{"id":"https://openalex.org/W2005349781","doi":"https://doi.org/10.3109/10641963.2013.863322","title":"Role of propolis on biochemical parameters in kidney and heart tissues against l -NAME induced oxidative injury in rats","display_name":"Role of propolis on biochemical parameters in kidney and heart tissues against l -NAME induced oxidative injury in rats","publication_year":2014,"publication_date":"2014-02-03","ids":{"openalex":"https://openalex.org/W2005349781","doi":"https://doi.org/10.3109/10641963.2013.863322","mag":"2005349781","pmid":"https://pubmed.ncbi.nlm.nih.gov/24490594"},"language":"en","primary_location":{"id":"doi:10.3109/10641963.2013.863322","doi":"https://doi.org/10.3109/10641963.2013.863322","is_oa":false,"landing_page_url":"https://doi.org/10.3109/10641963.2013.863322","pdf_url":null,"source":{"id":"https://openalex.org/S203233286","display_name":"Clinical and Experimental Hypertension","issn_l":"0148-3927","issn":["0148-3927","0730-0077","1064-1963","1525-6006"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Hypertension","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085967423","display_name":"Zeliha Selamo\u011flu","orcid":"https://orcid.org/0000-0001-9056-6435","observed_orcids":["https://orcid.org/0000-0001-9056-6435","https://orcid.org/0009-0000-4132-4616"]},"institutions":[{"id":"https://openalex.org/I198265615","display_name":"Ni\u011fde \u00d6mer Halisdemir \u00dcniversitesi","ror":"https://ror.org/03ejnre35","country_code":"TR","type":"education","lineage":["https://openalex.org/I198265615"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Zeliha Selamoglu Talas","raw_affiliation_strings":["Department of Biology, Faculty of Arts and Sciences, Nigde University, Nigde, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Arts and Sciences, Nigde University, Nigde, Turkey","institution_ids":["https://openalex.org/I198265615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101616620","display_name":"\u0130lknur \u00d6zdemir","orcid":"https://orcid.org/0000-0002-8566-8979","observed_orcids":["https://orcid.org/0000-0002-8566-8979"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ilknur Ozdemir","raw_affiliation_strings":["Department of Chemistry, Faculty of Arts and Sciences, Inonu University MalatyaTurkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Arts and Sciences, Inonu University MalatyaTurkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040095531","display_name":"Osman \u00c7ift\u00e7i","orcid":"https://orcid.org/0000-0001-5755-3560","observed_orcids":["https://orcid.org/0000-0001-5755-3560","https://orcid.org/0000-0003-1384-4598"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Osman Ciftci","raw_affiliation_strings":["Department of Pharmacy Faculty, Inonu University MalatyaTurkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Faculty, Inonu University MalatyaTurkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022270345","display_name":"O\u011fuz \u00c7ak\u0131r","orcid":"https://orcid.org/0000-0002-8006-2054","observed_orcids":["https://orcid.org/0000-0002-8006-2054"]},"institutions":[{"id":"https://openalex.org/I123466251","display_name":"Dicle University","ror":"https://ror.org/0257dtg16","country_code":"TR","type":"education","lineage":["https://openalex.org/I123466251"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Oguz Cakir","raw_affiliation_strings":["Department of Science and Technology Research Application Center Dicle University DiyarbakirTurkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science and Technology Research Application Center Dicle University DiyarbakirTurkey","institution_ids":["https://openalex.org/I123466251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083461799","display_name":"Mehmet Fuat G\u00fclhan","orcid":"https://orcid.org/0000-0003-4838-1597","observed_orcids":["https://orcid.org/0000-0003-4838-1597"]},"institutions":[{"id":"https://openalex.org/I198265615","display_name":"Ni\u011fde \u00d6mer Halisdemir \u00dcniversitesi","ror":"https://ror.org/03ejnre35","country_code":"TR","type":"education","lineage":["https://openalex.org/I198265615"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehmet Fuat Gulhan","raw_affiliation_strings":["Department of Biology, Faculty of Arts and Sciences, Nigde University NigdeTurkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Arts and Sciences, Nigde University NigdeTurkey","institution_ids":["https://openalex.org/I198265615"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083050935","display_name":"Oguz Murat Pasaoglu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I198265615","display_name":"Ni\u011fde \u00d6mer Halisdemir \u00dcniversitesi","ror":"https://ror.org/03ejnre35","country_code":"TR","type":"education","lineage":["https://openalex.org/I198265615"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Oguz Murat Pasaoglu","raw_affiliation_strings":["Department of Biology, Faculty of Arts and Sciences, Nigde University NigdeTurkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Arts and Sciences, Nigde University NigdeTurkey","institution_ids":["https://openalex.org/I198265615"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5085967423"],"corresponding_institution_ids":["https://openalex.org/I198265615"],"apc_list":null,"apc_paid":null,"fwci":2.4905,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.87249971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"36","issue":"7","first_page":"492","last_page":"496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.07540000230073929,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/propolis","display_name":"propolis","score":1.0},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7979999780654907},{"id":"https://openalex.org/keywords/endothelial-nitric-oxide-synthase","display_name":"endothelial nitric oxide synthase","score":0.8840000033378601},{"id":"https://openalex.org/keywords/l-name","display_name":"L-NAME","score":0.8220000267028809},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8019999861717224},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7440000176429749},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.8920000195503235},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.9929999709129333},{"id":"https://openalex.org/keywords/kidney","display_name":"kidney","score":0.675000011920929},{"id":"https://openalex.org/keywords/heart","display_name":"heart","score":0.9800000190734863},{"id":"https://openalex.org/keywords/nitric-oxide-bioavailability","display_name":"nitric oxide bioavailability","score":0.8119999766349792},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C2780488879","wikidata":"https://www.wikidata.org/wiki/Q184398","display_name":"Propolis","level":2,"score":0.916374921798706},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6585988998413086},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.652974545955658},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.6521552801132202},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.6273590326309204},{"id":"https://openalex.org/C2778979269","wikidata":"https://www.wikidata.org/wiki/Q106951292","display_name":"Catalase","level":3,"score":0.5877455472946167},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5461188554763794},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.5016796588897705},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4700820744037628},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.46785977482795715},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.46492981910705566},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4082191586494446},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3558647334575653},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32514292001724243},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.1975366473197937}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002374","descriptor_name":"Catalase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006335","descriptor_name":"Heart Injuries","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006335","descriptor_name":"Heart Injuries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008315","descriptor_name":"Malondialdehyde","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011429","descriptor_name":"Propolis","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019001","descriptor_name":"Nitric Oxide Synthase","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D019331","descriptor_name":"NG-Nitroarginine Methyl Ester","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3109/10641963.2013.863322","doi":"https://doi.org/10.3109/10641963.2013.863322","is_oa":false,"landing_page_url":"https://doi.org/10.3109/10641963.2013.863322","pdf_url":null,"source":{"id":"https://openalex.org/S203233286","display_name":"Clinical and Experimental Hypertension","issn_l":"0148-3927","issn":["0148-3927","0730-0077","1064-1963","1525-6006"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Hypertension","raw_type":"journal-article"},{"id":"pmid:24490594","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24490594","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental hypertension (New York, N.Y. : 1993)","raw_type":"Journal Article"},{"id":"pmh:oai:acikerisim.ohu.edu.tr:11480/4229","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.3109/10641963.2013.863322","pdf_url":null,"source":{"id":"https://openalex.org/S7407055360","display_name":"Ni\u011fde \u00dcniversitesi A\u00e7\u0131k Eri\u015fim Sistemi","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311015","display_name":"Firat \u00dcniversitesi","ror":"https://ror.org/05teb7b63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W140930958","https://openalex.org/W179830025","https://openalex.org/W191793640","https://openalex.org/W1571856980","https://openalex.org/W1775749144","https://openalex.org/W1968037251","https://openalex.org/W1984986373","https://openalex.org/W1995782332","https://openalex.org/W2000145025","https://openalex.org/W2003292735","https://openalex.org/W2011200561","https://openalex.org/W2024440751","https://openalex.org/W2024938911","https://openalex.org/W2036885320","https://openalex.org/W2040630574","https://openalex.org/W2051698062","https://openalex.org/W2063854853","https://openalex.org/W2067116729","https://openalex.org/W2069296455","https://openalex.org/W2075638878","https://openalex.org/W2078391947","https://openalex.org/W2080203646","https://openalex.org/W2083043564","https://openalex.org/W2083771469","https://openalex.org/W2093822730","https://openalex.org/W2113798962","https://openalex.org/W2148071155","https://openalex.org/W2153269355","https://openalex.org/W2163975415","https://openalex.org/W2168846495","https://openalex.org/W2526259681","https://openalex.org/W4243261789"],"related_works":["https://openalex.org/W2526259681","https://openalex.org/W1560721086","https://openalex.org/W7219290291","https://openalex.org/W2184974066","https://openalex.org/W7219227253","https://openalex.org/W2749988255","https://openalex.org/W1970795704","https://openalex.org/W2954055223","https://openalex.org/W2748813901","https://openalex.org/W4404240581"],"abstract_inverted_index":{"Nitric":[0],"oxide":[1],"(NO),":[2],"produced":[3],"by":[4,46,73],"endothelial":[5,140],"NO":[6,48,69,103,141],"synthase,":[7],"is":[8],"recognised":[9],"as":[10,33,130],"a":[11,27],"central":[12],"antiinflammatory":[13],"and":[14,21,64,89,110],"antiatherogenic":[15],"principle":[16],"in":[17,62,84,92,107,121],"the":[18,36,85,93],"vasculature.":[19],"Epidemiological":[20],"clinical":[22],"studies":[23],"have":[24],"demonstrated":[25],"that":[26],"growing":[28],"list":[29],"of":[30,35,57,67,87,124],"natural":[31],"products,":[32],"components":[34],"daily":[37],"diet":[38],"or":[39],"phytomedical":[40],"preparations,":[41],"may":[42,138],"improve":[43],"vascular":[44],"function":[45],"enhancing":[47],"bioavailability.":[49],"In":[50,135],"this":[51],"article,":[52],"we":[53],"investigated":[54],"antioxidant":[55],"effects":[56],"propolis":[58,127,137],"on":[59],"biochemical":[60],"parameters":[61,123],"kidney":[63,109],"heart":[65,111],"tissues":[66],"acute":[68],"synthase":[70],"inhibited":[71],"rats":[72,129],"N\u03c9-nitro-l-arginine":[74],"methyl":[75],"ester":[76],"(l-NAME).":[77],"There":[78,113],"was":[79],"increase":[80],"(p":[81,118],"<":[82,119],"0.001)":[83,120],"activities":[86],"catalase":[88],"malondialdehyde":[90],"levels":[91,104],"l-NAME":[94,125],"treatment":[95],"groups":[96],"when":[97],"compared":[98,131],"with":[99,132],"control":[100],"rats,":[101],"but":[102],"were":[105,114],"decreased":[106],"both":[108],"tissues.":[112],"statistically":[115],"significant":[116],"changes":[117],"these":[122],"+":[126],"treated":[128],"l-NAME-treated":[133],"group.":[134],"summary,":[136],"influence":[139],"production.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}