{"id":"https://openalex.org/W2005335768","doi":"https://doi.org/10.2170/jjphysiol.34.217","title":"High erythroid burst-promoting activity in sera from umbilical cord blood.","display_name":"High erythroid burst-promoting activity in sera from umbilical cord blood.","publication_year":1984,"publication_date":"1984-01-01","ids":{"openalex":"https://openalex.org/W2005335768","doi":"https://doi.org/10.2170/jjphysiol.34.217","mag":"2005335768","pmid":"https://pubmed.ncbi.nlm.nih.gov/6471610"},"language":"en","primary_location":{"id":"doi:10.2170/jjphysiol.34.217","doi":"https://doi.org/10.2170/jjphysiol.34.217","is_oa":true,"landing_page_url":"https://doi.org/10.2170/jjphysiol.34.217","pdf_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/34/2/34_2_217/_pdf","source":{"id":"https://openalex.org/S47046129","display_name":"The Japanese Journal of Physiology","issn_l":"0021-521X","issn":["0021-521X","1881-1396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4320800725","host_organization_name":"Physiological Society of Japan","host_organization_lineage":["https://openalex.org/P4320800725"],"host_organization_lineage_names":["Physiological Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese Journal of Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/34/2/34_2_217/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110083042","display_name":"Takashi Terasawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takashi TERASAWA","raw_affiliation_strings":["Department of Physiology, Tohoku Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Tohoku Dental University","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077264882","display_name":"Toshiharu Ito","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toshiharu ITO","raw_affiliation_strings":["Department of Physiology, Tohoku Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Tohoku Dental University","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102874044","display_name":"Minoru Matsuda","orcid":"https://orcid.org/0000-0001-5431-9891","observed_orcids":["https://orcid.org/0000-0001-5431-9891"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Minoru MATSUDA","raw_affiliation_strings":["Department of Physiology, Tohoku Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Tohoku Dental University","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071915691","display_name":"Tatsuro Azuma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257969","display_name":"Jusendo Hospital","ror":"https://ror.org/05wg82p98","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257969"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tatsuro AZUMA","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Jusendo General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Jusendo General Hospital","institution_ids":["https://openalex.org/I4405257969"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113737149","display_name":"Shiro Kasai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shiro KASAI","raw_affiliation_strings":["Department of Physiology, Tohoku Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Tohoku Dental University","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.279,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.54905928,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":"2","first_page":"217","last_page":"224"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.05090000107884407,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythroid-burst-formation","display_name":"erythroid burst formation","score":0.8379999995231628},{"id":"https://openalex.org/keywords/bfu-e","display_name":"BFU-E","score":0.9700000286102295},{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hemoglobin-synthesis","display_name":"hemoglobin synthesis","score":0.8669999837875366},{"id":"https://openalex.org/keywords/fetal-serum","display_name":"fetal serum","score":0.5189999938011169},{"id":"https://openalex.org/keywords/erythropoiesis","display_name":"erythropoiesis","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C2776955114","wikidata":"https://www.wikidata.org/wiki/Q172563","display_name":"Umbilical cord","level":2,"score":0.801403284072876},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4619925320148468},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.4559217095375061},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.4263589382171631},{"id":"https://openalex.org/C73591104","wikidata":"https://www.wikidata.org/wiki/Q603336","display_name":"Placenta cord banking","level":5,"score":0.41860896348953247},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3829537630081177},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.2856427729129791},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26913124322891235},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.242852121591568},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.17550989985466003},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001773","descriptor_name":"Blood Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004920","descriptor_name":"Erythropoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.2170/jjphysiol.34.217","doi":"https://doi.org/10.2170/jjphysiol.34.217","is_oa":true,"landing_page_url":"https://doi.org/10.2170/jjphysiol.34.217","pdf_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/34/2/34_2_217/_pdf","source":{"id":"https://openalex.org/S47046129","display_name":"The Japanese Journal of Physiology","issn_l":"0021-521X","issn":["0021-521X","1881-1396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4320800725","host_organization_name":"Physiological Society of Japan","host_organization_lineage":["https://openalex.org/P4320800725"],"host_organization_lineage_names":["Physiological Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese Journal of Physiology","raw_type":"journal-article"},{"id":"pmid:6471610","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6471610","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese journal of physiology","raw_type":"Journal Article"},{"id":"mag:3006456754","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/130003477066","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.2170/jjphysiol.34.217","doi":"https://doi.org/10.2170/jjphysiol.34.217","is_oa":true,"landing_page_url":"https://doi.org/10.2170/jjphysiol.34.217","pdf_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/34/2/34_2_217/_pdf","source":{"id":"https://openalex.org/S47046129","display_name":"The Japanese Journal of Physiology","issn_l":"0021-521X","issn":["0021-521X","1881-1396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4320800725","host_organization_name":"Physiological Society of Japan","host_organization_lineage":["https://openalex.org/P4320800725"],"host_organization_lineage_names":["Physiological Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese Journal of Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005335768.pdf","grobid_xml":"https://content.openalex.org/works/W2005335768.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W80661615","https://openalex.org/W141790480","https://openalex.org/W166173422","https://openalex.org/W184066441","https://openalex.org/W307574227","https://openalex.org/W1508762409","https://openalex.org/W1997054434","https://openalex.org/W2010474135","https://openalex.org/W2025421644","https://openalex.org/W2031228074","https://openalex.org/W2100406695","https://openalex.org/W2109899235","https://openalex.org/W2154037033","https://openalex.org/W2166944694","https://openalex.org/W2229661026","https://openalex.org/W2333201856"],"related_works":["https://openalex.org/W2437693252","https://openalex.org/W2016964983","https://openalex.org/W2037361868","https://openalex.org/W2472144686","https://openalex.org/W2007895358","https://openalex.org/W2074859372","https://openalex.org/W2403546348","https://openalex.org/W141790480","https://openalex.org/W2395312586","https://openalex.org/W2396171461"],"abstract_inverted_index":{"Using":[0],"methylcellulose":[1],"clonal":[2],"cell":[3],"cultures,":[4],"we":[5],"examined":[6],"human":[7],"erythroid":[8,29,94,109,128,175,192],"burst-promoting":[9],"activity":[10],"(BPA)":[11],"in":[12,46,75,101,113,120,138],"sera":[13],"obtained":[14],"from":[15],"umbilical":[16],"cord":[17,43,79,90,117,141,149,171],"blood.":[18],"BPA":[19],"was":[20,136],"measured":[21],"on":[22,93,174],"the":[23,26,47,86,114,121,146,153,167,185,189],"basis":[24],"of":[25,28,49,69,89,123,127,134,148,155,170,184,191],"number":[27,68,154],"bursts":[30],"(BFU-E)":[31],"and":[32,71,85,152,157],"hemoglobin":[33,72,158],"synthesis":[34,73,159],"when":[35],"peripheral":[36],"blood":[37,44,80,91,118,142,150,172],"mononuclear":[38],"cells":[39],"were":[40,62,97,160],"cultured":[41,63],"with":[42,64,104,116],"serum":[45,58,81,92,119,151,173],"presence":[48],"1.0":[50],"U/ml":[51,106],"erythropoietin":[52],"(Epo)":[53],"at":[54,194],"low":[55,132],"fetal":[56],"calf":[57],"concentration":[59],"(10%).":[60],"Controls":[61],"adult":[65],"serum.":[66,143],"The":[67],"BFU-E":[70,156],"increased":[74],"culture":[76],"to":[77,131,181],"which":[78],"had":[82],"been":[83],"added,":[84],"enhancing":[87],"effects":[88,169],"burst":[95,129,176],"formation":[96,130,177],"more":[98],"pronounced":[99],"than":[100],"control":[102],"cultures":[103,115,139],"2.0":[105],"Epo.":[107,124],"No":[108],"bursts,":[110],"however,":[111],"grew":[112],"absence":[122],"Increased":[125],"sensitivity":[126],"concentrations":[133,147],"Epo":[135],"observed":[137],"containing":[140],"Dose-relationships":[144],"between":[145],"clearly":[161],"observed.":[162],"We":[163],"therefore":[164],"concluded":[165],"that":[166],"stimulatory":[168],"may":[178],"be":[179],"due":[180],"BPA,":[182],"one":[183],"factors":[186],"required":[187],"for":[188],"proliferation":[190],"precursors":[193],"an":[195],"early":[196],"stage.":[197]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}