{"id":"https://openalex.org/W2005336629","doi":"https://doi.org/10.7600/jspfsm.60.295","title":"EFFECTS OF ACUTE PROLONGED STRENUOUS EXERCISE ON THE SALIVARY STRESS MARKERS AND INFLAMMATORY CYTOKINES","display_name":"EFFECTS OF ACUTE PROLONGED STRENUOUS EXERCISE ON THE SALIVARY STRESS MARKERS AND INFLAMMATORY CYTOKINES","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2005336629","doi":"https://doi.org/10.7600/jspfsm.60.295","mag":"2005336629"},"language":"en","primary_location":{"id":"doi:10.7600/jspfsm.60.295","doi":"https://doi.org/10.7600/jspfsm.60.295","is_oa":true,"landing_page_url":"https://doi.org/10.7600/jspfsm.60.295","pdf_url":"https://www.jstage.jst.go.jp/article/jspfsm/60/3/60_3_295/_pdf","source":{"id":"https://openalex.org/S4306543457","display_name":"\u4f53\u529b\u79d1\u5b78","issn_l":"0039-906X","issn":["0039-906X","1881-4751"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Physical Fitness and Sports Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/jspfsm/60/3/60_3_295/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"TATSUYA USUI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TATSUYA USUI","raw_affiliation_strings":["Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101636615","display_name":"Takahiro Yoshikawa","orcid":"https://orcid.org/0000-0002-8175-5880","observed_orcids":["https://orcid.org/0000-0002-8175-5880"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAKAHIRO YOSHIKAWA","raw_affiliation_strings":["Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110824694","display_name":"Shin-ya Ueda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286384","display_name":"National Cerebral and Cardiovascular Center Research Institute","ror":"https://ror.org/01zywn143","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210111404","https://openalex.org/I4405286384"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"SHIN-YA UEDA","raw_affiliation_strings":["National Cerebral and Cardiovascular Center Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cerebral and Cardiovascular Center Research Institute","institution_ids":["https://openalex.org/I4405286384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103236739","display_name":"Yoshihiro Katsura","orcid":"https://orcid.org/0000-0002-5412-0732","observed_orcids":["https://orcid.org/0000-0002-5412-0732"]},"institutions":[{"id":"https://openalex.org/I116465919","display_name":"Kogakuin University","ror":"https://ror.org/01wc2tq75","country_code":"JP","type":"education","lineage":["https://openalex.org/I116465919"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YOSHIHIRO KATSURA","raw_affiliation_strings":["Kogakuin University, Common Course, Department of Health and Physical Education"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kogakuin University, Common Course, Department of Health and Physical Education","institution_ids":["https://openalex.org/I116465919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108420376","display_name":"Keisuke Orita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KEISUKE ORITA","raw_affiliation_strings":["Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110751504","display_name":"Shigeo Fujimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"SHIGEO FUJIMOTO","raw_affiliation_strings":["Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6507,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.69167496,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"60","issue":"3","first_page":"295","last_page":"304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salivary-cortisol","display_name":"salivary cortisol","score":0.8820000290870667},{"id":"https://openalex.org/keywords/immunoglobulin-a","display_name":"immunoglobulin A","score":0.8930000066757202},{"id":"https://openalex.org/keywords/chromogranin-a","display_name":"chromogranin A","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9369999766349792},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9139999747276306},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":1.0},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/salivary-flow-rate","display_name":"salivary flow rate","score":0.9319999814033508},{"id":"https://openalex.org/keywords/exercise-stress-response","display_name":"exercise stress response","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.9145585298538208},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7484886050224304},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.68687504529953},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6822232007980347},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.5209516286849976},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.45713815093040466},{"id":"https://openalex.org/C11988809","wikidata":"https://www.wikidata.org/wiki/Q412889","display_name":"Interleukin 6","level":3,"score":0.4437847435474396},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.3321126103401184},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.32786983251571655}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7600/jspfsm.60.295","doi":"https://doi.org/10.7600/jspfsm.60.295","is_oa":true,"landing_page_url":"https://doi.org/10.7600/jspfsm.60.295","pdf_url":"https://www.jstage.jst.go.jp/article/jspfsm/60/3/60_3_295/_pdf","source":{"id":"https://openalex.org/S4306543457","display_name":"\u4f53\u529b\u79d1\u5b78","issn_l":"0039-906X","issn":["0039-906X","1881-4751"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Physical Fitness and Sports Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.7600/jspfsm.60.295","doi":"https://doi.org/10.7600/jspfsm.60.295","is_oa":true,"landing_page_url":"https://doi.org/10.7600/jspfsm.60.295","pdf_url":"https://www.jstage.jst.go.jp/article/jspfsm/60/3/60_3_295/_pdf","source":{"id":"https://openalex.org/S4306543457","display_name":"\u4f53\u529b\u79d1\u5b78","issn_l":"0039-906X","issn":["0039-906X","1881-4751"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Physical Fitness and Sports Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005336629.pdf","grobid_xml":"https://content.openalex.org/works/W2005336629.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W155479038","https://openalex.org/W1581415788","https://openalex.org/W1964517447","https://openalex.org/W1971412240","https://openalex.org/W1974167172","https://openalex.org/W1982819465","https://openalex.org/W1985839526","https://openalex.org/W1991432767","https://openalex.org/W1995444071","https://openalex.org/W2000150063","https://openalex.org/W2000497804","https://openalex.org/W2001120882","https://openalex.org/W2009389421","https://openalex.org/W2011321432","https://openalex.org/W2013847486","https://openalex.org/W2014893260","https://openalex.org/W2047177533","https://openalex.org/W2048837394","https://openalex.org/W2049196637","https://openalex.org/W2052006041","https://openalex.org/W2055973190","https://openalex.org/W2069965316","https://openalex.org/W2070150469","https://openalex.org/W2078085488","https://openalex.org/W2092239906","https://openalex.org/W2095172700","https://openalex.org/W2097805909","https://openalex.org/W2099138589","https://openalex.org/W2105661169","https://openalex.org/W2115419928","https://openalex.org/W2120658378","https://openalex.org/W2131825684","https://openalex.org/W2137217483","https://openalex.org/W2139434784","https://openalex.org/W2142126156","https://openalex.org/W2157554312","https://openalex.org/W2159569090","https://openalex.org/W2334696472","https://openalex.org/W2413624913"],"related_works":["https://openalex.org/W2075061399","https://openalex.org/W1869688177","https://openalex.org/W2272974691","https://openalex.org/W1982819465","https://openalex.org/W4394920303","https://openalex.org/W4294840777","https://openalex.org/W3174565168","https://openalex.org/W2060581788","https://openalex.org/W2955374481","https://openalex.org/W2795910926"],"abstract_inverted_index":{"The":[0,141],"aim":[1],"of":[2,11,66,148],"the":[3,101,117,129,139,157,175,201],"present":[4,142],"study":[5],"was":[6,93,98,134],"to":[7,182,199,204],"examine":[8],"whether":[9,184],"amount":[10],"oral":[12],"cortisol,":[13,159],"immunoglobulin":[14],"A":[15,18],"(IgA),":[16],"chromogranin":[17],"(CgA)":[19],"and":[20,72,83,88,95,106,109,115,123,137,161,169,190],"inflammatory":[21,75,132,162,191],"cytokines,":[22,76],"might":[23],"be":[24,194],"affected":[25],"by":[26],"prolonged":[27,149,206],"strenuous":[28,150,207],"exercise.":[29,103,130,140,176,208],"Ten":[30],"young":[31],"male":[32],"volunteers":[33],"either":[34],"exercised":[35],"on":[36],"recumbent":[37],"ergometer":[38],"at":[39,58],"75":[40],"%":[41],"VO2":[42],"max":[43],"for":[44,64],"60":[45,59],"min":[46,60],"(exercise":[47],"session)":[48],"or":[49,185],"sat":[50],"quietly":[51],"(resting":[52],"session).":[53],"Saliva":[54,90,104],"samples":[55],"were":[56,112,126,172],"obtained":[57],"intervals":[61],"during":[62,100,114,136],"sessions":[63],"measurements":[65],"salivary":[67,74,158,166,187],"stress":[68,188],"markers":[69,189,198],"(cortisol,":[70],"IgA":[71,121,167],"CgA),":[73],"such":[77],"as":[78,196],"interleukin-1\u03b2":[79],"(IL-1\u03b2),":[80],"interleukin-6":[81],"(IL-6)":[82],"tumor":[84],"necrosis":[85],"factor-\u03b1":[86],"(TNF-\u03b1)":[87],"osmolality.":[89],"flow":[91],"rate":[92],"decreased":[94,127,173],"saliva":[96,120],"osmolality":[97],"increased":[99,113,135],"60-min":[102],"cortisol":[105],"CgA":[107,160],"concentrations":[108],"secretion":[110,124,170],"rates":[111,125,171],"after":[116,128,138,174],"exercise,":[118],"whereas":[119,165],"concentration":[122,168],"Salivary":[131],"cytokines":[133,163,192],"findings":[143],"suggested":[144],"a":[145,153],"single":[146],"bout":[147],"exercise":[151],"caused":[152],"transient":[154],"increase":[155],"in":[156],"levels,":[164],"Further":[177],"studies,":[178],"however,":[179],"are":[180],"needed":[181],"delineate":[183],"not":[186],"may":[193],"used":[195],"biological":[197],"determine":[200],"host":[202],"responses":[203],"acute":[205]},"counts_by_year":[{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}