex.org/keywords/minute-ventilation","display_name":"minute ventilation","score":0.6349999904632568},{"id":"https://openalex.org/keywords/blood-pressure-response","display_name":"blood pressure response","score":0.7289999723434448},{"id":"https://openalex.org/keywords/cardiovascular-effects","display_name":"cardiovascular effects","score":0.38499999046325684},{"id":"https://openalex.org/keywords/arterial-blood-gas","display_name":"arterial blood gases","score":0.5170000195503235},{"id":"https://openalex.org/keywords/anesthesia-monitoring","display_name":"anesthesia monitoring","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9369247555732727},{"id":"https://openalex.org/C2909479059","wikidata":"https://www.wikidata.org/wiki/Q615759","display_name":"Hypercarbia","level":3,"score":0.8530985713005066},{"id":"https://openalex.org/C2778207410","wikidata":"https://www.wikidata.org/wiki/Q1728669","display_name":"Capnography","level":2,"score":0.7788113355636597},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.7315335869789124},{"id":"https://openalex.org/C2781382112","wikidata":"https://www.wikidata.org/wiki/Q7053142","display_name":"Normocapnia","level":4,"score":0.6078170537948608},{"id":"https://openalex.org/C2776892627","wikidata":"https://www.wikidata.org/wiki/Q6042053","display_name":"Insufflation","level":2,"score":0.5881431698799133},{"id":"https://openalex.org/C2779594553","wikidata":"https://www.wikidata.org/wiki/Q1641494","display_name":"Hypoventilation","level":3,"score":0.5794601440429688},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5368587970733643},{"id":"https://openalex.org/C2777037550","wikidata":"https://www.wikidata.org/wiki/Q615759","display_name":"Hypercapnia","level":3,"score":0.5092459917068481},{"id":"https://openalex.org/C2779537118","wikidata":"https://www.wikidata.org/wiki/Q618362","display_name":"Arterial blood","level":2,"score":0.49477285146713257},{"id":"https://openalex.org/C2778553927","wikidata":"https://www.wikidata.org/wiki/Q185089","display_name":"Acidosis","level":2,"score":0.4465548098087311},{"id":"https://openalex.org/C2776989520","wikidata":"https://www.wikidata.org/wiki/Q2145935","display_name":"Respiratory acidosis","level":3,"score":0.4405675232410431},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.43462345004081726},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.4302847981452942},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.18736955523490906},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17899861931800842},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000142","descriptor_name":"Acidosis, Respiratory","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000142","descriptor_name":"Acidosis, Respiratory","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000142","descriptor_name":"Acidosis, Respiratory","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002763","descriptor_name":"Cholecystectomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002763","descriptor_name":"Cholecystectomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002763","descriptor_name":"Cholecystectomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007327","descriptor_name":"Insufflation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007327","descriptor_name":"Insufflation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007327","descriptor_name":"Insufflation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010535","descriptor_name":"Laparoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010535","descriptor_name":"Laparoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010535","descriptor_name":"Laparoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011028","descriptor_name":"Pneumoperitoneum, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011028","descriptor_name":"Pneumoperitoneum, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011028","descriptor_name":"Pneumoperitoneum, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013990","descriptor_name":"Tidal Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013990","descriptor_name":"Tidal Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013990","descriptor_name":"Tidal Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/lps.1991.1.241","doi":"https://doi.org/10.1089/lps.1991.1.241","is_oa":false,"landing_page_url":"https://doi.org/10.1089/lps.1991.1.241","pdf_url":null,"source":{"id":"https://openalex.org/S2764908273","display_name":"Journal of Laparoendoscopic Surgery","issn_l":"1052-3901","issn":["1052-3901","2332-502X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Laparoendoscopic Surgery","raw_type":"journal-article"},{"id":"pmid:1834277","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1834277","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of laparoendoscopic surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation","score":0.550000011920929}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1968936653","https://openalex.org/W1984050611","https://openalex.org/W2003217516","https://openalex.org/W2018449095","https://openalex.org/W2019544556","https://openalex.org/W2026209251","https://openalex.org/W2041521271","https://openalex.org/W2049611464","https://openalex.org/W2158700987","https://openalex.org/W2166044292","https://openalex.org/W2171209638","https://openalex.org/W3105093708","https://openalex.org/W4236160928"],"related_works":["https://openalex.org/W2906672923","https://openalex.org/W1965673455","https://openalex.org/W200942747","https://openalex.org/W2460616978","https://openalex.org/W2170784621","https://openalex.org/W2029087097","https://openalex.org/W2064877547","https://openalex.org/W2130636710","https://openalex.org/W2011607227","https://openalex.org/W116630096"],"abstract_inverted_index":{"This":[0,180],"prospective":[1],"study":[2],"evaluates":[3],"the":[4,10,58,127,130,150,173,185],"extent":[5],"and":[6,46,62,76,100,115,195,208,218],"temporal":[7],"course":[8,128],"of":[9,13,57,129,149,221],"cardiorespiratory":[11],"effects":[12],"CO2":[14,61,102],"during":[15,126],"laparoscopic":[16],"cholecystectomy":[17,199],"in":[18,212,224],"otherwise":[19,213],"healthy":[20,214],"patients.":[21,215],"Sixteen":[22],"patients":[23,152,225],"(M:F":[24],"=":[25,29],"3:13,":[26],"average":[27],"age":[28],"40.2":[30],"+/-":[31,70,107,112,117,122,137,141,168,177],"14.1":[32],"years)":[33],"were":[34,52,74],"monitored":[35],"with":[36,60,184,200,226],"capnography,":[37],"transesophageal":[38],"cardiac":[39],"output,":[40],"continuous":[41],"blood":[42,50],"pressure,":[43],"heart":[44],"rate,":[45],"pulse":[47],"oximetry.":[48],"Arterial":[49,132],"gases":[51],"obtained":[53],"immediately":[54],"before":[55,63],"insufflation":[56,203],"abdomen":[59],"desufflation.":[64],"Average":[65],"operative":[66],"time":[67],"was":[68,81,182,190],"137":[69],"13":[71],"minutes.":[72],"Patients":[73],"paralyzed":[75],"mechanically":[77],"ventilated.":[78],"Minute":[79],"ventilation":[80,156],"increased":[82,104,154,165],"if":[83],"EtCO2":[84,194],"exceeded":[85],"45":[86],"mmHg":[87,94,109,114,119,170],"or":[88],"rose":[89],"by":[90,161],"more":[91],"than":[92],"12":[93],"from":[95,105,135,166],"baseline.":[96],"End":[97],"tidal":[98],"(EtCO2)":[99],"arterial":[101],"(PaCO2)":[103],"31.4":[106],"0.7":[108,118],"to":[110,120,139,158,175,233],"42.1":[111],"1.6":[113],"33.3":[116],"43.7":[121],"1.2":[123],"mmHg,":[124],"respectively,":[125],"procedure.":[131],"pH":[133],"decreased":[134],"7.43":[136],"0.01":[138],"7.34":[140],"0.01,":[142],"while":[143],"bicarbonate":[144],"concentration":[145],"remained":[146],"unchanged.":[147],"Thirteen":[148],"16":[151],"required":[153,232],"minute":[155],"due":[157],"hypercarbia":[159],"detected":[160],"capnography.":[162],"Blood":[163],"pressure":[164],"78":[167],"2":[169,178],"(mean)":[171],"at":[172],"start":[174],"98":[176],"mmHg.":[179],"increase":[181],"coincidental":[183],"maximal":[186],"PaCO2.":[187],"Good":[188],"agreement":[189],"observed":[191],"between":[192],"paired":[193],"PaCO2":[196],"measurements.":[197],"Laparoscopic":[198],"carbon":[201],"dioxide":[202],"causes":[204],"significant":[205],"respiratory":[206],"acidosis":[207],"associated":[209],"cardiovascular":[210],"changes":[211],"Careful":[216],"monitoring":[217],"cautious":[219],"application":[220],"this":[222],"technique":[223],"pre-existing":[227],"cardiopulmonary":[228],"disorders":[229],"will":[230],"be":[231],"prevent":[234],"acute":[235],"decompensation.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}