{"id":"https://openalex.org/W2005346167","doi":"https://doi.org/10.1097/jom.0b013e3181715111","title":"Direct and Indirect Costs of Pain Therapy for Osteoarthritis in an Insured Population in the United States","display_name":"Direct and Indirect Costs of Pain Therapy for Osteoarthritis in an Insured Population in the United States","publication_year":2008,"publication_date":"2008-09-01","ids":{"openalex":"https://openalex.org/W2005346167","doi":"https://doi.org/10.1097/jom.0b013e3181715111","mag":"2005346167","pmid":"https://pubmed.ncbi.nlm.nih.gov/18784547"},"language":"en","primary_location":{"id":"doi:10.1097/jom.0b013e3181715111","doi":"https://doi.org/10.1097/jom.0b013e3181715111","is_oa":false,"landing_page_url":"https://doi.org/10.1097/jom.0b013e3181715111","pdf_url":null,"source":{"id":"https://openalex.org/S156862075","display_name":"Journal of Occupational and Environmental Medicine","issn_l":"1076-2752","issn":["1076-2752","1536-5948"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Occupational & Environmental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112649709","display_name":"Alan G. White","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405271437","display_name":"Ortho-McNeil Pharmaceutical (United States)","ror":"https://ror.org/02e7e3t27","country_code":"US","type":"company","lineage":["https://openalex.org/I4405271437"]},{"id":"https://openalex.org/I79463011","display_name":"Analysis Group (United States)","ror":"https://ror.org/044jp1563","country_code":"US","type":"company","lineage":["https://openalex.org/I79463011"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alan G. White","raw_affiliation_strings":["Analysis Group, Inc., Boston, MA 02199, USA. AWhite@analysisgroup.com","CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Analysis Group, Inc., Boston, MA 02199, USA. AWhite@analysisgroup.com","institution_ids":["https://openalex.org/I79463011"]},{"raw_affiliation_string":"CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ","institution_ids":["https://openalex.org/I4405271437","https://openalex.org/I79463011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111579901","display_name":"Howard G. Birnbaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405271437","display_name":"Ortho-McNeil Pharmaceutical (United States)","ror":"https://ror.org/02e7e3t27","country_code":"US","type":"company","lineage":["https://openalex.org/I4405271437"]},{"id":"https://openalex.org/I79463011","display_name":"Analysis Group (United States)","ror":"https://ror.org/044jp1563","country_code":"US","type":"company","lineage":["https://openalex.org/I79463011"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Howard G. Birnbaum","raw_affiliation_strings":["From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","institution_ids":["https://openalex.org/I79463011"]},{"raw_affiliation_string":"CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ","institution_ids":["https://openalex.org/I4405271437","https://openalex.org/I79463011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042316509","display_name":"Carmela C. Janagap","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405271437","display_name":"Ortho-McNeil Pharmaceutical (United States)","ror":"https://ror.org/02e7e3t27","country_code":"US","type":"company","lineage":["https://openalex.org/I4405271437"]},{"id":"https://openalex.org/I79463011","display_name":"Analysis Group (United States)","ror":"https://ror.org/044jp1563","country_code":"US","type":"company","lineage":["https://openalex.org/I79463011"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carmela Janagap","raw_affiliation_strings":["From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","institution_ids":["https://openalex.org/I79463011"]},{"raw_affiliation_string":"CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ","institution_ids":["https://openalex.org/I4405271437","https://openalex.org/I79463011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004673710","display_name":"Sharon Buteau","orcid":"https://orcid.org/0000-0002-4661-4652","observed_orcids":["https://orcid.org/0000-0002-4661-4652"]},"institutions":[{"id":"https://openalex.org/I4405271437","display_name":"Ortho-McNeil Pharmaceutical (United States)","ror":"https://ror.org/02e7e3t27","country_code":"US","type":"company","lineage":["https://openalex.org/I4405271437"]},{"id":"https://openalex.org/I79463011","display_name":"Analysis Group (United States)","ror":"https://ror.org/044jp1563","country_code":"US","type":"company","lineage":["https://openalex.org/I79463011"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharon Buteau","raw_affiliation_strings":["From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","institution_ids":["https://openalex.org/I79463011"]},{"raw_affiliation_string":"CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ","institution_ids":["https://openalex.org/I4405271437","https://openalex.org/I79463011"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012212211","display_name":"Jeff R. Schein","orcid":"https://orcid.org/0009-0006-7892-5005","observed_orcids":["https://orcid.org/0009-0006-7892-5005"]},"institutions":[{"id":"https://openalex.org/I4405271437","display_name":"Ortho-McNeil Pharmaceutical (United States)","ror":"https://ror.org/02e7e3t27","country_code":"US","type":"company","lineage":["https://openalex.org/I4405271437"]},{"id":"https://openalex.org/I79463011","display_name":"Analysis Group (United States)","ror":"https://ror.org/044jp1563","country_code":"US","type":"company","lineage":["https://openalex.org/I79463011"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeff Schein","raw_affiliation_strings":["From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass","institution_ids":["https://openalex.org/I79463011"]},{"raw_affiliation_string":"CME Available for this Article at ACOEM.org; E-mail: [email\u00a0protected].; From the Analysis Group, Inc. (Dr White, Dr Birnbaum, Ms Buteau), Boston, Mass; Ortho-McNeil Janssen Scientific Affairs, L.L.C. (Ms Janagap, Dr Schein), Raritan, NJ","institution_ids":["https://openalex.org/I4405271437","https://openalex.org/I79463011"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112649709"],"corresponding_institution_ids":["https://openalex.org/I4405271437","https://openalex.org/I79463011"],"apc_list":null,"apc_paid":null,"fwci":3.311,"has_fulltext":false,"cited_by_count":92,"citation_normalized_percentile":{"value":0.90886662,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"50","issue":"9","first_page":"998","last_page":"1005"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.8490999937057495,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.8490999937057495,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.05570000037550926,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.053599998354911804,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoarthritis","display_name":"osteoarthritis","score":1.0},{"id":"https://openalex.org/keywords/pain-management","display_name":"pain management","score":0.6809999942779541},{"id":"https://openalex.org/keywords/economic-burden","display_name":"economic burden","score":0.7379999756813049},{"id":"https://openalex.org/keywords/health-care-utilization","display_name":"health care utilization","score":0.8309999704360962},{"id":"https://openalex.org/keywords/prescription-drugs","display_name":"prescription drugs","score":0.453000009059906},{"id":"https://openalex.org/keywords/tramadol","display_name":"tramadol","score":0.9279999732971191},{"id":"https://openalex.org/keywords/cox-2-inhibitors","display_name":"COX-2 inhibitors","score":0.9300000071525574},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":1.0},{"id":"https://openalex.org/keywords/work-loss-costs","display_name":"work loss costs","score":0.7789999842643738},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.8349999785423279},{"id":"https://openalex.org/keywords/employer-sponsored-health-insurance","display_name":"employer-sponsored health insurance","score":0.40299999713897705}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8491373062133789},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.7223021388053894},{"id":"https://openalex.org/C6964187","wikidata":"https://www.wikidata.org/wiki/Q659256","display_name":"Indirect costs","level":2,"score":0.6950080394744873},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.6259493827819824},{"id":"https://openalex.org/C2779777798","wikidata":"https://www.wikidata.org/wiki/Q407592","display_name":"Tramadol","level":3,"score":0.5765887498855591},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.5367952585220337},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.53007972240448},{"id":"https://openalex.org/C3019354653","wikidata":"https://www.wikidata.org/wiki/Q5690885","display_name":"Medical costs","level":3,"score":0.512435257434845},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.4912082552909851},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4853042960166931},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.45300260186195374},{"id":"https://openalex.org/C2778858636","wikidata":"https://www.wikidata.org/wiki/Q1643563","display_name":"Prescription drug","level":3,"score":0.4437211751937866},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4257887303829193},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3309571146965027},{"id":"https://openalex.org/C2780820201","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic","level":2,"score":0.25761842727661133},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.23331311345100403},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1624075472354889},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.15062302350997925},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.11390170454978943},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D003365","descriptor_name":"Costs and Cost Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003365","descriptor_name":"Costs and Cost Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003365","descriptor_name":"Costs and Cost Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007345","descriptor_name":"Insurance Claim Review","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007345","descriptor_name":"Insurance Claim Review","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007345","descriptor_name":"Insurance Claim Review","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014147","descriptor_name":"Tramadol","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D014147","descriptor_name":"Tramadol","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D014147","descriptor_name":"Tramadol","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017281","descriptor_name":"Cost of Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017281","descriptor_name":"Cost of Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017281","descriptor_name":"Cost of Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019458","descriptor_name":"Insurance Coverage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019458","descriptor_name":"Insurance Coverage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019458","descriptor_name":"Insurance Coverage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051546","descriptor_name":"Cyclooxygenase 2","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D051546","descriptor_name":"Cyclooxygenase 2","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D051546","descriptor_name":"Cyclooxygenase 2","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/jom.0b013e3181715111","doi":"https://doi.org/10.1097/jom.0b013e3181715111","is_oa":false,"landing_page_url":"https://doi.org/10.1097/jom.0b013e3181715111","pdf_url":null,"source":{"id":"https://openalex.org/S156862075","display_name":"Journal of Occupational and Environmental Medicine","issn_l":"1076-2752","issn":["1076-2752","1536-5948"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Occupational & Environmental Medicine","raw_type":"journal-article"},{"id":"pmid:18784547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18784547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of occupational and environmental medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.49000000953674316,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W121452401","https://openalex.org/W1814996634","https://openalex.org/W1972460143","https://openalex.org/W2059663124","https://openalex.org/W2065256586","https://openalex.org/W2078314652","https://openalex.org/W2103637716","https://openalex.org/W2140215285","https://openalex.org/W2157229623","https://openalex.org/W2165638511","https://openalex.org/W2397864322","https://openalex.org/W2409984942","https://openalex.org/W2421228811","https://openalex.org/W2610860323","https://openalex.org/W4235941802","https://openalex.org/W4243296942"],"related_works":["https://openalex.org/W4383227143","https://openalex.org/W2281402649","https://openalex.org/W2047934579","https://openalex.org/W2895091242","https://openalex.org/W4306688351","https://openalex.org/W1989473858","https://openalex.org/W2313016284","https://openalex.org/W1965349033","https://openalex.org/W2137797277","https://openalex.org/W99120154"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"assess":[2],"the":[3,19,24,120],"health":[4,26],"care":[5,27],"utilization":[6],"and":[7,28,55,97,105,123,126,129],"cost":[8],"of":[9,31,37,88],"illness":[10],"for":[11],"osteoarthritis":[12],"(OA)":[13],"patients":[14,40,72,84],"taking":[15],"pain":[16,49],"medications.":[17],"Specifically,":[18],"goals":[20],"were":[21,64,73,102],"to":[22,43,80],"estimate":[23],"direct":[25,94],"indirect":[29,98],"costs":[30,63,101,125],"OA.":[32],"METHODS:":[33],"A":[34],"claims":[35],"database":[36],"privately":[38],"insured":[39],"was":[41,110],"used":[42],"identify":[44],"OA":[45,71,83,117],"patients.":[46],"Prescription":[47],"drug":[48],"treatments":[50],"included":[51],"tramadol,":[52],"cyclooxygenase-II":[53],"inhibitors,":[54],"nonsteroidal":[56],"anti-inflammatory":[57],"drugs.":[58],"Mean":[59],"annual":[60,93],"per":[61],"patient":[62],"calculated":[65],"from":[66,119],"an":[67],"employer's":[68],"perspective.":[69],"RESULTS:":[70],"prescribed":[74],"multiple":[75],"drugs":[76],"simultaneously":[77],"and/or":[78],"sequentially":[79],"manage":[81],"pain.":[82],"had":[85],"a":[86,111],"number":[87],"prevalent":[89],"comorbid":[90],"conditions.":[91],"Average":[92],"medical,":[95,122],"drug,":[96,121],"work":[99],"loss":[100],"$8601,":[103],"$2941,":[104],"$4603,":[106],"respectively.":[107],"CONCLUSIONS:":[108],"There":[109],"substantial":[112],"payer":[113],"burden":[114],"associated":[115],"with":[116],"resulting":[118],"disability":[124],"OA-related":[127],"comorbidities":[128],"high":[130],"concomitant":[131],"medication":[132],"utilization.":[133]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}