{"id":"https://openalex.org/W2005412282","doi":"https://doi.org/10.1136/hrt.47.1.19","title":"Interrelation of heart rate and autonomic activity in asymptomatic men with unobstructed coronary arteries. Studies with atrial pacing, adrenaline infusion, and autonomic blockade.","display_name":"Interrelation of heart rate and autonomic activity in asymptomatic men with unobstructed coronary arteries. Studies with atrial pacing, adrenaline infusion, and autonomic blockade.","publication_year":1982,"publication_date":"1982-01-01","ids":{"openalex":"https://openalex.org/W2005412282","doi":"https://doi.org/10.1136/hrt.47.1.19","mag":"2005412282","pmid":"https://pubmed.ncbi.nlm.nih.gov/7055508","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/481090"},"language":"en","primary_location":{"id":"doi:10.1136/hrt.47.1.19","doi":"https://doi.org/10.1136/hrt.47.1.19","is_oa":true,"landing_page_url":"https://doi.org/10.1136/hrt.47.1.19","pdf_url":"https://heart.bmj.com/content/heartjnl/47/1/19.full.pdf","source":{"id":"https://openalex.org/S191565391","display_name":"Heart","issn_l":"1355-6037","issn":["1355-6037","1468-201X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://heart.bmj.com/content/heartjnl/47/1/19.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008694213","display_name":"Peter I. Taggart","orcid":"https://orcid.org/0000-0001-8861-9227","observed_orcids":["https://orcid.org/0000-0001-8861-9227"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P Taggart","raw_affiliation_strings":["Departnent of Cardiology , The Middlesex Hospital , London ;","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departnent of Cardiology , The Middlesex Hospital , London ;","institution_ids":[]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111986474","display_name":"R Donaldson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R Donaldson","raw_affiliation_strings":["Departnent of Cardiology , The Middlesex Hospital , London ;","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departnent of Cardiology , The Middlesex Hospital , London ;","institution_ids":[]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028848692","display_name":"J Green","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J Green","raw_affiliation_strings":["Departnent of Cardiology , The Middlesex Hospital , London ;","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departnent of Cardiology , The Middlesex Hospital , London ;","institution_ids":[]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112583574","display_name":"S P Joseph","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S P Joseph","raw_affiliation_strings":["The Royal Air Force Central Medical Establishment ; and The University Laboratory ofPhysiology , Oxford","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Royal Air Force Central Medical Establishment ; and The University Laboratory ofPhysiology , Oxford","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H B Kelly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H B Kelly","raw_affiliation_strings":["From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036859978","display_name":"J Marcomichelakis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J Marcomichelakis","raw_affiliation_strings":["Departnent of Cardiology , The Middlesex Hospital , London ;","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departnent of Cardiology , The Middlesex Hospital , London ;","institution_ids":[]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050244394","display_name":"Denis Noble","orcid":"https://orcid.org/0000-0002-3013-3694","observed_orcids":["https://orcid.org/0000-0002-3013-3694"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D Noble","raw_affiliation_strings":["Departnent of Cardiology , The Middlesex Hospital , London ;","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departnent of Cardiology , The Middlesex Hospital , London ;","institution_ids":[]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":null,"display_name":"J White","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210131790","display_name":"Central Middlesex Hospital","ror":"https://ror.org/03mq8zc85","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210131790"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J White","raw_affiliation_strings":["Departnent of Cardiology , The Middlesex Hospital , London ;","From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","The University Laboratory ofPhysiology, Oxford"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departnent of Cardiology , The Middlesex Hospital , London ;","institution_ids":[]},{"raw_affiliation_string":"From the Departnent of Cardiology, The Middlesex Hospital, London; The Royal Air Force Central Medical Establishment; and","institution_ids":["https://openalex.org/I4210131790"]},{"raw_affiliation_string":"The University Laboratory ofPhysiology, Oxford","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8052,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.73537924,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"47","issue":"1","first_page":"19","last_page":"25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.08110000193119049,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13381","display_name":"Heart rate and cardiovascular health","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.8450000286102295},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"autonomic nervous system","score":0.75},{"id":"https://openalex.org/keywords/atrial-pacing","display_name":"atrial pacing","score":0.7390000224113464},{"id":"https://openalex.org/keywords/adrenaline-infusion","display_name":"adrenaline infusion","score":0.9229999780654907},{"id":"https://openalex.org/keywords/beta-adrenergic-blockade","display_name":"beta-adrenergic blockade","score":0.8309999704360962},{"id":"https://openalex.org/keywords/propranolol","display_name":"propranolol","score":0.9810000061988831},{"id":"https://openalex.org/keywords/atropine","display_name":"atropine","score":0.996999979019165},{"id":"https://openalex.org/keywords/t-wave-abnormalities","display_name":"T wave changes","score":0.7170000076293945},{"id":"https://openalex.org/keywords/st-segment-depression","display_name":"ST-segment depression","score":0.9589999914169312},{"id":"https://openalex.org/keywords/resting-electrocardiogram","display_name":"resting electrocardiogram","score":0.7300000190734863},{"id":"https://openalex.org/keywords/asymptomatic-men","display_name":"asymptomatic men","score":0.6850000023841858},{"id":"https://openalex.org/keywords/catecholamines","display_name":"catecholamines","score":0.7160000205039978},{"id":"https://openalex.org/keywords/exercise-testing","display_name":"exercise testing","score":0.4959999918937683},{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.593999981880188},{"id":"https://openalex.org/keywords/coronary-arteries","display_name":"coronary arteries","score":0.4490000009536743},{"id":"https://openalex.org/keywords/autonomic-blockade","display_name":"autonomic blockade","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9625226259231567},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.7577081918716431},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6870414018630981},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6704601049423218},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.6213638782501221},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.6005493998527527},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.4256402254104614},{"id":"https://openalex.org/C2778742706","wikidata":"https://www.wikidata.org/wiki/Q18361829","display_name":"Coronary arteries","level":3,"score":0.41198045015335083},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3656854033470154},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.19543898105621338},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.17567506432533264},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.06158280372619629}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001285","descriptor_name":"Atropine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005080","descriptor_name":"Exercise Test","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011433","descriptor_name":"Propranolol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1136/hrt.47.1.19","doi":"https://doi.org/10.1136/hrt.47.1.19","is_oa":true,"landing_page_url":"https://doi.org/10.1136/hrt.47.1.19","pdf_url":"https://heart.bmj.com/content/heartjnl/47/1/19.full.pdf","source":{"id":"https://openalex.org/S191565391","display_name":"Heart","issn_l":"1355-6037","issn":["1355-6037","1468-201X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:481090","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/481090","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br Heart J","raw_type":"Text"},{"id":"pmid:7055508","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7055508","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British heart journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1136/hrt.47.1.19","doi":"https://doi.org/10.1136/hrt.47.1.19","is_oa":true,"landing_page_url":"https://doi.org/10.1136/hrt.47.1.19","pdf_url":"https://heart.bmj.com/content/heartjnl/47/1/19.full.pdf","source":{"id":"https://openalex.org/S191565391","display_name":"Heart","issn_l":"1355-6037","issn":["1355-6037","1468-201X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005412282.pdf","grobid_xml":"https://content.openalex.org/works/W2005412282.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W26081196","https://openalex.org/W1494649290","https://openalex.org/W1974463823","https://openalex.org/W2004131331","https://openalex.org/W2039100506","https://openalex.org/W2045436525","https://openalex.org/W2098758600","https://openalex.org/W2102779899","https://openalex.org/W2149557409","https://openalex.org/W2275378255","https://openalex.org/W2346472115","https://openalex.org/W6601013106"],"related_works":["https://openalex.org/W2098758600","https://openalex.org/W2253145974","https://openalex.org/W1970090693","https://openalex.org/W2057294013","https://openalex.org/W1993146946","https://openalex.org/W2077638279","https://openalex.org/W2005643974","https://openalex.org/W2401278400","https://openalex.org/W6985055424","https://openalex.org/W2061538833"],"abstract_inverted_index":{"We":[0],"have":[1,79,308,410],"extended":[2],"our":[3],"observations":[4,310],"on":[5,157,211,229,311,386],"asymptomatic":[6,68,312,402],"men":[7,313],"with":[8,22,203,320,348],"abnormal":[9,321],"resting":[10,292],"elec-":[11],"trocardiograms":[12],"showing":[13,323],"changes":[14,123,286,317,324,379],"indistinguishable":[15,334],"from":[16,39,335],"those":[17,40,336],"of":[18,35,41,50,175,197,214,226,278,282,337,370,401,408],"myocardial":[19,338],"ischaemia":[20,339],"but":[21,205,257,273,347],"normal":[23,85,126,349],"coronary":[24,82,350],"arteriograms.In":[25],"the":[26,33,42,48,99,142,158,173,176,184,188,195,212,224,230,259,264,276,279,291,362,374,377,387,413],"present":[27],"investigation":[28],"we":[29],"aimed":[30],"to":[31,72,78,118,125,137,153,269,358,360,364,394],"separate":[32],"effects":[34,49,156],"heart":[36,302,319],"rate":[37,271,303,325],"alone":[38],"sympathetic":[43,329,396],"nervous":[44],"system.We":[45],"therefore":[46],"studied":[47],"atrial":[51,135,169,227,416],"pacing":[52,54,59,63,136,170,182,204,215,228],"alone,":[53],"and":[55,62,84,110,163,168,181,199,239,287,304,314,373],"adrenaline":[56,145,180,198,419],"infusion":[57,407],"combined,":[58],"after":[60,64,129,219],"beta-blockade,":[61],"beta-blockade":[65,243,250],"plus":[66],"atropine.Twenty":[67],"men,":[69],"aged":[70],"17":[71],"57,":[73],"were":[74,76,90,235,248],"investigated.All":[75],"shown":[77],"unob-":[80],"structed":[81],"arteries":[83],"left":[86],"ventricular":[87],"angiograms.Echocardiographic":[88],"findings":[89],"normal.Sixteen":[91],"had":[92,105,112],"flat":[93],"or":[94,127,140,344],"inverted":[95],"T":[96,284],"waves":[97],"in":[98,133,148,187,237,241,290,295,318,345,390],"lateral":[100],"leads":[101],"(designated":[102,108],"\"T\"),":[103],"two":[104,111],"ST":[106,122,255,288],"depression":[107,256,289],"\"ST\"),":[109],"mixed":[113],"patterns.T":[114],"wave":[115,285],"abnormalities":[116],"and,":[117],"a":[119,391],"lesser":[120],"extent,":[121],"returned":[124],"regressed":[128],"an":[130],"overnight":[131],"rest":[132],"hospital.Subsequent":[134],"160/minute":[138],"reproduced":[139],"increased":[141],"respective":[143],"abnormalities.When":[144],"was":[146,171,178,367],"infused":[147],"low":[149],"doses":[150],"just":[151],"sufficient":[152],"produce":[154],"discernible":[155],"ST-T":[159,185,231],"segment":[160,186],"(between":[161],"0-024":[162],"0*091":[164],",ug/kg":[165],"per":[166],"min)":[167],"repeated,":[172],"effect":[174,196,202,213,225,369],"latter":[177,265],"enhanced.Both":[179],"influenced":[183,299],"same":[189],"direction.Intravenous":[190],"propranolol":[191,220],"(0.2":[192],"mg/kg)":[193,222],"blocked":[194],"its":[200],"synergistic":[201],"exerted":[206],"little":[207],"if":[208],"any":[209],"influence":[210,281,395],"alone.Atropine":[216],"given":[217],"intravenously":[218],"(0.04":[221],"reduced":[223],"configuration.Treadmill":[232],"exercise":[233,262],"tests":[234,247],"positive":[236,261],"nine":[238],"borderline":[240],"one.After":[242],"(oral":[244],"oxprenolol),":[245],"all":[246],"negative.As":[249],"did":[251],"not":[252,267],"prevent":[253],"pacing-induced":[254],"normalised":[258],"false":[260],"test,":[263],"does":[266],"appear":[268],"be":[270,332,381],"related":[272],"more":[274],"probably":[275],"result":[277],"direct":[280],"catecholamines.Isolated":[283],"electrocardiogram":[293,414],"differ":[294],"that":[296],"they":[297],"are":[298],"both":[300],"by":[301,384],"catecholamines":[305],"acting":[306,341],"synergistically.We":[307],"reported":[309],"beta-adrenergic":[315],"blockade.Since":[316],"electrocardiograms":[322],"as":[326,328,404],"well":[327],"behaviour":[330],"may":[331],"relevant,":[333],"however,":[340],"either":[342],"independently":[343],"combina-":[346],"arteriograms.1":[351],"An":[352],"altered":[353],"tion,":[354],"it":[355],"seemed":[356],"appropriate":[357],"attempt":[359],"evaluate":[361],"response":[363],"autonomic":[365],"activity":[366],"show,.whereby":[368],"each":[371],"separately":[372],"interplay":[375],"between":[376],"these":[378],"could":[380],"readily":[382],"manipulated":[383],"meas-two":[385],"electrocardiographic":[388],"configuration":[389],"ures":[392],"designed":[393],"activity,":[397],"such":[398],"similar":[399],"group":[400],"men.":[403],"tranquillity,":[405],"intravenous":[406,418],"adrenaline,We":[409],"accordingly":[411],"recorded":[412],"during":[415],"pacing,":[417]},"counts_by_year":[{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}