{"id":"https://openalex.org/W2005258788","doi":"https://doi.org/10.1111/acel.12115","title":"Senescence-associated lncRNAs: senescence-associated long noncoding RNAs","display_name":"Senescence-associated lncRNAs: senescence-associated long noncoding RNAs","publication_year":2013,"publication_date":"2013-06-13","ids":{"openalex":"https://openalex.org/W2005258788","doi":"https://doi.org/10.1111/acel.12115","mag":"2005258788","pmid":"https://pubmed.ncbi.nlm.nih.gov/23758631","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3773026"},"language":"en","primary_location":{"id":"doi:10.1111/acel.12115","doi":"https://doi.org/10.1111/acel.12115","is_oa":true,"landing_page_url":"https://doi.org/10.1111/acel.12115","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12115","source":{"id":"https://openalex.org/S174672550","display_name":"Aging Cell","issn_l":"1474-9718","issn":["1474-9718","1474-9726","1474-9728"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12115","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064301050","display_name":"Kotb Abdelmohsen","orcid":"https://orcid.org/0000-0001-6240-5810","observed_orcids":["https://orcid.org/0000-0001-6240-5810"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kotb Abdelmohsen","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006877808","display_name":"Amaresh Chandra Panda","orcid":"https://orcid.org/0000-0003-3189-8995","observed_orcids":["https://orcid.org/0000-0003-3189-8995"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amaresh Panda","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073039727","display_name":"Min Ju Kang","orcid":"https://orcid.org/0000-0001-5040-1388","observed_orcids":["https://orcid.org/0000-0001-5040-1388"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Min-Ju Kang","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108572494","display_name":"Jason Z. Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Xu","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039039321","display_name":"Roza Selimyan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roza Selimyan","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013145287","display_name":"Je\u2010Hyun Yoon","orcid":"https://orcid.org/0000-0001-7615-8654","observed_orcids":["https://orcid.org/0000-0001-7615-8654"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Je-Hyun Yoon","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006152899","display_name":"Jennifer L. Martindale","orcid":"https://orcid.org/0000-0002-3234-6861","observed_orcids":["https://orcid.org/0000-0002-3234-6861"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer L. Martindale","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033469228","display_name":"Supriyo De","orcid":"https://orcid.org/0000-0002-2075-7655","observed_orcids":["https://orcid.org/0000-0002-2075-7655"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Supriyo De","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035455387","display_name":"William H. Wood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William H. Wood","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052081713","display_name":"Kevin G. Becker","orcid":"https://orcid.org/0000-0002-6794-6656","observed_orcids":["https://orcid.org/0000-0002-6794-6656"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin G. Becker","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044404083","display_name":"Myriam Gorospe","orcid":"https://orcid.org/0000-0001-5439-3434","observed_orcids":["https://orcid.org/0000-0001-5439-3434"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Myriam Gorospe","raw_affiliation_strings":["Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore; MD 21224; USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5044404083","https://openalex.org/A5064301050"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":{"value":3790,"currency":"USD","value_usd":3790},"fwci":6.238,"has_fulltext":true,"cited_by_count":211,"citation_normalized_percentile":{"value":0.9803315,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"12","issue":"5","first_page":"890","last_page":"900"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.03970000147819519,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/replicative-senescence","display_name":"replicative senescence","score":0.9710000157356262},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.9139999747276306},{"id":"https://openalex.org/keywords/wi-38-fibroblasts","display_name":"WI-38 fibroblasts","score":0.9020000100135803},{"id":"https://openalex.org/keywords/novel-lncrnas","display_name":"novel lncRNAs","score":0.7519999742507935},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.7580000162124634},{"id":"https://openalex.org/keywords/beta-galactosidase-activity","display_name":"beta-galactosidase activity","score":0.871999979019165},{"id":"https://openalex.org/keywords/cell-morphology","display_name":"cell morphology","score":0.6480000019073486},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.3019999861717224},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.4000000059604645}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8969718217849731},{"id":"https://openalex.org/C522857546","wikidata":"https://www.wikidata.org/wiki/Q2070979","display_name":"Senescence","level":2,"score":0.8749721050262451},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.7053430080413818},{"id":"https://openalex.org/C34957205","wikidata":"https://www.wikidata.org/wiki/Q277338","display_name":"Pseudogene","level":4,"score":0.6714991331100464},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6611009240150452},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5314784049987793},{"id":"https://openalex.org/C179255354","wikidata":"https://www.wikidata.org/wiki/Q284416","display_name":"Small nucleolar RNA","level":5,"score":0.5197933912277222},{"id":"https://openalex.org/C147724379","wikidata":"https://www.wikidata.org/wiki/Q2367421","display_name":"Piwi-interacting RNA","level":5,"score":0.5137808918952942},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5032019019126892},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.5013537406921387},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.49555766582489014},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4096148908138275},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.35288530588150024},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3405417203903198},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.19459089636802673},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.17941120266914368}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011544","descriptor_name":"Pseudogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016372","descriptor_name":"RNA, Antisense","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016372","descriptor_name":"RNA, Antisense","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D048708","descriptor_name":"Cell Growth Processes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1111/acel.12115","doi":"https://doi.org/10.1111/acel.12115","is_oa":true,"landing_page_url":"https://doi.org/10.1111/acel.12115","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12115","source":{"id":"https://openalex.org/S174672550","display_name":"Aging Cell","issn_l":"1474-9718","issn":["1474-9718","1474-9726","1474-9728"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging Cell","raw_type":"journal-article"},{"id":"pmid:23758631","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23758631","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging cell","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3147291","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3773026","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3773026","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3773026","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Aging Cell","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1111/acel.12115","doi":"https://doi.org/10.1111/acel.12115","is_oa":true,"landing_page_url":"https://doi.org/10.1111/acel.12115","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12115","source":{"id":"https://openalex.org/S174672550","display_name":"Aging Cell","issn_l":"1474-9718","issn":["1474-9718","1474-9726","1474-9728"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000890048","display_name":"Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis","funder_award_id":"ZIAAG000511","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005258788.pdf","grobid_xml":"https://content.openalex.org/works/W2005258788.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1546100573","https://openalex.org/W1967530175","https://openalex.org/W2008374869","https://openalex.org/W2010345740","https://openalex.org/W2024209230","https://openalex.org/W2030658020","https://openalex.org/W2039816251","https://openalex.org/W2047330128","https://openalex.org/W2058659458","https://openalex.org/W2058691182","https://openalex.org/W2059878940","https://openalex.org/W2069519394","https://openalex.org/W2077450385","https://openalex.org/W2084585383","https://openalex.org/W2087528029","https://openalex.org/W2087616533","https://openalex.org/W2089970049","https://openalex.org/W2098832713","https://openalex.org/W2099778594","https://openalex.org/W2107578668","https://openalex.org/W2108273756","https://openalex.org/W2116437342","https://openalex.org/W2119066197","https://openalex.org/W2124887931","https://openalex.org/W2131078803","https://openalex.org/W2138773756","https://openalex.org/W2141458291","https://openalex.org/W2145849521","https://openalex.org/W2145931730","https://openalex.org/W2148059692","https://openalex.org/W2154657480","https://openalex.org/W2156427445","https://openalex.org/W2162674813","https://openalex.org/W2163106706","https://openalex.org/W2163432085","https://openalex.org/W2166822567","https://openalex.org/W2171317581"],"related_works":["https://openalex.org/W2259197633","https://openalex.org/W2408730352","https://openalex.org/W2995644762","https://openalex.org/W4403625688","https://openalex.org/W3113169475","https://openalex.org/W2254791612","https://openalex.org/W1926685779","https://openalex.org/W4378783752","https://openalex.org/W4411539801","https://openalex.org/W2947519010"],"abstract_inverted_index":{"Noncoding":[0],"RNAs":[1,18],"include":[2],"small":[3,28],"transcripts,":[4],"such":[5],"as":[6],"microRNAs":[7],"and":[8,11,90,99,141,153,159],"piwi-interacting":[9],"RNAs,":[10],"a":[12,27],"wide":[13],"range":[14],"of":[15,30,129,132,151],"long":[16],"noncoding":[17],"(lncRNAs).":[19],"Although":[20],"many":[21],"lncRNAs":[22,31,41,49,89,107,155],"have":[23,32],"been":[24,33],"identified,":[25],"only":[26],"number":[29],"characterized":[34],"functionally.":[35],"Here,":[36],"we":[37],"sought":[38],"to":[39,119],"identify":[40],"differentially":[42],"expressed":[43,50,65],"during":[44],"replicative":[45],"senescence.":[46],"We":[47],"compared":[48],"in":[51,66,79,112,167],"proliferating,":[52],"early-passage,":[53],"'young'":[54],"human":[55],"diploid":[56],"WI-38":[57],"fibroblasts":[58,70],"[population":[59],"doubling":[60],"(PDL)":[61],"20]":[62],"with":[63,157],"those":[64],"senescent,":[67],"late-passage,":[68],"'old'":[69],"(PDL":[71],"52)":[72],"by":[73],"RNA":[74],"sequencing":[75],"(RNA-Seq).":[76],"Numerous":[77],"transcripts":[78],"all":[80],"lncRNA":[81],"groups":[82],"(antisense":[83],"lncRNAs,":[84,86],"pseudogene-encoded":[85],"previously":[87],"described":[88],"novel":[91,105,154],"lncRNAs)":[92],"were":[93],"validated":[94],"using":[95],"reverse":[96],"transcription":[97],"(RT)":[98],"real-time,":[100],"quantitative":[101],"(q)PCR.":[102],"Among":[103],"the":[104,127,149],"senescence-associated":[106],"(SAL-RNAs)":[108],"showing":[109],"lower":[110],"abundance":[111],"senescent":[113],"cells,":[114],"SAL-RNA1":[115,124],"(XLOC_023166)":[116],"was":[117],"found":[118],"delay":[120],"senescence,":[121,133],"because":[122],"reducing":[123],"levels":[125],"enhanced":[126],"appearance":[128],"phenotypic":[130],"traits":[131],"including":[134],"an":[135],"enlarged":[136],"morphology,":[137],"positive":[138],"\u03b2-galactosidase":[139],"activity,":[140],"heightened":[142],"p53":[143],"levels.":[144],"Our":[145],"results":[146],"reveal":[147],"that":[148,161],"expression":[150],"known":[152],"changes":[156],"senescence":[158],"suggests":[160],"SAL-RNAs":[162],"play":[163],"direct":[164],"regulatory":[165],"roles":[166],"this":[168],"important":[169],"cellular":[170],"process.":[171]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":31},{"year":2019,"cited_by_count":25},{"year":2018,"cited_by_count":18},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":20},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":13}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}