{"id":"https://openalex.org/W2005485506","doi":"https://doi.org/10.1016/j.bbagrm.2014.05.021","title":"Bile acid signaling and liver regeneration","display_name":"Bile acid signaling and liver regeneration","publication_year":2014,"publication_date":"2014-05-27","ids":{"openalex":"https://openalex.org/W2005485506","doi":"https://doi.org/10.1016/j.bbagrm.2014.05.021","mag":"2005485506","pmid":"https://pubmed.ncbi.nlm.nih.gov/24878541"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbagrm.2014.05.021","doi":"https://doi.org/10.1016/j.bbagrm.2014.05.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbagrm.2014.05.021","pdf_url":null,"source":{"id":"https://openalex.org/S4210203689","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","issn_l":"1874-9399","issn":["1874-9399","1876-4320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246016","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039848197","display_name":"Mingjie Fan","orcid":"https://orcid.org/0000-0002-2930-9998","observed_orcids":["https://orcid.org/0000-0002-2930-9998"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingjie Fan","raw_affiliation_strings":["Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066933299","display_name":"Xichun Wang","orcid":"https://orcid.org/0000-0001-5096-3970","observed_orcids":["https://orcid.org/0000-0001-5096-3970"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4387156432","display_name":"Beckman Research Institute","ror":"https://ror.org/05fazth07","country_code":null,"type":"facility","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xichun Wang","raw_affiliation_strings":["Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085200442","display_name":"Ganyu Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4387156432","display_name":"Beckman Research Institute","ror":"https://ror.org/05fazth07","country_code":null,"type":"facility","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ganyu Xu","raw_affiliation_strings":["Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013814632","display_name":"Qingfeng Yan","orcid":"https://orcid.org/0000-0002-5381-8426","observed_orcids":["https://orcid.org/0000-0002-5381-8426"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingfeng Yan","raw_affiliation_strings":["Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071384941","display_name":"Wendong Huang","orcid":"https://orcid.org/0000-0003-3735-9466","observed_orcids":["https://orcid.org/0000-0003-3735-9466"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4387156432","display_name":"Beckman Research Institute","ror":"https://ror.org/05fazth07","country_code":null,"type":"facility","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Wendong Huang","raw_affiliation_strings":["Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China; Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA. Electronic address: whuang@coh.org","Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA","Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China; Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA. Electronic address: whuang@coh.org","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432","https://openalex.org/I76130692"]},{"raw_affiliation_string":"Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]},{"raw_affiliation_string":"Institute of Genetics, College of Life Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071384941"],"corresponding_institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432","https://openalex.org/I76130692"],"apc_list":{"value":3840,"currency":"USD","value_usd":3840},"apc_paid":null,"fwci":6.3939,"has_fulltext":false,"cited_by_count":109,"citation_normalized_percentile":{"value":0.97599006,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"1849","issue":"2","first_page":"196","last_page":"200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.016200000420212746,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bile-acids","display_name":"bile acids","score":0.8090000152587891},{"id":"https://openalex.org/keywords/liver-regeneration","display_name":"liver regeneration","score":0.9539999961853027},{"id":"https://openalex.org/keywords/farnesoid-x-receptor","display_name":"farnesoid X receptor","score":0.9020000100135803},{"id":"https://openalex.org/keywords/tgr5","display_name":"TGR5","score":0.902999997138977},{"id":"https://openalex.org/keywords/partial-hepatectomy","display_name":"partial hepatectomy","score":0.9309999942779541},{"id":"https://openalex.org/keywords/liver-injury","display_name":"liver injury","score":0.9419999718666077},{"id":"https://openalex.org/keywords/nuclear-receptors","display_name":"nuclear receptors","score":0.8510000109672546},{"id":"https://openalex.org/keywords/bile-acid-excretion","display_name":"bile acid excretion","score":0.7229999899864197},{"id":"https://openalex.org/keywords/bile-acid-signaling","display_name":"bile acid signaling","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C203862802","wikidata":"https://www.wikidata.org/wiki/Q14905041","display_name":"Farnesoid X receptor","level":5,"score":0.9295878410339355},{"id":"https://openalex.org/C2776795407","wikidata":"https://www.wikidata.org/wiki/Q19597761","display_name":"Liver regeneration","level":3,"score":0.8606762886047363},{"id":"https://openalex.org/C39321552","wikidata":"https://www.wikidata.org/wiki/Q18052005","display_name":"G protein-coupled bile acid receptor","level":3,"score":0.7668886780738831},{"id":"https://openalex.org/C2779399885","wikidata":"https://www.wikidata.org/wiki/Q413288","display_name":"Bile acid","level":2,"score":0.6928327679634094},{"id":"https://openalex.org/C63932345","wikidata":"https://www.wikidata.org/wiki/Q422500","display_name":"Nuclear receptor","level":4,"score":0.5966904163360596},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5886335372924805},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5268839001655579},{"id":"https://openalex.org/C2776909242","wikidata":"https://www.wikidata.org/wiki/Q1514021","display_name":"Hepatectomy","level":3,"score":0.5266002416610718},{"id":"https://openalex.org/C2776637226","wikidata":"https://www.wikidata.org/wiki/Q6658207","display_name":"Liver injury","level":2,"score":0.5116305947303772},{"id":"https://openalex.org/C201716435","wikidata":"https://www.wikidata.org/wiki/Q15312697","display_name":"Liver receptor homolog-1","level":5,"score":0.48599037528038025},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.47667932510375977},{"id":"https://openalex.org/C167400880","wikidata":"https://www.wikidata.org/wiki/Q3454539","display_name":"Liver X receptor","level":5,"score":0.46325358748435974},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44978320598602295},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4206653833389282},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.404781311750412},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.33579015731811523},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22877007722854614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15251502394676208},{"id":"https://openalex.org/C159110652","wikidata":"https://www.wikidata.org/wiki/Q17078201","display_name":"Resection","level":2,"score":0.04984527826309204},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000099150","descriptor_name":"Receptor, Farnesoid X-Activated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001647","descriptor_name":"Bile Acids and Salts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001647","descriptor_name":"Bile Acids and Salts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001647","descriptor_name":"Bile Acids and Salts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001647","descriptor_name":"Bile Acids and Salts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001647","descriptor_name":"Bile Acids and Salts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbagrm.2014.05.021","doi":"https://doi.org/10.1016/j.bbagrm.2014.05.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbagrm.2014.05.021","pdf_url":null,"source":{"id":"https://openalex.org/S4210203689","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","issn_l":"1874-9399","issn":["1874-9399","1876-4320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","raw_type":"journal-article"},{"id":"pmid:24878541","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24878541","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4246016","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246016","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biochim Biophys Acta","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4246016","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246016","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biochim Biophys Acta","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.5400000214576721,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2025120831","display_name":null,"funder_award_id":"1R01-CA139158","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4342066672","display_name":null,"funder_award_id":"R01CA139158","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":83,"referenced_works":["https://openalex.org/W89320799","https://openalex.org/W1523071223","https://openalex.org/W1526691187","https://openalex.org/W1962935964","https://openalex.org/W1963587340","https://openalex.org/W1965796890","https://openalex.org/W1966056249","https://openalex.org/W1967056255","https://openalex.org/W1967235705","https://openalex.org/W1968243780","https://openalex.org/W1968928885","https://openalex.org/W1976621716","https://openalex.org/W1984936544","https://openalex.org/W1985539406","https://openalex.org/W1988914167","https://openalex.org/W1992585626","https://openalex.org/W1995457710","https://openalex.org/W1997933512","https://openalex.org/W1998420703","https://openalex.org/W2000595541","https://openalex.org/W2001058921","https://openalex.org/W2005786213","https://openalex.org/W2005933275","https://openalex.org/W2007486557","https://openalex.org/W2011600366","https://openalex.org/W2012294080","https://openalex.org/W2014681746","https://openalex.org/W2017362076","https://openalex.org/W2018400414","https://openalex.org/W2021283526","https://openalex.org/W2021444563","https://openalex.org/W2022493303","https://openalex.org/W2024197468","https://openalex.org/W2028530637","https://openalex.org/W2038366805","https://openalex.org/W2041451676","https://openalex.org/W2050841866","https://openalex.org/W2051040521","https://openalex.org/W2053581007","https://openalex.org/W2060532442","https://openalex.org/W2067834397","https://openalex.org/W2072104828","https://openalex.org/W2072813466","https://openalex.org/W2076100042","https://openalex.org/W2080519114","https://openalex.org/W2081028309","https://openalex.org/W2081271380","https://openalex.org/W2081359861","https://openalex.org/W2082184791","https://openalex.org/W2083073628","https://openalex.org/W2084215388","https://openalex.org/W2089491341","https://openalex.org/W2091544680","https://openalex.org/W2094417438","https://openalex.org/W2095536002","https://openalex.org/W2096418655","https://openalex.org/W2102459969","https://openalex.org/W2106513326","https://openalex.org/W2114226958","https://openalex.org/W2120383034","https://openalex.org/W2121227735","https://openalex.org/W2126396865","https://openalex.org/W2132001389","https://openalex.org/W2134818519","https://openalex.org/W2138532707","https://openalex.org/W2139256273","https://openalex.org/W2141176188","https://openalex.org/W2143805491","https://openalex.org/W2146012023","https://openalex.org/W2150274095","https://openalex.org/W2150717198","https://openalex.org/W2151488218","https://openalex.org/W2152035679","https://openalex.org/W2153813367","https://openalex.org/W2157776545","https://openalex.org/W2162888435","https://openalex.org/W2167120766","https://openalex.org/W2171398834","https://openalex.org/W2247149472","https://openalex.org/W4211043529","https://openalex.org/W4237329722","https://openalex.org/W6641948469","https://openalex.org/W6677021314"],"related_works":["https://openalex.org/W1990819179","https://openalex.org/W2183527314","https://openalex.org/W2472372932","https://openalex.org/W3029517394","https://openalex.org/W2024176527","https://openalex.org/W2156454518","https://openalex.org/W2117616183","https://openalex.org/W2027478520","https://openalex.org/W2005485506","https://openalex.org/W2387042716"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}