{"id":"https://openalex.org/W2005408582","doi":"https://doi.org/10.1111/j.1749-6632.1966.tb41203.x","title":"ROLE OF ALDOSTERONE IN EDEMA FORMATION","display_name":"ROLE OF ALDOSTERONE IN EDEMA FORMATION","publication_year":1966,"publication_date":"1966-11-01","ids":{"openalex":"https://openalex.org/W2005408582","doi":"https://doi.org/10.1111/j.1749-6632.1966.tb41203.x","mag":"2005408582","pmid":"https://pubmed.ncbi.nlm.nih.gov/4291331"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1966.tb41203.x","doi":"https://doi.org/10.1111/j.1749-6632.1966.tb41203.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1966.tb41203.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103455963","display_name":"Hanns P. Wolff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. P. Wolff","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013759620","display_name":"Ludwig Bette","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"L. Bette","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110004158","display_name":"H. Blaise","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Blaise","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004454562","display_name":"Gisela D\u00fcsterdieck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. D\u00fcsterdieck","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089179427","display_name":"Joachim Jahnecke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J. Jahnecke","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036021612","display_name":"Tatsuya Kobayashi","orcid":"https://orcid.org/0000-0001-5072-6756","observed_orcids":["https://orcid.org/0000-0001-5072-6756"]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Kobayashi","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027693123","display_name":"F. Kr\u00fcck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"F. Kr\u00fcck","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001962410","display_name":"DIETMAR LOMMER","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D. Lommer","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5114260447","display_name":"Hermann J. Schieffer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Schieffer","raw_affiliation_strings":["I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universita\u0308t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]},{"raw_affiliation_string":"I. and II. Medizinische Klinik der Universit\u00e4t des Saarlandes, Homburg/Saar, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":5.3281,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.94725511,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"139","issue":"2","first_page":"285","last_page":"294"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aldosterone","display_name":"aldosterone","score":1.0},{"id":"https://openalex.org/keywords/edema-formation","display_name":"edema formation","score":0.8510000109672546},{"id":"https://openalex.org/keywords/sodium-retention","display_name":"sodium retention","score":0.8610000014305115},{"id":"https://openalex.org/keywords/water-retention","display_name":"water retention","score":0.6570000052452087},{"id":"https://openalex.org/keywords/mineralocorticoids","display_name":"mineralocorticoids","score":0.6790000200271606},{"id":"https://openalex.org/keywords/sodium-balance","display_name":"sodium balance","score":0.367000013589859}],"concepts":[{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.37856364250183105},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.35287225246429443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3280802369117737}],"mesh":[{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000804","descriptor_name":"Angiotensin II","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D004487","descriptor_name":"Edema","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006929","descriptor_name":"Hyperaldosteronism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012636","descriptor_name":"Secretory Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1749-6632.1966.tb41203.x","doi":"https://doi.org/10.1111/j.1749-6632.1966.tb41203.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1966.tb41203.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:4291331","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4291331","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.428600013256073,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1964173162","https://openalex.org/W2036340454","https://openalex.org/W2073504974","https://openalex.org/W2084591577","https://openalex.org/W2093520818","https://openalex.org/W2103596394","https://openalex.org/W2133024613","https://openalex.org/W2140533239","https://openalex.org/W2419567729","https://openalex.org/W2481978272"],"related_works":["https://openalex.org/W2123101889","https://openalex.org/W2404956683","https://openalex.org/W2402412515","https://openalex.org/W2409483461","https://openalex.org/W4301504920","https://openalex.org/W2422432237","https://openalex.org/W2404604593","https://openalex.org/W2057415144","https://openalex.org/W2059056811","https://openalex.org/W2417710018"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}