{"id":"https://openalex.org/W2005452197","doi":"https://doi.org/10.1016/j.bpj.2013.11.2001","title":"Crystal and EM Structures Reveal a Mechanism for Long-Range Allosteric Communication in the Yeast Dynein Motor Domain","display_name":"Crystal and EM Structures Reveal a Mechanism for Long-Range Allosteric Communication in the Yeast Dynein Motor Domain","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2005452197","doi":"https://doi.org/10.1016/j.bpj.2013.11.2001","mag":"2005452197"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2013.11.2001","doi":"https://doi.org/10.1016/j.bpj.2013.11.2001","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2013.11.2001","pdf_url":"http://www.cell.com/article/S0006349513032591/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349513032591/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046255159","display_name":"Hui\u2010Chun Cheng","orcid":"https://orcid.org/0000-0003-3591-8906","observed_orcids":["https://orcid.org/0000-0003-3591-8906"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui-Chun Cheng","raw_affiliation_strings":["Cellular and Molecular Pharmacology, Howard Hughes Medical Institute and University of California, San Francisco, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular and Molecular Pharmacology, Howard Hughes Medical Institute and University of California, San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066717627","display_name":"Gira Bhabha","orcid":"https://orcid.org/0000-0003-0624-6178","observed_orcids":["https://orcid.org/0000-0003-0624-6178"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gira Bhabha","raw_affiliation_strings":["Cellular and Molecular Pharmacology, Howard Hughes Medical Institute and University of California, San Francisco, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular and Molecular Pharmacology, Howard Hughes Medical Institute and University of California, San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110231653","display_name":"Ronald D. Vale","orcid":"https://orcid.org/0000-0003-3460-2758","observed_orcids":["https://orcid.org/0000-0003-3460-2758"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald D. Vale","raw_affiliation_strings":["Cellular and Molecular Pharmacology, Howard Hughes Medical Institute and University of California, San Francisco, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular and Molecular Pharmacology, Howard Hughes Medical Institute and University of California, San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09943747,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"106","issue":"2","first_page":"352a","last_page":"352a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dynein-motor-domain","display_name":"dynein motor domain","score":0.9729999899864197},{"id":"https://openalex.org/keywords/aaa-proteins","display_name":"AAA+ ATPase","score":0.796999990940094},{"id":"https://openalex.org/keywords/allosteric-communication","display_name":"allosteric communication","score":0.8650000095367432},{"id":"https://openalex.org/keywords/linker-conformation","display_name":"linker conformation","score":0.4950000047683716},{"id":"https://openalex.org/keywords/amp-pnp","display_name":"AMP-PNP","score":0.6320000290870667},{"id":"https://openalex.org/keywords/nucleotide-binding","display_name":"nucleotide binding","score":0.5899999737739563},{"id":"https://openalex.org/keywords/microtubule-binding","display_name":"microtubule binding","score":0.8960000276565552},{"id":"https://openalex.org/keywords/salt-bridges","display_name":"salt bridges","score":0.8230000138282776},{"id":"https://openalex.org/keywords/microtubule-based-motility","display_name":"microtubule motility","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C106987784","wikidata":"https://www.wikidata.org/wiki/Q410134","display_name":"Dynein","level":3,"score":0.9270612001419067},{"id":"https://openalex.org/C141315368","wikidata":"https://www.wikidata.org/wiki/Q4654881","display_name":"ATP hydrolysis","level":4,"score":0.7365469932556152},{"id":"https://openalex.org/C166342909","wikidata":"https://www.wikidata.org/wiki/Q845326","display_name":"Allosteric regulation","level":3,"score":0.7255878448486328},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.6154379844665527},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.5446829199790955},{"id":"https://openalex.org/C134729014","wikidata":"https://www.wikidata.org/wiki/Q21105411","display_name":"Dynactin","level":4,"score":0.536403477191925},{"id":"https://openalex.org/C2780557392","wikidata":"https://www.wikidata.org/wiki/Q523796","display_name":"Linker","level":2,"score":0.49433398246765137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48508134484291077},{"id":"https://openalex.org/C101635128","wikidata":"https://www.wikidata.org/wiki/Q4649768","display_name":"AAA proteins","level":4,"score":0.4749365448951721},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4640796184539795},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33840566873550415},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32148104906082153},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2976427674293518},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.14805537462234497},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bpj.2013.11.2001","doi":"https://doi.org/10.1016/j.bpj.2013.11.2001","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2013.11.2001","pdf_url":"http://www.cell.com/article/S0006349513032591/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2013.11.2001","doi":"https://doi.org/10.1016/j.bpj.2013.11.2001","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2013.11.2001","pdf_url":"http://www.cell.com/article/S0006349513032591/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/7","score":0.47999998927116394,"display_name":"Affordable and clean energy"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2005452197.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2058768471","https://openalex.org/W2084476197","https://openalex.org/W2111004920","https://openalex.org/W2947259376","https://openalex.org/W2948019509","https://openalex.org/W2949316305","https://openalex.org/W2077510976","https://openalex.org/W2137065909","https://openalex.org/W2067362525","https://openalex.org/W2993549909"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}