{"id":"https://openalex.org/W2005442840","doi":"https://doi.org/10.1111/jch.12388","title":"Calcium Channel Blocker Compared With Angiotensin Receptor Blocker for Patients With Hypertension: A Meta\u2010Analysis of Randomized Controlled Trials","display_name":"Calcium Channel Blocker Compared With Angiotensin Receptor Blocker for Patients With Hypertension: A Meta\u2010Analysis of Randomized Controlled Trials","publication_year":2014,"publication_date":"2014-08-07","ids":{"openalex":"https://openalex.org/W2005442840","doi":"https://doi.org/10.1111/jch.12388","mag":"2005442840","pmid":"https://pubmed.ncbi.nlm.nih.gov/25098737","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8031805"},"language":"en","primary_location":{"id":"doi:10.1111/jch.12388","doi":"https://doi.org/10.1111/jch.12388","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jch.12388","pdf_url":null,"source":{"id":"https://openalex.org/S154226970","display_name":"Journal of Clinical Hypertension","issn_l":"1524-6175","issn":["1524-6175","1751-7176"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Hypertension","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2005442840"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8031805/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071526701","display_name":"Ling Wu","orcid":"https://orcid.org/0000-0001-6574-6493","observed_orcids":["https://orcid.org/0000-0001-6574-6493"]},"institutions":[{"id":"https://openalex.org/I4210097509","display_name":"Second Affiliated Hospital of Chongqing Medical University","ror":"https://ror.org/00r67fz39","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097509"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ling Wu","raw_affiliation_strings":["Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210097509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104235459","display_name":"Songbai Deng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097509","display_name":"Second Affiliated Hospital of Chongqing Medical University","ror":"https://ror.org/00r67fz39","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097509"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Song\u2010Bai Deng","raw_affiliation_strings":["Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210097509"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100779431","display_name":"Qiang She","orcid":"https://orcid.org/0000-0001-5049-1264","observed_orcids":["https://orcid.org/0000-0001-5049-1264"]},"institutions":[{"id":"https://openalex.org/I4210097509","display_name":"Second Affiliated Hospital of Chongqing Medical University","ror":"https://ror.org/00r67fz39","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097509"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiang She","raw_affiliation_strings":["Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I4210097509"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100779431"],"corresponding_institution_ids":["https://openalex.org/I4210097509"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":0.2108,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.25345863,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"16","issue":"11","first_page":"838","last_page":"845"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.9580000042915344},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9570000171661377},{"id":"https://openalex.org/keywords/stroke-prevention","display_name":"stroke prevention","score":0.8629999756813049},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9729999899864197},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9890000224113464},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9829999804496765},{"id":"https://openalex.org/keywords/antihypertensive-therapy-comparison","display_name":"antihypertensive therapy comparison","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9294323921203613},{"id":"https://openalex.org/C2780356492","wikidata":"https://www.wikidata.org/wiki/Q421700","display_name":"Calcium channel blocker","level":3,"score":0.8143829107284546},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6446518898010254},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6432238221168518},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6387813091278076},{"id":"https://openalex.org/C104849204","wikidata":"https://www.wikidata.org/wiki/Q24778533","display_name":"Angiotensin receptor","level":4,"score":0.6339366436004639},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.6312165260314941},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5682920217514038},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5047606229782104},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5024800300598145},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.4375697672367096},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.2856305241584778},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.23608562350273132},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.10780656337738037},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057911","descriptor_name":"Angiotensin Receptor Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/jch.12388","doi":"https://doi.org/10.1111/jch.12388","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jch.12388","pdf_url":null,"source":{"id":"https://openalex.org/S154226970","display_name":"Journal of Clinical Hypertension","issn_l":"1524-6175","issn":["1524-6175","1751-7176"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Hypertension","raw_type":"journal-article"},{"id":"pmid:25098737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25098737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical hypertension (Greenwich, Conn.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8031805","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8031805/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Hypertens (Greenwich)","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8031805","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8031805/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Hypertens (Greenwich)","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1247968195","https://openalex.org/W1497461844","https://openalex.org/W1980967898","https://openalex.org/W1985716618","https://openalex.org/W2013354239","https://openalex.org/W2037190492","https://openalex.org/W2044773944","https://openalex.org/W2051977633","https://openalex.org/W2074847395","https://openalex.org/W2087435181","https://openalex.org/W2090524160","https://openalex.org/W2103296053","https://openalex.org/W2105621437","https://openalex.org/W2106073810","https://openalex.org/W2108486578","https://openalex.org/W2117140855","https://openalex.org/W2117226050","https://openalex.org/W2118194784","https://openalex.org/W2126045082","https://openalex.org/W2126125759","https://openalex.org/W2133416234","https://openalex.org/W2136115956","https://openalex.org/W2137302107","https://openalex.org/W2140926653","https://openalex.org/W2146798390","https://openalex.org/W2165010366","https://openalex.org/W2167557672","https://openalex.org/W2170020414","https://openalex.org/W2172032309","https://openalex.org/W2403543360","https://openalex.org/W2598936606","https://openalex.org/W4232071938"],"related_works":["https://openalex.org/W2575008822","https://openalex.org/W2020695520","https://openalex.org/W2316297009","https://openalex.org/W2161847205","https://openalex.org/W2374290384","https://openalex.org/W2090524160","https://openalex.org/W4291007321","https://openalex.org/W1969114520","https://openalex.org/W2399937189"],"abstract_inverted_index":{"To":[0],"explore":[1],"the":[2,20,55,103],"clinical":[3],"effects":[4],"of":[5,132,148],"a":[6,107,133],"calcium":[7,66,134],"channel":[8,67,135],"blocker":[9,16,136,145],"compared":[10],"with":[11,98,112],"an":[12,141],"angiotensin":[13,113,142],"II":[14,114,143],"receptor":[15,115,144],"in":[17,54,72,110],"hypertensive":[18],"patients,":[19],"authors":[21],"collected":[22],"data":[23],"from":[24],"randomized":[25],"controlled":[26],"trials.":[27],"The":[28,126],"pooled":[29],"outcomes":[30],"were":[31,46,69],"all-cause":[32],"mortality,":[33],"stroke,":[34],"myocardial":[35,83,151],"infarction,":[36],"and":[37,82,150],"heart":[38,99],"failure.":[39],"Eight":[40],"head-to-head":[41],"trials":[42],"enrolling":[43],"25,084":[44],"patients":[45,111],"included.":[47],"There":[48,93],"was":[49,94,117],"no":[50,95],"significant":[51,96],"mortality":[52],"difference":[53,97],"two":[56,104],"arms":[57,105],"(relative":[58,75,86,119],"risk,":[59,76,87,120],"0.99;":[60],"95%":[61,78,89,122],"confidence":[62,79,90,123],"interval,":[63,80,91,124],"0.91-1.07).":[64],"However,":[65],"blockers":[68,116],"more":[70],"effective":[71],"reducing":[73],"stroke":[74,149],"0.87;":[77],"0.76-0.99)":[81],"infarction":[84],"incidence":[85,101],"0.86;":[88],"0.76-0.98).":[92],"failure":[100],"between":[102],"but":[106],"lower":[108],"trend":[109],"noted":[118],"1.4;":[121],"0.99-1.98).":[125],"meta-analysis":[127],"suggested":[128],"that":[129],"initially":[130],"use":[131],"might":[137],"be":[138],"superior":[139],"to":[140],"for":[146],"prevention":[147],"infarction.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}