{"id":"https://openalex.org/W2005278622","doi":"https://doi.org/10.1002/path.2212","title":"A candidate precursor to serous carcinoma that originates in the distal fallopian tube (J Pathol 2007; 211: 26\u201335)","display_name":"A candidate precursor to serous carcinoma that originates in the distal fallopian tube (J Pathol 2007; 211: 26\u201335)","publication_year":2007,"publication_date":"2007-08-09","ids":{"openalex":"https://openalex.org/W2005278622","doi":"https://doi.org/10.1002/path.2212","mag":"2005278622"},"language":"en","primary_location":{"id":"doi:10.1002/path.2212","doi":"https://doi.org/10.1002/path.2212","is_oa":true,"landing_page_url":"https://doi.org/10.1002/path.2212","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/path.2212","source":{"id":"https://openalex.org/S4394736614","display_name":"The Journal of Pathology","issn_l":"0022-3417","issn":["0022-3417","1096-9896"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/path.2212","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043077648","display_name":"Y Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065532717","display_name":"Alexander Miron","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Miron","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065593057","display_name":"Ronny Drapkin","orcid":"https://orcid.org/0000-0002-6912-6977","observed_orcids":["https://orcid.org/0000-0002-6912-6977"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Drapkin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103618488","display_name":"Marisa R. Nucci","orcid":"https://orcid.org/0009-0008-7371-5695","observed_orcids":["https://orcid.org/0009-0008-7371-5695"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MR Nucci","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064740298","display_name":"Fab\u00edola Medeiros","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Medeiros","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051255229","display_name":"Aasia Saleemuddin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Saleemuddin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005206482","display_name":"Judy Ellen Garber","orcid":"https://orcid.org/0000-0001-9449-3982","observed_orcids":["https://orcid.org/0000-0001-9449-3982"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Garber","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"C Birch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Birch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"H Mou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Mou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"RW Gordon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"RW Gordon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061753517","display_name":"Daniel William Cramer","orcid":"https://orcid.org/0000-0002-8024-3066","observed_orcids":["https://orcid.org/0000-0002-8024-3066"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"DW Cramer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066748955","display_name":"Frank McKeon","orcid":"https://orcid.org/0000-0002-7747-9983","observed_orcids":["https://orcid.org/0000-0002-7747-9983"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"FD McKeon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5055130061","display_name":"Christopher P. Crum","orcid":"https://orcid.org/0000-0001-7746-1436","observed_orcids":["https://orcid.org/0000-0001-7746-1436"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"CP Crum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5450,"currency":"USD","value_usd":5450},"apc_paid":null,"fwci":1.005,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.75781984,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"213","issue":"1","first_page":"116","last_page":"116"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.8604000210762024,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.8604000210762024,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.13349999487400055,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serous-carcinoma","display_name":"serous carcinoma","score":0.9039999842643738},{"id":"https://openalex.org/keywords/fallopian-tube","display_name":"oviduct","score":0.8450000286102295},{"id":"https://openalex.org/keywords/p53-immunostaining","display_name":"p53 immunostaining","score":0.8119999766349792},{"id":"https://openalex.org/keywords/brca-mutations","display_name":"BRCA mutations","score":0.6949999928474426},{"id":"https://openalex.org/keywords/prophylactic-salpingectomy","display_name":"prophylactic salpingectomy","score":0.8420000076293945},{"id":"https://openalex.org/keywords/high-risk-women","display_name":"high-risk women","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C2775883341","wikidata":"https://www.wikidata.org/wiki/Q1233836","display_name":"Fallopian tube","level":2,"score":0.7797025442123413},{"id":"https://openalex.org/C2777632260","wikidata":"https://www.wikidata.org/wiki/Q19000698","display_name":"Serous carcinoma","level":4,"score":0.7211017608642578},{"id":"https://openalex.org/C150173356","wikidata":"https://www.wikidata.org/wiki/Q6144101","display_name":"Serous fluid","level":2,"score":0.6771819591522217},{"id":"https://openalex.org/C2780194787","wikidata":"https://www.wikidata.org/wiki/Q4836333","display_name":"BRCA mutation","level":4,"score":0.6062910556793213},{"id":"https://openalex.org/C2777249960","wikidata":"https://www.wikidata.org/wiki/Q4818922","display_name":"Fallopian tube cancer","level":4,"score":0.5753571391105652},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5633925199508667},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.48488911986351013},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47730743885040283},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.419813334941864},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.41293489933013916},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3666238486766815},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.342966228723526},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32446300983428955},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/path.2212","doi":"https://doi.org/10.1002/path.2212","is_oa":true,"landing_page_url":"https://doi.org/10.1002/path.2212","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/path.2212","source":{"id":"https://openalex.org/S4394736614","display_name":"The Journal of Pathology","issn_l":"0022-3417","issn":["0022-3417","1096-9896"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pathology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/path.2212","doi":"https://doi.org/10.1002/path.2212","is_oa":true,"landing_page_url":"https://doi.org/10.1002/path.2212","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/path.2212","source":{"id":"https://openalex.org/S4394736614","display_name":"The Journal of Pathology","issn_l":"0022-3417","issn":["0022-3417","1096-9896"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7900000214576721}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005278622.pdf","grobid_xml":"https://content.openalex.org/works/W2005278622.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2759697580","https://openalex.org/W2149834266","https://openalex.org/W2167493426","https://openalex.org/W2112303498","https://openalex.org/W1554355970","https://openalex.org/W2622924522","https://openalex.org/W1989354370","https://openalex.org/W3111646260","https://openalex.org/W174565913","https://openalex.org/W3164149802"],"abstract_inverted_index":{"In":[0],"this":[1,62],"recent":[2],"paper,":[3],"the":[4,10,40,89,103,129,133,136,143],"frequency":[5,111],"of":[6,13,39,72,128,139],"p53":[7,66,97,106],"signatures":[8,107],"in":[9,21,46,91,112,142],"fallopian":[11,144],"tubes":[12],"BRCA+":[14,45],"women":[15,24,78,113],"was":[16,29],"recorded":[17],"as":[18,44,55],"24%":[19],"(10/24),":[20],"contrast":[22],"to":[23],"with":[25,79,114],"other":[26],"disorders,":[27],"which":[28],"33%":[30],"(19/58).":[31],"We":[32],"have":[33,108],"since":[34],"discovered":[35],"that":[36,105,135],"a":[37,57,109,117,124],"proportion":[38],"cases":[41,90],"originally":[42],"classified":[43],"our":[47,84,92],"high-risk":[48],"population":[49],"had":[50],"not":[51,101,147],"been":[52],"documented":[53,80,118],"genetically":[54],"having":[56],"BRCA":[58,81,119],"mutation.":[59,120],"To":[60],"address":[61],"error,":[63],"we":[64],"reviewed":[65],"immunostains":[67],"from":[68,77],"605":[69],"tissue":[70],"blocks":[71],"75":[73],"consecutive":[74],"prophylactic":[75],"salpingectomies":[76],"mutations":[82],"at":[83],"institution.":[85],"This":[86,99],"cohort":[87],"included":[88],"report;":[93],"37%":[94],"(28/75)":[95],"contained":[96],"signatures.":[98],"does":[100],"alter":[102],"conclusion":[104],"similar":[110],"and":[115,131],"without":[116],"However,":[121],"it":[122],"provides":[123],"more":[125],"accurate":[126],"estimate":[127],"latter":[130],"reiterates":[132],"hypothesis":[134],"initial":[137],"phase":[138],"serous":[140],"carcinogenesis":[141],"tube":[145],"is":[146],"BRCA-dependent.":[148]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}