{"id":"https://openalex.org/W2005415088","doi":"https://doi.org/10.1007/s00223-011-9462-8","title":"Minerals Form a Continuum Phase in Mature Cancellous Bone","display_name":"Minerals Form a Continuum Phase in Mature Cancellous Bone","publication_year":2011,"publication_date":"2011-01-27","ids":{"openalex":"https://openalex.org/W2005415088","doi":"https://doi.org/10.1007/s00223-011-9462-8","mag":"2005415088","pmid":"https://pubmed.ncbi.nlm.nih.gov/21274705"},"language":"en","primary_location":{"id":"doi:10.1007/s00223-011-9462-8","doi":"https://doi.org/10.1007/s00223-011-9462-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00223-011-9462-8","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00223-011-9462-8.pdf","source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00223-011-9462-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100767279","display_name":"Po\u2010Yu Chen","orcid":"https://orcid.org/0000-0002-0375-0718","observed_orcids":["https://orcid.org/0000-0002-0375-0718"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Po-Yu Chen","raw_affiliation_strings":["Materials Science and Engineering Program, Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0411, USA. pochen@ucsd.edu","University of California,  San Diego"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Materials Science and Engineering Program, Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0411, USA. pochen@ucsd.edu","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California,  San Diego","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049739846","display_name":"Damon Toroian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Damon Toroian","raw_affiliation_strings":["Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0322, USA","University of California,  San Diego"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0322, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California,  San Diego","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065198053","display_name":"Paul A. Price","orcid":"https://orcid.org/0000-0002-6001-3941","observed_orcids":["https://orcid.org/0000-0002-6001-3941"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A. Price","raw_affiliation_strings":["Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0322, USA","University of California,  San Diego"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0322, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California,  San Diego","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044738960","display_name":"Joanna M. McKittrick","orcid":"https://orcid.org/0000-0002-1442-3472","observed_orcids":["https://orcid.org/0000-0002-1442-3472"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanna McKittrick","raw_affiliation_strings":["Materials Science and Engineering Program, Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0411, USA","University of California,  San Diego"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Materials Science and Engineering Program, Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0411, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California,  San Diego","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100767279"],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":{"value":3990,"currency":"USD","value_usd":3990},"fwci":7.1351,"has_fulltext":true,"cited_by_count":128,"citation_normalized_percentile":{"value":0.97646049,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"88","issue":"5","first_page":"351","last_page":"361"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.5443999767303467,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.5443999767303467,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.399399995803833,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11278","display_name":"Calcium Carbonate Crystallization and Inhibition","score":0.021700000390410423,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-mineral-structure","display_name":"bone mineral structure","score":0.6890000104904175},{"id":"https://openalex.org/keywords/trabecular-bone","display_name":"trabecular bone","score":0.9570000171661377},{"id":"https://openalex.org/keywords/deproteinization","display_name":"deproteinization","score":0.5730000138282776},{"id":"https://openalex.org/keywords/carbonated-apatite","display_name":"carbonated hydroxyapatite","score":0.8679999709129333},{"id":"https://openalex.org/keywords/type-i-collagen","display_name":"type I collagen","score":0.7609999775886536},{"id":"https://openalex.org/keywords/trabecular-bone-microarchitecture","display_name":"trabecular bone microarchitecture","score":0.6399999856948853},{"id":"https://openalex.org/keywords/hierarchy","display_name":"hierarchy","score":0.6510000228881836},{"id":"https://openalex.org/keywords/compressive-deformation","display_name":"compressive deformation","score":0.7099999785423279},{"id":"https://openalex.org/keywords/bio-oss","display_name":"Bio-Oss","score":0.8109999895095825},{"id":"https://openalex.org/keywords/bovine-femur","display_name":"bovine femur","score":0.9190000295639038}],"concepts":[{"id":"https://openalex.org/C2777746296","wikidata":"https://www.wikidata.org/wiki/Q178397","display_name":"Apatite","level":2,"score":0.6883065700531006},{"id":"https://openalex.org/C2776350087","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cancellous bone","level":2,"score":0.6690971255302429},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.593584418296814},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.544823408126831},{"id":"https://openalex.org/C2780554211","wikidata":"https://www.wikidata.org/wiki/Q176503","display_name":"Femur","level":2,"score":0.5154153108596802},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.43906962871551514},{"id":"https://openalex.org/C137637335","wikidata":"https://www.wikidata.org/wiki/Q899604","display_name":"Crystallite","level":2,"score":0.4257006049156189},{"id":"https://openalex.org/C199289684","wikidata":"https://www.wikidata.org/wiki/Q83353","display_name":"Mineralogy","level":1,"score":0.37979769706726074},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.3476969599723816},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34713566303253174},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.2930828928947449},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.258736252784729},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.14691442251205444},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.11752015352249146},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0882256031036377},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07481268048286438},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018775","descriptor_name":"Bone Demineralization Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018775","descriptor_name":"Bone Demineralization Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018775","descriptor_name":"Bone Demineralization Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023421","descriptor_name":"Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023421","descriptor_name":"Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023421","descriptor_name":"Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00223-011-9462-8","doi":"https://doi.org/10.1007/s00223-011-9462-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00223-011-9462-8","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00223-011-9462-8.pdf","source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue International","raw_type":"journal-article"},{"id":"pmid:21274705","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21274705","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified tissue international","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3075393","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3075393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Calcif Tissue Int","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s00223-011-9462-8","doi":"https://doi.org/10.1007/s00223-011-9462-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00223-011-9462-8","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00223-011-9462-8.pdf","source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue International","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1363218302","display_name":"Mechanical Properties and Structure of Abalone: Self-Assembled Ceramic Nanostructures","funder_award_id":"0510138","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G2827926175","display_name":null,"funder_award_id":"W911-08-1-0461","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G4816000201","display_name":"FRG: Bioinspired Synthesis of Tough Laminates","funder_award_id":"1006931","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G527069472","display_name":null,"funder_award_id":"DMR 0510138","funder_id":"https://openalex.org/F4320337367","funder_display_name":"Division of Materials Research"},{"id":"https://openalex.org/G6467914805","display_name":null,"funder_award_id":"1006931","funder_id":"https://openalex.org/F4320337367","funder_display_name":"Division of Materials Research"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337367","display_name":"Division of Materials Research","ror":"https://ror.org/01pc7k308"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005415088.pdf","grobid_xml":"https://content.openalex.org/works/W2005415088.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W35508769","https://openalex.org/W45587185","https://openalex.org/W89664697","https://openalex.org/W1556186925","https://openalex.org/W1969293769","https://openalex.org/W1972190722","https://openalex.org/W1976842902","https://openalex.org/W1979365147","https://openalex.org/W1980119297","https://openalex.org/W1983045854","https://openalex.org/W1984535514","https://openalex.org/W2001741437","https://openalex.org/W2002028623","https://openalex.org/W2006629115","https://openalex.org/W2011022570","https://openalex.org/W2013322752","https://openalex.org/W2013453106","https://openalex.org/W2020641822","https://openalex.org/W2025565744","https://openalex.org/W2027733328","https://openalex.org/W2030661062","https://openalex.org/W2030995263","https://openalex.org/W2040957028","https://openalex.org/W2042245951","https://openalex.org/W2042732214","https://openalex.org/W2047616179","https://openalex.org/W2050592185","https://openalex.org/W2053596687","https://openalex.org/W2054163292","https://openalex.org/W2054271456","https://openalex.org/W2056230919","https://openalex.org/W2061338754","https://openalex.org/W2066646366","https://openalex.org/W2070813176","https://openalex.org/W2075952001","https://openalex.org/W2092055337","https://openalex.org/W2110508763","https://openalex.org/W2127000141","https://openalex.org/W2130971715","https://openalex.org/W2150238384","https://openalex.org/W2152411626","https://openalex.org/W2159193896","https://openalex.org/W2312294193","https://openalex.org/W2492661641","https://openalex.org/W4211160782","https://openalex.org/W4235825625","https://openalex.org/W4235897932"],"related_works":["https://openalex.org/W2355862987","https://openalex.org/W2465723261","https://openalex.org/W2049757704","https://openalex.org/W2402697569","https://openalex.org/W1993098890","https://openalex.org/W2070141875","https://openalex.org/W2326185588","https://openalex.org/W1970838757","https://openalex.org/W2355994828","https://openalex.org/W2416503907"],"abstract_inverted_index":{"Bone":[0],"is":[1,47,52,100,187],"a":[2,8,15,127,131],"hierarchically":[3],"structured":[4],"composite":[5,182],"consisting":[6],"of":[7,22,31,78,85,112,184],"protein":[9,55,115],"phase":[10,17],"(type":[11],"I":[12],"collagen)":[13],"and":[14,49,59,88,102,114,125,151,171,189],"mineral":[16,32,113,177],"(carbonated":[18],"apatite).":[19],"The":[20],"objective":[21],"this":[23],"study":[24],"was":[25],"to":[26,38,66,73,75],"investigate":[27],"the":[28,44,50,68,103,109],"hierarchical":[29,144],"structure":[30,46,129],"in":[33,130,175],"mature":[34,185],"bone.":[35,82],"A":[36,179],"method":[37],"completely":[39],"deproteinize":[40],"bone":[41,93,120,169,176,186],"without":[42],"altering":[43],"original":[45],"developed,":[48],"completion":[51],"confirmed":[53],"by":[54],"analysis":[56],"techniques.":[57],"Stereoscopy":[58],"field":[60],"emission":[61],"electron":[62],"microscopy":[63],"are":[64,106,122,140,148],"used":[65],"examine":[67],"structural":[69,110],"features":[70,105],"from":[71],"submillimeter-":[72],"micrometer-":[74],"nanometer-length":[76],"scales":[77],"bovine":[79,90],"femur":[80,91],"cancellous":[81,92],"Stereoscopic":[83],"images":[84],"fully":[86],"deproteinized":[87],"demineralized":[89],"samples":[94],"show":[95],"that":[96,119],"fine":[97],"trabecular":[98],"architecture":[99],"unaltered":[101],"microstructural":[104],"preserved,":[107],"indicating":[108],"integrity":[111],"constituents.":[116],"SEM":[117],"revealed":[118],"minerals":[121],"fused":[123],"together":[124],"form":[126],"sheet-like":[128],"coherent":[132],"manner":[133],"with":[134,165],"collagen":[135],"fibrils.":[136],"Well-organized":[137],"pore":[138],"systems":[139],"observed":[141],"at":[142],"varying":[143],"levels.":[145],"Mineral":[146],"sheets":[147],"peeled":[149],"off":[150],"folded":[152],"after":[153],"compressive":[154],"deformation,":[155],"implying":[156],"strong":[157],"connection":[158],"between":[159],"individual":[160],"crystallites.":[161],"Results":[162],"were":[163],"compared":[164],"commercially":[166],"available":[167],"heat-deproteinized":[168],"(Bio-Oss(\u00ae)),":[170],"evidence":[172],"showed":[173],"consistency":[174],"structure.":[178],"two-phase":[180],"interpenetrating":[181],"model":[183],"proposed":[188],"discussed.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":11}],"updated_date":"2026-10-04T09:36:47.201465","created_date":"2025-10-10T00:00:00"}