{"id":"https://openalex.org/W2005455346","doi":"https://doi.org/10.2165/00002512-199303020-00006","title":"Multicentre Study of l-??-Glyceryl-Phosphorylcholine vs ST200 among Patients with Probable Senile Dementia of Alzheimer??s Type","display_name":"Multicentre Study of l-??-Glyceryl-Phosphorylcholine vs ST200 among Patients with Probable Senile Dementia of Alzheimer??s Type","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2005455346","doi":"https://doi.org/10.2165/00002512-199303020-00006","mag":"2005455346","pmid":"https://pubmed.ncbi.nlm.nih.gov/8477148"},"language":"en","primary_location":{"id":"doi:10.2165/00002512-199303020-00006","doi":"https://doi.org/10.2165/00002512-199303020-00006","is_oa":false,"landing_page_url":"https://doi.org/10.2165/00002512-199303020-00006","pdf_url":null,"source":{"id":"https://openalex.org/S37256505","display_name":"Drugs & Aging","issn_l":"1170-229X","issn":["1170-229X","1179-1969"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs & Aging","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019846852","display_name":"Lucilla Parnetti","orcid":"https://orcid.org/0000-0001-5722-3967","observed_orcids":["https://orcid.org/0000-0001-5722-3967"]},"institutions":[{"id":"https://openalex.org/I27483092","display_name":"University of Perugia","ror":"https://ror.org/00x27da85","country_code":"IT","type":"education","lineage":["https://openalex.org/I27483092"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"L. Parnetti","raw_affiliation_strings":["Institute of Gerontology and Geriatrics, University of Perugia, Italy","University of Perugia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gerontology and Geriatrics, University of Perugia, Italy","institution_ids":["https://openalex.org/I27483092"]},{"raw_affiliation_string":"University of Perugia","institution_ids":["https://openalex.org/I27483092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113755538","display_name":"G Abate","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Abate","raw_affiliation_strings":["University of Chieti"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Chieti","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061905307","display_name":"Luisa Bartorelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Bartorelli","raw_affiliation_strings":["Geriatric Department, The City Hospital, Sezze Romano, Italy","The City Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geriatric Department, The City Hospital, Sezze Romano, Italy","institution_ids":[]},{"raw_affiliation_string":"The City Hospital","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005444334","display_name":"Domenico Cucinotta","orcid":"https://orcid.org/0000-0002-8159-5709","observed_orcids":["https://orcid.org/0000-0002-8159-5709"]},"institutions":[{"id":"https://openalex.org/I4210097083","display_name":"IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola","ror":"https://ror.org/00t4vnv68","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210097083"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D. Cucinotta","raw_affiliation_strings":["Geriatric Department, Malpighi Hospital, Bologna, Italy","Malpighi Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geriatric Department, Malpighi Hospital, Bologna, Italy","institution_ids":["https://openalex.org/I4210097083"]},{"raw_affiliation_string":"Malpighi Hospital","institution_ids":["https://openalex.org/I4210097083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057535357","display_name":"Marco Cuzzupoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Cuzzupoli","raw_affiliation_strings":["Geriatric Department, The City Hospital, Fano, Italy","The City Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geriatric Department, The City Hospital, Fano, Italy","institution_ids":[]},{"raw_affiliation_string":"The City Hospital","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Maggioni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Maggioni","raw_affiliation_strings":["Neurology Department, Zucchi Clinic, Carate Brianza, Italy","Zucchi Clinic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Department, Zucchi Clinic, Carate Brianza, Italy","institution_ids":[]},{"raw_affiliation_string":"Zucchi Clinic","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032932275","display_name":"Claudio Villardita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"C. Villardita","raw_affiliation_strings":["University of Catania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Catania","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011919079","display_name":"Umberto Senin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27483092","display_name":"University of Perugia","ror":"https://ror.org/00x27da85","country_code":"IT","type":"education","lineage":["https://openalex.org/I27483092"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"U. Senin","raw_affiliation_strings":["Institute of Gerontology and Geriatrics, University of Perugia, Via Eugubina 42, 06100, Perugia, Italy","University of Perugia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gerontology and Geriatrics, University of Perugia, Via Eugubina 42, 06100, Perugia, Italy","institution_ids":["https://openalex.org/I27483092"]},{"raw_affiliation_string":"University of Perugia","institution_ids":["https://openalex.org/I27483092"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":1.1546,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.76041219,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"3","issue":"2","first_page":"159","last_page":"164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.6563000082969666,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.6563000082969666,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.1873999983072281,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.093299999833107,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acetyl-l-carnitine","display_name":"acetyl-L-carnitine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.921999990940094},{"id":"https://openalex.org/keywords/senile-dementia-of-alzheimer-s-type","display_name":"senile dementia of Alzheimer's type","score":0.9129999876022339},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.6179999709129333},{"id":"https://openalex.org/keywords/neuropsychological-assessment","display_name":"neuropsychological assessment","score":0.699999988079071},{"id":"https://openalex.org/keywords/drug-efficacy","display_name":"drug efficacy","score":0.625},{"id":"https://openalex.org/keywords/tolerability","display_name":"tolerability","score":0.9520000219345093}],"concepts":[{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.8383780121803284},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7542039155960083},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6447681188583374},{"id":"https://openalex.org/C2776833585","wikidata":"https://www.wikidata.org/wiki/Q7187582","display_name":"Phosphorylcholine","level":2,"score":0.5964581370353699},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.5792874693870544},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.543603241443634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4630342721939087},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.432338148355484},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.31419849395751953},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2834824025630951},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.14415869116783142},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.08969202637672424},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000108","descriptor_name":"Acetylcarnitine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000108","descriptor_name":"Acetylcarnitine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001519","descriptor_name":"Behavior","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005997","descriptor_name":"Glycerylphosphorylcholine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005997","descriptor_name":"Glycerylphosphorylcholine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007361","descriptor_name":"Intelligence Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2165/00002512-199303020-00006","doi":"https://doi.org/10.2165/00002512-199303020-00006","is_oa":false,"landing_page_url":"https://doi.org/10.2165/00002512-199303020-00006","pdf_url":null,"source":{"id":"https://openalex.org/S37256505","display_name":"Drugs & Aging","issn_l":"1170-229X","issn":["1170-229X","1179-1969"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs & Aging","raw_type":"journal-article"},{"id":"pmid:8477148","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8477148","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs & aging","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W38490725","https://openalex.org/W1644143258","https://openalex.org/W1847168837","https://openalex.org/W1975693728","https://openalex.org/W1988721068","https://openalex.org/W1994131284","https://openalex.org/W2008854521","https://openalex.org/W2026113944","https://openalex.org/W2048978964","https://openalex.org/W2061378977","https://openalex.org/W2062017626","https://openalex.org/W2083873966","https://openalex.org/W2116407743","https://openalex.org/W2148080316","https://openalex.org/W2156220037","https://openalex.org/W2167311298","https://openalex.org/W2465155304","https://openalex.org/W2799379448"],"related_works":["https://openalex.org/W2121345124","https://openalex.org/W7030520168","https://openalex.org/W2078237207","https://openalex.org/W4317614440","https://openalex.org/W2156210987","https://openalex.org/W1987114124","https://openalex.org/W4402665614","https://openalex.org/W4231007743","https://openalex.org/W6958461146","https://openalex.org/W2034641659"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}