{"id":"https://openalex.org/W2005373334","doi":"https://doi.org/10.1134/s0026893313010159","title":"Computational methods for predicting structure of membrane proteins using amino acid sequences","display_name":"Computational methods for predicting structure of membrane proteins using amino acid sequences","publication_year":2013,"publication_date":"2013-03-01","ids":{"openalex":"https://openalex.org/W2005373334","doi":"https://doi.org/10.1134/s0026893313010159","mag":"2005373334"},"language":"en","primary_location":{"id":"doi:10.1134/s0026893313010159","doi":"https://doi.org/10.1134/s0026893313010159","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s0026893313010159","pdf_url":null,"source":{"id":"https://openalex.org/S191406736","display_name":"Molecular Biology","issn_l":"0026-8933","issn":["0026-8933","0026-8984","1608-3245","3034-5553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016612931","display_name":"Maria N. Simakova","orcid":"https://orcid.org/0000-0003-2353-0779","observed_orcids":["https://orcid.org/0000-0003-2353-0779"]},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"M. N. Simakova","raw_affiliation_strings":["Institute of Complex Systems, Molecular Biophysics (ICS-5), Juelich Research Center, Juelich, 52425, Germany","Juelich Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Complex Systems, Molecular Biophysics (ICS-5), Juelich Research Center, Juelich, 52425, Germany","institution_ids":["https://openalex.org/I171892758"]},{"raw_affiliation_string":"Juelich Research Center","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065326031","display_name":"Nikolay N. Simakov","orcid":"https://orcid.org/0000-0003-4766-0615","observed_orcids":["https://orcid.org/0000-0003-4766-0615"]},"institutions":[{"id":"https://openalex.org/I4210112073","display_name":"Yaroslavl State Technical University","ror":"https://ror.org/022wdak15","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210112073"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. N. Simakov","raw_affiliation_strings":["Yaroslavl State Technical University, Yaroslavl, 150023, Russia","Yaroslavl State Technical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yaroslavl State Technical University, Yaroslavl, 150023, Russia","institution_ids":["https://openalex.org/I4210112073"]},{"raw_affiliation_string":"Yaroslavl State Technical University","institution_ids":["https://openalex.org/I4210112073"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5016612931"],"corresponding_institution_ids":["https://openalex.org/I171892758"],"apc_list":null,"apc_paid":null,"fwci":0.2199,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.49476651,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"47","issue":"2","first_page":"307","last_page":"315"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.6654999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.6654999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.32519999146461487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/membrane-protein-structure-prediction","display_name":"membrane protein structure prediction","score":0.8809999823570251},{"id":"https://openalex.org/keywords/transmembrane-proteins","display_name":"transmembrane proteins","score":0.9480000138282776},{"id":"https://openalex.org/keywords/polytopic-membrane-proteins","display_name":"polytopic membrane proteins","score":0.7720000147819519},{"id":"https://openalex.org/keywords/protein-secondary-structure-prediction","display_name":"secondary structure prediction","score":0.8180000185966492},{"id":"https://openalex.org/keywords/hydrophobic-amino-acids","display_name":"hydrophobic amino acids","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.8095693588256836},{"id":"https://openalex.org/C118892022","wikidata":"https://www.wikidata.org/wiki/Q7834587","display_name":"Transmembrane domain","level":3,"score":0.6484963297843933},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.6397230625152588},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.6362922191619873},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5568032264709473},{"id":"https://openalex.org/C2776141515","wikidata":"https://www.wikidata.org/wiki/Q1274479","display_name":"Repetition (rhetorical device)","level":2,"score":0.5492992401123047},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.5225676894187927},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.45859020948410034},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4443745017051697},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.395328164100647},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38036036491394043},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.37842029333114624},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.35550761222839355},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35445183515548706},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29244136810302734},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.11903449892997742},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1134/s0026893313010159","doi":"https://doi.org/10.1134/s0026893313010159","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s0026893313010159","pdf_url":null,"source":{"id":"https://openalex.org/S191406736","display_name":"Molecular Biology","issn_l":"0026-8933","issn":["0026-8933","0026-8984","1608-3245","3034-5553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W21542175","https://openalex.org/W166318893","https://openalex.org/W1972944746","https://openalex.org/W1975304761","https://openalex.org/W1985854865","https://openalex.org/W1997870466","https://openalex.org/W2008476021","https://openalex.org/W2026582002","https://openalex.org/W2027120710","https://openalex.org/W2027888174","https://openalex.org/W2059460565","https://openalex.org/W2065510140","https://openalex.org/W2083998431","https://openalex.org/W2086532312","https://openalex.org/W2142753274","https://openalex.org/W2144112248","https://openalex.org/W2157873167","https://openalex.org/W2167856604","https://openalex.org/W2473786023","https://openalex.org/W2562716764","https://openalex.org/W2624183933","https://openalex.org/W4240453720","https://openalex.org/W4297822793","https://openalex.org/W6652562992"],"related_works":["https://openalex.org/W2402998756","https://openalex.org/W78325576","https://openalex.org/W2038286066","https://openalex.org/W2050524321","https://openalex.org/W2102100633","https://openalex.org/W2468547612","https://openalex.org/W2498999788","https://openalex.org/W6981092112","https://openalex.org/W2128039894","https://openalex.org/W1235738081"],"abstract_inverted_index":{"The":[0,22,43],"structure":[1,160],"of":[2,19,24,29,39,59,65,84,89,105,113,124,146,161],"membrane":[3,41],"proteins":[4,80,142,163],"specifies":[5],"their":[6],"functional":[7,167],"properties,":[8],"which":[9],"are":[10],"important":[11],"for":[12,77,82,144,156],"medicine":[13],"and":[14,36,148,164],"pharmacology":[15],"and,":[16],"therefore,":[17],"is":[18,33,92],"significant":[20],"interest.":[21],"repetition":[23,45,88],"transmembrane":[25,79,90,141],"regions":[26,91],"that":[27,101,128],"consist":[28],"hydrophobic":[30],"amino":[31,62,126],"acids":[32,127],"a":[34,56,66,119],"characteristic":[35],"organic":[37],"feature":[38],"polytopic":[40],"proteins.":[42],"ordered":[44],"(periodicity)":[46],"can":[47,95],"be":[48,96],"detected":[49],"by":[50,98],"the":[51,60,69,87,103,106,114,122,131,139,153,158,165],"Fourier":[52,154],"method":[53,104,135,155],"applied":[54,137],"to":[55,109,138],"digital":[57],"image":[58],"symbolic":[61],"acid":[63],"sequence":[64],"protein.":[67],"In":[68],"present":[70],"work,":[71],"this":[72],"investigation":[73],"was":[74,136],"carried":[75],"out":[76],"24":[78,140],"(successfully":[81,143],"14":[83],"them).":[85],"If":[86],"aperiodic,":[93],"it":[94],"revealed":[97],"another":[99],"method,":[100],"is,":[102],"reiterated":[107],"(four":[108],"five":[110],"times)":[111],"averaging":[112],"protein":[115],"hydrophobicity":[116],"function":[117],"in":[118],"window":[120],"within":[121],"limits":[123],"9\u201311":[125],"moves":[129],"along":[130],"sequence.":[132],"This":[133],"novel":[134],"19":[145],"them)":[147],"demonstrated":[149],"higher":[150],"suitability":[151],"than":[152],"predicting":[157],"secondary":[159],"these":[162],"corresponding":[166],"properties.":[168]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2016-06-24T00:00:00"}